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Volumn 9, Issue 9, 1995, Pages 1046-1058

Raf1 interaction with Cdc25 phosphatase ties mitogenic signal transduction to cell cycle activation

Author keywords

Cdc25 phosphatase; cell cycle activation; Raf 1; Ras; signal transduction

Indexed keywords

CYCLIN DEPENDENT KINASE; PHOSPHATASE; RAS PROTEIN; THREONINE; TYROSINE;

EID: 0029042689     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.9.9.1046     Document Type: Article
Times cited : (230)

References (93)
  • 1
    • 0025832605 scopus 로고
    • Multiple components in an epidermal growth factor-stimulated protein kinase cascade. in vitro activation of a myelin basic protein/microtubule-associated protein 2 kinase
    • Ahn, N.G., R. Seger, R.L. Bratlien, C.D. Diltz, N.K. Tonks, and E.G. Krebs. 1991. Multiple components in an epidermal growth factor-stimulated protein kinase cascade. In vitro activation of a myelin basic protein/microtubule-associated protein 2 kinase. J. Biol. Chem. 266: 4220-4227.
    • (1991) J. Biol. Chem. , vol.266 , pp. 4220-4227
    • Ahn, N.G.1    Seger, R.2    Bratlien, R.L.3    Diltz, C.D.4    Tonks, N.K.5    Krebs, E.G.6
  • 2
    • 0028228616 scopus 로고
    • Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells
    • Cowley, S., H. Paterson, P. Kemp, and C.J. Marshall. 1994. Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells. Cell 77: 841-852.
    • (1994) Cell , vol.77 , pp. 841-852
    • Cowley, S.1    Paterson, H.2    Kemp, P.3    Marshall, C.J.4
  • 3
    • 0026641090 scopus 로고
    • Activation of mitogen-activated protein kinase kinase by v-Raf in NIH 3T3 cells and in vitro
    • Dent, P., W. Haser, T.A.J. Haystead, L.A. Vincent, T.M. Robers, and T.W. Sturgill. 1992. Activation of mitogen-activated protein kinase kinase by v-Raf in NIH 3T3 cells and in vitro. Science 257: 1404-1407.
    • (1992) Science , vol.257 , pp. 1404-1407
    • Dent, P.1    Haser, W.2    Haystead, T.A.J.3    Vincent, L.A.4    Robers, T.M.5    Sturgill, T.W.6
  • 4
    • 0024267140 scopus 로고
    • Human cdc2 protein kinase is a major cell-cycle regulated tyrosine kinase substrate
    • Draetta, G., H. Piwnica-Worms, D. Morrison, B. Druker, T. Roberts, and D. Beach. 1988. Human cdc2 protein kinase is a major cell-cycle regulated tyrosine kinase substrate. Nature 336: 738-744.
    • (1988) Nature , vol.336 , pp. 738-744
    • Draetta, G.1    Piwnica-Worms, H.2    Morrison, D.3    Druker, B.4    Roberts, T.5    Beach, D.6
  • 5
    • 0028220204 scopus 로고
    • p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest
    • Dulic, V., W.K. Kaufmann, S.J. Wilson, T.D. Tlsty, E. Lees, J.W. Harper, S.J. Elledge, and S.I. Reed. 1994. p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest. Cell 76: 1013-1023.
    • (1994) Cell , vol.76 , pp. 1013-1023
    • Dulic, V.1    Kaufmann, W.K.2    Wilson, S.J.3    Tlsty, T.D.4    Lees, E.5    Harper, J.W.6    Elledge, S.J.7    Reed, S.I.8
  • 6
    • 0025938467 scopus 로고
    • The cdc25 protein contains an intrinsic phosphatase activity
    • Dunphy, W.G. and A. Kumagai. 1991. The cdc25 protein contains an intrinsic phosphatase activity. Cell 67: 189-196.
    • (1991) Cell , vol.67 , pp. 189-196
    • Dunphy, W.G.1    Kumagai, A.2
  • 7
    • 0024395110 scopus 로고
    • Fission yeast p13 blocks mitotic activation and tyrosine dephosphorylation of the Xenopus cdc2 protein kinase
    • Dunphy, W.G. and J.W. Newport. 1989. Fission yeast p13 blocks mitotic activation and tyrosine dephosphorylation of the Xenopus cdc2 protein kinase. Cell 58: 181-431.
