메뉴 건너뛰기




Volumn 45, Issue 1, 1995, Pages 1-45

Toxicity of quinolone antimicrobial agents

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; AT 954; BAY O 9863; CINOXACIN; CIPROFLOXACIN; ENOXACIN; FLEROXACIN; LEVOFLOXACIN; LOMEFLOXACIN; NALIDIXIC ACID; NONSTEROID ANTIINFLAMMATORY AGENT; NORFLOXACIN; OFLOXACIN; PEFLOXACIN; PIPEMIDIC ACID; PIROMIDIC ACID; QUINOLONE DERIVATIVE; S 7920; SPARFLOXACIN; TOSUFLOXACIN; TOSUFLOXACIN TOSILATE; UNCLASSIFIED DRUG;

EID: 0029028389     PISSN: 00984108     EISSN: None     Source Type: Journal    
DOI: 10.1080/15287399509531978     Document Type: Article
Times cited : (97)

References (229)
  • 1
    • 0027055905 scopus 로고
    • Effects of interactions between several new quinolone antimi-crobials and fenbufen on the responses of receptors for inhibitory amino acids in acutely isolated neurons from the rat hippocampus (CA1) 1
    • Abe, H., Inokuchi, K., and Fujita, K. 1992. Effects of interactions between several new quinolone antimi-crobials and fenbufen on the responses of receptors for inhibitory amino acids in acutely isolated neurons from the rat hippocampus (CA1) 1. Ohyo Yakuri 44:679-683.
    • (1992) Ohyo Yakuri , vol.44 , pp. 679-683
    • Abe, H.1    Inokuchi, K.2    Fujita, K.3
  • 2
    • 0027293522 scopus 로고
    • Interaction of new quinolone antimicrobials and fenbufen in producing responses of GABA receptors in acutely isolated neurons from the rat hippocampus (CA1) (2)
    • Abe, H., Inokuchi, K., and Fujita, K. 1993. Interaction of new quinolone antimicrobials and fenbufen in producing responses of GABA receptors in acutely isolated neurons from the rat hippocampus (CA1) (2). Ohyo Yakuri 46:29-32.
    • (1993) Ohyo Yakuri , vol.46 , pp. 29-32
    • Abe, H.1    Inokuchi, K.2    Fujita, K.3
  • 3
    • 0024692565 scopus 로고
    • Use of quinolones in pediatric patients
    • Adam, D. 1989. Use of quinolones in pediatric patients. Rev. Infect. Dis. 11 (suppl. 5):S1113-S1116.
    • (1989) Rev. Infect. Dis , vol.11 , pp. S1113-S1116
    • Adam, D.1
  • 4
    • 0024444018 scopus 로고
    • Structure-epileptogenicity relationship of quinolones with special reference to their interaction with y-aminobutyric acid receptor sites
    • Akahane, K., Sekiguchi, M., Une, T., and Osada, Y. 1989. Structure-epileptogenicity relationship of quinolones with special reference to their interaction with y-aminobutyric acid receptor sites. Antimicrob. Agents Chemother. 33:1704-1708.
    • (1989) Antimicrob. Agents Chemother , vol.33 , pp. 1704-1708
    • Akahane, K.1    Sekiguchi, M.2    Une, T.3    Osada, Y.4
  • 7
    • 0023514218 scopus 로고
    • Photodamage to the eye
    • Andley, U. P. 1987. Photodamage to the eye. Photochem. Photobiol. 46:1057-1066.
    • (1987) Photochem. Photobiol , vol.46 , pp. 1057-1066
    • Andley, U.P.1
  • 10
    • 0024604630 scopus 로고
    • A novel mechanism for the generation of superoxide anions in hematoporphyrin derivative-mediated cutaneous photosensitization: Activa-tion of the xanthine oxidase pathway
    • Athar, M., Elmets, C. A., Bickers, D. R., and Mukhtar, H. 1989. A novel mechanism for the generation of superoxide anions in hematoporphyrin derivative-mediated cutaneous photosensitization: Activa-tion of the xanthine oxidase pathway. J. Clin. Invest. 83:1137-1143.
    • (1989) J. Clin. Invest , vol.83 , pp. 1137-1143
    • Athar, M.1    Elmets, C.A.2    Bickers, D.R.3    Mukhtar, H.4
  • 11
    • 0003030146 scopus 로고
    • Photosensitivity caused by nalidixic acid
    • Baes, H. 1968. Photosensitivity caused by nalidixic acid. Dermatologica 136:61-64.
    • (1968) Dermatologica , vol.136 , pp. 61-64
    • Baes, H.1
  • 13
    • 0022975545 scopus 로고
    • Ciprofloxacin: An overview of adverse experiences
    • Ball, P. 1986. Ciprofloxacin: An overview of adverse experiences. I. Antimicrob. Chemother. 18(suppl. D): 187-193.
    • (1986) I. Antimicrob. Chemother , vol.18 , pp. 187-193
    • Ball, P.1
  • 15
    • 0027181024 scopus 로고
    • Effects of ciprofloxacin on chromosomes, and hepatic and renal functions in rats
    • Basaran, A., Erol, K., Basaran, N., Gunes, H., Acikalin, E., and Timuralp, G. 1993. Effects of ciprofloxacin on chromosomes, and hepatic and renal functions in rats. Chemotherapy 39:182-188.
    • (1993) Chemotherapy , vol.39 , pp. 182-188
    • Basaran, A.1    Erol, K.2    Basaran, N.3    Gunes, H.4    Acikalin, E.5    Timuralp, G.6
  • 16
    • 0025885325 scopus 로고
    • Comparison of the effect of temafloxacin, ciprofloxacin, or placebo on cerebral blood flow, glucose, and oxygen metabolism in healthy subjects by means of positron emission tomography
    • Bednarczyk, E. M., Green, J. A., Nelson, A. D., Leisure, G. A., Little, D., Adler, L. P., Berridge, M. S., Panacek, E. A., and Miraldi, F. D. 1991. Comparison of the effect of temafloxacin, ciprofloxacin, or placebo on cerebral blood flow, glucose, and oxygen metabolism in healthy subjects by means of positron emission tomography. Clin. Pharmacol. Ther. 50:165-171.
    • (1991) Clin. Pharmacol. Ther , vol.50 , pp. 165-171
    • Bednarczyk, E.M.1    Green, J.A.2    Nelson, A.D.3    Leisure, G.A.4    Little, D.5    Adler, L.P.6    Berridge, M.S.7    Panacek, E.A.8    Miraldi, F.D.9
  • 17
    • 0025023882 scopus 로고
    • Passive role of articular chondrocytes in quinolone-induced arthropathy in guinea pigs
    • Bendele, A. M., Hulman, J. F., Harvey, A. K., Hrubey, P. S., and Chandrasekhar, S. 1990. Passive role of articular chondrocytes in quinolone-induced arthropathy in guinea pigs. Toxicol. Pathol. 18:304-312.
    • (1990) Toxicol. Pathol , vol.18 , pp. 304-312
    • Bendele, A.M.1    Hulman, J.F.2    Harvey, A.K.3    Hrubey, P.S.4    Chandrasekhar, S.5
  • 18
    • 84966175904 scopus 로고
    • A new quantitative approach to the study of the stages of chemi-cal carcinogenesis in the mouse’s skin
    • Berenblum, I., and Shubik, P. K. 1947. A new quantitative approach to the study of the stages of chemi-cal carcinogenesis in the mouse’s skin. Br. I. Cancer 1:386-391.
    • (1947) Br. I. Cancer , vol.1 , pp. 386-391
    • Berenblum, I.1    Shubik, P.K.2
  • 19
    • 0014515572 scopus 로고
    • Phototoxic bullous eruptions due to nalidixic acid
    • Birkett, D. A., Garretts, M., and Stevenson, C. J. 1969. Phototoxic bullous eruptions due to nalidixic acid. Br. J. Dermatol. 81:342-344.
    • (1969) Br. J. Dermatol , vol.81 , pp. 342-344
    • Birkett, D.A.1    Garretts, M.2    Stevenson, C.J.3
  • 20
    • 0022844046 scopus 로고
    • Safety of ofloxacin-Adverse drug reactions reported during phase-ll studies in Europe and Japan
    • Blomer, R., Bruch, K., Krauss, H., and Wacheck, W. 1986. Safety of ofloxacin-Adverse drug reactions reported during phase-ll studies in Europe and Japan. Infection 14(suppl. 4):S332-S334.
    • (1986) Infection , vol.14 , pp. S332-S334
    • Blomer, R.1    Bruch, K.2    Krauss, H.3    Wacheck, W.4
  • 21
    • 0018266552 scopus 로고
    • Toxicologie experimentale.-Tissus car-tilagineux et acide nalidixique. C. R
    • Bouissou, H., Caujolle, D., Caujolle, F., and Milhaud, G. 1978. Toxicologie experimentale.-Tissus car-tilagineux et acide nalidixique. C. R. Acad. Sci. Paris 286:D1743-1746.
    • (1978) Acad. Sci. Paris , vol.286 , pp. D1743-D1746
    • Bouissou, H.1    Caujolle, D.2    Caujolle, F.3    Milhaud, G.4
  • 22
    • 0024441515 scopus 로고
    • Adverse reactions in a dose-ranging study with a new long-acting fluoroquinolone, fleroxacin
    • Bowie, W., Willetts, V., and Jewesson, P. T. 1989. Adverse reactions in a dose-ranging study with a new long-acting fluoroquinolone, fleroxacin. Antimicrob. Agents Chemother. 33:1778-1782.
    • (1989) Antimicrob. Agents Chemother , vol.33 , pp. 1778-1782
    • Bowie, W.1    Willetts, V.2    Jewesson, P.T.3
  • 23
    • 0016740184 scopus 로고
    • Bullous photoreaction to nalidixic acid
    • Brauner, G. J. 1975. Bullous photoreaction to nalidixic acid. Am. J. Med. 58:576-580.
    • (1975) Am. J. Med , vol.58 , pp. 576-580
    • Brauner, G.J.1
  • 24
    • 0024586601 scopus 로고
    • 4-Quinolone antibiotics: Positive genotoxic screening tests despite an apparent lack of mutation induction
    • Bredberg, A., Brant, M., Riesbeck, K., Azou, Y., and Forsgren, A. 1989. 4-Quinolone antibiotics: Positive genotoxic screening tests despite an apparent lack of mutation induction. Mutât Res. 211:171-180.
    • (1989) Mutât Res , vol.211 , pp. 171-180
    • Bredberg, A.1    Brant, M.2    Riesbeck, K.3    Azou, Y.4    Forsgren, A.5
  • 25
    • 0021509032 scopus 로고
    • Transmission of human epidermis and stratum corneum as a function of thickness in the ultraviolet and visible wavelengths
    • Bruis, W. A., Slaper, H., Van Der Leu, J. C., and Berreus, L. 1984. Transmission of human epidermis and stratum corneum as a function of thickness in the ultraviolet and visible wavelengths. Pbotochem. Pbotobiol. 40:485-494.
    • (1984) Pbotochem. Pbotobiol , vol.40 , pp. 485-494
    • Bruis, W.A.1    Slaper, H.2    Van Der Leu, J.C.3    Berreus, L.4
  • 26
    • 0025323636 scopus 로고
    • Histologic and histochemical changes in articular cartilages of immature beagle dogs dosed with difloxacin, a fluoroquinolone
    • Burkhardt, J. E., Hill, M. A., Carlton, W. W., and Kesterson, J. W. 1990. Histologic and histochemical changes in articular cartilages of immature beagle dogs dosed with difloxacin, a fluoroquinolone. Vet. Pathol. 27:162-170.
