Synthesis and activity of enantiopure (S) (m-nitrobenzoyl) alanine, potent kynurenine-3-hydroxylase inhibitor

Bioorganic and Medicinal Chemistry Letters

Volumn 5, Issue 14, 1995, Pages 1451-1454

  Natalini, Benedetto ^a   Mattoli, Luisa ^a   Pellicciari, Roberto ^a   Carpenedo, Raffaella ^b   Chiarugi, Alberto ^b   Moroni, Flavio ^b  

^a UNIVERSITY OF PERUGIA   (Italy)

^b UNIVERSITY OF FLORENCE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

(3 NITROBENZOYL)ALANINE; ALANINE DERIVATIVE; KYNURENINASE; KYNURENINE; KYNURENINE 3 MONOOXYGENASE; KYNURENINE 3 MONOOXYGENASE INHIBITOR; OXYGENASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; COMPETITIVE INHIBITION; CONCENTRATION RESPONSE; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; ENZYME INHIBITION;

EID: 0029052731     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0960-894X(95)00255-R     Document Type: Article

References (9)

1. Preparation of aryltributyltin having electron-withdrawing group by palladium catalyzed reaction of hexabutylditin with aryl iodide.
2. I. Selective Protection of α- or Side-chain Carboxyl Groups of Aspartic and Glutamic Acid. A Facile Synthesis of β-Aspartyl and γ-Glutamyl Peptides
3. The Palladium-Catalyzed Cross-Coupling Reactions of Organotin Reagents with Organic Electrophiles[New Synthetic Methods(58)]