    • (1989) Cell , vol.58 , pp. 181-431
    • Dunphy, W.G.1    Newport, J.W.2
  • 9
    • 0020961333 scopus 로고
    • Cyclin: A protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage division
    • Evans, T., E.T. Rosenthal, J. Youngblom, D. Distel, and T. Hunt. 1983. Cyclin: A protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage division. Cell 33: 389-396.
    • (1983) Cell , vol.33 , pp. 389-396
    • Evans, T.1    Rosenthal, E.T.2    Youngblom, J.3    Distel, D.4    Hunt, T.5
  • 10
    • 0027184473 scopus 로고
    • Requirement for Raf and MAP kinase function during the meiotic maturation of Xenopus oocytes
    • Fabian, J.R., D.K. Morrison, and I.O. Daar. 1993a. Requirement for Raf and MAP kinase function during the meiotic maturation of Xenopus oocytes. J. Cell Biol. 122: 645-652.
    • (1993) J. Cell Biol. , vol.122 , pp. 645-652
    • Fabian, J.R.1    Morrison, D.K.2    Daar, I.O.3
  • 11
    • 0027364980 scopus 로고
    • Critical tyrosine residues regulate the enzymatic and biological activity of Raf-1 kinase
    • Fabian, J.R., I.O. Daar, and D.K. Morrison. 1993b. Critical tyrosine residues regulate the enzymatic and biological activity of Raf-1 kinase. Mol. Cell Biol. 13: 7170-7173.
    • (1993) Mol. Cell Biol. , vol.13 , pp. 7170-7173
    • Fabian, J.R.1    Daar, I.O.2    Morrison, D.K.3
  • 12
    • 0025924328 scopus 로고
    • Fission yeast p107wee1 mitotic inhibitor is a tyrosine/serine kinase
    • Featherstone, C. and P. Russell. 1991. Fission yeast p107wee1 mitotic inhibitor is a tyrosine/serine kinase. Nature 349: 808-811.
    • (1991) Nature , vol.349 , pp. 808-811
    • Featherstone, C.1    Russell, P.2
  • 13
    • 0028073606 scopus 로고
    • Binding of 14-3-3 proteins to the protein kinase Raf and effects on its activation
    • Freed, E., M. Symons, S.G. Macdonald, F. McCormick, and R. Ruggieri. 1994. Binding of 14-3-3 proteins to the protein kinase Raf and effects on its activation. Science 265: 1713-1716.
    • (1994) Science , vol.265 , pp. 1713-1716
    • Freed, E.1    Symons, M.2    Macdonald, S.G.3    McCormick, F.4    Ruggieri, R.5
  • 15
    • 0026319225 scopus 로고
    • Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: Evidence for multiple roles of mitotic cyclins
    • Galaktionov, K. and D. Beach. 1991. Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: Evidence for multiple roles of mitotic cyclins. Cell 67: 1181-1194.
    • (1991) Cell , vol.67 , pp. 1181-1194
    • Galaktionov, K.1    Beach, D.2
  • 16
    • 0024976415 scopus 로고
    • Dephosphorylation and activation of Xenopus p34cdc2 protein kinase during the cell cycle
    • Gautier, J., T. Matsukawa, P. Nurse, and J. Maller. 1989. Dephosphorylation and activation of Xenopus p34cdc2 protein kinase during the cell cycle. Nature 339: 626-629.
    • (1989) Nature , vol.339 , pp. 626-629
    • Gautier, J.1    Matsukawa, T.2    Nurse, P.3    Maller, J.4
  • 17
    • 0025936510 scopus 로고
    • Cdc25 is a specific tyrosine phosphatase that directly activates p34cdc2
    • Gautier, J., M. Solomon, R. Booher, J. Bazan, and M. Kirshner. 1991. Cdc25 is a specific tyrosine phosphatase that directly activates p34cdc2. Cell 67: 197-211.
    • (1991) Cell , vol.67 , pp. 197-211
    • Gautier, J.1    Solomon, M.2    Booher, R.3    Bazan, J.4    Kirshner, M.5
  • 18
    • 0007713485 scopus 로고
    • Dissection of the protein kinase cascade by which nerve growth factor activates MAP kinases
    • Gomez, N. and P. Cohen. 1991. Dissection of the protein kinase cascade by which nerve growth factor activates MAP kinases. Nature 351: 69-72.
