-
1
-
-
0025832605
-
Multiple components in an epidermal growth factor-stimulated protein kinase cascade. in vitro activation of a myelin basic protein/microtubule-associated protein 2 kinase
-
Ahn, N.G., R. Seger, R.L. Bratlien, C.D. Diltz, N.K. Tonks, and E.G. Krebs. 1991. Multiple components in an epidermal growth factor-stimulated protein kinase cascade. In vitro activation of a myelin basic protein/microtubule-associated protein 2 kinase. J. Biol. Chem. 266: 4220-4227.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 4220-4227
-
-
Ahn, N.G.1
Seger, R.2
Bratlien, R.L.3
Diltz, C.D.4
Tonks, N.K.5
Krebs, E.G.6
-
2
-
-
0028228616
-
Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells
-
Cowley, S., H. Paterson, P. Kemp, and C.J. Marshall. 1994. Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells. Cell 77: 841-852.
-
(1994)
Cell
, vol.77
, pp. 841-852
-
-
Cowley, S.1
Paterson, H.2
Kemp, P.3
Marshall, C.J.4
-
3
-
-
0026641090
-
Activation of mitogen-activated protein kinase kinase by v-Raf in NIH 3T3 cells and in vitro
-
Dent, P., W. Haser, T.A.J. Haystead, L.A. Vincent, T.M. Robers, and T.W. Sturgill. 1992. Activation of mitogen-activated protein kinase kinase by v-Raf in NIH 3T3 cells and in vitro. Science 257: 1404-1407.
-
(1992)
Science
, vol.257
, pp. 1404-1407
-
-
Dent, P.1
Haser, W.2
Haystead, T.A.J.3
Vincent, L.A.4
Robers, T.M.5
Sturgill, T.W.6
-
4
-
-
0024267140
-
Human cdc2 protein kinase is a major cell-cycle regulated tyrosine kinase substrate
-
Draetta, G., H. Piwnica-Worms, D. Morrison, B. Druker, T. Roberts, and D. Beach. 1988. Human cdc2 protein kinase is a major cell-cycle regulated tyrosine kinase substrate. Nature 336: 738-744.
-
(1988)
Nature
, vol.336
, pp. 738-744
-
-
Draetta, G.1
Piwnica-Worms, H.2
Morrison, D.3
Druker, B.4
Roberts, T.5
Beach, D.6
-
5
-
-
0028220204
-
p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest
-
Dulic, V., W.K. Kaufmann, S.J. Wilson, T.D. Tlsty, E. Lees, J.W. Harper, S.J. Elledge, and S.I. Reed. 1994. p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest. Cell 76: 1013-1023.
-
(1994)
Cell
, vol.76
, pp. 1013-1023
-
-
Dulic, V.1
Kaufmann, W.K.2
Wilson, S.J.3
Tlsty, T.D.4
Lees, E.5
Harper, J.W.6
Elledge, S.J.7
Reed, S.I.8
-
6
-
-
0025938467
-
The cdc25 protein contains an intrinsic phosphatase activity
-
Dunphy, W.G. and A. Kumagai. 1991. The cdc25 protein contains an intrinsic phosphatase activity. Cell 67: 189-196.
-
(1991)
Cell
, vol.67
, pp. 189-196
-
-
Dunphy, W.G.1
Kumagai, A.2
-
7
-
-
0024395110
-
Fission yeast p13 blocks mitotic activation and tyrosine dephosphorylation of the Xenopus cdc2 protein kinase
-
Dunphy, W.G. and J.W. Newport. 1989. Fission yeast p13 blocks mitotic activation and tyrosine dephosphorylation of the Xenopus cdc2 protein kinase. Cell 58: 181-431.
-
(1989)
Cell
, vol.58
, pp. 181-431
-
-
Dunphy, W.G.1
Newport, J.W.2
-
8
-
-
0027359827
-
WAF1, a potential mediator of p53 tumor suppression
-
El-Deiry, W.S., T. Tokino, V.E. Velculescu, D.B. Levy, R. Parsons, J.M. Trent, D. Lin, W.E. Mercer, K.W. Kinzler, and B. Vogelstein. 1993. WAF1, a potential mediator of p53 tumor suppression. Cell 75: 817-825.
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
El-Deiry, W.S.1
Tokino, T.2
Velculescu, V.E.3
Levy, D.B.4
Parsons, R.5
Trent, J.M.6
Lin, D.7
Mercer, W.E.8
Kinzler, K.W.9
Vogelstein, B.10
-
9
-
-
0020961333
-
Cyclin: A protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage division
-
Evans, T., E.T. Rosenthal, J. Youngblom, D. Distel, and T. Hunt. 1983. Cyclin: A protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage division. Cell 33: 389-396.
-
(1983)
Cell
, vol.33
, pp. 389-396
-
-
Evans, T.1
Rosenthal, E.T.2
Youngblom, J.3
Distel, D.4
Hunt, T.5
-
10
-
-
0027184473
-
Requirement for Raf and MAP kinase function during the meiotic maturation of Xenopus oocytes
-
Fabian, J.R., D.K. Morrison, and I.O. Daar. 1993a. Requirement for Raf and MAP kinase function during the meiotic maturation of Xenopus oocytes. J. Cell Biol. 122: 645-652.
-
(1993)
J. Cell Biol.
, vol.122
, pp. 645-652
-
-
Fabian, J.R.1
Morrison, D.K.2
Daar, I.O.3
-
11
-
-
0027364980
-
Critical tyrosine residues regulate the enzymatic and biological activity of Raf-1 kinase
-
Fabian, J.R., I.O. Daar, and D.K. Morrison. 1993b. Critical tyrosine residues regulate the enzymatic and biological activity of Raf-1 kinase. Mol. Cell Biol. 13: 7170-7173.
-
(1993)
Mol. Cell Biol.
