Allelotyping of follicular thyroid tumors

Human Genetics

Volumn 96, Issue 1, 1995, Pages 27-32

  Zedenius, Jan ^a   Wallin, Göran ^a   Svensson, Ann ^a   Grimelius, Lars ^b   Höög, Anders ^a   Lundell, Göran ^a   Bäckdahl, Martin ^a   Larsson, Catharina ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b UPPSALA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOMA; ALLELE; ARTICLE; CHROMOSOME 10Q; CHROMOSOME 11Q; CHROMOSOME 13Q; CHROMOSOME 18Q; CHROMOSOME 22Q; CHROMOSOME 3Q; GENOTYPE; HETEROZYGOSITY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; THYROID PARAFOLLICULAR CELL; THYROID TUMOR; TUMOR GROWTH;

ADENOCARCINOMA, FOLLICULAR; ALLELES; CHROMOSOME DELETION; CHROMOSOMES, HUMAN; DNA, NEOPLASM; DNA, SATELLITE; GENES, TUMOR SUPPRESSOR; HETEROZYGOTE; HUMAN; POLYMERASE CHAIN REACTION; POLYMORPHISM (GENETICS); REPETITIVE SEQUENCES, NUCLEIC ACID; SUPPORT, NON-U.S. GOV'T; THYROID NEOPLASMS;

EID: 0029024750     PISSN: 03406717     EISSN: 14321203     Source Type: Journal    
DOI: 10.1007/BF00214182     Document Type: Article

References (35)

1. Cytogenetic abnormalities in thyroid adenomas
2. Numerical aberrations, including trisomy 22 as the sole anomaly, are recurrent in follicular thyroid adenomas
3. Cytogenetic findings on eight follicular adenomas including one with a t(10;19)
4. Deletion of part of the long arm of chromosome 13 as the only karyotypic aberration in a follicular thyroid adenoma
5. Aberrations of chromosome 19. Do they characterize a subtype of benign thyroid adenomas?
6. A characteristic sequence of trisomies starting with trisomy 7 in benign thyroid tumors
7. Deletion mapping in renal cell carcinoma
8. Loss of the retinoblastoma tumor-suppressor gene in parathyroid carcinoma
9. Gene p53 mutations are restricted to poorly differentiated and undifferentiated carcinomas of the thyroid gland
10. Molecular defects in thyroid gland neoplasia
11. High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas
12. Molecular basis of thyroid cancer
13. Mutational activation of RAS and GSP oncogenes in differentiated thyroid cancer and their biological implications
14. Cytogenetic and molecular genetic studies of follicular and papillary thyroid cancers
15. Clonal analysis of solitary follicular nodules in the thyroid
16. Unique association of p53 mutations with undifferentiated but not with differentiated carcinomas of the thyroid gland
17. Frequent occurrence of cytogenetic abnormalities in sporadic nonmedullary thyroid carcinoma
18. Loss of heterozygosity on chromosome 1p in thyroid adenoma and medullary carcinoma, but not in papillary carcinoma
19. Genomic alterations in human breast carcinomas
20. High frequency of ras oncogene activation in all stages of human thyroid tumorigenesis
21. Allelotype of human thyroid tumors: loss of chromosome 11q13 sequences in follicular neoplasms
22. Point mutations of ras oncogenes are an early event in thyroid tumorigenesis
23. Clonal composition of benign and malignant human thyroid tumors
24. Activating point mutations of the gsp oncogene in human thyroid adenomas
25. Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas
26. Translocation t(5; 19): a recurrent change in thyroid follicular adenoma
27. Deletion of 3p25 →pter in a primary follicular thyroid carcinoma and its metastasis
28. Ring 10 chromosome: 46, XX, r10(p15q26)
29. Presence of mutations in all three ras genes in human thyroid tumors
30. gsp mutations in human thyroid tumours
31. Numerical chromosomal aberrations in thyroid tumors detected by double fluorescence in situ hybridization
32. Constitutional ring chromosomes and tumour suppressor genes
33. Molecular basis of epithelial tumorigenesis: the thyroid model
34. Follicular tumors of the thyroid gland; diagnosis, clinical aspects and nuclear DNA content