    • (1991) Nature , vol.351 , pp. 69-72
    • Gomez, N.1    Cohen, P.2
  • 19
    • 0024959919 scopus 로고
    • Tyrosine phosphorylation of the fission cdc2+ protein kinase regulates entry into mitosis
    • Gould, K. and P. Nurse. 1989. Tyrosine phosphorylation of the fission cdc2+ protein kinase regulates entry into mitosis. Nature 342: 39-45.
    • (1989) Nature , vol.342 , pp. 39-45
    • Gould, K.1    Nurse, P.2
  • 20
    • 0026713875 scopus 로고
    • Cell cycle regulation of cdk2 activity by phosphorylation of Thr160 and Tyr15
    • Gu, Y., J. Rosenblatt, and D.O. Morgan. 1992. Cell cycle regulation of cdk2 activity by phosphorylation of Thr160 and Tyr15. EMBO J. 11: 3995-4005.
    • (1992) EMBO J. , vol.11 , pp. 3995-4005
    • Gu, Y.1    Rosenblatt, J.2    Morgan, D.O.3
  • 21
    • 0027731971 scopus 로고
    • Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit
    • Gu, Y., C.W. Turck, and D.O. Morgan. 1993. Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit. Nature 366: 707-710.
    • (1993) Nature , vol.366 , pp. 707-710
    • Gu, Y.1    Turck, C.W.2    Morgan, D.O.3
  • 22
    • 0028582034 scopus 로고
    • Growth suppression by p18, a p16ink4/MTS1-and p14 ink4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function
    • Guan, K.-L., C.W. Jenkins, Y. Li, M. Nichols, X. Wu, C. O'Keefe, A.G. Matera, and Y. Xiong. 1994. Growth suppression by p18, a p16ink4/MTS1-and p14 ink4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function. Genes & Development. 8: 2939-2952.
    • (1994) Genes & Development , vol.8 , pp. 2939-2952
    • Guan, K.-L.1    Jenkins, C.W.2    Li, Y.3    Nichols, M.4    Wu, X.5    O'Keefe, C.6    Matera, A.G.7    Xiong, Y.8
  • 24
    • 0028168242 scopus 로고
    • p15INK4B is a potential effector of TGF-β mediated cell cycle arrest
    • Hannon, G.J. and D. Beach. 1994. p15INK4B is a potential effector of TGF-β mediated cell cycle arrest. Nature 371: 257-261.
    • (1994) Nature , vol.371 , pp. 257-261
    • Hannon, G.J.1    Beach, D.2
  • 25
    • 0027496935 scopus 로고
    • The p21 cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
    • Harper, J.W., G.R. Adami, N. Wei, J. Keyomarsi, and S.J. Elledge. 1993. The p21 cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 75: 805-816.
    • (1993) Cell , vol.75 , pp. 805-816
    • Harper, J.W.1    Adami, G.R.2    Wei, N.3    Keyomarsi, J.4    Elledge, S.J.5
  • 26
    • 0027967944 scopus 로고
    • Rules to replicate by
    • Heichman, K.A. and J. Roberts. 1994. Rules to replicate by. Cell 79: 557-562.
    • (1994) Cell , vol.79 , pp. 557-562
    • Heichman, K.A.1    Roberts, J.2
  • 29
    • 0028985079 scopus 로고
    • MAP kinase pathways in yeast: For mating and more
    • Herskowitz, I. 1995. MAP kinase pathways in yeast: For mating and more. Cell 80: 187-197.
    • (1995) Cell , vol.80 , pp. 187-197
    • Herskowitz, I.1
  • 30
    • 0027423418 scopus 로고
    • Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain
    • Hibi, M., A. Lin, T. Smeal, A. Minden, and M. Karin. 1993. Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain. Genes & Dev. 7: 2135-2148.
    • (1993) Genes & Dev. , vol.7 , pp. 2135-2148
    • Hibi, M.1    Lin, A.2    Smeal, T.3    Minden, A.4    Karin, M.5
  • 31
    • 0028897113 scopus 로고
    • Transcriptional regulation by extracellular signals: Mechanisms and specificity
    • Hill, C.S. and R. Treisman. 1995. Transcriptional regulation by extracellular signals: Mechanisms and specificity. Cell 80: 199-211.
    • (1995) Cell , vol.80 , pp. 199-211
    • Hill, C.S.1    Treisman, R.2
  • 32
    • 0027509501 scopus 로고
    • Phosphorylation and activation of human cdc25-C by cdc2/cyclin B and its involvement in the self-amplification of MPF at mitosis
    • Hoffman, I., P.R. Clarke, M.J. Marcote, E. Karsenti, and G. Draetta. 1993. Phosphorylation and activation of human cdc25-C by cdc2/cyclin B and its involvement in the self-amplification of MPF at mitosis. EMBO J. 12: 53-63.