, vol.13
, pp. 7170-7173
-
-
Fabian, J.R.1
Daar, I.O.2
Morrison, D.K.3
-
12
-
-
0025924328
-
Fission yeast p107wee1 mitotic inhibitor is a tyrosine/serine kinase
-
Featherstone, C. and P. Russell. 1991. Fission yeast p107wee1 mitotic inhibitor is a tyrosine/serine kinase. Nature 349: 808-811.
-
(1991)
Nature
, vol.349
, pp. 808-811
-
-
Featherstone, C.1
Russell, P.2
-
13
-
-
0028073606
-
Binding of 14-3-3 proteins to the protein kinase Raf and effects on its activation
-
Freed, E., M. Symons, S.G. Macdonald, F. McCormick, and R. Ruggieri. 1994. Binding of 14-3-3 proteins to the protein kinase Raf and effects on its activation. Science 265: 1713-1716.
-
(1994)
Science
, vol.265
, pp. 1713-1716
-
-
Freed, E.1
Symons, M.2
Macdonald, S.G.3
McCormick, F.4
Ruggieri, R.5
-
14
-
-
0028115999
-
Interaction of the protein kinase Raf-1 with 14-3-3 proteins
-
Fu, H., K. Xia, D.C. Pallas, C. Cui, K. Conroy, R.P. Narsimhan, H. Mamon, R.J. Collier, and T.M. Roberts. 1994. Interaction of the protein kinase Raf-1 with 14-3-3 proteins. Science 266: 126-129.
-
(1994)
Science
, vol.266
, pp. 126-129
-
-
Fu, H.1
Xia, K.2
Pallas, D.C.3
Cui, C.4
Conroy, K.5
Narsimhan, R.P.6
Mamon, H.7
Collier, R.J.8
Roberts, T.M.9
-
15
-
-
0026319225
-
Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: Evidence for multiple roles of mitotic cyclins
-
Galaktionov, K. and D. Beach. 1991. Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: Evidence for multiple roles of mitotic cyclins. Cell 67: 1181-1194.
-
(1991)
Cell
, vol.67
, pp. 1181-1194
-
-
Galaktionov, K.1
Beach, D.2
-
16
-
-
0024976415
-
Dephosphorylation and activation of Xenopus p34cdc2 protein kinase during the cell cycle
-
Gautier, J., T. Matsukawa, P. Nurse, and J. Maller. 1989. Dephosphorylation and activation of Xenopus p34cdc2 protein kinase during the cell cycle. Nature 339: 626-629.
-
(1989)
Nature
, vol.339
, pp. 626-629
-
-
Gautier, J.1
Matsukawa, T.2
Nurse, P.3
Maller, J.4
-
17
-
-
0025936510
-
Cdc25 is a specific tyrosine phosphatase that directly activates p34cdc2
-
Gautier, J., M. Solomon, R. Booher, J. Bazan, and M. Kirshner. 1991. Cdc25 is a specific tyrosine phosphatase that directly activates p34cdc2. Cell 67: 197-211.
-
(1991)
Cell
, vol.67
, pp. 197-211
-
-
Gautier, J.1
Solomon, M.2
Booher, R.3
Bazan, J.4
Kirshner, M.5
-
18
-
-
0007713485
-
Dissection of the protein kinase cascade by which nerve growth factor activates MAP kinases
-
Gomez, N. and P. Cohen. 1991. Dissection of the protein kinase cascade by which nerve growth factor activates MAP kinases. Nature 351: 69-72.
-
(1991)
Nature
, vol.351
, pp. 69-72
-
-
Gomez, N.1
Cohen, P.2
-
19
-
-
0024959919
-
Tyrosine phosphorylation of the fission cdc2+ protein kinase regulates entry into mitosis
-
Gould, K. and P. Nurse. 1989. Tyrosine phosphorylation of the fission cdc2+ protein kinase regulates entry into mitosis. Nature 342: 39-45.
-
(1989)
Nature
, vol.342
, pp. 39-45
-
-
Gould, K.1
Nurse, P.2
-
20
-
-
0026713875
-
Cell cycle regulation of cdk2 activity by phosphorylation of Thr160 and Tyr15
-
Gu, Y., J. Rosenblatt, and D.O. Morgan. 1992. Cell cycle regulation of cdk2 activity by phosphorylation of Thr160 and Tyr15. EMBO J. 11: 3995-4005.
-
(1992)
EMBO J.
, vol.11
, pp. 3995-4005
-
-
Gu, Y.1
Rosenblatt, J.2
Morgan, D.O.3
-
21
-
-
0027731971
-
Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit
-
Gu, Y., C.W. Turck, and D.O. Morgan. 1993. Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit. Nature 366: 707-710.
-
(1993)
Nature
, vol.366
, pp. 707-710
-
-
Gu, Y.1
Turck, C.W.2
Morgan, D.O.3
-
22
-
-
0028582034
-
Growth suppression by p18, a p16ink4/MTS1-and p14 ink4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function
-
Guan, K.-L., C.W. Jenkins, Y. Li, M. Nichols, X. Wu, C. O'Keefe, A.G. Matera, and Y. Xiong. 1994. Growth suppression by p18, a p16ink4/MTS1-and p14 ink4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function. Genes & Development. 8: 2939-2952.
-
(1994)
Genes & Development
, vol.8
, pp. 2939-2952
-
-
Guan, K.-L.1
Jenkins, C.W.2
Li, Y.3
Nichols, M.4
Wu, X.5
O'Keefe, C.6
Matera, A.G.7
Xiong, Y.8
-
23
-
-
0027717965
-
Induction of the metaphase arrest in cleaving Xenopus embryos by MAP kinase
-
Haccard, O., B. Sarcevic, A. Lewellyn, R. Hartley, L. Roy, T. Izumi, E. Erikson, and J.L. Maller. 1993. Induction of the metaphase arrest in cleaving Xenopus embryos by MAP kinase. Science 262: 1262-1265.
