Heparin‐induced thrombocytopenia: an improved method of detection based on lumi‐aggregometry

British Journal of Haematology

Volumn 91, Issue 1, 1995, Pages 173-177

  Stewart, Michael W ^a   Etches, Wai S ^a   Boshkov, Lynn K ^a   Gordon, Philip A ^a  

^a UNIVERSITY OF ALBERTA HOSPITAL   (Canada)

Author keywords

aggregometry; heparin; luminography; platelet; thrombocytopenia

Indexed keywords

HEPARIN;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; QUANTITATIVE ASSAY; THROMBOCYTE AGGREGATION; THROMBOCYTOPENIA;

ADENOSINE TRIPHOSPHATE; ANTICOAGULANTS; HEPARIN; HUMAN; LUMINESCENCE; PLATELET ACTIVATION; PLATELET FUNCTION TESTS; SEROTONIN; THROMBOCYTOPENIA;

EID: 0029027906     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.1995.tb05265.x     Document Type: Article

References (19)

1. Platelet factor 4 coraplexed to heparin is the target for antibodies generated in heparin‐induced thrombocytopenia
2. Heparin‐induced thrombocytopenia: effect of heparin platelet antibody on platelets
3. Increased expression of platelet IgG Fc receptors in immune heparin‐induced thrombocytopenia
4. The platelet aggregating effect of eight commercial heparins
5. A rapid and sensitive test for diagnosing heparin‐associated thrombocytopenia
6. Heparin‐associated thromobcytopenia: Isolation of the antibody and characterization of a multimolecular PF‐4 heparin complex as the major antigen
7. Specific quantification of heparin‐dependent antibodies for the diagnosis of heparin‐associated thrombocytopenia using an enzyme‐linked immunosorbent assay
8. Heparin binding to normal and abnormal platelets
9. The effect of secreted heparin‐binding proteins on heparin binding to platelets
10. Investigation of the mechanisms of monoclonal antibody‐induced platelet activation
11. A quick method for screening platelet dysfunctions using the whole blood lumi‐aggregometer
12. Heparin induced thrombocytopenia: a prospective study of 142 patients
13. Heparin‐induced thrombocytopenia: laboratory studies
14. Immunoglobulin G from patients with heparin‐induced thrombocytopenia binds to a complex of heparin and platelet factor 4
15. Treatment of heparin‐associated thrombocytopenia and thrombosis with low molecular weight heparin (CY216)
16. A diagnostic test for heparin‐induced thrombocytopenia
17. vWf bead‐induced platelet activation: detection of a platelet function defect in a patient population with mild bleeding and/or easy‐bruising. (Abstract). Thrombosis
18. Antibodies from patients with heparin‐induced thrombocytopenia/thrombosis are specific for platelet factor 4 complexed with heparin or bound to endothelial cells
19. Effect of heparin on platelet function