    • (1993) EMBO J. , vol.12 , pp. 53-63
    • Hoffman, I.1    Clarke, P.R.2    Marcote, M.J.3    Karsenti, E.4    Draetta, G.5
  • 33
    • 0028022034 scopus 로고
    • Activation of the phosphatase activity of human cdc25A by a cdk2-cyclinE dependent phosphorylation at the G1/S transition
    • Hoffman, I., G. Draetta, and E. Karsenti. 1994. Activation of the phosphatase activity of human cdc25A by a cdk2-cyclinE dependent phosphorylation at the G1/S transition. EMBO J. 13: 4302-4310.
    • (1994) EMBO J. , vol.13 , pp. 4302-4310
    • Hoffman, I.1    Draetta, G.2    Karsenti, E.3
  • 35
    • 0028838971 scopus 로고
    • Protein kinases and phosphatases: The yin and yang of protein phosphorylation and signaling
    • Hunter, T. 1995. Protein kinases and phosphatases: The yin and yang of protein phosphorylation and signaling. Cell 80: 225-236.
    • (1995) Cell , vol.80 , pp. 225-236
    • Hunter, T.1
  • 36
    • 0027938209 scopus 로고
    • Cyclins and cancerII: CyclinD and cdk inhibitors come of age
    • Hunter, T. and J. Pines. 1994. Cyclins and cancerII: CyclinD and cdk inhibitors come of age. Cell 79: 573-582.
    • (1994) Cell , vol.79 , pp. 573-582
    • Hunter, T.1    Pines, J.2
  • 37
    • 0025800585 scopus 로고
    • Phosphorylation of Xenopus cyclins B1 and B2 is not required for cell cycle transitions
    • Izumi, T. and J.L. Maller. 1991. Phosphorylation of Xenopus cyclins B1 and B2 is not required for cell cycle transitions. Mol. Cell Biol. 11: 3860-3867.
    • (1991) Mol. Cell Biol. , vol.11 , pp. 3860-3867
    • Izumi, T.1    Maller, J.L.2
  • 38
    • 0027075988 scopus 로고
    • Periodic changes in phosphorylation of the Xenopus cdc25 phosphatase regulate its activity
    • Izumi, T., D.H. Walker and J.L. Maller. 1992. Periodic changes in phosphorylation of the Xenopus cdc25 phosphatase regulate its activity. Mol. Cell Biol. 3: 1927-1939.
    • (1992) Mol. Cell Biol. , vol.3 , pp. 1927-1939
    • Izumi, T.1    Walker, D.H.2    Maller, J.L.3
  • 39
    • 0026580389 scopus 로고
    • Oscillation of MPF is accompanied by periodic association between cdc25 and cdc2-cyclin B
    • Jessus, C. and D. Beach. 1992. Oscillation of MPF is accompanied by periodic association between cdc25 and cdc2-cyclin B. Cell 68: 323-332.
    • (1992) Cell , vol.68 , pp. 323-332
    • Jessus, C.1    Beach, D.2
  • 40
    • 0023357739 scopus 로고
    • Levels of microtubules during the meiotic maturation of the Xenopus oocyte
    • Jessus, C., C. Thibier, and R. Ozon. 1987. Levels of microtubules during the meiotic maturation of the Xenopus oocyte. J. Cell Sci. 87: 705-712.
    • (1987) J. Cell Sci. , vol.87 , pp. 705-712
    • Jessus, C.1    Thibier, C.2    Ozon, R.3
  • 44
    • 0026766322 scopus 로고
    • Xenopus MAP kinase activator is a serine/threonine/ tyrosine kinase activated by threonine phosphorylation
    • Kosako, H., Y. Gotoh, S. Matsuda, M. Ishikawa, and E. Nishida. 1992. Xenopus MAP kinase activator is a serine/threonine/ tyrosine kinase activated by threonine phosphorylation. EMBO J. 11: 2903-2908.