-
(1993)
Science
, vol.262
, pp. 1262-1265
-
-
Haccard, O.1
Sarcevic, B.2
Lewellyn, A.3
Hartley, R.4
Roy, L.5
Izumi, T.6
Erikson, E.7
Maller, J.L.8
-
24
-
-
0028168242
-
p15INK4B is a potential effector of TGF-β mediated cell cycle arrest
-
Hannon, G.J. and D. Beach. 1994. p15INK4B is a potential effector of TGF-β mediated cell cycle arrest. Nature 371: 257-261.
-
(1994)
Nature
, vol.371
, pp. 257-261
-
-
Hannon, G.J.1
Beach, D.2
-
25
-
-
0027496935
-
The p21 cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
-
Harper, J.W., G.R. Adami, N. Wei, J. Keyomarsi, and S.J. Elledge. 1993. The p21 cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 75: 805-816.
-
(1993)
Cell
, vol.75
, pp. 805-816
-
-
Harper, J.W.1
Adami, G.R.2
Wei, N.3
Keyomarsi, J.4
Elledge, S.J.5
-
26
-
-
0027967944
-
Rules to replicate by
-
Heichman, K.A. and J. Roberts. 1994. Rules to replicate by. Cell 79: 557-562.
-
(1994)
Cell
, vol.79
, pp. 557-562
-
-
Heichman, K.A.1
Roberts, J.2
-
27
-
-
0025277489
-
Mutational activation of c-raf-1 and definition of the minimal transforming sequence
-
Heidecker, G., M. Huleihel, J.L. Cleveland, W. Kolch, T.W. Beck, P. Lloyd, T. Pawson, and U.R. Rapp. 1990. Mutational activation of c-raf-1 and definition of the minimal transforming sequence. Mol. Cell Biol 10: 2503-2512.
-
(1990)
Mol. Cell Biol
, vol.10
, pp. 2503-2512
-
-
Heidecker, G.1
Huleihel, M.2
Cleveland, J.L.3
Kolch, W.4
Beck, T.W.5
Lloyd, P.6
Pawson, T.7
Rapp, U.R.8
-
28
-
-
0026546604
-
The role of Raf-1 phosphorylation in signal transduction
-
Heidecker, G., W. Kolch, D.K. Morrison, and U.R. Rapp. 1991. The role of Raf-1 phosphorylation in signal transduction. Adv. Cancer Res. 58: 53-73.
-
(1991)
Adv. Cancer Res.
, vol.58
, pp. 53-73
-
-
Heidecker, G.1
Kolch, W.2
Morrison, D.K.3
Rapp, U.R.4
-
29
-
-
0028985079
-
MAP kinase pathways in yeast: For mating and more
-
Herskowitz, I. 1995. MAP kinase pathways in yeast: For mating and more. Cell 80: 187-197.
-
(1995)
Cell
, vol.80
, pp. 187-197
-
-
Herskowitz, I.1
-
30
-
-
0027423418
-
Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain
-
Hibi, M., A. Lin, T. Smeal, A. Minden, and M. Karin. 1993. Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain. Genes & Dev. 7: 2135-2148.
-
(1993)
Genes & Dev.
, vol.7
, pp. 2135-2148
-
-
Hibi, M.1
Lin, A.2
Smeal, T.3
Minden, A.4
Karin, M.5
-
31
-
-
0028897113
-
Transcriptional regulation by extracellular signals: Mechanisms and specificity
-
Hill, C.S. and R. Treisman. 1995. Transcriptional regulation by extracellular signals: Mechanisms and specificity. Cell 80: 199-211.
-
(1995)
Cell
, vol.80
, pp. 199-211
-
-
Hill, C.S.1
Treisman, R.2
-
32
-
-
0027509501
-
Phosphorylation and activation of human cdc25-C by cdc2/cyclin B and its involvement in the self-amplification of MPF at mitosis
-
Hoffman, I., P.R. Clarke, M.J. Marcote, E. Karsenti, and G. Draetta. 1993. Phosphorylation and activation of human cdc25-C by cdc2/cyclin B and its involvement in the self-amplification of MPF at mitosis. EMBO J. 12: 53-63.
-
(1993)
EMBO J.
, vol.12
, pp. 53-63
-
-
Hoffman, I.1
Clarke, P.R.2
Marcote, M.J.3
Karsenti, E.4
Draetta, G.5
-
33
-
-
0028022034
-
Activation of the phosphatase activity of human cdc25A by a cdk2-cyclinE dependent phosphorylation at the G1/S transition
-
Hoffman, I., G. Draetta, and E. Karsenti. 1994. Activation of the phosphatase activity of human cdc25A by a cdk2-cyclinE dependent phosphorylation at the G1/S transition. EMBO J. 13: 4302-4310.
-
(1994)
EMBO J.
, vol.13
, pp. 4302-4310
-
-
Hoffman, I.1
Draetta, G.2
Karsenti, E.3
-
34
-
-
0026754369
-
Activation of the MAP kinase pathway by the protein kinase raf
-
Howe, L. R., S.J. Leevers, N. Gomez, S. Nakielny, P. Cohen, and C.J. Marshall. 1992. Activation of the MAP kinase pathway by the protein kinase raf. Cell 71: 335-342.
-
(1992)
Cell
, vol.71
, pp. 335-342
-
-
Howe, L.R.1
Leevers, S.J.2
Gomez, N.3
Nakielny, S.4
Cohen, P.5
Marshall, C.J.6
-
35
-
-
0028838971
-
Protein kinases and phosphatases: The yin and yang of protein phosphorylation and signaling
-
Hunter, T. 1995. Protein kinases and phosphatases: The yin and yang of protein phosphorylation and signaling. Cell 80: 225-236.