    • (1990) Vet. Pathol , vol.27 , pp. 162-170
    • Burkhardt, J.E.1    Hill, M.A.2    Carlton, W.W.3    Kesterson, J.W.4
  • 27
    • 0026718620 scopus 로고
    • Ultrastructural changes in articular cartilages of immature beagle dogs dosed with difloxacin, a fluoroquinolone
    • Burkhardt, J. E., Hill, M. A., Turek, J. J., and Carlton, W. W. 1992a. Ultrastructural changes in articular cartilages of immature beagle dogs dosed with difloxacin, a fluoroquinolone. Vet. Pathol. 29:230-238.
    • (1992) Vet. Pathol , vol.29 , pp. 230-238
    • Burkhardt, J.E.1    Hill, M.A.2    Turek, J.J.3    Carlton, W.W.4
  • 28
    • 0026727108 scopus 로고
    • Morphologic and biochemical changes in artic-ular cartilages of immature beagle dogs dosed with difloxacin
    • Burkhardt, J. E., Hill, M. A., and Carlton, W. W. 1992b. Morphologic and biochemical changes in artic-ular cartilages of immature beagle dogs dosed with difloxacin. Toxicol. Pathol. 20:246-252.
    • (1992) Toxicol. Pathol , vol.20 , pp. 246-252
    • Burkhardt, J.E.1    Hill, M.A.2    Carlton, W.W.3
  • 29
    • 77957180458 scopus 로고
    • Effects of difloxacin on the metabolism of glycosaminoglycans and collagen in organ cultures of articular cartilage
    • Burkhardt, J. E., Hill, M. A., Lamar, C. H., Smith, G. N., Jr., and Carlton, W. W. 1993. Effects of difloxacin on the metabolism of glycosaminoglycans and collagen in organ cultures of articular cartilage. Fundam. Appl. Toxicol. 20:257-263.
    • (1993) Fundam. Appl. Toxicol , vol.20 , pp. 257-263
    • Burkhardt, J.E.1    Hill, M.A.2    Lamar, C.H.3    Smith, G.N.4    Carlton, W.W.5
  • 30
    • 0016029761 scopus 로고
    • Persistent phototoxicity due to nalidixic acid
    • Burry, J. N. 1974. Persistent phototoxicity due to nalidixic acid. Arch. Dermatol. 109:263.
    • (1974) Arch. Dermatol , vol.109 , pp. 263
    • Burry, J.N.1
  • 31
    • 0020635049 scopus 로고
    • The effect of bacterial DNA gyrase inhibitors on DNA synthesis in mammalian mitochondria
    • Castora, F. J., Vissering, F. F., and Simpson, M. V. 1983. The effect of bacterial DNA gyrase inhibitors on DNA synthesis in mammalian mitochondria. Biochim. Biophys. Acta 740:417-127.
    • (1983) Biochim. Biophys. Acta , vol.740 , pp. 417-127
    • Castora, F.J.1    Vissering, F.F.2    Simpson, M.V.3
  • 32
    • 0026749761 scopus 로고
    • A case of destructive polyarthropathy in a 17-year-old youth following pefloxacin treatment
    • Chevalier, X., Albengres, E., Voisin, M.-C, Tillement, J.-P., and Larget-Piet, B. 1992. A case of destructive polyarthropathy in a 17-year-old youth following pefloxacin treatment. Drug Safety 7:310-314.
    • (1992) Drug Safety , vol.7 , pp. 310-314
    • Chevalier, X.1    Albengres, E.2    Voisin, M.-C.3    Tillement, J.-P.4    Larget-Piet, B.5
  • 33
    • 0000686937 scopus 로고
    • Toxicity of the quinolones
    • C. Siporin, C. L. Heifetz, and J. M. Domagala, New York: Marcel Dekker
    • Christ, W., and Lehnert, T. 1990. Toxicity of the quinolones. In The new generation of quinolones, eds. C. Siporin, C. L. Heifetz, and J. M. Domagala, pp. 165-186. New York: Marcel Dekker.
    • (1990) The New Generation of Quinolones , pp. 165-186
    • Christ, W.1    Lehnert, T.2
  • 34
    • 0023716946 scopus 로고
    • Specific toxicologic aspects of the quinolones
    • Christ, W., Lehnert, T., and Ulbrich, B. 1988. Specific toxicologic aspects of the quinolones. Rev. Infect. Dis. 10:S141-S146.
    • (1988) Rev. Infect. Dis , vol.10 , pp. S141-S146
    • Christ, W.1    Lehnert, T.2    Ulbrich, B.3
  • 35
    • 0025835787 scopus 로고
    • Quinolones in clinical use. Safety of ciprofloxacin in children: Worldwide clinical experience based on compassionate use. Emphasis on joint evaluation
    • Chysky, V., Kapila, K., Hullmann, R., Arcieri, G., Schacht, P., and Echols, R. 1991. Quinolones in clinical use. Safety of ciprofloxacin in children: Worldwide clinical experience based on compassionate use. Emphasis on joint evaluation. Infection 19:289-296.
    • (1991) Infection , vol.19 , pp. 289-296
    • Chysky, V.1    Kapila, K.2    Hullmann, R.3    Arcieri, G.4    Schacht, P.5    Echols, R.6
  • 36
    • 0027404237 scopus 로고
    • High capacity in vitro micronucleus assay for assess-ment of chromosome damage: Results with quinolone/naphthyridone antibacterials
    • Ciaravino, V., Suto, M. J., and Rheiss, J. C. 1993. High capacity in vitro micronucleus assay for assess-ment of chromosome damage: Results with quinolone/naphthyridone antibacterials. Mutât. Res. 298:227-236.
    • (1993) Mutât. Res , vol.298 , pp. 227-236
    • Ciaravino, V.1    Suto, M.J.2    Rheiss, J.C.3
  • 37
    • 0026541227 scopus 로고
    • The role of the excision and error-prone repair systems in mutagenesis by fluorinated quinolones in
    • Clerch, B., Barbé, J., and Llagostera, M. 1992. The role of the excision and error-prone repair systems in mutagenesis by fluorinated quinolones in Salmonella typhimurium. Mutât. Res. 281:207-213.
    • (1992) Salmonella Typhimurium. Mutât. Res , vol.281 , pp. 207-213
    • Clerch, B.1    Barbé, J.2    Llagostera, M.3
  • 41
    • 0024453383 scopus 로고
    • DNA topoisomerases and models of sister-chromatid exchange
    • Dillehay, L. E., Kram, D., and Williams, J. R. 1989. DNA topoisomerases and models of sister-chromatid exchange. Mutât. Res. 215:15-23.
    • (1989) Mutât. Res , vol.215 , pp. 15-23
    • Dillehay, L.E.1    Kram, D.2    Williams, J.R.3
  • 42
    • 0025772063 scopus 로고
    • General phar-macology of sparfloxacin, a new quinolone antibacterial agent. (1) Effects on the central nervous system
    • Dodo, M., Nakatsuji, K., Miura, Y., Hori, M., Furukawa, K., Oka, M., and Ito, T. 1991. General phar-macology of sparfloxacin, a new quinolone antibacterial agent. (1) Effects on the central nervous system. Ohyo Yakuri 41:147-155.
    • (1991) Ohyo Yakuri , vol.41 , pp. 147-155
    • Dodo, M.1    Nakatsuji, K.2    Miura, Y.3    Hori, M.4    Furukawa, K.5    Oka, M.6    Ito, T.7
  • 43
    • 0019206505 scopus 로고
    • Pharmacologic actions of cinoxacin on the respiratory and cardiovascular systems and smooth muscles
    • Doteuchi, M., Oka, M., and Ohuchi, T. 1980. Pharmacologic actions of cinoxacin on the respiratory and cardiovascular systems and smooth muscles. Chemotherapy 28(S-4):550-559.
    • (1980) Chemotherapy , vol.28 , pp. 550-559
    • Doteuchi, M.1    Oka, M.2    Ohuchi, T.3
  • 44
    • 0007550672 scopus 로고
    • Origin and scope of toxicology
    • C. Klaassen, M. Amdur, and J. Doull, New York: Macmillan
    • Doull, J., and Bruce, M. 1986. Origin and scope of toxicology. In Casarett and Doull’s Toxicology, 3rd ed., eds. C. Klaassen, M. Amdur, and J. Doull, pp. 3-10. New York: Macmillan.
    • (1986) Casarett and Doull’s Toxicology, 3Rd , pp. 3-10
    • Doull, J.1    Bruce, M.2
  • 45
    • 0003068439 scopus 로고
    • Hormonal control and mammalian skin gland
    • D. Muller-Schwarze and M. M. Mozell, New York: Plenum Press
    • Ebling, F.J. 1977. Hormonal control and mammalian skin gland. In Chemical signal in vertebrates, eds. D. Muller-Schwarze and M. M. Mozell, pp. 17-33. New York: Plenum Press.
    • (1977) Chemical Signal in Vertebrates , pp. 17-33
    • Ebling, F.J.1
  • 46
    • 0023686820 scopus 로고
    • Loss of antibiotic activity caused by photodegradation: In vitro studies
    • Ferguson, J., Philips, G., and McEwen, J. 1988. Loss of antibiotic activity caused by photodegradation: In vitro studies. Br. J. Dermatol. 119:550-551.
    • (1988) Br. J. Dermatol , vol.119 , pp. 550-551
    • Ferguson, J.1    Philips, G.2    McEwen, J.3
  • 47
    • 0025103581 scopus 로고
    • The mechanism of photohemolysis by photoproducts of nalidixic acid
    • Fernandez, E. B., and Cardenas, A. M. G. 1990. The mechanism of photohemolysis by photoproducts of nalidixic acid. J. Photochem. Photobiol. B4:329-333.
    • (1990) J. Photochem. Photobiol , vol.B4 , pp. 329-333
    • Fernandez, E.B.1    Cardenas, A.M.G.2
  • 48
    • 0023555153 scopus 로고
    • Phototoxicity from nalidixic acid: Oxygen-dependent photohemolysis
    • Fernandez, E. B., Cardenas, A. M. G., and Martinez, G. S. 1987. Phototoxicity from nalidixic acid: Oxygen-dependent photohemolysis. Farmaco Ed. Sci. 42:681-690.
    • (1987) Farmaco Ed. Sci , vol.42 , pp. 681-690
    • Fernandez, E.B.1    Cardenas, A.M.G.2    Martinez, G.S.3
  • 49
    • 0015945432 scopus 로고
    • Mutagenic and modificational activity of nevigramon
    • Filippova, L. M., and Yefremova, G. I. 1974. Mutagenic and modificational activity of nevigramon. Cenetika 10:165-166.
    • (1974) Cenetika , vol.10 , pp. 165-166
    • Filippova, L.M.1    Yefremova, G.I.2
  • 50
    • 84954928427 scopus 로고
    • FDA committee urges stronger warnings on Searle’s Maxaquin
    • Food and Drug Administration
    • Food and Drug Administration. 1993. FDA committee urges stronger warnings on Searle’s Maxaquin. SCRIP 1810:11-32.
    • (1993) SCRIP , pp. 11-32
  • 51
    • 0027208842 scopus 로고
    • Binding capacity of quinolones to cartilage components
    • Forster, C., Baumann-Wilschke, I., and Stahlmann, R. 1993. Binding capacity of quinolones to cartilage components. Drugs 45 suppl. 31:283-285.
    • (1993) Drugs , vol.45 , pp. 283-285
    • Forster, C.1    Baumann-Wilschke, I.2    Stahlmann, R.3
  • 52
    • 0021688414 scopus 로고
    • Prevention of granulocyte-mediated oxidant lung injury in rats by hydroxyl radical scavenger, dimethylthiourea
    • Fox, R. B. 1984. Prevention of granulocyte-mediated oxidant lung injury in rats by hydroxyl radical scavenger, dimethylthiourea. J. Clin. Invest. 74:1456-1464.