    • (1992) EMBO J. , vol.11 , pp. 2903-2908
    • Kosako, H.1    Gotoh, Y.2    Matsuda, S.3    Ishikawa, M.4    Nishida, E.5
  • 45
    • 0026006392 scopus 로고
    • Mutations of p34cdc2 phosphorylation sites induce premature mitotic events in HeLa cells: Evidence of a double block to p34cdc2 kinase activation in vertebrates
    • Krek, W. and E.A. Nigg. 1991. Mutations of p34cdc2 phosphorylation sites induce premature mitotic events in HeLa cells: Evidence of a double block to p34cdc2 kinase activation in vertebrates. EMBO J. 10: 3331-3341.
    • (1991) EMBO J. , vol.10 , pp. 3331-3341
    • Krek, W.1    Nigg, E.A.2
  • 46
    • 0026719599 scopus 로고
    • Regulation of the cdc25 protein during the cell cycle in Xenopus extracts
    • Kumagai, A. and W.G. Dunphy. 1992. Regulation of the cdc25 protein during the cell cycle in Xenopus extracts. Cell 70: 139-151.
    • (1992) Cell , vol.70 , pp. 139-151
    • Kumagai, A.1    Dunphy, W.G.2
  • 48
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, U.K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 49
    • 0028074621 scopus 로고
    • Ras-dependent growth factor regulation of MEK kinase in PC12 cells
    • Lange-Carter, C.A. and G.L. Johnson. 1994. Ras-dependent growth factor regulation of MEK kinase in PC12 cells. Science 265: 1458-1461.
    • (1994) Science , vol.265 , pp. 1458-1461
    • Lange-Carter, C.A.1    Johnson, G.L.2
  • 50
    • 0028272507 scopus 로고
    • Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane
    • Leevers, S.J., F.G. Paterson, and C.J. Marshall. 1994. Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane. Nature 369: 411-414.
    • (1994) Nature , vol.369 , pp. 411-414
    • Leevers, S.J.1    Paterson, F.G.2    Marshall, C.J.3
  • 51
    • 0025850767 scopus 로고
    • Isolation of three novel human cyclins by rescue of G1 cyclin (cln) function in yeast
    • Lew, D.J., V. Dulic, and S.I. Reed. 1991. Isolation of three novel human cyclins by rescue of G1 cyclin (cln) function in yeast. Cell 66: 1197-1206
    • (1991) Cell , vol.66 , pp. 1197-1206
    • Lew, D.J.1    Dulic, V.2    Reed, S.I.3
  • 52
    • 0026035524 scopus 로고
    • Mik1 and wee1 cooperate in the inhibitory tyrosine phosphorylation of cdc2
    • Lundgren, K., N. Walworth, R. Booher, M. Dembski, M. Kirschner, and D. Beach. 1991. Mik1 and wee1 cooperate in the inhibitory tyrosine phosphorylation of cdc2. Cell 64: 1111-1122.
    • (1991) Cell , vol.64 , pp. 1111-1122
    • Lundgren, K.1    Walworth, N.2    Booher, R.3    Dembski, M.4    Kirschner, M.5    Beach, D.6
  • 53
    • 0028872649 scopus 로고
    • Specificity of receptor tyrosine kinse signalling: Transient versus sustained extracellular signal-regulated kinase activation
    • Marshall, C.J. 1995. Specificity of receptor tyrosine kinse signalling: Transient versus sustained extracellular signal-regulated kinase activation. Cell 80: 179-185.
    • (1995) Cell , vol.80 , pp. 179-185
    • Marshall, C.J.1
  • 54
    • 0025819962 scopus 로고
    • Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle
    • Matsushime, H., M.F. Roussel, R.A. Ashmun, and C.J. Sherr. 1991. Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle. Cell 65: 701-713.
    • (1991) Cell , vol.65 , pp. 701-713
    • Matsushime, H.1    Roussel, M.F.2    Ashmun, R.A.3    Sherr, C.J.4
  • 56
    • 0025987535 scopus 로고
    • p80cdc25 mitotic inducer is the tyrosine phosphatase that activates p34cdc2 kinase in fission yeast
    • Millar, J.B., C.H. McGowan, G. Lenaers, R. Jones, and P. Russell. 1991. p80cdc25 mitotic inducer is the tyrosine phosphatase that activates p34cdc2 kinase in fission yeast. EMBO J. 10: 4301-4309.
    • (1991) EMBO J. , vol.10 , pp. 4301-4309
    • Millar, J.B.1    McGowan, C.H.2    Lenaers, G.3    Jones, R.4    Russell, P.5
  • 58
    • 0024390591 scopus 로고
    • Reversible tyrosine phosphorylation of cdc2: Dephosphorylation accompanies activation during entry into mitosis
    • Moria, A.O., G. Draetta, D. Beach, and J.Y. Wang. 1989. Reversible tyrosine phosphorylation of cdc2: Dephosphorylation accompanies activation during entry into mitosis. Cell 58: 193-203.
