Melatonin stimulates brain glutathione peroxidase activity

Neurochemistry International

Volumn 26, Issue 5, 1995, Pages 497-502

  Barlow Walden, L R ^a   Reiter, R J ^a   Abe, M ^a   Pablos, M ^a   Menendez Pelaez, A ^a   Chen, L D ^a   Poeggeler, B ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; BRAIN ENZYME; BRAIN PROTEIN; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; HYDROXYL RADICAL; MELATONIN; PEROXIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN LEVEL; BRAIN PROTECTION; CELL PROTECTION; CIRCADIAN RHYTHM; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; HORMONAL REGULATION; NERVE CELL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ANIMALS; BRAIN; FEMALE; FREE RADICAL SCAVENGERS; GLUTATHIONE PEROXIDASE; HYDROXYL RADICAL; MELATONIN; RATS; RATS, SPRAGUE-DAWLEY; STIMULATION, CHEMICAL;

ANIMALIA;

EID: 0029032902     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/0197-0186(94)00154-M     Document Type: Article

References (30)

1. Neurochemical aspects of aging in primates
2. Prevention of microsomal production of hydroxyl radicals, but not lipid peroxidation, by the glutathione-glutathione peroxidase system
3. Concurrent determination of enzymatic activities and substrate concentrations in the melatonin synthetic pathway within the same rat
4. 2+-stimulated ATPase activity induced by alloxan
5. 2+]-dependent ATPase in cardiac carcolemma
6. Protection by dihydroergocryptine of glutamate-induced neutroxicity
7. Direct radioimmunoassay for melatonin in plasma
8. Cu//Zn superoxide dismutase mRNA and enzyme activity and susceptibility to lipid peroxidation increases with aging in murine brains
9. The significance of the metabolism of the neurohormone melatonin : antioxidative protection and formation of bioactive substances
10. Effects of a novel melatonin analog on circadian rhythms of body temperature and activity in young, middle-aged, and old rats
11. Euthanasia by decapitation: evidence that this technique produces prompt, painless unconsciousness in laboratory rodents
12. An automated analysis of glutathione peroxidase, glutathione-S-transferase, and reductase activity in animal tissue
13. Importance of Se-glutathione peroxidase catalase and Cu/Zn-SOD for cell survival against oxidative stress
14. Enhancement of renaland hepatic glutathione metabolism by dimethylurea
15. Transgenic glutathione peroxidase mice models for neuroprotection studies
16. Free radical scavenging by brain hemogenate : implication to free radical damage and antioxidative defense in brain
17. NGF restores decrease in catalase activity and increases superoxide dismutase and glutathione peroxidase activity in the brain of aged rats
18. Pineal control of aging effect of melatonin and pineal grafting on aging mice
19. Susceptibility of glutathione peroxidase to proteolysis after oxidative alterations by peroxides and hydroxyl radicals
20. Melatonin, hydroxyl radical-mediated oxidative damage, and aging: a hypothesis
21. Melatonin—a highly potent endogenous radical scavenger and electron donor new aspects of the oxidation chemistry of this indole accessed in vitro
22. Comparative study on the enzymatic defense systems against oxygenderived free radicals: the key role of glutathione peroxidase
23. Antoxidant activity of melatonin : a novel action not requiring a receptor
24. Melatonin as a radical scavenger: implications for aging and diseases
25. Melatonin as a free radical scavenger: theoretical implications for neurodegenerative disorders in the aged
26. Biochemical correlates of longevity in two closely related rodent species
27. Susceptibility of glutathione peroxidase and glutathione reductase to oxidative damage and protective effect of spin trapping agents
28. Melatonin: a potent, endogenous hydroxyl radical scavenger
29. Both physiological and pharmacological levels of melatonin reduce DNA adduct formation induced by the chemical carcinogen safrole
30. The pineal hormone melatonin inhibits DNA-adduct formation induced by the chemical carcinogen safrole in vivo