    • (1984) J. Clin. Invest , vol.74 , pp. 1456-1464
    • Fox, R.B.1
  • 53
    • 0021347749 scopus 로고
    • Disposition and metabolism of [UC]AT- 2266, II. Repeated administration
    • Fujii, T., Furukawa, H., Miyazaki, H., and Hashimoto, M. 1984. Disposition and metabolism of [UC]AT- 2266, II. Repeated administration. Chemotherapy 32(S-3): 136-141.
    • (1984) Chemotherapy , vol.32 , pp. 136-141
    • Fujii, T.1    Furukawa, H.2    Miyazaki, H.3    Hashimoto, M.4
  • 54
    • 0025271803 scopus 로고
    • Evaluation of norfloxacin in the pediatric field
    • Fujii, K., and 67 others. 1990. Evaluation of norfloxacin in the pediatric field. Ipn. I. Antibiot. 18:181-214.
    • (1990) Ipn. I. Antibiot , vol.18 , pp. 181-214
    • Fujii, K.1    67, O.2
  • 55
    • 84901356851 scopus 로고
    • Reproductive and developmental toxicity studies of sparfloxacin (2). Teratogenicity study in rats
    • Funabashi, H., Mukumoto, K., Shigematsu, K., Nishimura, K., and Ohnishi, K. 1991a. Reproductive and developmental toxicity studies of sparfloxacin (2). Teratogenicity study in rats. Yakuri to Chiryou 19:1257-1274.
    • (1991) Yakuri to Chiryou , vol.19 , pp. 1257-1274
    • Funabashi, H.1    Mukumoto, K.2    Shigematsu, K.3    Nishimura, K.4    Ohnishi, K.5
  • 56
    • 84954953227 scopus 로고
    • Reproductive and developmental toxicity studies of sparfloxacin (3). Perinatal and postnatal study in rats
    • Funabashi, H., Mukumoto, K., Imura, Y., Nishimura, K., and Ohnishi, K. 1991b. Reproductive and developmental toxicity studies of sparfloxacin (3). Perinatal and postnatal study in rats. Yakuri to Chiryou 19:1275-1289.
    • (1991) Yakuri to Chiryou , vol.19 , pp. 1275-1289
    • Funabashi, H.1    Mukumoto, K.2    Imura, Y.3    Nishimura, K.4    Ohnishi, K.5
  • 57
    • 0026823611 scopus 로고
    • Interaction of the new quinolone antibacterial agent levofloxacin with fenbufen in mice
    • Furuhama, K., Akahane, K., Tawara, K., and Takayama, S. 1992. Interaction of the new quinolone antibacterial agent levofloxacin with fenbufen in mice. Arzneim.-ForschJDrug Res. 42:406-408.
    • (1992) Arzneim.-Forschjdrug Res , vol.42 , pp. 406-408
    • Furuhama, K.1    Akahane, K.2    Tawara, K.3    Takayama, S.4
  • 58
    • 0027471191 scopus 로고
    • Safety of fleroxacin in clinical trials
    • Geddes, A. M. 1993. Safety of fleroxacin in clinical trials. Am.l. Med. 94:201S-203S.
    • (1993) Am.L. Med , vol.94 , pp. 201S-203S
    • Geddes, A.M.1
  • 59
    • 0014696888 scopus 로고
    • Mutagenic action of nalidixic acid on staphy-lococcal phage. C. R
    • German, A., Panouse-Perrin, J., and Ardouin, A. C. 1969. Mutagenic action of nalidixic acid on staphy-lococcal phage. C. R. Acad. Sci. 268:1827-1829.
    • (1969) Acad. Sci , vol.268 , pp. 1827-1829
    • German, A.1    Panouse-Perrin, J.2    Ardouin, A.C.3
  • 60
    • 0021009841 scopus 로고
    • Mechanism of photosensitization
    • Girotti, A. W. 1983. Mechanism of photosensitization. Photochem. Photobiol. 38:745-751.
    • (1983) Photochem. Photobiol , vol.38 , pp. 745-751
    • Girotti, A.W.1
  • 61
    • 0025829092 scopus 로고
    • Mechanism of quinolone mutagenicity in bacteria
    • Gocke, E. 1991. Mechanism of quinolone mutagenicity in bacteria. Mutat. Res. 248:135-143.
    • (1991) Mutat. Res , vol.248 , pp. 135-143
    • Gocke, E.1
  • 62
    • 0022438848 scopus 로고
    • Models of hepatocarcinogenesis in the rats- Contrast and comparisons
    • Goldsworthy, T. L., Hanigan, M., and Pitot, H. 1986. Models of hepatocarcinogenesis in the rats- Contrast and comparisons. CRC Crit. Rev. Toxicol. 17:61-89.
    • (1986) CRC Crit. Rev. Toxicol , vol.17 , pp. 61-89
    • Goldsworthy, T.L.1    Hanigan, M.2    Pitot, H.3
  • 63
    • 0018568255 scopus 로고
    • Juvenile canine drug-induced arthropathy: Clinicopathological studies on articular lesions caused by oxolinic and pipemidic acids
    • Gough, A., Barsoum, N. J., Mitchell, L., McGuire, E. J., and De La Iglesia, F. A. 1979. Juvenile canine drug-induced arthropathy: Clinicopathological studies on articular lesions caused by oxolinic and pipemidic acids. Toxicol. Appl. Pharmacol. 51:177-187.
    • (1979) Toxicol. Appl. Pharmacol , vol.51 , pp. 177-187
    • Gough, A.1    Barsoum, N.J.2    Mitchell, L.3    McGuire, E.J.4    De La Iglesia, F.A.5
  • 64
    • 0001743848 scopus 로고
    • Adverse effects of the fluoroquinolones
    • Halkin, H. 1988. Adverse effects of the fluoroquinolones. Rev. Infect. Dis. 10(suppl.):S258-S261.
    • (1988) Rev. Infect. Dis , vol.10 , pp. S258-S261
    • Halkin, H.1
  • 65
    • 0027210004 scopus 로고
    • Function of SOS process in repair of DNA damage induced by modern 4-quinolones
    • Haward, B. M., Pinney, R. J., and Smith, J. T. 1993. Function of SOS process in repair of DNA damage induced by modern 4-quinolones. J. Pharm. Pharmacol. 45:658-662.
    • (1993) J. Pharm. Pharmacol , vol.45 , pp. 658-662
    • Haward, B.M.1    Pinney, R.J.2    Smith, J.T.3
  • 69
    • 0024515242 scopus 로고
    • Adverse drug interactions between pyridonecar-boxylic acids and nonsteroidal antiinflammatory drugs: Convulsion after oral or intracerebral administration in mice
    • Hirai, S., Tanaka, K., Makino, S., and Narita, H. 1989b. Adverse drug interactions between pyridonecar-boxylic acids and nonsteroidal antiinflammatory drugs: Convulsion after oral or intracerebral administration in mice. Yakugaku Zasshi 109:119-126.
    • (1989) Yakugaku Zasshi , vol.109 , pp. 119-126
    • Hirai, S.1    Tanaka, K.2    Makino, S.3    Narita, H.4
  • 70
    • 0024422633 scopus 로고
    • Genetic profile of a nalidixic acid analog: A model for the mechanism of sister chromatid exchange induction
    • Holden, H. E., Barett, J. F., Huntington, C. M., Muehlbauer, P. A., and Wahrenburg, M. G. 1989. Genetic profile of a nalidixic acid analog: A model for the mechanism of sister chromatid exchange induction. Environ. Mol. Mutagen. 13:238-252.
    • (1989) Environ. Mol. Mutagen , vol.13 , pp. 238-252
    • Holden, H.E.1    Barett, J.F.2    Huntington, C.M.3    Muehlbauer, P.A.4    Wahrenburg, M.G.5
  • 71
    • 0025817691 scopus 로고
    • A study on convulsive effects of sparfloxacin with or without non-steroidal anti-inflammatory drugs
    • Hori, S., Shimada, J., Shiba, K., Yoshida, M., Saito, A., and Sakai, O. 1991. A study on convulsive effects of sparfloxacin with or without non-steroidal anti-inflammatory drugs. Chemotherapy 39:161-166.
    • (1991) Chemotherapy , vol.39 , pp. 161-166
    • Hori, S.1    Shimada, J.2    Shiba, K.3    Yoshida, M.4    Saito, A.5    Sakai, O.6
  • 72
    • 0026065494 scopus 로고
    • Significance of the methyl group on the oxazine ring of ofloxacin derivatives in the inhibition of bacterial and mammalian type II topoisomerases
    • Hoshino, K., Sato, K., Akahane, K., Yoshida, A., Hayakawa, I., Sato, M., Une, T., and Osada, Y. 1991. Significance of the methyl group on the oxazine ring of ofloxacin derivatives in the inhibition of bacterial and mammalian type II topoisomerases. Antimicrob. Agents Chemother. 35:309-312.
    • (1991) Antimicrob. Agents Chemother , vol.35 , pp. 309-312
    • Hoshino, K.1    Sato, K.2    Akahane, K.3    Yoshida, A.4    Hayakawa, I.5    Sato, M.6    Une, T.7    Osada, Y.8
  • 74
    • 0021207993 scopus 로고
    • Rapid detection of DNA-damaging agents using repair-deficient CHO cells
    • Hoy, C. A., Salazar, E. P., and Thompson, L. H. 1984. Rapid detection of DNA-damaging agents using repair-deficient CHO cells. Mutat. Res. 130:321-332.
    • (1984) Mutat. Res , vol.130 , pp. 321-332
    • Hoy, C.A.1    Salazar, E.P.2    Thompson, L.H.3
  • 75
    • 0022538665 scopus 로고
    • Effect of 4-quinolones and novobiocin on calf thymus DNA polymerase complex, topoisomerase I and II, and growth of mam-malian lymphoblast
    • Hussy, P., Maas, G., Tummler, B., Grosse, F., and Schamburg, U. 1986. Effect of 4-quinolones and novobiocin on calf thymus DNA polymerase complex, topoisomerase I and II, and growth of mam-malian lymphoblast. Antimicrob. Agents Chemother. 29:1073-1078.
    • (1986) Antimicrob. Agents Chemother , vol.29 , pp. 1073-1078
    • Hussy, P.1    Maas, G.2    Tummler, B.3    Grosse, F.4    Schamburg, U.5
  • 78
    • 0017587373 scopus 로고
    • Arthropathy induced by antibacterial fused N-alkyl-4 pyridone-3-carboxylic acid
    • Ingham, B., Brentnall, D. W., Dale, E. A., and McFadzean, J. A. 1977. Arthropathy induced by antibacterial fused N-alkyl-4 pyridone-3-carboxylic acid. Toxicol. Lett. 1:21-26.
    • (1977) Toxicol. Lett , vol.1 , pp. 21-26
    • Ingham, B.1    Brentnall, D.W.2    Dale, E.A.3    McFadzean, J.A.4
  • 79
    • 0019857502 scopus 로고
    • The mutagenicity of AM-715 in vitro
    • Irikura, T., and Hosomi, J. 1981. The mutagenicity of AM-715 in vitro. Chemotherapy 29(S-4):938-945.
    • (1981) Chemotherapy , vol.29 , pp. 938-945
    • Irikura, T.1    Hosomi, J.2
  • 80
    • 0019791695 scopus 로고
    • Toxicological study of AM-715. (4) Chronic toxicity study in rats
    • Irikura, T., Sugimoto, T., Ajima, H., and Tsuchiya, T. 1981a. Toxicological study of AM-715. (4) Chronic toxicity study in rats. Chemotherapy 29(S-4):829-848.
    • (1981) Chemotherapy , vol.29 , Issue.S-4 , pp. 829-848
    • Irikura, T.1    Sugimoto, T.2    Ajima, H.3    Tsuchiya, T.4
  • 81
    • 0019816465 scopus 로고
    • Toxicological study of AM-715. (5) Chronic toxicity study in dogs
    • Irikura, T., Sugimoto, T., Imai, S., Ikeda, T., Tanase, H., and Kanda, K. 1981b. Toxicological study of AM-715. (5) Chronic toxicity study in dogs. Chemotherapy 29(S-4):849-885.