-
(1995)
Cell
, vol.80
, pp. 225-236
-
-
Hunter, T.1
-
36
-
-
0027938209
-
Cyclins and cancerII: CyclinD and cdk inhibitors come of age
-
Hunter, T. and J. Pines. 1994. Cyclins and cancerII: CyclinD and cdk inhibitors come of age. Cell 79: 573-582.
-
(1994)
Cell
, vol.79
, pp. 573-582
-
-
Hunter, T.1
Pines, J.2
-
37
-
-
0025800585
-
Phosphorylation of Xenopus cyclins B1 and B2 is not required for cell cycle transitions
-
Izumi, T. and J.L. Maller. 1991. Phosphorylation of Xenopus cyclins B1 and B2 is not required for cell cycle transitions. Mol. Cell Biol. 11: 3860-3867.
-
(1991)
Mol. Cell Biol.
, vol.11
, pp. 3860-3867
-
-
Izumi, T.1
Maller, J.L.2
-
38
-
-
0027075988
-
Periodic changes in phosphorylation of the Xenopus cdc25 phosphatase regulate its activity
-
Izumi, T., D.H. Walker and J.L. Maller. 1992. Periodic changes in phosphorylation of the Xenopus cdc25 phosphatase regulate its activity. Mol. Cell Biol. 3: 1927-1939.
-
(1992)
Mol. Cell Biol.
, vol.3
, pp. 1927-1939
-
-
Izumi, T.1
Walker, D.H.2
Maller, J.L.3
-
39
-
-
0026580389
-
Oscillation of MPF is accompanied by periodic association between cdc25 and cdc2-cyclin B
-
Jessus, C. and D. Beach. 1992. Oscillation of MPF is accompanied by periodic association between cdc25 and cdc2-cyclin B. Cell 68: 323-332.
-
(1992)
Cell
, vol.68
, pp. 323-332
-
-
Jessus, C.1
Beach, D.2
-
40
-
-
0023357739
-
Levels of microtubules during the meiotic maturation of the Xenopus oocyte
-
Jessus, C., C. Thibier, and R. Ozon. 1987. Levels of microtubules during the meiotic maturation of the Xenopus oocyte. J. Cell Sci. 87: 705-712.
-
(1987)
J. Cell Sci.
, vol.87
, pp. 705-712
-
-
Jessus, C.1
Thibier, C.2
Ozon, R.3
-
41
-
-
0028314952
-
Cdc25A is a novel phosphatase functioning early in the cell cycle
-
Jinno, S., K. Suto, A. Nagata, M. Igarashi, Y. Kanaoka, H. Nojima, and H. Okayama. 1994. Cdc25A is a novel phosphatase functioning early in the cell cycle. EMBO J. 13: 1549-1556.
-
(1994)
EMBO J.
, vol.13
, pp. 1549-1556
-
-
Jinno, S.1
Suto, K.2
Nagata, A.3
Igarashi, M.4
Kanaoka, Y.5
Nojima, H.6
Okayama, H.7
-
43
-
-
85035153129
-
Human cyclin E, a new cyclin that interacts with two members of the cdc2 gene family
-
Koff, A., F. Cross, A. Fisher, J. Schumacher, K. Leguallao, M. Phillippe, and J.M. Roberts. 1991. Human cyclin E, a new cyclin that interacts with two members of the cdc2 gene family. Cell 68: 1-20.
-
(1991)
Cell
, vol.68
, pp. 1-20
-
-
Koff, A.1
Cross, F.2
Fisher, A.3
Schumacher, J.4
Leguallao, K.5
Phillippe, M.6
Roberts, J.M.7
-
44
-
-
0026766322
-
Xenopus MAP kinase activator is a serine/threonine/ tyrosine kinase activated by threonine phosphorylation
-
Kosako, H., Y. Gotoh, S. Matsuda, M. Ishikawa, and E. Nishida. 1992. Xenopus MAP kinase activator is a serine/threonine/ tyrosine kinase activated by threonine phosphorylation. EMBO J. 11: 2903-2908.
-
(1992)
EMBO J.
, vol.11
, pp. 2903-2908
-
-
Kosako, H.1
Gotoh, Y.2
Matsuda, S.3
Ishikawa, M.4
Nishida, E.5
-
45
-
-
0026006392
-
Mutations of p34cdc2 phosphorylation sites induce premature mitotic events in HeLa cells: Evidence of a double block to p34cdc2 kinase activation in vertebrates
-
Krek, W. and E.A. Nigg. 1991. Mutations of p34cdc2 phosphorylation sites induce premature mitotic events in HeLa cells: Evidence of a double block to p34cdc2 kinase activation in vertebrates. EMBO J. 10: 3331-3341.
-
(1991)
EMBO J.
, vol.10
, pp. 3331-3341
-
-
Krek, W.1
Nigg, E.A.2
-
46
-
-
0026719599
-
Regulation of the cdc25 protein during the cell cycle in Xenopus extracts
-
Kumagai, A. and W.G. Dunphy. 1992. Regulation of the cdc25 protein during the cell cycle in Xenopus extracts. Cell 70: 139-151.
-
(1992)
Cell
, vol.70
, pp. 139-151
-
-
Kumagai, A.1
Dunphy, W.G.2
-
47
-
-
0026647749
-
Raf-1 activates Map kinase-kinase
-
Kyriakis, J.M., H. App, X.F. Zhang, P. Banerjee, D.L. Brautigan, U.R. Rapp, and J. Avruch. 1992. Raf-1 activates Map kinase-kinase. Nature 358: 417-421.
