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Volumn 55, Issue 13, 1995, Pages 2794-2799

Tyrphostin AG17, [(3,5-Di-tert-butyl-4-hydroxybenzylidene)-malononitrile], Inhibits Cell Growth by Disrupting Mitochondria

Author keywords

[No Author keywords available]

Indexed keywords

3,5 DI TERT BUTYL 4 HYDROXYBENZYLIDENEMALONONITRILE; ADENOSINE TRIPHOSPHATE; ANTIMYCIN A1; CARBONYL CYANIDE CHLOROPHENYLHYDRAZONE; OLIGOMYCIN; PROTEIN TYROSINE KINASE INHIBITOR; RHODAMINE 123; TYRPHOSTIN;

EID: 0029034225     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (41)

References (23)
  • 1
    • 0024434810 scopus 로고
    • Tyrphostins 1: synthesis and biological activity of protein tyrosine kinase inhibitors
    • Gazit, A., Yaish, P., Gilon, C., and Levitzki, A. Tyrphostins 1: synthesis and biological activity of protein tyrosine kinase inhibitors. J. Med. Chem., 32: 2344–2362, 1989.
    • (1989) J. Med. Chem. , vol.32 , pp. 2344-2362
    • Gazit, A.1    Yaish, P.2    Gilon, C.3    Levitzki, A.4
  • 2
    • 0025160266 scopus 로고
    • Tyrphostins—potential antiproliferative agents and novel molecular tools
    • Levitzki, A. Tyrphostins—potential antiproliferative agents and novel molecular tools. Biochem. Pharmacol., 40: 913–918, 1990.
    • (1990) Biochem. Pharmacol. , vol.40 , pp. 913-918
    • Levitzki, A.1
  • 3
    • 0026458235 scopus 로고
    • Tyrphostins: tyrosine kinase blockers as novel antiproliferative agents and dissectors of signal transduction
    • Levitzki, A. Tyrphostins: tyrosine kinase blockers as novel antiproliferative agents and dissectors of signal transduction. FASEB J., 6: 3275–3282, 1992.
    • (1992) FASEB J. , vol.6 , pp. 3275-3282
    • Levitzki, A.1
  • 5
    • 0027491224 scopus 로고
    • Inhibition of pancreatic cancer cell growth in vitro by the tyrphostin group of tyrosine kinase inhibitors
    • Gillespie, J., Dye, J. F., Schachter, M., and Guillou, P. J. Inhibition of pancreatic cancer cell growth in vitro by the tyrphostin group of tyrosine kinase inhibitors. Br. J. Cancer, 68: 1122–1126, 1993.
    • (1993) Br. J. Cancer , vol.68 , pp. 1122-1126
    • Gillespie, J.1    Dye, J.F.2    Schachter, M.3    Guillou, P.J.4
  • 6
    • 0026648901 scopus 로고
    • Selective interactions of transforming and normal abl proteins with, ATP tyrosine-copolymer substrates and tyrphostins
    • Anafi, M., Gazit, A., Gilon, C., Ben-Neriah, Y., and Levitzki, A. Selective interactions of transforming and normal abl proteins with, ATP tyrosine-copolymer substrates and tyrphostins. J. Biol. Chem., 267: 4518–4523, 1992.
    • (1992) J. Biol. Chem. , vol.267 , pp. 4518-4523
    • Anafi, M.1    Gazit, A.2    Gilon, C.3    Ben-Neriah, Y.4    Levitzki, A.5
  • 8
    • 0009920393 scopus 로고
    • Identification of the antitumor activity and preclinical evaluation of the benzyliden-emalononitrile derivative NSC 242557
    • Supko, J. G., Malspeis, L., Sausville, E. A., Burger, A., Alley, M., and Grever, M. R. Identification of the antitumor activity and preclinical evaluation of the benzyliden-emalononitrile derivative NSC 242557. Proc. Am. Assoc. Cancer Res., 35:424,1994.
    • (1994) Proc. Am. Assoc. Cancer Res. , vol.35 , pp. 424
    • Supko, J.G.1    Malspeis, L.2    Sausville, E.A.3    Burger, A.4    Alley, M.5    Grever, M.R.6
  • 10
    • 0025793990 scopus 로고
    • Tyrphostins as molecular tools and potential antiproliferative drugs
    • Levitzki, A., and Gilon, G. Tyrphostins as molecular tools and potential antiproliferative drugs. Trends Pharmacol. Sci., 12: 171–173, 1991.
    • (1991) Trends Pharmacol. Sci. , vol.12 , pp. 171-173
    • Levitzki, A.1    Gilon, G.2
  • 11
    • 0026671829 scopus 로고
    • Agonistic effects of tyrphostins on human peripheral mononuclear cells
    • Lander, H. N., Levine, D. M., and Novogrodsky, A. Agonistic effects of tyrphostins on human peripheral mononuclear cells. Cell. Immunol., 144: 155–168, 1992.
    • (1992) Cell. Immunol. , vol.144 , pp. 155-168
    • Lander, H.N.1    Levine, D.M.2    Novogrodsky, A.3
  • 12
    • 0023805842 scopus 로고
    • Reactivity of mitochondrial sulfhydryl groups toward dithionitrobenzoic acid and bromobimanes under oligomy-cin-inhibited and uncoupling conditions