    • (1981) Chemotherapy , vol.29 , Issue.S-4 , pp. 849-885
    • Irikura, T.1    Sugimoto, T.2    Imai, S.3    Ikeda, T.4    Tanase, H.5    Kanda, K.6
  • 82
    • 0019825399 scopus 로고
    • Reproduction studies of AM-715. (1) Fertility study
    • Irikura, T., Suzuki, H., and Sugimoto, T. 1981c. Reproduction studies of AM-715. (1) Fertility study. Chemotherapy 29(S-4):886-894.
    • (1981) Chemotherapy , vol.29 , Issue.S-4 , pp. 886-894
    • Irikura, T.1    Suzuki, H.2    Sugimoto, T.3
  • 83
    • 0019851569 scopus 로고
    • D. Reproduction studies of AM-715 in mice. (2) Teratological study
    • Irikura, T., Suzuki, H., and Sugimoto, T. 1981 d. Reproduction studies of AM-715 in mice. (2) Teratological study. Chemotherapy 29(S-4):895-914.
    • (1981) Chemotherapy , vol.29 , pp. 895-914
    • Irikura, T.1    Suzuki, H.2    Sugimoto, T.3
  • 85
    • 0019849821 scopus 로고
    • F. Reproduction studies of AM-715 in mice. (3) Perinatal and postnatal study
    • Irikura, T., Suzuki, H., and Sugimoto, T. 1981 f. Reproduction studies of AM-715 in mice. (3) Perinatal and postnatal study. Chemotherapy 29(S-4):9T5-931.
    • (1981) Chemotherapy , vol.29 , pp. 9T5-931
    • Irikura, T.1    Suzuki, H.2    Sugimoto, T.3
  • 87
    • 0019846691 scopus 로고
    • Mutagenicity studies of AM-715 in animals
    • Irikura, T., Suzuki, H., and Sugimoto, T. 1981 h. Mutagenicity studies of AM-715 in animals. Chemotherapy 29(S-4):932-937.
    • (1981) Chemotherapy , vol.29 , pp. 932-937
    • Irikura, T.1    Suzuki, H.2    Sugimoto, T.3
  • 88
    • 84996012193 scopus 로고
    • Pharmacological studies on piromidic acid
    • Isozaki, T., and Matsuno, Y. 1971. Pharmacological studies on piromidic acid. Chemotherapy 19:394403.
    • (1971) Chemotherapy , pp. 19
    • Isozaki, T.1    Matsuno, Y.2
  • 89
    • 0019844448 scopus 로고
    • In vitro and in vivo antibacterial of AM-715
    • Ito, A., Hirai, K., Inoue, M., and Mitsuhashi, S. 1981. In vitro and in vivo antibacterial of AM-715. Chemotherapy 29(S-4): 1-11.
    • (1981) Chemotherapy , vol.29 , pp. 1-11
    • Ito, A.1    Hirai, K.2    Inoue, M.3    Mitsuhashi, S.4
  • 90
    • 0027787941 scopus 로고
    • A,-Adrenoceptor-blocking activity of ofloxacin and ciprofloxacin in isolated vascular smooth muscles
    • Ito, K., Murakami, K., and Tamura, K. 1993. a,-Adrenoceptor-blocking activity of ofloxacin and ciprofloxacin in isolated vascular smooth muscles. Arch. Int. Pharmacodyn. Ther. 325:86-95.
    • (1993) Arch. Int. Pharmacodyn. Ther , vol.325 , pp. 86-95
    • Ito, K.1    Murakami, K.2    Tamura, K.3
  • 91
    • 0023858438 scopus 로고
    • Enhancing effect of various hepatocarcinogens on induction of preneoplastic glutathione 5-transferase placental form positive foci in rats-An approach for new medium-term bioassay system
    • Ito, N., Tsuda, H., Tatematsu, M., Inoue, T., Tagawa, Y., Aoki, T., Uwagawa, S., Kagawa, M., Ogiso, T., Masui, T., Imaida, K., Fukushima, S., and Asamoto, M. 1988. Enhancing effect of various hepatocarcinogens on induction of preneoplastic glutathione 5-transferase placental form positive foci in rats-An approach for new medium-term bioassay system. Carcinogenesis 9:387-394.
    • (1988) Carcinogenesis , vol.9 , pp. 387-394
    • Ito, N.1    Tsuda, H.2    Tatematsu, M.3    Inoue, T.4    Tagawa, Y.5    Aoki, T.6    Uwagawa, S.7    Kagawa, M.8    Ogiso, T.9    Masui, T.10    Imaida, K.11    Fukushima, S.12    Asamoto, M.13
  • 92
    • 0015419182 scopus 로고
    • In vitro and host-mediated “rec-assay” procedure for screening chemical mutagens; and phloxine, a mutagenic red dye detected
    • Kada, T., Tutikawa, K., and Sadaie, Y. 1972. In vitro and host-mediated “rec-assay” procedure for screening chemical mutagens; and phloxine, a mutagenic red dye detected. Mutat. Res. 16:165-174.
    • (1972) Mutat. Res , vol.16 , pp. 165-174
    • Kada, T.1    Tutikawa, K.2    Sadaie, Y.3
  • 93
    • 0026832582 scopus 로고
    • Effects of the new quinolone antibacterial agent levofloxacin on multiple organ carcinogenesis initiated with wide-spectrum carcinogens in rats
    • Kajimura, T., Tojo, H., Kudo, G., Yamada, M., Donon, S., Nomura, M., and Takayama, S. 1992. Effects of the new quinolone antibacterial agent levofloxacin on multiple organ carcinogenesis initiated with wide-spectrum carcinogens in rats. Arzneim.-ForschJDrug Res. 42:390-395.
    • (1992) Arzneim.-Forschjdrug Res , vol.42 , pp. 390-395
    • Kajimura, T.1    Tojo, H.2    Kudo, G.3    Yamada, M.4    Donon, S.5    Nomura, M.6    Takayama, S.7
  • 94
    • 0023805987 scopus 로고
    • Morphological investigation of cavity formation in articular cartilage induced by ofloxacin in rats
    • Kato, M., and Onodera, T. 1988a. Morphological investigation of cavity formation in articular cartilage induced by ofloxacin in rats. Fundam. Appl. Toxicol. 11:110-119.
    • (1988) Fundam. Appl. Toxicol , vol.11 , pp. 110-119
    • Kato, M.1    Onodera, T.2
  • 95
    • 0023785938 scopus 로고
    • Effect of ofloxacin on the uptake of [3H]thymidine by articular carti-lage cells in the rat
    • Kato, M., and Onodera, T. 1988b. Effect of ofloxacin on the uptake of [3H]thymidine by articular carti-lage cells in the rat. Toxicol. Lett. 44:131-142.
    • (1988) Toxicol. Lett , vol.44 , pp. 131-142
    • Kato, M.1    Onodera, T.2
  • 96
    • 0023707034 scopus 로고
    • Morphological investigation of osteochondrosis induced by ofloxacin in rats
    • Kato, M., and Onodera, T. 1988c. Morphological investigation of osteochondrosis induced by ofloxacin in rats. Fundam. Appl. Toxicol. 11:120-131.
    • (1988) Fundam. Appl. Toxicol , vol.11 , pp. 120-131
    • Kato, M.1    Onodera, T.2
  • 97
    • 0021447821 scopus 로고
    • Hematoporphyrin and HPD: Photophysics, photochemistry and phototherapy
    • Kessel, D. 1984. Hematoporphyrin and HPD: Photophysics, photochemistry and phototherapy. Photochem. Photobiol. 39:851-859.
    • (1984) Photochem. Photobiol , vol.39 , pp. 851-859
    • Kessel, D.1
  • 100
    • 0019189329 scopus 로고
    • Sister-chromatid exchanges in children treated with nalidixic acid
    • Kowalczyk, J. 1980. Sister-chromatid exchanges in children treated with nalidixic acid. Mutat. Res. 77:371-375.
    • (1980) Mutat. Res , vol.77 , pp. 371-375
    • Kowalczyk, J.1
  • 101
    • 0024469167 scopus 로고
    • Quinolones and coumarins eliminate chloroplasts from Euglena gracilis. Antimicrob
    • Krajcovic, J., Ebringer, L., and Polonyi, J. 1989. Quinolones and coumarins eliminate chloroplasts from Euglena gracilis. Antimicrob. Agents Chemother. 33:1883-1889.
    • (1989) Agents Chemother , vol.33 , pp. 1883-1889
    • Krajcovic, J.1    Ebringer, L.2    Polonyi, J.3
  • 102
    • 84954928464 scopus 로고
    • Two cases of drug eruption induced by enoxacin-A study of cross-reactivity between pyridonecarboxylic acids
    • Kurosawa, T., and Ikezawa, Z. 1992. Two cases of drug eruption induced by enoxacin-A study of cross-reactivity between pyridonecarboxylic acids. Rinsho-Hifu 46:929-933.
    • (1992) Rinsho-Hifu , vol.46 , pp. 929-933
    • Kurosawa, T.1    Ikezawa, Z.2
  • 103
    • 0025905060 scopus 로고
    • Fluoroquinolones in the treatment of cystic fibrosis: A critical appraisal
    • LeBel, M. 1991. Fluoroquinolones in the treatment of cystic fibrosis: A critical appraisal. Eur. J. Clin. Microbiol. Infect. Dis. 10:316-324.
    • (1991) Eur. J. Clin. Microbiol. Infect. Dis , vol.10 , pp. 316-324
    • Lebel, M.1
  • 104
    • 0022392831 scopus 로고
    • Investigations into the reported ability of cimetidine to initiate UDS in rat hepatocyte primary culture
    • Lefever, P. A., and Ashby, B. J. 1985. Investigations into the reported ability of cimetidine to initiate UDS in rat hepatocyte primary culture. Environ. Mutagen. 7:833-837.
    • (1985) Environ. Mutagen , vol.7 , pp. 833-837
    • Lefever, P.A.1    Ashby, B.J.2
  • 105
    • 0025765013 scopus 로고
    • Antibacterial activity of lomefloxacin./
    • Leigh, D. A., Tait, S., and Walsh, B. 1991. Antibacterial activity of lomefloxacin./. Antimicrob. Chemother. 27:589-598.
    • (1991) Antimicrob. Chemother , vol.27 , pp. 589-598
    • Leigh, D.A.1    Tait, S.2    Walsh, B.3
  • 106
    • 33947476615 scopus 로고
    • 1, 8-Naphthyridine derivatives: A new class of chemotherapeutic agents
    • Lesher, G., Froelich, E., Gruet, M., Bailey, J., and Brundage, R. 1962. 1, 8-Naphthyridine derivatives: A new class of chemotherapeutic agents. J. Med. Pharm. Chem. 5:1063-1068.
    • (1962) J. Med. Pharm. Chem , vol.5 , pp. 1063-1068
    • Lesher, G.1    Froelich, E.2    Gruet, M.3    Bailey, J.4    Brundage, R.5
  • 107
    • 0000820621 scopus 로고
    • Spontaneous and mutagen-induced deletions: Mechanistic studies in Salmonella tester strain TA102
    • Levin, D. E., Marnett, L. J., and Ames, B. N. 1984. Spontaneous and mutagen-induced deletions: Mechanistic studies in Salmonella tester strain TA102. Proc. Natl. Acad. Sci. USA 81:4457-4461.
    • (1984) Proc. Natl. Acad. Sci. USA , vol.81 , pp. 4457-4461
    • Levin, D.E.1    Marnett, L.J.2    Ames, B.N.3
  • 108
    • 0020326895 scopus 로고
    • The role of estrogen and progesterone in the con-trol of preputial gland sex attractant odors in the female rat
    • Lucas, P. D., Donohoe, S. M., and Thody, A. J. 1982. The role of estrogen and progesterone in the con-trol of preputial gland sex attractant odors in the female rat. Physiol. Behav. 8:601-607.