-
(1992)
Nature
, vol.358
, pp. 417-421
-
-
Kyriakis, J.M.1
App, H.2
Zhang, X.F.3
Banerjee, P.4
Brautigan, D.L.5
Rapp, U.R.6
Avruch, J.7
-
48
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli, U.K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
49
-
-
0028074621
-
Ras-dependent growth factor regulation of MEK kinase in PC12 cells
-
Lange-Carter, C.A. and G.L. Johnson. 1994. Ras-dependent growth factor regulation of MEK kinase in PC12 cells. Science 265: 1458-1461.
-
(1994)
Science
, vol.265
, pp. 1458-1461
-
-
Lange-Carter, C.A.1
Johnson, G.L.2
-
50
-
-
0028272507
-
Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane
-
Leevers, S.J., F.G. Paterson, and C.J. Marshall. 1994. Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane. Nature 369: 411-414.
-
(1994)
Nature
, vol.369
, pp. 411-414
-
-
Leevers, S.J.1
Paterson, F.G.2
Marshall, C.J.3
-
51
-
-
0025850767
-
Isolation of three novel human cyclins by rescue of G1 cyclin (cln) function in yeast
-
Lew, D.J., V. Dulic, and S.I. Reed. 1991. Isolation of three novel human cyclins by rescue of G1 cyclin (cln) function in yeast. Cell 66: 1197-1206
-
(1991)
Cell
, vol.66
, pp. 1197-1206
-
-
Lew, D.J.1
Dulic, V.2
Reed, S.I.3
-
52
-
-
0026035524
-
Mik1 and wee1 cooperate in the inhibitory tyrosine phosphorylation of cdc2
-
Lundgren, K., N. Walworth, R. Booher, M. Dembski, M. Kirschner, and D. Beach. 1991. Mik1 and wee1 cooperate in the inhibitory tyrosine phosphorylation of cdc2. Cell 64: 1111-1122.
-
(1991)
Cell
, vol.64
, pp. 1111-1122
-
-
Lundgren, K.1
Walworth, N.2
Booher, R.3
Dembski, M.4
Kirschner, M.5
Beach, D.6
-
53
-
-
0028872649
-
Specificity of receptor tyrosine kinse signalling: Transient versus sustained extracellular signal-regulated kinase activation
-
Marshall, C.J. 1995. Specificity of receptor tyrosine kinse signalling: Transient versus sustained extracellular signal-regulated kinase activation. Cell 80: 179-185.
-
(1995)
Cell
, vol.80
, pp. 179-185
-
-
Marshall, C.J.1
-
54
-
-
0025819962
-
Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle
-
Matsushime, H., M.F. Roussel, R.A. Ashmun, and C.J. Sherr. 1991. Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle. Cell 65: 701-713.
-
(1991)
Cell
, vol.65
, pp. 701-713
-
-
Matsushime, H.1
Roussel, M.F.2
Ashmun, R.A.3
Sherr, C.J.4
-
55
-
-
0026721068
-
A family of human cdc2-related protein kinases
-
Meyerson, M., G.H. Enders, C.-L. Wu, L.-K. Su, C. Gorka, C. Neilson, E. Harlow, and L.-H. Tsai. 1992. A family of human cdc2-related protein kinases. EMBO J. 11: 2909-2917.
-
(1992)
EMBO J.
, vol.11
, pp. 2909-2917
-
-
Meyerson, M.1
Enders, G.H.2
Wu, C.-L.3
Su, L.-K.4
Gorka, C.5
Neilson, C.6
Harlow, E.7
Tsai, L.-H.8
-
56
-
-
0025987535
-
p80cdc25 mitotic inducer is the tyrosine phosphatase that activates p34cdc2 kinase in fission yeast
-
Millar, J.B., C.H. McGowan, G. Lenaers, R. Jones, and P. Russell. 1991. p80cdc25 mitotic inducer is the tyrosine phosphatase that activates p34cdc2 kinase in fission yeast. EMBO J. 10: 4301-4309.
-
(1991)
EMBO J.
, vol.10
, pp. 4301-4309
-
-
Millar, J.B.1
McGowan, C.H.2
Lenaers, G.3
Jones, R.4
Russell, P.5
-
57
-
-
0028568217
-
Differential activation of ERK and JNK MAP kinases by Raf-1 and MEKK
-
Minden, A., M. McMahon, C. Lange-Carter, B. Derijard, R.J. Davis, G.L. Johnson, and M. Karin. 1994. Differential activation of ERK and JNK MAP kinases by Raf-1 and MEKK. Science 266: 1719-1723.
-
(1994)
Science
, vol.266
, pp. 1719-1723
-
-
Minden, A.1
McMahon, M.2
Lange-Carter, C.3
Derijard, B.4
Davis, R.J.5
Johnson, G.L.6
Karin, M.7
-
58
-
-
0024390591
-
Reversible tyrosine phosphorylation of cdc2: Dephosphorylation accompanies activation during entry into mitosis
-
Moria, A.O., G. Draetta, D. Beach, and J.Y. Wang. 1989. Reversible tyrosine phosphorylation of cdc2: Dephosphorylation accompanies activation during entry into mitosis. Cell 58: 193-203.
-
(1989)
Cell
, vol.58
, pp. 193-203
-
-
Moria, A.O.1
Draetta, G.2
Beach, D.3
Wang, J.Y.4
-
59
-
-
0027190850
-
Raf-1 protein kinase is important for progesterone-induced Xenopus oocyte maturation and acts downstream of mos
-
Muslin, A.J., A.M. MacNicol, and L.T. Williams. 1993. Raf-1 protein kinase is important for progesterone-induced Xenopus oocyte maturation and acts downstream of mos. Mol. Cell. Biol. 13: 4197-4202.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 4197-4202
-
-
Muslin, A.J.1
MacNicol, A.M.2
Williams, L.T.3
-
60
-
-
0026234297
-
An additional homolog of the fission yeast cdc25+ gene occurs in humans and is highly expressed in some cancer cells
-
Nagata, A., M. Igarashi, S. Jinno, K. Suto, and H. Okayama. 1991. An additional homolog of the fission yeast cdc25+ gene occurs in humans and is highly expressed in some cancer cells. New Biol. 3: 959-968.
