A second large controlled clinical study of E5, a monoclonal antibody to endotoxin: Results of a prospective, multicenter, randomized, controlled trial

Critical Care Medicine

Volumn 23, Issue 6, 1995, Pages 994-1006

  Bone, R C ^a   Balk, R A ^a   Fein, A M ^a   Perl, T M ^a   Wenzel, R P ^a   Reines, H D ^a   Quenzer, R W ^a   Iberti, T J ^a   Macintyre, N ^a   Schein, R M H ^a   Trenholme, G ^a   Niederman, M ^a   Chalfin, D ^a   Jebson, P ^a   Abalos, A ^a   Oropello, J ^a   Empson, P ^a   Caminitii, S ^a   Greenman, R ^a  

^a RUSH UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

bacteremia; critical illness; endotoxemia; endotoxin; Gram negative bacteria; interleukin 1; monoclonal antibody; randomized clinical trial; sepsis; tumor necrosis factor

Indexed keywords

ANTIBIOTIC AGENT; ENDOTOXIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY E5; PLACEBO; UNCLASSIFIED DRUG;

ADULT; ADULT RESPIRATORY DISTRESS SYNDROME; ANTIBODY RESPONSE; ARTICLE; CENTRAL NERVOUS SYSTEM DISEASE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG HYPERSENSITIVITY; FEMALE; GRAM NEGATIVE SEPSIS; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; MALE; MORTALITY; MULTICENTER STUDY; MULTIPLE ORGAN FAILURE; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; SURVIVAL;

EID: 0029043636     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-199506000-00003     Document Type: Article

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