    • (1982) Physiol. Behav , vol.8 , pp. 601-607
    • Lucas, P.D.1    Donohoe, S.M.2    Thody, A.J.3
  • 110
    • 0027411719 scopus 로고
    • Activity of quinolones in the Ames Salmonella TA102 mutagenicity test and other bacterial genotoxicity assays
    • Mamber, S. W., Kolek, B., Brookshire, K. W., Bonner, D. P., and Fung-Tomc, J. 1993. Activity of quinolones in the Ames Salmonella TA102 mutagenicity test and other bacterial genotoxicity assays. Antimicrob. Agents Chemother. 37:213-217.
    • (1993) Antimicrob. Agents Chemother , vol.37 , pp. 213-217
    • Mamber, S.W.1    Kolek, B.2    Brookshire, K.W.3    Bonner, D.P.4    Fung-Tomc, J.5
  • 112
    • 0016699515 scopus 로고
    • Pharmacological studies on pipemidic acid
    • Matsuno, Y., Sohji, Y., and Shimizu, M. 1975. Pharmacological studies on pipemidic acid. Chemo-therapy 23:2671-2684.
    • (1975) Chemo-Therapy , vol.23 , pp. 2671-2684
    • Matsuno, Y.1    Sohji, Y.2    Shimizu, M.3
  • 113
    • 0021347750 scopus 로고
    • General pharmacological properties of AT-2266
    • Matsuno, Y., Taira, N., and Kadokawa, T. 1984. General pharmacological properties of AT-2266. Chemotherapy 32(S-3):164-184.
    • (1984) Chemotherapy , vol.32 , pp. 164-184
    • Matsuno, Y.1    Taira, N.2    Kadokawa, T.3
  • 114
    • 0023766491 scopus 로고
    • Evaluation of the DNA-damaging and mutagenic activity of oxalinic acid and pipemidic acids by the granuloma pouch assay
    • Maura, A., and Pino, A. 1988. Evaluation of the DNA-damaging and mutagenic activity of oxalinic acid and pipemidic acids by the granuloma pouch assay. Mutagenesis 3:397-401.
    • (1988) Mutagenesis , vol.3 , pp. 397-401
    • Maura, A.1    Pino, A.2
  • 115
    • 0025788250 scopus 로고
    • Induction of sperm abnormalities in mice by norfloxacin
    • Maura, A., and Pino, A. 1991. Induction of sperm abnormalities in mice by norfloxacin. Mutat. Res. 264:197-200.
    • (1991) Mutat. Res , vol.264 , pp. 197-200
    • Maura, A.1    Pino, A.2
  • 116
    • 0018878838 scopus 로고
    • Non-mutagenic genotoxigens: Novobiocin and nalidixic acid, 2 inhibitors of DNA gyrase
    • McCoy, E. C., Petrullo, L. A., and Rosenkranz, H. S. 1980. Non-mutagenic genotoxigens: Novobiocin and nalidixic acid, 2 inhibitors of DNA gyrase. Mutat. Res. 79:33-43.
    • (1980) Mutat. Res , vol.79 , pp. 33-43
    • McCoy, E.C.1    Petrullo, L.A.2    Rosenkranz, H.S.3
  • 117
    • 0023610696 scopus 로고
    • Effects of quinolone antibiotics in test for genotoxicity
    • McQueen, C. A., and Williams, G. M. 1987. Effects of quinolone antibiotics in test for genotoxicity. Am. I. Med. 82(suppl. 4A):94-96.
    • (1987) Am. I. Med , vol.82 , pp. 94-96
    • McQueen, C.A.1    Williams, G.M.2
  • 118
    • 0025786801 scopus 로고
    • Study of potential in vitro and in vivo genotoxicity in hepatocytes of quinolone antibiotics
    • McQueen, C. A., Way, B. M., Queener, S. M., Schluter, G., and Williams, G. A. 1991. Study of potential in vitro and in vivo genotoxicity in hepatocytes of quinolone antibiotics. Toxicol. Appl. Pharmacol. 111:255-262.
    • (1991) Toxicol. Appl. Pharmacol , vol.111 , pp. 255-262
    • McQueen, C.A.1    Way, B.M.2    Queener, S.M.3    Schluter, G.4    Williams, G.A.5
  • 119
    • 7844248253 scopus 로고
    • Ministry of Health and Welfare, Pharmaceutical Affairs Bureau, Tokyo, Public notification
    • Ministry of Health and Welfare, Pharmaceutical Affairs Bureau, Tokyo. 1986. Drug Side Effect Information No. 81 (Public notification).
    • (1986) Drug Side Effect Information No. 81
  • 121
    • 0023238896 scopus 로고
    • Ofloxacin. A review of its antibacterial activity, phar-macokinetic properties and therapeutic use
    • Monk, J. P., and Campoli-Richards, D. M. 1987. Ofloxacin. A review of its antibacterial activity, phar-macokinetic properties and therapeutic use. Drugs 33:346-391.
    • (1987) Drugs , vol.33 , pp. 346-391
    • Monk, J.P.1    Campoli-Richards, D.M.2
  • 122
    • 0021308304 scopus 로고
    • Photosensitization by drugs: Nalidixic and oxolinic acids
    • Moore, D. E., Hemmens, V. J., and Yip, H. 1984. Photosensitization by drugs: Nalidixic and oxolinic acids. Photochem. Photobiol. 39:57-61.
    • (1984) Photochem. Photobiol , vol.39 , pp. 57-61
    • Moore, D.E.1    Hemmens, V.J.2    Yip, H.3
  • 124
    • 85004281896 scopus 로고
    • General pharma-cology of NY-198 I. Effects on the central nervous system, respiration and cardiovascular system
    • Morikawa, K., Hashimoto, S., Iwanaga, Y., Yamauchi, T., and Yamazaki, M. 1988a. General pharma-cology of NY-198 I. Effects on the central nervous system, respiration and cardiovascular system. Chemotherapy 36(S-2):265-283.
    • (1988) Chemotherapy , vol.36 , pp. 265-283
    • Morikawa, K.1    Hashimoto, S.2    Iwanaga, Y.3    Yamauchi, T.4    Yamazaki, M.5
  • 125
    • 85004203944 scopus 로고
    • General pharmacology of NY-198 II. Effects on the autonomic nervous system, peripheral nervous system and others
    • Morikawa, K., Hashimoto, S., Iwanaga, Y., Makino, E., and Yamazaki, M. 1988b. General pharmacology of NY-198 II. Effects on the autonomic nervous system, peripheral nervous system and others. Chemotherapy 36(S-2):284-299.
    • (1988) Chemotherapy , vol.36 , pp. 284-299
    • Morikawa, K.1    Hashimoto, S.2    Iwanaga, Y.3    Makino, E.4    Yamazaki, M.5
  • 126
    • 0022610088 scopus 로고
    • Drug-induced photosensitivity: Phototoxic and photoallergic reactions-A few molecular aspects
    • Morliere, P. 1986. Drug-induced photosensitivity: Phototoxic and photoallergic reactions-A few molecular aspects. Biochimie 68:849-855.
    • (1986) Biochimie , vol.68 , pp. 849-855
    • Morliere, P.1
  • 128
    • 0027393512 scopus 로고
    • Ciprofloxacin: Mammalian DNA topoisomerase type II poison in vivo
    • Mukherjee, A., Sen, S., and Agarwal, K. 1993. Ciprofloxacin: Mammalian DNA topoisomerase type II poison in vivo. Mutat. Res. 301:87-92.
    • (1993) Mutat. Res , vol.301 , pp. 87-92
    • Mukherjee, A.1    Sen, S.2    Agarwal, K.3
  • 129
    • 0019860932 scopus 로고
    • Studies on absorption, distribution and excretion of AM-715 in animals by bioassay method
    • Murayama, S., Hirai, K., Ito, A., Abe, Y., and Irikura, T. 1981. Studies on absorption, distribution and excretion of AM-715 in animals by bioassay method. Chemotherapy 29(S-4):98-104.
    • (1981) Chemotherapy , vol.29 , pp. 98-104
    • Murayama, S.1    Hirai, K.2    Ito, A.3    Abe, Y.4    Irikura, T.5
  • 130
    • 0026584475 scopus 로고
    • Central stimulating effect of the combination of the new quinolone group of antimicrobials and nonsteroidal anti-inflammatory drugs in mice
    • Murayama, S., Hara, Y., Ally, A., Suzuki, T., and Tamagawa, M. 1992. Central stimulating effect of the combination of the new quinolone group of antimicrobials and nonsteroidal anti-inflammatory drugs in mice. Folia Pharmacol. Jpn. 99:13-18.
    • (1992) Folia Pharmacol. Jpn , vol.99 , pp. 13-18
    • Murayama, S.1    Hara, Y.2    Ally, A.3    Suzuki, T.4    Tamagawa, M.5
  • 131
    • 0019783737 scopus 로고
    • Studies on the fate of, 4C-labelled AM- 715
    • Nagatsu, Y., Endo, K., and Irikura, T. 1981. Studies on the fate of, 4C-labelled AM- 715. Chemotherapy 29(S-4): 105-118.
    • (1981) Chemotherapy , vol.29 , pp. 105-118
    • Nagatsu, Y.1    Endo, K.2    Irikura, T.3
  • 133
    • 0025802726 scopus 로고
    • General pharmacology of sparfloxacin, a new quinolone antibacterial agent. (2) Effects on respiratory, cardiovascular and autonomic nervous system functions
    • Nakatsuji, K., Kii, Y., Miura, Y., and Ito, T. 1991. General pharmacology of sparfloxacin, a new quinolone antibacterial agent. (2) Effects on respiratory, cardiovascular and autonomic nervous system functions. Ohyo Yakuri 41:157-164.
    • (1991) Ohyo Yakuri , vol.41 , pp. 157-164
    • Nakatsuji, K.1    Kii, Y.2    Miura, Y.3    Ito, T.4
  • 134
    • 0021359592 scopus 로고
    • Absorption, dis-tribution, excretion and metabolism of AT-2266 in experimental animals
    • Nakamura, S., Kurobe, N., Kashimoto, S., Ohue, T., Takase, Y., and Shimizu, M. 1984. Absorption, dis-tribution, excretion and metabolism of AT-2266 in experimental animals. Chemotherapy 32(S-3): 86-94.
    • (1984) Chemotherapy , vol.32 , pp. 86-94
    • Nakamura, S.1    Kurobe, N.2    Kashimoto, S.3    Ohue, T.4    Takase, Y.5    Shimizu, M.6
  • 135
    • 84954945801 scopus 로고
    • Quinolone antimicrobial agents from the view point of clinical pharmacodynamics
    • Y. Ueda, K. Shimizu, M. Konno, and H. Matsumoto, Tokyo: Life Science
    • Nakazima, M., and Uematsu, T. 1991. Quinolone antimicrobial agents from the view point of clinical pharmacodynamics. In Quinolone antimicrobial agents, eds. Y. Ueda, K. Shimizu, M. Konno, and H. Matsumoto, pp. 99-106. Tokyo: Life Science.
    • (1991) Quinolone Antimicrobial Agents , pp. 99-106
    • Nakazima, M.1    Uematsu, T.2
  • 136
    • 0026042053 scopus 로고
    • Enhanced entry of ciprofloxacin into the rat central nervous system induced by fenbufen
    • Naora, K., Katagiri, Y., Ichikawa, N., Hayashibara, M., and Iwamoto, K. 1991. Enhanced entry of ciprofloxacin into the rat central nervous system induced by fenbufen. J. Pharmacol. Exp. Ther. 258:1033-1037.