    • (1989) Cell , vol.58 , pp. 193-203
    • Moria, A.O.1    Draetta, G.2    Beach, D.3    Wang, J.Y.4
  • 59
    • 0027190850 scopus 로고
    • Raf-1 protein kinase is important for progesterone-induced Xenopus oocyte maturation and acts downstream of mos
    • Muslin, A.J., A.M. MacNicol, and L.T. Williams. 1993. Raf-1 protein kinase is important for progesterone-induced Xenopus oocyte maturation and acts downstream of mos. Mol. Cell. Biol. 13: 4197-4202.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 4197-4202
    • Muslin, A.J.1    MacNicol, A.M.2    Williams, L.T.3
  • 60
    • 0026234297 scopus 로고
    • An additional homolog of the fission yeast cdc25+ gene occurs in humans and is highly expressed in some cancer cells
    • Nagata, A., M. Igarashi, S. Jinno, K. Suto, and H. Okayama. 1991. An additional homolog of the fission yeast cdc25+ gene occurs in humans and is highly expressed in some cancer cells. New Biol. 3: 959-968.
    • (1991) New Biol. , vol.3 , pp. 959-968
    • Nagata, A.1    Igarashi, M.2    Jinno, S.3    Suto, K.4    Okayama, H.5
  • 61
    • 0028342664 scopus 로고
    • Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen
    • Noda, A., Y. Ning, S.F. Venable, O.M. Pereira-Smith, and J.R. Smith. 1994. Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen. Exp. Cell Res. 211: 90-98.
    • (1994) Exp. Cell Res. , vol.211 , pp. 90-98
    • Noda, A.1    Ning, Y.2    Venable, S.F.3    Pereira-Smith, O.M.4    Smith, J.R.5
  • 63
    • 0026611530 scopus 로고
    • p107wee1 is a dual-specificity kinase that phosphorylates p34cdc2 on tyrosine 15
    • Parker, L., S. Atherton-Fessler, and H. Piwnica-Worms. 1992. p107wee1 is a dual-specificity kinase that phosphorylates p34cdc2 on tyrosine 15. Proc. Natl. Acad. Sci. 89: 2917-2921.
    • (1992) Proc. Natl. Acad. Sci. , vol.89 , pp. 2917-2921
    • Parker, L.1    Atherton-Fessler, S.2    Piwnica-Worms, H.3
  • 64
    • 0028176483 scopus 로고
    • Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals
    • Polyak, K., M.H. Lee, H. Erdjument-Bromage, A. Koff, J.M. Roberts, P. Tempst, and J. Massague. 1994a. Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals. Cell 78: 59-66.
    • (1994) Cell , vol.78 , pp. 59-66
    • Polyak, K.1    Lee, M.H.2    Erdjument-Bromage, H.3    Koff, A.4    Roberts, J.M.5    Tempst, P.6    Massague, J.7
  • 65
    • 0028179669 scopus 로고
    • p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest
    • Polyak, K., J.Y. Kato, M.J. Solomon, C.J. Sherr, J. Massague, J.M. Roberts, and A. Koff. 1994b. p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest. Genes & Dev. 8: 9-22.
    • (1994) Genes & Dev. , vol.8 , pp. 9-22
    • Polyak, K.1    Kato, J.Y.2    Solomon, M.J.3    Sherr, C.J.4    Massague, J.5    Roberts, J.M.6    Koff, A.7
  • 68
    • 0018294520 scopus 로고
    • Synthesis of labile, serum-dependent protein in early G1 controls animal cell growth
    • Rossow, P.W., V.G.H. Riddle, and A.B. Pardee. 1979. Synthesis of labile, serum-dependent protein in early G1 controls animal cell growth. Proc. Natl. Acad. Sci. 76: 4446-4450.
    • (1979) Proc. Natl. Acad. Sci. , vol.76 , pp. 4446-4450
    • Rossow, P.W.1    Riddle, V.G.H.2    Pardee, A.B.3
  • 69
    • 0022462146 scopus 로고
    • cdc25+ functions as an inducer in the mitotic control of fission yeast
    • Russell, P. and P. Nurse. 1986. cdc25+ functions as an inducer in the mitotic control of fission yeast. Cell 45: 145-153.
