A gene therapy strategy using a transcription factor decoy of the E2F binding site inhibits smooth muscle proliferation in vivo

Proceedings of the National Academy of Sciences of the United States of America

Volumn 92, Issue 13, 1995, Pages 5855-5859

  Morishita, Ryuichi ^a   Gibbons, Gary H ^a   Horiuchi, Masatsugu ^a   Ellison, Kristin E ^a   Nakajima, Masatoshi ^a   Zhang, Lunan ^a   Kaneda, Yasufumi ^b   Ogihara, Toshio ^c   Dzau, Victor J ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^c OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

antigene; cell cycle regulatory genes; hemagglutinating virus of Japan; restenosis

Indexed keywords

CYCLINE; DOUBLE STRANDED DNA; OLIGODEOXYNUCLEOTIDE; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL MODEL; ARTERY INTIMA PROLIFERATION; ARTICLE; CELL PROLIFERATION; COMMON CAROTID ARTERY; CONTROLLED STUDY; DNA SYNTHESIS; GENE THERAPY; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REGULATOR GENE; TRANSACTIVATION; VASCULAR SMOOTH MUSCLE;

ANIMAL; AORTA; BASE SEQUENCE; BINDING SITES; CELL DIVISION; CELL NUCLEUS; CELLS, CULTURED; COMPARATIVE STUDY; DNA PRIMERS; DRUG CARRIERS; GENE THERAPY; GENES, MYC; LIPOSOMES; MOLECULAR SEQUENCE DATA; MUSCLE, SMOOTH, VASCULAR; OLIGODEOXYRIBONUCLEOTIDES; POLYMERASE CHAIN REACTION; PROLIFERATING CELL NUCLEAR ANTIGEN; PROMOTER REGIONS (GENETICS); PROTEIN P34CDC2; RATS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; TRANSFECTION;

ANIMALIA;

EID: 0029031549     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.92.13.5855     Document Type: Article

References (28)