    • (1991) J. Pharmacol. Exp. Ther , vol.258 , pp. 1033-1037
    • Naora, K.1    Katagiri, Y.2    Ichikawa, N.3    Hayashibara, M.4    Iwamoto, K.5
  • 137
    • 0017197772 scopus 로고
    • Effect of testosterone propionate on the ultra-structure of preputial gland in the rat
    • Nickerson, P. A., Freman, J. J., and Brownie, A. C. 1976. Effect of testosterone propionate on the ultra-structure of preputial gland in the rat. Acta Anat. 94:481-489.
    • (1976) Acta Anat , vol.94 , pp. 481-489
    • Nickerson, P.A.1    Freman, J.J.2    Brownie, A.C.3
  • 139
    • 0021349011 scopus 로고
    • Reproduction studies of AT-2266. (5) Teratogenicity study in dogs
    • Nishimura, K., Mukumoto, K., Terada, Y., Takenaka, H., and Yoshida, K. 1984a. Reproduction studies of AT-2266. (5) Teratogenicity study in dogs. Chemotherapy 32(S-3):327-333.
    • (1984) Chemotherapy , vol.32 , pp. 327-333
    • Nishimura, K.1    Mukumoto, K.2    Terada, Y.3    Takenaka, H.4    Yoshida, K.5
  • 140
  • 143
    • 0025869379 scopus 로고
    • Side-effects of quinolones: Comparisons between quinolones and other antibiotics
    • Norrby, S. R. 1991. Side-effects of quinolones: Comparisons between quinolones and other antibiotics. Eur. J. Clin. Microbiol. Infect. Dis. 10:378-383.
    • (1991) Eur. J. Clin. Microbiol. Infect. Dis , vol.10 , pp. 378-383
    • Norrby, S.R.1
  • 144
    • 0025809759 scopus 로고
    • Neuro excitability of spafloxacin, a novel quinolone antibacterial drug, in combination with nonsteroidal anti-inflammatory drugs
    • Nozaki, M., Tanaka, K., Takeda, N., Niwa, M., Kohno, Kobayashi, M., and Tsurumi, K. 1991. Neuro excitability of spafloxacin, a novel quinolone antibacterial drug, in combination with nonsteroidal anti-inflammatory drugs. Chemotherapy 39:167-174.
    • (1991) Chemotherapy , vol.39 , pp. 167-174
    • Nozaki, M.1    Tanaka, K.2    Takeda, N.3    Niwa, M.4    Kohno Kobayashi, M.5    Tsurumi, K.6
  • 146
    • 0019809965 scopus 로고
    • Pharmacological studies on AM-715: (I) Influences of AM-715 on central nervous system, peripheral nervous system and smooth muscle organs
    • Ohkubo, H., Segawa, M., Hirayama, T., and Nishino, K. 1981a. Pharmacological studies on AM-715: (I) Influences of AM-715 on central nervous system, peripheral nervous system and smooth muscle organs. Chemotherapy 29(S-4):965-984.
    • (1981) Chemotherapy , vol.29 , pp. 965-984
    • Ohkubo, H.1    Segawa, M.2    Hirayama, T.3    Nishino, K.4
  • 147
    • 0019851570 scopus 로고
    • Pharmacological studies on AM-715: (II) Influences of AM-715 on respiratory and cardiovascular system, exocrine and urinary system, and others
    • Ohkubo, H., Segawa, M., Hirayama, T., and Nishino, K. 1981b. Pharmacological studies on AM-715: (II) Influences of AM-715 on respiratory and cardiovascular system, exocrine and urinary system, and others. Chemotherapy 29(S-41):985-1001.
    • (1981) Chemotherapy , vol.29 , pp. 985-1001
    • Ohkubo, H.1    Segawa, M.2    Hirayama, T.3    Nishino, K.4
  • 148
    • 0026664722 scopus 로고
    • Two cases of photosensitive dermatitis induced by lomefloxacin
    • Oyama, S., Inasaka, H., Teramura, M., Sugiura, K., and Ueda, H. 1992. Two cases of photosensitive dermatitis induced by lomefloxacin. Hifu 34:457-461.
    • (1992) Hifu , vol.34 , pp. 457-461
    • Oyama, S.1    Inasaka, H.2    Teramura, M.3    Sugiura, K.4    Ueda, H.5
  • 149
    • 0026030235 scopus 로고
    • Clinical features and management of adverse effects of quinolone antibacterials
    • Paton, J. H., and Reeves, D. S. 1991. Clinical features and management of adverse effects of quinolone antibacterials. Drug Safety 6:8-27.
    • (1991) Drug Safety , vol.6 , pp. 8-27
    • Paton, J.H.1    Reeves, D.S.2
  • 150
    • 0016700883 scopus 로고
    • Comparative enhancing effect of phénobarbi-tal, diphenylhydantoin, and dichlorodiphenyl-trichloroethane on 2-acetyl-aminofluorene induced hepatic tumorigenesis in the rats
    • Peraino, C., Fry, R., Staffeldt, E., and Christopher, J. 1975. Comparative enhancing effect of phénobarbi-tal, diphenylhydantoin, and dichlorodiphenyl-trichloroethane on 2-acetyl-aminofluorene induced hepatic tumorigenesis in the rats. Cancer Res. 35:2884-2890.
    • (1975) Cancer Res , vol.35 , pp. 2884-2890
    • Peraino, C.1    Fry, R.2    Staffeldt, E.3    Christopher, J.4
  • 151
    • 0024831871 scopus 로고
    • Tolerance articu-laire de la pefloxacine et de l’ofloxacine chez les enfants et adolescents atteints de muscoviscidose
    • Pertuiset, E., Lenoir, G., Jehanne, M., Douchain, F., Guillot, M., and Menkes, F. 1989. Tolerance articu-laire de la pefloxacine et de l’ofloxacine chez les enfants et adolescents atteints de muscoviscidose. Rev. Rhum. 56:735-740.
    • (1989) Rev. Rhum , vol.56 , pp. 735-740
    • Pertuiset, E.1    Lenoir, G.2    Jehanne, M.3    Douchain, F.4    Guillot, M.5    Menkes, F.6
  • 152
    • 0025695544 scopus 로고
    • The loss of antibiotic activity of ciprofloxacin by photodegradation
    • Phillips, G., Johnson, B. E., and Ferguson, J. 1990. The loss of antibiotic activity of ciprofloxacin by photodegradation. j. Antimicrob. Chemother. 26:783-789.
    • (1990) J. Antimicrob. Chemother , vol.26 , pp. 783-789
    • Phillips, G.1    Johnson, B.E.2    Ferguson, J.3
  • 153
    • 0023579802 scopus 로고
    • Bacterial mutagenicity and the 4-quinolones
    • Phillips, I. 1987. Bacterial mutagenicity and the 4-quinolones. I. Antimicrob. Chemother. 20:771-773.
    • (1987) I. Antimicrob. Chemother , vol.20 , pp. 771-773
    • Phillips, I.1
  • 155
    • 84954972220 scopus 로고
    • Physicians’ Desk Reference, Also Norfloxacin. 47th ed., pp. 1482-1483. Montvale, NJ: Medical Economics
    • Physicians’ Desk Reference. 1993. Ciprofloxacin. 47th ed., pp. 1636-1639. Also Norfloxacin. 47th ed., pp. 1482-1483. Montvale, NJ: Medical Economics.
    • (1993) Ciprofloxacin. 47Th , pp. 1636-1639
  • 156
    • 0023277409 scopus 로고
    • Induction of the SOS response in Escherichia coli by 4-quinolone antimicrobial agent
    • Piddock, L. J. V., and Wise, R. 1987. Induction of the SOS response in Escherichia coli by 4-quinolone antimicrobial agent. FEMS Microbiol. Lett. 41:289-294.
    • (1987) FEMS Microbiol. Lett , vol.41 , pp. 289-294
    • Piddock, L.J.V.1    Wise, R.2
  • 157
    • 0019722096 scopus 로고
    • Sex pheromone production by preputial gland: The regulatory role of estrogen
    • Pietras, R. J. 1981. Sex pheromone production by preputial gland: The regulatory role of estrogen. Chem. Senses. 6:391-408.
    • (1981) Chem. Senses , vol.6 , pp. 391-408
    • Pietras, R.J.1
  • 158
    • 0024350242 scopus 로고
    • Absence of cinoxacin-induced DNA fragmentation and muta-tions in the rat granuloma pouch
    • Pino, A., Maura, A., and Grillo, P. 1989. Absence of cinoxacin-induced DNA fragmentation and muta-tions in the rat granuloma pouch. Environ. Mol. Mutagen. 13:112-115.
    • (1989) Environ. Mol. Mutagen , vol.13 , pp. 112-115
    • Pino, A.1    Maura, A.2    Grillo, P.3
  • 159
    • 0025361784 scopus 로고
    • Injured mitochondria in cells of Euglena gracilis after DNA gyrase inhibitors treatment
    • Polonyi, J., Ebringer, L., Krajcovic, J., and Kapeller, K. 1990. Injured mitochondria in cells of Euglena gracilis after DNA gyrase inhibitors treatment. Z. Mikrosk.-Anat. Forsch. 104:61-78.
    • (1990) Z. Mikrosk.-Anat. Forsch , vol.104 , pp. 61-78
    • Polonyi, J.1    Ebringer, L.2    Krajcovic, J.3    Kapeller, K.4
  • 160
    • 85046519936 scopus 로고
    • Correlation between umuC induction and Salmonella mutagenicity assay for quinolone antimicrobial agents
    • Power, E. G., and Phillips, I. 1993. Correlation between umuC induction and Salmonella mutagenicity assay for quinolone antimicrobial agents. FEMS Microbiol. Lett. 112:251-254.
    • (1993) FEMS Microbiol. Lett , vol.112 , pp. 251-254
    • Power, E.G.1    Phillips, I.2
  • 162
    • 0016274995 scopus 로고
    • Photosensitivity from nalidixic acid. Br./
    • Ramsay, C. A., and Obreshfova, N. 1974. Photosensitivity from nalidixic acid. Br./. Dermatol. 91:523-528.
    • (1974) Dermatol , vol.91 , pp. 523-528
    • Ramsay, C.A.1    Obreshfova, N.2
  • 163
    • 0025277515 scopus 로고
    • Separate mechanisms for retinal damage by ultra- violet-A and mid-visible light
    • Rapp, L. M., Tolman, B. L., and Dhindsa, H. S. 1990. Separate mechanisms for retinal damage by ultra- violet-A and mid-visible light. Invest. Ophthalmol. Vis. Sci. 31:1186-1190.
    • (1990) Invest. Ophthalmol. Vis. Sci , vol.31 , pp. 1186-1190
    • Rapp, L.M.1    Tolman, B.L.2    Dhindsa, H.S.3
  • 164
    • 84916788310 scopus 로고
    • Does nalidixic acid produce joint toxicity in children?
    • Istanbul
    • Rumler, W., and Rohden, L. 1987. Does nalidixic acid produce joint toxicity in children? 15th Int. Congr. Chemotherapy, Proc. 1029-1031. Istanbul.
    • (1987) 15Th Int. Congr. Chemotherapy, Proc , pp. 1029-1031
    • Rumler, W.1    Rohden, L.2
  • 165
    • 0019975664 scopus 로고
    • The B. Subtilis multigene sporulation test for mutagens: Detection of mutagens inactive in the Salmonella his reversion test
    • Sacks, L. E., and MacGregor, J. T. 1982. The B. subtilis multigene sporulation test for mutagens: Detection of mutagens inactive in the Salmonella his reversion test. Mutat. Res. 95:191-202.
    • (1982) Mutat. Res , vol.95 , pp. 191-202
    • Sacks, L.E.1    Macgregor, J.T.2
  • 167
    • 13344251718 scopus 로고
    • Inhibitory effects of ofloxacin on DNA gyrase off. Coli and topoisomerase II of bovine calf thymus
    • Sato, K., Hoshino, K., Une, T., and Osada, Y. 1989. Inhibitory effects of ofloxacin on DNA gyrase off. coli and topoisomerase II of bovine calf thymus. Rev. Infect. Dis. 11:915-916.
