A one-step procedure for the selective trifluoroacetylation of primary amino groups of polyamines

Tetrahedron Letters

Volumn 36, Issue 20, 1995, Pages 3451-3452

  O'Sullivan, Mary C ^a   Dalrymple, Damon M ^a  

^a INDIANA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

POLYAMINE DERIVATIVE; TRIFLUOROACETAMIDE DERIVATIVE;

ARTICLE; DRUG SYNTHESIS; METHODOLOGY; REACTION ANALYSIS;

EID: 0029044308     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(95)00630-U     Document Type: Article

References (23)

1. Chemoselective acylation of primary amines in the presence of secondary amines with acyl cyanides. Highly efficient methods for the synthesis of spermidine and spermine alkaloid.
2. Total synthesis of parabactin, a spermidine siderophore
3. Targeting of cytotoxic agents by polyamines: synthesis of a chlorambucil?spermidine conjugate
4. Discrimination of spermidine amino functions by a new protecting group strategy; application to the synthesis of guanidinylated polyamines, including hirudonine