    • Freisleben, H. J., Fuchs, J., Mainka, L., and Zimmer, G. Reactivity of mitochondrial sulfhydryl groups toward dithionitrobenzoic acid and bromobimanes under oligomy-cin-inhibited and uncoupling conditions. Arch. Biochem. Biophys., 266: 89–97, 1988.
    • (1988) Arch. Biochem. Biophys. , vol.266 , pp. 89-97
    • Freisleben, H.J.1    Fuchs, J.2    Mainka, L.3    Zimmer, G.4
  • 13
    • 0021771524 scopus 로고
    • Molecular basis of the protonophoric and uncoupling activities of the potent uncoupler SF-6847 ((3,5-di-tert-butyl-4-hydroxybenzylidene)malononitrile) and derivatives. Regulation of their electronic structures by restricted intramolecular rotation
    • Terada, H., Kumazawa, N., Ju-Ichi, M., and Yoshikawa, K. Molecular basis of the protonophoric and uncoupling activities of the potent uncoupler SF-6847 ((3,5-di-tert-butyl-4-hydroxybenzylidene)malononitrile) and derivatives. Regulation of their electronic structures by restricted intramolecular rotation. Biochim. Biophys. Acta., 767: 192–199, 1984.
    • (1984) Biochim. Biophys. Acta. , vol.767 , pp. 192-199
    • Terada, H.1    Kumazawa, N.2    Ju-Ichi, M.3    Yoshikawa, K.4
  • 15
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays
    • Mosmann, T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods, 65: 55–63, 1983.
    • (1983) J. Immunol. Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 17
    • 77956986494 scopus 로고
    • Purification and properties of firefly luciferase
    • DeLuca, M., and McElroy, W. D. Purification and properties of firefly luciferase. Methods Enzymol., 57: 3–15, 1978.
    • (1978) Methods Enzymol. , vol.57 , pp. 3-15
    • DeLuca, M.1    McElroy, W.D.2
  • 18
    • 0019480519 scopus 로고
    • Monitoring of relative mitochondrial membrane potential in living cells by fluorescence microscopy
    • Johnson, L. V., Walsh, M. L., Bockus, B. J., and Chen, L. B. Monitoring of relative mitochondrial membrane potential in living cells by fluorescence microscopy. J. Cell Biol., 88: 526–535, 1981.
    • (1981) J. Cell Biol. , vol.88 , pp. 526-535
    • Johnson, L.V.1    Walsh, M.L.2    Bockus, B.J.3    Chen, L.B.4
  • 19
    • 0027049775 scopus 로고
    • Disruption of mitochondrial function by suramin measured by rhodamine 123 retention and oxygen consumption in intact DU 145 prostate carcinoma cells
    • Rago, R. P., Brazy, P. C., and Wilding, G. Disruption of mitochondrial function by suramin measured by rhodamine 123 retention and oxygen consumption in intact DU 145 prostate carcinoma cells. Cancer Res., 52: 6953–6955, 1992.
    • (1992) Cancer Res. , vol.52 , pp. 6953-6955
    • Rago, R.P.1    Brazy, P.C.2    Wilding, G.3
  • 20
    • 0026340639 scopus 로고
    • Disruption of cellular energy balance by suramin in intact human prostatic carcinoma cells, a likely antiproliferative mechanism
    • Rago, R. P., Mitchen, J., Cheng, A. L., Oberly, T., and Wilding, G. Disruption of cellular energy balance by suramin in intact human prostatic carcinoma cells, a likely antiproliferative mechanism. Cancer Res., 57: 6629–6635, 1991.
    • (1991) Cancer Res. , vol.57 , pp. 6629-6635
    • Rago, R.P.1    Mitchen, J.2    Cheng, A.L.3    Oberly, T.4    Wilding, G.5
  • 21
    • 0024375793 scopus 로고
    • Comparative features of a coronavirus isolated from a cheetah with feline infectious peritonitis
    • Evermann, J. F., Heeney, J. L., McKeirnan, A. J., and O'Brian, S. J. Comparative features of a coronavirus isolated from a cheetah with feline infectious peritonitis. Virus Res., 75: 15–28, 1989.
    • (1989) Virus Res. , vol.75 , pp. 15-28
    • Evermann, J.F.1    Heeney, J.L.2    McKeirnan, A.J.3    O'Brian, S.J.4
  • 22
    • 0027349240 scopus 로고
    • Tyrphostins inhibit Sertoli cell-secreted growth factor stimulation of A431 cell growth
    • Lamb, D. J., and Sankararaman, S. Tyrphostins inhibit Sertoli cell-secreted growth factor stimulation of A431 cell growth. Recent Prog. Horm. Res., 48: 511–516,1993.
    • (1993) Recent Prog. Horm. Res. , vol.48 , pp. 511-516
    • Lamb, D.J.1    Sankararaman, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.