-
(1991)
New Biol.
, vol.3
, pp. 959-968
-
-
Nagata, A.1
Igarashi, M.2
Jinno, S.3
Suto, K.4
Okayama, H.5
-
61
-
-
0028342664
-
Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen
-
Noda, A., Y. Ning, S.F. Venable, O.M. Pereira-Smith, and J.R. Smith. 1994. Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen. Exp. Cell Res. 211: 90-98.
-
(1994)
Exp. Cell Res.
, vol.211
, pp. 90-98
-
-
Noda, A.1
Ning, Y.2
Venable, S.F.3
Pereira-Smith, O.M.4
Smith, J.R.5
-
62
-
-
0025859464
-
Cyclin promotes the tyrosine phosphorylation of p34cdc2 in a wee1+dependent manner
-
Parker, L.L., S. Atherton-Fessler, M.S. Lee, S. Ogg, J.L. Falk, K.I. Swenson, and H. Piwnica-Worms. 1991. Cyclin promotes the tyrosine phosphorylation of p34cdc2 in a wee1+dependent manner. EMBO J. 10: 1255-1263.
-
(1991)
EMBO J.
, vol.10
, pp. 1255-1263
-
-
Parker, L.L.1
Atherton-Fessler, S.2
Lee, M.S.3
Ogg, S.4
Falk, J.L.5
Swenson, K.I.6
Piwnica-Worms, H.7
-
63
-
-
0026611530
-
p107wee1 is a dual-specificity kinase that phosphorylates p34cdc2 on tyrosine 15
-
Parker, L., S. Atherton-Fessler, and H. Piwnica-Worms. 1992. p107wee1 is a dual-specificity kinase that phosphorylates p34cdc2 on tyrosine 15. Proc. Natl. Acad. Sci. 89: 2917-2921.
-
(1992)
Proc. Natl. Acad. Sci.
, vol.89
, pp. 2917-2921
-
-
Parker, L.1
Atherton-Fessler, S.2
Piwnica-Worms, H.3
-
64
-
-
0028176483
-
Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals
-
Polyak, K., M.H. Lee, H. Erdjument-Bromage, A. Koff, J.M. Roberts, P. Tempst, and J. Massague. 1994a. Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals. Cell 78: 59-66.
-
(1994)
Cell
, vol.78
, pp. 59-66
-
-
Polyak, K.1
Lee, M.H.2
Erdjument-Bromage, H.3
Koff, A.4
Roberts, J.M.5
Tempst, P.6
Massague, J.7
-
65
-
-
0028179669
-
p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest
-
Polyak, K., J.Y. Kato, M.J. Solomon, C.J. Sherr, J. Massague, J.M. Roberts, and A. Koff. 1994b. p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest. Genes & Dev. 8: 9-22.
-
(1994)
Genes & Dev.
, vol.8
, pp. 9-22
-
-
Polyak, K.1
Kato, J.Y.2
Solomon, M.J.3
Sherr, C.J.4
Massague, J.5
Roberts, J.M.6
Koff, A.7
-
66
-
-
0024153822
-
Raf family serine/threonine protein kinases in mitogenic signal transduction
-
Rapp, U.R., G. Heidecker, M. Huleihel, J.L. Cleveland, W.C. Choi, T. Pawson, J.N. Ihle, and W.B. Anderson. 1988. Raf family serine/threonine protein kinases in mitogenic signal transduction. Cold Spring Harbor Symp. Quant. Biol. 53: 173-184.
-
(1988)
Cold Spring Harbor Symp. Quant. Biol.
, vol.53
, pp. 173-184
-
-
Rapp, U.R.1
Heidecker, G.2
Huleihel, M.3
Cleveland, J.L.4
Choi, W.C.5
Pawson, T.6
Ihle, J.N.7
Anderson, W.B.8
-
67
-
-
0028074316
-
Phosphatidylinositol-3-OH kinase as a direct target of Ras
-
Rodriguez-Viciana, P., P.H. Warne, R. Dhand, B. Vanhaesebroeck, I. Gout, M.J. Fry, M.D. Waterfield, and J. Downward. 1994. Phosphatidylinositol-3-OH kinase as a direct target of Ras. Nature 370: 527-532.
-
(1994)
Nature
, vol.370
, pp. 527-532
-
-
Rodriguez-Viciana, P.1
Warne, P.H.2
Dhand, R.3
Vanhaesebroeck, B.4
Gout, I.5
Fry, M.J.6
Waterfield, M.D.7
Downward, J.8
-
68
-
-
0018294520
-
Synthesis of labile, serum-dependent protein in early G1 controls animal cell growth
-
Rossow, P.W., V.G.H. Riddle, and A.B. Pardee. 1979. Synthesis of labile, serum-dependent protein in early G1 controls animal cell growth. Proc. Natl. Acad. Sci. 76: 4446-4450.
-
(1979)
Proc. Natl. Acad. Sci.
, vol.76
, pp. 4446-4450
-
-
Rossow, P.W.1
Riddle, V.G.H.2
Pardee, A.B.3
-
69
-
-
0022462146
-
cdc25+ functions as an inducer in the mitotic control of fission yeast
-
Russell, P. and P. Nurse. 1986. cdc25+ functions as an inducer in the mitotic control of fission yeast. Cell 45: 145-153.
-
(1986)
Cell
, vol.45
, pp. 145-153
-
-
Russell, P.1
Nurse, P.2
-
70
-
-
0023662312
-
Negative regulation of mitosis by wee1+, a gene encoding a protein kinase homolog
-
_. 1987. Negative regulation of mitosis by wee1+, a gene encoding a protein kinase homolog. Cell 49: 559-567.