    • (1986) Cell , vol.45 , pp. 145-153
    • Russell, P.1    Nurse, P.2
  • 70
    • 0023662312 scopus 로고
    • Negative regulation of mitosis by wee1+, a gene encoding a protein kinase homolog
    • _. 1987. Negative regulation of mitosis by wee1+, a gene encoding a protein kinase homolog. Cell 49: 559-567.
    • (1987) Cell , vol.49 , pp. 559-567
  • 71
    • 0025324692 scopus 로고
    • Human homolog of fission yeast cdc25 mitotic inducer is predominantly expressed in G2
    • Sadhu, K., S.I. Reed, H. Richardson, and P. Russell. 1990. Human homolog of fission yeast cdc25 mitotic inducer is predominantly expressed in G2. Proc. Natl. Acad. Sci. 87: 5139-5143.
    • (1990) Proc. Natl. Acad. Sci. , vol.87 , pp. 5139-5143
    • Sadhu, K.1    Reed, S.I.2    Richardson, H.3    Russell, P.4
  • 73
  • 74
    • 0027769876 scopus 로고
    • A new regulatory motif in cell cycle control causing specific inhibition of cyclin D/CDK4
    • Serrano, M., G. Hannon, and D. Beach. 1993. A new regulatory motif in cell cycle control causing specific inhibition of cyclin D/CDK4. Nature 366: 704-707.
    • (1993) Nature , vol.366 , pp. 704-707
    • Serrano, M.1    Hannon, G.2    Beach, D.3
  • 75
    • 0028171292 scopus 로고
    • G1-phase progression: Cycling on cue
    • Sherr, C.J. 1994. G1-phase progression: cycling on cue. Cell 79: 817-825.
    • (1994) Cell , vol.79 , pp. 817-825
    • Sherr, C.J.1
  • 76
    • 0027007963 scopus 로고
    • The role of phosphorylation in p34cdk2 activation: Identification of an activating kinase
    • Solomon, M., T. Lee, and M. Kirschner. 1992. The role of phosphorylation in p34cdk2 activation: Identification of an activating kinase. Mol. Biol. Cell 3: 13-27.
    • (1992) Mol. Biol. Cell , vol.3 , pp. 13-27
    • Solomon, M.1    Lee, T.2    Kirschner, M.3
  • 77
    • 0026336517 scopus 로고
    • Dominant inhibitory Ras mutants demonstrate the requirement for Ras activity in the action of tyrosine kinase oncogenes
    • Stacey, D.W., M. Roudebush, R. Day, S.D. Mosser, J.B. Gibbs, and L.A. Feig. 1991. Dominant inhibitory Ras mutants demonstrate the requirement for Ras activity in the action of tyrosine kinase oncogenes. Oncogene 6: 2297-2304.
    • (1991) Oncogene , vol.6 , pp. 2297-2304
    • Stacey, D.W.1    Roudebush, M.2    Day, R.3    Mosser, S.D.4    Gibbs, J.B.5    Feig, L.A.6
  • 78
    • 0024545162 scopus 로고
    • Definition of the human raf amino-terminal regulatory region by deletion mutagenesis
    • Stanton, V.P. Jr., D.W. Nichols, A.P. Laudano, and G.M. Cooper. 1989. Definition of the human raf amino-terminal regulatory region by deletion mutagenesis. Mol. Cell Biol. 9: 639-647.
    • (1989) Mol. Cell Biol. , vol.9 , pp. 639-647
    • Stanton Jr., V.P.1    Nichols, D.W.2    Laudano, A.P.3    Cooper, G.M.4
  • 79
    • 0028241533 scopus 로고
    • Activation of Raf as a result of recruitment to the plasma membrane
    • Stokoe, D., S.G. Macdonald, K. Cadwallader, M. Symons, and J.F. Hancock. 1994. Activation of Raf as a result of recruitment to the plasma membrane. Science 264: 1463-1467.
    • (1994) Science , vol.264 , pp. 1463-1467
    • Stokoe, D.1    Macdonald, S.G.2    Cadwallader, K.3    Symons, M.4    Hancock, J.F.5
  • 81
    • 0022915860 scopus 로고
    • The clam embryo protein cyclin A induces entry into M phase and the resumption of meiosis in Xenopus oocytes
    • Swenson, K.I., K.M. Farrell, and J.V. Ruderman. 1986. The clam embryo protein cyclin A induces entry into M phase and the resumption of meiosis in Xenopus oocytes. Cell 47: 861-870.