    • (1989) Rev. Infect. Dis , vol.11 , pp. 915-916
    • Sato, K.1    Hoshino, K.2    Une, T.3    Osada, Y.4
  • 168
    • 0019216411 scopus 로고
    • Teratological study on cinoxacin in rabbits
    • Sato, T., and Kobayashi, F. 1980. Teratological study on cinoxacin in rabbits. Chemotherapy 28(S-4):508-515.
    • (1980) Chemotherapy , vol.28 , pp. 508-515
    • Sato, T.1    Kobayashi, F.2
  • 169
  • 170
    • 0026033898 scopus 로고
    • Phase IV study and post-marketing surveillance of ofloxacin in Japan
    • Sawada, M., Nakamura, S., Yamada, A., Kobayashi, T., and Okada, S. 1991. Phase IV study and post-marketing surveillance of ofloxacin in Japan. Chemotherapy 37:134-142.
    • (1991) Chemotherapy , vol.37 , pp. 134-142
    • Sawada, M.1    Nakamura, S.2    Yamada, A.3    Kobayashi, T.4    Okada, S.5
  • 172
    • 0026038559 scopus 로고
    • Clinical, radiologic and magnetic resonance monitoring for skeletal toxicity in pediatric patients with cystic fibrosis receiving a three-month course of ciprofloxacin
    • Schaad, U. B., Stoupis, C., Wedgwood, J., Tschaeppeler, H., and Vock, P. 1991. Clinical, radiologic and magnetic resonance monitoring for skeletal toxicity in pediatric patients with cystic fibrosis receiving a three-month course of ciprofloxacin. Pediatr. Infect. Dis. I. 10:723-729.
    • (1991) Pediatr. Infect. Dis. I , vol.10 , pp. 723-729
    • Schaad, U.B.1    Stoupis, C.2    Wedgwood, J.3    Tschaeppeler, H.4    Vock, P.5
  • 174
    • 0002816687 scopus 로고
    • Toxicology of ciprofloxacin
    • H. C. Neu and H. Weuta, Amsterdam: Excerpta Medica
    • Schluter, G. 1986. Toxicology of ciprofloxacin. In Proceedings of the First International Workshop, eds. H. C. Neu and H. Weuta, pp. 61-67. Amsterdam: Excerpta Medica.
    • (1986) Proceedings of the First International Workshop , pp. 61-67
    • Schluter, G.1
  • 175
    • 0026640720 scopus 로고
    • Effects of ofloxacin on chondrogenesis in murine cartilage organoid culture
    • Schroter-Kermani, C., Hinz, N., Risse, P., Stahlmann, R., and Merker, H.-J. 1992. Effects of ofloxacin on chondrogenesis in murine cartilage organoid culture. Toxicol. In Vitro 6:465-474.
    • (1992) Toxicol , vol.6 , pp. 465-474
    • Schroter-Kermani, C.1    Hinz, N.2    Risse, P.3    Stahlmann, R.4    Merker, H.-J.5
  • 179
    • 0025216809 scopus 로고
    • Safety profile of quinolones
    • Shah, P. M., and Mulert, R. 1990. Safety profile of quinolones. Eur. Urol. 17:46-51.
    • (1990) Eur. Urol , vol.17 , pp. 46-51
    • Shah, P.M.1    Mulert, R.2
  • 180
    • 0343142448 scopus 로고
    • Mutagenicity test battery for toxicity studies of drug: Status quo and prespective
    • Shimada, H. 1993. Mutagenicity test battery for toxicity studies of drug: Status quo and prespective. Environ. Mutat. Res. Commun. 15:109-121.
    • (1993) Environ. Mutat. Res. Commun , vol.15 , pp. 109-121
    • Shimada, H.1
  • 181
    • 84954939085 scopus 로고
    • Effect of DU-6859 and the related quinolone antibacterial agents on mammalian chromosomes
    • Chicago
    • Shimada, H., and Itoh, S. 1991. Effect of DU-6859 and the related quinolone antibacterial agents on mammalian chromosomes. 31st ICAAC abstr. 1507. Chicago.
    • (1991) 31St ICAAC Abstr. 1507
    • Shimada, H.1    Itoh, S.2
  • 182
    • 0019296231 scopus 로고
    • Lack of induction of dominant lethal mutations in male mice by nalidixic acid
    • Shimada, H., Morita, H., and Akimoto, T. 1980. Lack of induction of dominant lethal mutations in male mice by nalidixic acid. Toxicol. Lett. 7:165-170.
    • (1980) Toxicol. Lett , vol.7 , pp. 165-170
    • Shimada, H.1    Morita, H.2    Akimoto, T.3
  • 183
    • 0021227752 scopus 로고
    • Mutagenicity studies of DL-8280, a new antibacterial drug
    • Shimada, H., Ebine, Y., Kurosawa, Y., and Arauchi, T. 1984. Mutagenicity studies of DL-8280, a new antibacterial drug. Chemotherapy 32(S-1):1162-1170.
    • (1984) Chemotherapy , vol.32 , pp. 1162-1170
    • Shimada, H.1    Ebine, Y.2    Kurosawa, Y.3    Arauchi, T.4
  • 184
    • 0022258444 scopus 로고
    • Dominant lethal study in male mice treated with ofloxacin, a new antimicrobial drug
    • Shimada, H., Ebine, Y., Sato, T., Kurosawa, Y., and Arauchi, T. 1985. Dominant lethal study in male mice treated with ofloxacin, a new antimicrobial drug. Mutat. Res. 144:51-55.
    • (1985) Mutat. Res , vol.144 , pp. 51-55
    • Shimada, H.1    Ebine, Y.2    Sato, T.3    Kurosawa, Y.4    Arauchi, T.5
  • 186
    • 0027749699 scopus 로고
    • Phototoxic lesions induced by quinolone antibacterial agents in auricular skin and retina of albino mice
    • Shimoda, K., Yoshida, M., Wagai, N., Takayama, S., and Kato, M. 1993. Phototoxic lesions induced by quinolone antibacterial agents in auricular skin and retina of albino mice. Toxicol. Pathol. 21:554-561.
    • (1993) Toxicol. Pathol , vol.21 , pp. 554-561
    • Shimoda, K.1    Yoshida, M.2    Wagai, N.3    Takayama, S.4    Kato, M.5
  • 187
    • 0019181070 scopus 로고
    • Mutagenic activity test on cinoxacin in vitro and in vivo cytogenetic tests in mammalian cells
    • Shiratori, O., and Takase, S. 1980. Mutagenic activity test on cinoxacin in vitro and in vivo cytogenetic tests in mammalian cells. Chemotherapy 28(S-4):523-528.
    • (1980) Chemotherapy , vol.28 , pp. 523-528
    • Shiratori, O.1    Takase, S.2
  • 189
    • 0001414153 scopus 로고
    • Safety overview: Toxicity, adverse effects and drug interactions
    • V. Andriole, London: Academic Press
    • Stahlmann, R., and Lode, H. 1988. Safety overview: Toxicity, adverse effects and drug interactions. In The quinolones, ed. V. Andriole, pp. 201-233. London: Academic Press.
    • (1988) The Quinolones , pp. 201-233
    • Stahlmann, R.1    Lode, H.2
  • 190
    • 0025363780 scopus 로고
    • Ofloxacin in juvenile non-human primates and rats. Arthropathia and drug plasma concentrations
    • Stahlmann, R., Merker, H. J., Hinz, N., Chahoud, I., Webb, J., Heger, W., and Neubert, D. 1990. Ofloxacin in juvenile non-human primates and rats. Arthropathia and drug plasma concentrations. Arch. Toxicol. 64:193-204.
    • (1990) Arch. Toxicol , vol.64 , pp. 193-204
    • Stahlmann, R.1    Merker, H.J.2    Hinz, N.3    Chahoud, I.4    Webb, J.5    Heger, W.6    Neubert, D.7
  • 191
    • 0027332403 scopus 로고
    • Quinolone in children. Are concerns over arthropa-thy justified?
    • Stahlmann, R., Forster, C., and Van Sickle, D. 1993. Quinolone in children. Are concerns over arthropa-thy justified? Drug Safety 9:397-403.
    • (1993) Drug Safety , vol.9 , pp. 397-403
    • Stahlmann, R.1    Forster, C.2    Van Sickle, D.3
  • 192
    • 0014947701 scopus 로고
    • Effect of nalidixic acid on human chromosome integrity
    • Stenchever, M. A., Powell, W., and Jarvis, J. A. 1970. Effect of nalidixic acid on human chromosome integrity. Am.J. Obstet. Gynecol. 107:329-330.
    • (1970) Am.J. Obstet. Gynecol , vol.107 , pp. 329-330
    • Stenchever, M.A.1    Powell, W.2    Jarvis, J.A.3
  • 193
    • 0025678788 scopus 로고
    • Fertility study of fleroxacin in rats
    • Suzuki, H., Takahashi, T., Sato, Y., and Abe, Y. 1990a. Fertility study of fleroxacin in rats. Chemotherapy 38(S-21):261-271.
    • (1990) Chemotherapy , vol.38 , pp. 261-271
    • Suzuki, H.1    Takahashi, T.2    Sato, Y.3    Abe, Y.4
  • 195
    • 0026541079 scopus 로고
    • Effects of the combination of new quinolones and an anti-inflammatory drug, fenbufen, on the EEC of rabbits
    • Suzuki, T., Hara, Y., Tamagawa, M., Kakizawa, K., and Murayama, S. 1992. Effects of the combination of new quinolones and an anti-inflammatory drug, fenbufen, on the EEC of rabbits. Folia Pharmacol. Ipn. 99:45-54.
    • (1992) Folia Pharmacol. Ipn , vol.99 , pp. 45-54
    • Suzuki, T.1    Hara, Y.2    Tamagawa, M.3    Kakizawa, K.4    Murayama, S.5
  • 197
    • 0028260786 scopus 로고
    • Comparison of lesions induced by intra-articular injections of quinolones and compounds damaging cartilage components in rat femoral condyles
    • Takada, S., Kato, M., and Takayama, S. 1994. Comparison of lesions induced by intra-articular injections of quinolones and compounds damaging cartilage components in rat femoral condyles. J. Toxicol. Environ. Health 42:73-88.
    • (1994) J. Toxicol. Environ. Health , vol.42 , pp. 73-88
    • Takada, S.1    Kato, M.2    Takayama, S.3
  • 200
    • 0025037268 scopus 로고
    • Pharmacological study on CNS action of new quinolone with special reference to drug interaction with NSAID
    • Takeda, N. 1990. Pharmacological study on CNS action of new quinolone with special reference to drug interaction with NSAID. Acta Sch. Med. Univ. Gifu 38:742-756.
    • (1990) Acta Sch. Med. Univ. Gifu , vol.38 , pp. 742-756
    • Takeda, N.1
  • 202
  • 203
    • 0018250533 scopus 로고
    • Toxicological studies on pipemidic acid. V. Effect on diarthrodial joints of experimental animals
    • Tatsumi, H., Senda, H., Yatera, S., Takemoto, Y., Yamayoshi, M., and Ohnishi, K. 1978. Toxicological studies on pipemidic acid. V. Effect on diarthrodial joints of experimental animals. J. Toxicol. Sci. 3:357-367.
    • (1978) J. Toxicol. Sci , vol.3 , pp. 357-367
    • Tatsumi, H.1    Senda, H.2    Yatera, S.3    Takemoto, Y.4    Yamayoshi, M.5    Ohnishi, K.6
  • 205
    • 0021327770 scopus 로고
    • Reproduction studies of AT-2266. (2) Effects on male fertility in rats (serial mating study)
    • Terada, Y., Nishimura, K., Takenaka, H., and Yoshida, K. 1984b. Reproduction studies of AT-2266. (2) Effects on male fertility in rats (serial mating study). Chemotherapy 32(S-3):293-300.