-
(1987)
Cell
, vol.49
, pp. 559-567
-
-
-
71
-
-
0025324692
-
Human homolog of fission yeast cdc25 mitotic inducer is predominantly expressed in G2
-
Sadhu, K., S.I. Reed, H. Richardson, and P. Russell. 1990. Human homolog of fission yeast cdc25 mitotic inducer is predominantly expressed in G2. Proc. Natl. Acad. Sci. 87: 5139-5143.
-
(1990)
Proc. Natl. Acad. Sci.
, vol.87
, pp. 5139-5143
-
-
Sadhu, K.1
Reed, S.I.2
Richardson, H.3
Russell, P.4
-
73
-
-
0028558986
-
Role of SAPK/ ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun
-
Sanchez, I., R.T. Hughes, B.J. Mayer, K. Yee, J.R. Woodgett, J. Avruch, J.M. Kyriakis, and L.I. Zon. 1994. Role of SAPK/ ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun. Nature 372: 794-798.
-
(1994)
Nature
, vol.372
, pp. 794-798
-
-
Sanchez, I.1
Hughes, R.T.2
Mayer, B.J.3
Yee, K.4
Woodgett, J.R.5
Avruch, J.6
Kyriakis, J.M.7
Zon, L.I.8
-
74
-
-
0027769876
-
A new regulatory motif in cell cycle control causing specific inhibition of cyclin D/CDK4
-
Serrano, M., G. Hannon, and D. Beach. 1993. A new regulatory motif in cell cycle control causing specific inhibition of cyclin D/CDK4. Nature 366: 704-707.
-
(1993)
Nature
, vol.366
, pp. 704-707
-
-
Serrano, M.1
Hannon, G.2
Beach, D.3
-
75
-
-
0028171292
-
G1-phase progression: Cycling on cue
-
Sherr, C.J. 1994. G1-phase progression: cycling on cue. Cell 79: 817-825.
-
(1994)
Cell
, vol.79
, pp. 817-825
-
-
Sherr, C.J.1
-
76
-
-
0027007963
-
The role of phosphorylation in p34cdk2 activation: Identification of an activating kinase
-
Solomon, M., T. Lee, and M. Kirschner. 1992. The role of phosphorylation in p34cdk2 activation: Identification of an activating kinase. Mol. Biol. Cell 3: 13-27.
-
(1992)
Mol. Biol. Cell
, vol.3
, pp. 13-27
-
-
Solomon, M.1
Lee, T.2
Kirschner, M.3
-
77
-
-
0026336517
-
Dominant inhibitory Ras mutants demonstrate the requirement for Ras activity in the action of tyrosine kinase oncogenes
-
Stacey, D.W., M. Roudebush, R. Day, S.D. Mosser, J.B. Gibbs, and L.A. Feig. 1991. Dominant inhibitory Ras mutants demonstrate the requirement for Ras activity in the action of tyrosine kinase oncogenes. Oncogene 6: 2297-2304.
-
(1991)
Oncogene
, vol.6
, pp. 2297-2304
-
-
Stacey, D.W.1
Roudebush, M.2
Day, R.3
Mosser, S.D.4
Gibbs, J.B.5
Feig, L.A.6
-
78
-
-
0024545162
-
Definition of the human raf amino-terminal regulatory region by deletion mutagenesis
-
Stanton, V.P. Jr., D.W. Nichols, A.P. Laudano, and G.M. Cooper. 1989. Definition of the human raf amino-terminal regulatory region by deletion mutagenesis. Mol. Cell Biol. 9: 639-647.
-
(1989)
Mol. Cell Biol.
, vol.9
, pp. 639-647
-
-
Stanton Jr., V.P.1
Nichols, D.W.2
Laudano, A.P.3
Cooper, G.M.4
-
79
-
-
0028241533
-
Activation of Raf as a result of recruitment to the plasma membrane
-
Stokoe, D., S.G. Macdonald, K. Cadwallader, M. Symons, and J.F. Hancock. 1994. Activation of Raf as a result of recruitment to the plasma membrane. Science 264: 1463-1467.
-
(1994)
Science
, vol.264
, pp. 1463-1467
-
-
Stokoe, D.1
Macdonald, S.G.2
Cadwallader, K.3
Symons, M.4
Hancock, J.F.5
-
80
-
-
0025922083
-
Dephosphorylation and activation of a p34cdc2 cyclin-B complex in vitro by human cdc25 protein
-
Strausfeld, U., J.C. Labbe, D. Fesquet, J.C. Cavadore, A. Picard, K. Sadhu, P. Russell, and M. Doree. 1991. Dephosphorylation and activation of a p34cdc2 cyclin-B complex in vitro by human cdc25 protein. Nature 351: 242-245.
-
(1991)
Nature
, vol.351
, pp. 242-245
-
-
Strausfeld, U.1
Labbe, J.C.2
Fesquet, D.3
Cavadore, J.C.4
Picard, A.5
Sadhu, K.6
Russell, P.7
Doree, M.8
-
81
-
-
0022915860
-
The clam embryo protein cyclin A induces entry into M phase and the resumption of meiosis in Xenopus oocytes
-
Swenson, K.I., K.M. Farrell, and J.V. Ruderman. 1986. The clam embryo protein cyclin A induces entry into M phase and the resumption of meiosis in Xenopus oocytes. Cell 47: 861-870.
-
(1986)
Cell
, vol.47
, pp. 861-870
-
-
Swenson, K.I.1
Farrell, K.M.2
Ruderman, J.V.3
-
82
-
-
0026534571
-
Ras is essential for nerve growth factor-and phorbol ester-induced tyrosine phosphorylation of MAP kinases
-
Thomas, S.M., M. DeMarco, G. D'Arcangelo, S. Halegoua, and J.S. Brugge. 1992. Ras is essential for nerve growth factor-and phorbol ester-induced tyrosine phosphorylation of MAP kinases. Cell 68: 1031-1040.