    • (1986) Cell , vol.47 , pp. 861-870
    • Swenson, K.I.1    Farrell, K.M.2    Ruderman, J.V.3
  • 82
    • 0026534571 scopus 로고
    • Ras is essential for nerve growth factor-and phorbol ester-induced tyrosine phosphorylation of MAP kinases
    • Thomas, S.M., M. DeMarco, G. D'Arcangelo, S. Halegoua, and J.S. Brugge. 1992. Ras is essential for nerve growth factor-and phorbol ester-induced tyrosine phosphorylation of MAP kinases. Cell 68: 1031-1040.
    • (1992) Cell , vol.68 , pp. 1031-1040
    • Thomas, S.M.1    Demarco, M.2    D'Arcangelo, G.3    Halegoua, S.4    Brugge, J.S.5
  • 83
    • 0028363519 scopus 로고
    • p27, a novel inhibitor of G1 cyclin-cdk protein kinase activity, is related to p21
    • Toyoshima, H. and T. Hunter. 1994. p27, a novel inhibitor of G1 cyclin-cdk protein kinase activity, is related to p21. Cell 78: 67-74.
    • (1994) Cell , vol.78 , pp. 67-74
    • Toyoshima, H.1    Hunter, T.2
  • 84
    • 0027527919 scopus 로고
    • Specific association of activated MAP kinase kinase kinase (Raf) with the plasma membranes of ras-transformed retinal cells
    • Traverse, S., P. Cohen, H. Paterson, C. Marshall, U. Rapp, and R.J. Grand. 1993. Specific association of activated MAP kinase kinase kinase (Raf) with the plasma membranes of ras-transformed retinal cells. Oncogene 8: 3175-3181.
    • (1993) Oncogene , vol.8 , pp. 3175-3181
    • Traverse, S.1    Cohen, P.2    Paterson, H.3    Marshall, C.4    Rapp, U.5    Grand, R.J.6
  • 86
    • 0028227245 scopus 로고
    • The native structure of the activated Raf protein kinase is a membrane-bound multi-subunit complex
    • Wartmann, M. and R.J. Davis. 1994. The native structure of the activated Raf protein kinase is a membrane-bound multi-subunit complex. J. Biol. Chem. 269: 6695-6701.
    • (1994) J. Biol. Chem. , vol.269 , pp. 6695-6701
    • Wartmann, M.1    Davis, R.J.2
  • 87
    • 0026611532 scopus 로고
    • src are required, but neither alone is sufficient, to activate the Raf-1 kinase
    • src are required, but neither alone is sufficient, to activate the Raf-1 kinase. Proc. Natl. Acad. Sci. 89: 2922-2926.
    • (1992) Proc. Natl. Acad. Sci. , vol.89 , pp. 2922-2926
    • Williams, N.G.1    Roberts, T.M.2    Li, P.3
  • 89
    • 0026699554 scopus 로고
    • Growth-regulated expression of D-type cyclin genes in human diploid fibroblasts
    • Won, K.A., Y. Xiong, D. Beach, and M.Z. Gilman. 1992. Growth-regulated expression of D-type cyclin genes in human diploid fibroblasts. Proc. Natl. Acad. Sci. 89: 9910-9914.
    • (1992) Proc. Natl. Acad. Sci. , vol.89 , pp. 9910-9914
    • Won, K.A.1    Xiong, Y.2    Beach, D.3    Gilman, M.Z.4
  • 90
    • 0026523559 scopus 로고
    • Ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK
    • Wood, K.W., C. Sarnecki, T.M. Roberts, and J. Blenis. 1992. Ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK. Cell 68: 1041-1050.
    • (1992) Cell , vol.68 , pp. 1041-1050
    • Wood, K.W.1    Sarnecki, C.2    Roberts, T.M.3    Blenis, J.4
  • 93
    • 0028670788 scopus 로고
    • Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator, SEK1
    • Yan, M., T. Dai, J.C. Deak, J.M. Kyriakis, L.I. Zon, J.R. Woodgett, and D.J. Templeton. 1994. Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator, SEK1. Nature 370: 798-801.
    • (1994) Nature , vol.370 , pp. 798-801
    • Yan, M.1    Dai, T.2    Deak, J.C.3    Kyriakis, J.M.4    Zon, L.I.5    Woodgett, J.R.6    Templeton, D.J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.