    • (1984) Chemotherapy , vol.32 , pp. 293-300
    • Terada, Y.1    Nishimura, K.2    Takenaka, H.3    Yoshida, K.4
  • 207
    • 84954952503 scopus 로고
    • Reproductive and develop-mental toxicity studies of sparfloxacin. (4) Teratogenicity study in rabbits
    • Terada, Y., Mukumoto, K., Imura, Y., Nishimura, K., and Ohnishi, K. 1991. Reproductive and develop-mental toxicity studies of sparfloxacin. (4) Teratogenicity study in rabbits. Yakuri to Chiryou 19:1289-1297.
    • (1991) Yakuri to Chiryou , vol.19 , pp. 1289-1297
    • Terada, Y.1    Mukumoto, K.2    Imura, Y.3    Nishimura, K.4    Ohnishi, K.5
  • 208
    • 0018609475 scopus 로고
    • Dominant lethal mutation test of miloxacin
    • Tokunaga, Y., Asaba, M., and Kato, R. 1979. Dominant lethal mutation test of miloxacin. Ohyo Yakuri. 18:37-45.
    • (1979) Ohyo Yakuri , vol.18 , pp. 37-45
    • Tokunaga, Y.1    Asaba, M.2    Kato, R.3
  • 209
    • 0021691394 scopus 로고
    • Modifying potential of thirty-one chemicals on the short-term development of y-glutamyl transferase-positive in diethylni- trosamine-initiated rat liver
    • Tsuda, H., Hasegawa, R., Imaida, K., Masui, T., Malcolm, A., and Ito, N. 1984. Modifying potential of thirty-one chemicals on the short-term development of y-glutamyl transferase-positive in diethylni- trosamine-initiated rat liver. Gann 75:876-883.
    • (1984) Gann , vol.75 , pp. 876-883
    • Tsuda, H.1    Hasegawa, R.2    Imaida, K.3    Masui, T.4    Malcolm, A.5    Ito, N.6
  • 210
    • 0023697650 scopus 로고
    • Effect of the anti-inflammatory agent fenbufen on the quinolone-induced inhibition of y-aminobutyric acid binding to rat brain mem-brane in vitro
    • Tsuji, A., Sato, H., Okezaki, E., Nagata, O., and Kato, H. 1988. Effect of the anti-inflammatory agent fenbufen on the quinolone-induced inhibition of y-aminobutyric acid binding to rat brain mem-brane in vitro. Biochem. Pharmacol. 37:4408-4411.
    • (1988) Biochem. Pharmacol , vol.37 , pp. 4408-4411
    • Tsuji, A.1    Sato, H.2    Okezaki, E.3    Nagata, O.4    Kato, H.5
  • 211
    • 0020201119 scopus 로고
    • A bioluminescence test for genotoxic agents
    • Ulitzur, S. 1982. A bioluminescence test for genotoxic agents. Trends Anal. Chem. 1:329-333.
    • (1982) Trends Anal. Chem , vol.1 , pp. 329-333
    • Ulitzur, S.1
  • 212
    • 85004377824 scopus 로고
    • Teratological study of oral administration of NY-198 in rabbits
    • Umemura, T., Sasa, H., lizuka, T., and Yanagita, T. 1988. Teratological study of oral administration of NY-198 in rabbits. Chemotherapy 36(S-2):391-410.
    • (1988) Chemotherapy , vol.36 , pp. 391-410
    • Umemura, T.1    Sasa, H.2    Lizuka, T.3    Yanagita, T.4
  • 213
    • 49549156600 scopus 로고
    • Mutagenic effect of nalidixic acid on bacteriophage T4. Mutat
    • Vigier, P. R. R. 1974. Mutagenic effect of nalidixic acid on bacteriophage T4. Mutat. Res. 25:25-32.
    • (1974) Res , vol.25 , pp. 25-32
    • Vigier, P.R.R.1
  • 214
    • 0025773284 scopus 로고
    • Important role of oxygen metabolites in quinolone antibacterial agent- induced cutaneous phototoxicity in mice
    • Wagai, N., and Tawara, K. 1991a. Important role of oxygen metabolites in quinolone antibacterial agent- induced cutaneous phototoxicity in mice. Arch. Toxicol. 65:495-499.
    • (1991) Arch. Toxicol , vol.65 , pp. 495-499
    • Wagai, N.1    Tawara, K.2
  • 215
    • 0025788691 scopus 로고
    • Quinolone antibacterial-agent-induced cutaneous phototoxicity: Ear swelling reactions in BALB/c mice
    • Wagai, N. J and Tawara, K. 1991b. Quinolone antibacterial-agent-induced cutaneous phototoxicity: Ear swelling reactions in BALB/c mice. Toxicol. Lett. 58:215-223.
    • (1991) Toxicol. Lett , vol.58 , pp. 215-223
    • Wagai, N.J.1    Tawara, K.2
  • 216
    • 0026627750 scopus 로고
    • Possible direct role of reactive oxygens in the cause of cutaneous pho-totoxicity induced by five quinolones in mice
    • Wagai, N., and Tawara, K. 1992. Possible direct role of reactive oxygens in the cause of cutaneous pho-totoxicity induced by five quinolones in mice. Arch. Toxicol. 66:392-397.
    • (1992) Arch. Toxicol , vol.66 , pp. 392-397
    • Wagai, N.1    Tawara, K.2
  • 217
    • 0024467953 scopus 로고
    • Studies on experimental conditions for detecting phototoxic potentials in BALB/c mice
    • Wagai, N., Yamaguchi, F., Tawara, K., and Onodera, T. 1989. Studies on experimental conditions for detecting phototoxic potentials in BALB/c mice. I. Toxicol. Sci. 14:197-204.
    • (1989) I. Toxicol. Sci , vol.14 , pp. 197-204
    • Wagai, N.1    Yamaguchi, F.2    Tawara, K.3    Onodera, T.4
  • 218
    • 0025674211 scopus 로고
    • Phototoxic potential of quinolone antibacterial agents in BALB/c mice
    • Wagai, N., Yamaguchi, F., Sekiguchi, M., and Tawara, K. 1990. Phototoxic potential of quinolone antibacterial agents in BALB/c mice. Toxicol. Lett. 54:299-308.
    • (1990) Toxicol. Lett , vol.54 , pp. 299-308
    • Wagai, N.1    Yamaguchi, F.2    Sekiguchi, M.3    Tawara, K.4
  • 219
    • 0023693001 scopus 로고
    • Mutagenicity studies on NY-198 in bacteria
    • Wakisaki, H., Koike, S., and Makino, E. 1988. Mutagenicity studies on NY-198 in bacteria. Chemotherapy 36(S-2):422-427.
    • (1988) Chemotherapy , vol.36 , pp. 422-427
    • Wakisaki, H.1    Koike, S.2    Makino, E.3
  • 220
    • 0026832581 scopus 로고
    • Reproductive toxicity of the new quinolone antibacterial agent levofloxacin in rats and rabbits
    • Watanabe, T., Fujikawa, K., Harada, S., Ohura, K., Sasaki, T., and Takayama, S. 1992. Reproductive toxicity of the new quinolone antibacterial agent levofloxacin in rats and rabbits. Arzneim.- ForschJDrug Res. 42:374-377.
    • (1992) Arzneim.- Forschjdrug Res , vol.42 , pp. 374-377
    • Watanabe, T.1    Fujikawa, K.2    Harada, S.3    Ohura, K.4    Sasaki, T.5    Takayama, S.6
  • 221
    • 0025826190 scopus 로고
    • The proconvulsive activity of quinolone antibiotics in an animal model
    • Williams, P. D., and Helton, D. R. 1991. The proconvulsive activity of quinolone antibiotics in an animal model. Toxicol. Lett. 58:23-28.
    • (1991) Toxicol. Lett , vol.58 , pp. 23-28
    • Williams, P.D.1    Helton, D.R.2
  • 222
    • 0021330466 scopus 로고
    • Validation of the Salmonella (SV50)/arabinose-resistant forward mutation assay system with 26 compounds
    • Xu, J., Whong, W.-Z., and Ong, T.-M. 1984. Validation of the Salmonella (SV50)/arabinose-resistant forward mutation assay system with 26 compounds. Mutat. Res. 130:79-86.
    • (1984) Mutat. Res , vol.130 , pp. 79-86
    • Xu, J.1    Whong, W.-Z.2    Ong, T.-M.3
  • 223
    • 0019293635 scopus 로고
    • General pharmacology of cinoxacin. 1. Effects on the central nervous system
    • Yamamoto, K., Yoshimura, K., and Matsushita, A. 1980. General pharmacology of cinoxacin. 1. Effects on the central nervous system. Chemotherapy 28(S-4):530-549.
    • (1980) Chemotherapy , vol.28 , pp. 530-549
    • Yamamoto, K.1    Yoshimura, K.2    Matsushita, A.3
  • 224
    • 85004443735 scopus 로고
    • Seizure discharges induced by the com-bination of a new quinolinecarboxylic acid antimicrobial drugs and non-steroidal anti-inflammatory drugs-Effect of NY-198 on the central nervous system
    • Yamamoto, K., Naitoh, Y., Inoue, Y., and Yoshimura, K. 1988. Seizure discharges induced by the com-bination of a new quinolinecarboxylic acid antimicrobial drugs and non-steroidal anti-inflammatory drugs-Effect of NY-198 on the central nervous system. Chemotherapy 36(S-2):300-324.
    • (1988) Chemotherapy , vol.36 , pp. 300-324
    • Yamamoto, K.1    Naitoh, Y.2    Inoue, Y.3    Yoshimura, K.4
  • 225
    • 0018948748 scopus 로고
    • Deoxyribonucleic acid repair in Bacillus subtilis: Development of competent cells into a tester for carcinogens
    • Yasbin, R. E., and Miehl, R. 1980. Deoxyribonucleic acid repair in Bacillus subtilis: Development of competent cells into a tester for carcinogens. Appl. Environ. Microbiol. 39:854-858.
    • (1980) Appl. Environ. Microbiol , vol.39 , pp. 854-858
    • Yasbin, R.E.1    Miehl, R.2
  • 226
    • 9344261067 scopus 로고
    • Photosensitive drug eruption due to lomefloxacin
    • Yoshizawa, M., Hashimoto, A., and Asai, T. 1992. Photosensitive drug eruption due to lomefloxacin. Rinsho-Hifu 46:463-466.
    • (1992) Rinsho-Hifu , vol.46 , pp. 463-466
    • Yoshizawa, M.1    Hashimoto, A.2    Asai, T.3
  • 227
    • 84936226793 scopus 로고
    • Clinical experience with the newer quinolones. Res
    • Young, L. S. 1985. Clinical experience with the newer quinolones. Res. Clin. Forms 7:97-114.
    • (1985) Clin. Forms , vol.7 , pp. 97-114
    • Young, L.S.1
  • 228
    • 84954967807 scopus 로고
    • Preface
    • S. Alder and G. Zbinden, Zollikon, Switzerland: M.T.C. Verlag Zollikon
    • Zbinden, G. 1988. Preface. In National and international drug safety guidelines, eds. S. Alder and G. Zbinden, pp. 5-6. Zollikon, Switzerland: M.T.C. Verlag Zollikon.
    • (1988) National and International Drug Safety Guidelines , pp. 5-6
    • Zbinden, G.1
  • 229
    • 0024518858 scopus 로고
    • Clinical overview of enoxacin
    • Zinner, S. H. 1989. Clinical overview of enoxacin. Clin. Pharmacokinet. 16(S-11):59-64.
    • (1989) Clin. Pharmacokinet , vol.16 , pp. 59-64
    • Zinner, S.H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.