Tumor suppressor gene P53 mutations in human prostate cancer

The Prostate

Volumn 27, Issue 1, 1995, Pages 18-24

  Kubota, Yoshinobu ^a   Shuin, Taro ^a   Uemura, Hiroji ^a   Fujinami, Kiyoshi ^a   Miyamoto, Hiroshi ^a   Torigoe, Soichiro ^a   Dobashi, Yasushi ^a   Kitamura, Hitoshi ^a   Iwasaki, Yoshiko ^b   Danenberg, Kathleen ^c   Danenberg, Peter V ^c  

^a YOKOHAMA CITY UNIVERSITY   (Japan)

^b KANAGAWA DENTAL COLLEGE   (Japan)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

human prostate cancer; p53 gene; PCR; RNA SSCP analysis

Indexed keywords

DNA; PROTEIN P53; RNA;

ARTICLE; CANCER STAGING; CONTROLLED STUDY; DNA SEQUENCE; GENE DELETION; GENE MUTATION; HUMAN; HUMAN TISSUE; MALE; POINT MUTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROSTATE ADENOCARCINOMA; PROSTATE HYPERTROPHY; SINGLE STRAND CONFORMATION POLYMORPHISM; TUMOR DIFFERENTIATION; TUMOR SUPPRESSOR GENE;

ADENOCARCINOMA; BASE SEQUENCE; DNA, NEOPLASM; EXONS; GENES, P53; HUMAN; MALE; MOLECULAR SEQUENCE DATA; MUTATION; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; PROSTATIC NEOPLASMS; RNA, NEOPLASM; SUPPORT, NON-U.S. GOV'T;

EID: 0029049115     PISSN: 02704137     EISSN: 10970045     Source Type: Journal    
DOI: 10.1002/pros.2990270105     Document Type: Article

References (22)

1. Mutations in the p53 gene occur in diverse human tumor types
2. P53 gene mutations occur in combination with 17P alleic deletions as late events in colorectal tumorigenesis
3. Mutational hospot in the p53 gene in human hepatocellular carcinomas
4. Allelic loss of chromosomes 16q and 10q in human prostate cancer
5. Wild‐type p53 suppressor growth of human prostate cancer cells containing mutant p53 alleles
6. Small subgroup of aggressive highly proliferative prostatic carcinomas defined by p53 accumulation
7. p53 is mutated in a subset of advancedstage prostate cancers
8. Epidemiology of prostate cancer
9. Ras gene mutations in human prostate cancer
10. K‐ras activation and ras p21 expression in latent prostatic carcinoma in Japanese men
11. Detection of point mutations in DNA by analysis of RNA conformatinal polymorphism(s)
12. Single‐step method of RNA isolation by acid guanidium thiocyanate‐phenol‐chloroform extraction
13. Quantitation of thymidylate synthetase dihydrofolate reductase, and DT‐diaphorase gene expression in human tumors using the polymerase chain reaction
14. Characterization of human p53 gene
15. Alterations of the p53 gene are associated with the progression of a human prostate carcinoma
16. Patterns of progression in prostate cancer
17. P53 gene mutation in primary human renal cell carcinoma
18. Analysis of p53 gene mutations in primary human bladder cancer
19. NAD(P)H: Quinone oxidoreductase gene expression in human colon carcinoma cells: Characterization of a mutation which modurates DT‐diaphorase activity and mitomycin sensitivity