Increased incidence of neurofibrillary tangles (NFT) in non-demented individuals with hypertension

Journal of the Neurological Sciences

Volumn 131, Issue 2, 1995, Pages 162-169

  Sparks, D Larry ^a,b   Scheff, Stephen W ^a,b   Liu, Huaichen ^a,b   Landers, Teresa M ^a,b   Coyne, Carolyn M ^a,b   Hunsaker III, John C ^a,b  

^a UNIVERSITY OF KENTUCKY MEDICAL CENTER   (United States)

^b C 439 Transplant CenterUniversity   (United States)

Author keywords

Alzheimer's disease; Coronary artery disease; Hypertension; Neurofibrillary tangles; Non heart disease controls; Senile plaques

Indexed keywords

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; NEUROFIBRILLARY TANGLE; PRIORITY JOURNAL; SENILE PLAQUE;

AGE FACTORS; AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; ANTIBODIES, MONOCLONAL; BIOLOGICAL MARKERS; COMPARATIVE STUDY; CORONARY DISEASE; DEMENTIA; HUMAN; HYPERTENSION; IMMUNOHISTOCHEMISTRY; INCIDENCE; MIDDLE AGE; NEUROFIBRILLARY TANGLES;

EID: 0029020269     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0022-510X(95)00105-B     Document Type: Article

References (62)

1. Women, myocardial infarction, and dementia in the very old
2. Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease
3. The association between quantitative measures of dementia and of senile changes in cerebral grey matter of elderly subjects
4. Regional distribution of neurofibrillary tangles and senile plaques in the cerebral cortex of elderly patients: a quantitative evaluation of a one-year autopsy population from a geriatric hosptial
5. Neurofibrillary tangle densities in the hippocampal formation in a non-demented population define subgroups of patients with differential early pathologic changes
6. Apolipoprotein E phenotyping with a single gel method: Application to the study of informative matings
7. Neurofibrillary changes confined to the entorhinal region and an abundance of cortical amyloid in cases of presenile and senile dementia
8. Neuropathological stageing of Alzheimer-related changes
9. Cardiovascular disease and distribution of cognitive function in elderly people: The Rotterdam study
10. Relationship between the extent of coronary artery disease and indicators of free radical activity
11. Relationship of ischemic heart disease to sudden death
12. Clinicopathologic studies in dementia. Nondemented subjects with pathologically confirmed Alzheimer's disease
13. Cardiac status in juvenile borderline hypertension
14. Factors involved in pathogenesis of hypertesive cardiovascular hypertrophy
15. Drugs for hypertension
16. Laminar distribution of neocortical senile plaques in senile dementia of the Alzheimer type
17. Quantitative assessment of the density of neurofibrillary tangles and senile plaques in senile dementia of the Alzheimer type. Comparison of immunocytochemistry with a specific antibody and Bodian's protargol method
18. Does amyloid precede paired helical filaments in the senile plaque? A study of 15 cases with graded intellectual status in aging and Alzheimer disease
19. Potential mechanisms explaining the risk of left ventricular hypertrophy
20. Prelesional events in atherogenesis. Changes induced by hypercholesterolemia in the cell surface chemistry of arterial endothelium and blood monocytes, in rabbit
21. Hydroflouric acid-treated tau PHF proteins display the same biochemical proterties as normal tau
22. Evidence for early vulnerability of the medial and inferior apsects of the temporal lobe in an 82-year old patient with preclinical signs of dementia
23. Age-related distribution of neuropathologic changes in the cerebral cortex of Down Syndrome cases: Quantitative regional analysis and comparison with Alzheimer's disease
24. Inter-Society commission for heart disease resourses Optimal resourses for primary prevention of atherosclerotic disease
25. Lipid peroxidation and free radical scavengers in Alzheimer's disease
26. Subcommittee of definition and prevalence of the 1984 joint National Committee: Hypertension prevalence and the status of awareness, treatment, and control in the United States
27. Clinical, pathological and neurochemical changes in dementia: a subgroup with preserved mental status and numerous neocortical plaques
28. Clinicopathologic correlates in Alzheimer's disease: Assessment of clinical and pathologic diagnostic criteria
29. Diagnosis of Alzheimer's disease
30. Serum cholesterol in young men and subsequent cardiovascular disease
31. Sudden death and cardiomegaly unassociated with coronary, valvular, congenital or specific myocardial disease
32. Echocardiographically detected left ventricular hypertrophy: Prevalence and risk factors. The Framingham heart study
33. Oxidative status of lipoproteins in coronary disease patients
34. Clinical determinants and consequences of left ventricular hypertrophy
35. The consortium to establish a registry for Alzheimer's disease (CERAD) II. Standardization of the neuropathologic assessment of Alzheimer's disease
36. Very mild Alzheimer's disease: informant-based clinical, psychometric, and pathologic distinction from normal aging
37. Phosphorylated tau epitope of Alzheimer's disease is coupled to axon development in the avian central nervous system
38. The distribution of tangles, plaques and related immunohistochemical markers in health, aging and Alzheimer's disease
39. Risk factors for Alzheimer's disease and dementia a case-control study based on the MRC elderly hypertension trial
40. The coronary arteries in ischemic heart disease: facts and fancies
41. Apolipoprotein E affects the rate of Alzheimer disease expression: β-amyloid burden is a secondary consequence dependent on APO-E genotype and duration of disease
42. Changes in rat hippocampal benzodiazepine receptors and lack of changes in muscarinic receptors after fimbria-fornix lesions
43. Immunolocalization of native antioxidant scavenger enzymes in early hypertensive and atherosclerotic arteries
44. Role of apolipoprotein E polymorphism in determining normal plasma lipid and lipoprotein variation
45. Down's Syndrome: Occurrence of ALZ-50 reactive neurons and the formation of senile plaques
46. Cortical senile plaques in coronary artery disease, aging and Alzheimer's disease
47. Neurochemical and histopathologic alterations characteristic of Pick's disease in a non-demented individual
48. Temporal sequence of plaque formation in the cerebral cortex of non-demented individuals
49. Autopsy samples of Alzheimer's cortex show increased peroxidation in vitro
50. Quantitative measures of the severity of hypertensive nephrosclerosis
51. Nephrosclerosis and blood pressure. I. Rising and falling patterns in lengthly records
52. Nephrosclerosis and blood pressure. II. Reversibility of proliferative arteriosclerosis
53. Alzheimer changes in nondemented patients younger than sixty-five: Possible early stages of Alzheimer's disease and senile dementia of Alzheimer type
54. Senile plaques: Staining for acetylcholinesterase and A4 protein: a comparative study in the hippocampus and entorhinal cortex
55. Apolipoprotein E phenotypes and hyperlipidemia
56. Progressive transformation of the cytoskeleton associated with normal aging and Alzheimer's disease
57. Examination of the heart
58. Involvement of free radicals in dementia of the Alzheimer type: a hypothesis
59. Intelligence and blood pressure in the aged
60. Probability of stroke: a risk profile for the Framingham study
61. Evidence for the presence of oxidately modified low density lipoprotein in atherosclerotic lesions of rabbit and man