-
(1992)
Cell
, vol.68
, pp. 1031-1040
-
-
Thomas, S.M.1
Demarco, M.2
D'Arcangelo, G.3
Halegoua, S.4
Brugge, J.S.5
-
83
-
-
0028363519
-
p27, a novel inhibitor of G1 cyclin-cdk protein kinase activity, is related to p21
-
Toyoshima, H. and T. Hunter. 1994. p27, a novel inhibitor of G1 cyclin-cdk protein kinase activity, is related to p21. Cell 78: 67-74.
-
(1994)
Cell
, vol.78
, pp. 67-74
-
-
Toyoshima, H.1
Hunter, T.2
-
84
-
-
0027527919
-
Specific association of activated MAP kinase kinase kinase (Raf) with the plasma membranes of ras-transformed retinal cells
-
Traverse, S., P. Cohen, H. Paterson, C. Marshall, U. Rapp, and R.J. Grand. 1993. Specific association of activated MAP kinase kinase kinase (Raf) with the plasma membranes of ras-transformed retinal cells. Oncogene 8: 3175-3181.
-
(1993)
Oncogene
, vol.8
, pp. 3175-3181
-
-
Traverse, S.1
Cohen, P.2
Paterson, H.3
Marshall, C.4
Rapp, U.5
Grand, R.J.6
-
85
-
-
0027161398
-
Complex formation between RAS and RAF and other protein kinases
-
van Aelst, L., M. Barr, S. Marcus, A. Polverino, and M. Wigler. 1993. Complex formation between RAS and RAF and other protein kinases. Proc. Natl. Acad. Sci. 90: 6213-6217.
-
(1993)
Proc. Natl. Acad. Sci.
, vol.90
, pp. 6213-6217
-
-
Aelst, L.1
Barr, M.2
Marcus, S.3
Polverino, A.4
Wigler, M.5
-
86
-
-
0028227245
-
The native structure of the activated Raf protein kinase is a membrane-bound multi-subunit complex
-
Wartmann, M. and R.J. Davis. 1994. The native structure of the activated Raf protein kinase is a membrane-bound multi-subunit complex. J. Biol. Chem. 269: 6695-6701.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 6695-6701
-
-
Wartmann, M.1
Davis, R.J.2
-
87
-
-
0026611532
-
src are required, but neither alone is sufficient, to activate the Raf-1 kinase
-
src are required, but neither alone is sufficient, to activate the Raf-1 kinase. Proc. Natl. Acad. Sci. 89: 2922-2926.
-
(1992)
Proc. Natl. Acad. Sci.
, vol.89
, pp. 2922-2926
-
-
Williams, N.G.1
Roberts, T.M.2
Li, P.3
-
88
-
-
0027335883
-
Raf-1 and p21v-ras cooperate in the activation of mitogen-activated protein kinase
-
Williams, N.G., H. Paradis, S. Agarwal, D.L. Charest, S.L. Pelech, and T.M. Roberts. 1993. Raf-1 and p21v-ras cooperate in the activation of mitogen-activated protein kinase. Proc. Natl. Acad. Sci. 90: 5772-5776.
-
(1993)
Proc. Natl. Acad. Sci.
, vol.90
, pp. 5772-5776
-
-
Williams, N.G.1
Paradis, H.2
Agarwal, S.3
Charest, D.L.4
Pelech, S.L.5
Roberts, T.M.6
-
89
-
-
0026699554
-
Growth-regulated expression of D-type cyclin genes in human diploid fibroblasts
-
Won, K.A., Y. Xiong, D. Beach, and M.Z. Gilman. 1992. Growth-regulated expression of D-type cyclin genes in human diploid fibroblasts. Proc. Natl. Acad. Sci. 89: 9910-9914.
-
(1992)
Proc. Natl. Acad. Sci.
, vol.89
, pp. 9910-9914
-
-
Won, K.A.1
Xiong, Y.2
Beach, D.3
Gilman, M.Z.4
-
90
-
-
0026523559
-
Ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK
-
Wood, K.W., C. Sarnecki, T.M. Roberts, and J. Blenis. 1992. Ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK. Cell 68: 1041-1050.
-
(1992)
Cell
, vol.68
, pp. 1041-1050
-
-
Wood, K.W.1
Sarnecki, C.2
Roberts, T.M.3
Blenis, J.4
-
91
-
-
0025824253
-
Human D-type cyclin
-
Xiong, Y., T. Connolly, B. Futcher, and D. Beach. 1991. Human D-type cyclin. Cell 65: 691-699.
-
(1991)
Cell
, vol.65
, pp. 691-699
-
-
Xiong, Y.1
Connolly, T.2
Futcher, B.3
Beach, D.4
-
92
-
-
0027717617
-
p21 is a universal inhibitor of cyclin kinases
-
Xiong, Y., G. Hannon, H. Zhang, D. Casso, R. Kobayashi, and D. Beach. 1993. p21 is a universal inhibitor of cyclin kinases. Nature 366: 701-704.
-
(1993)
Nature
, vol.366
, pp. 701-704
-
-
Xiong, Y.1
Hannon, G.2
Zhang, H.3
Casso, D.4
Kobayashi, R.5
Beach, D.6
-
93
-
-
0028670788
-
Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator, SEK1
-
Yan, M., T. Dai, J.C. Deak, J.M. Kyriakis, L.I. Zon, J.R. Woodgett, and D.J. Templeton. 1994. Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator, SEK1. Nature 370: 798-801.
-
(1994)
Nature
, vol.370
, pp. 798-801
-
-
Yan, M.1
Dai, T.2
Deak, J.C.3
Kyriakis, J.M.4
Zon, L.I.5
Woodgett, J.R.6
Templeton, D.J.7
|