The effect of water content on the porosity and liquid saturation of extruded cylinders

International Journal of Pharmaceutics

Volumn 121, Issue 1, 1995, Pages 65-71

  Jerwanska, E ^a   Alderborn, G ^a   Newton, J M ^b   Nystrom C ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Dicalcium phosphate dihydrate; Extruded cylinder; Extrusion; Liquid saturation; Microcrystalline cellulose; Porosity; Ram extruder; Water content

Indexed keywords

CALCIUM PHOSPHATE DIBASIC; CELLULOSE; MICROCRYSTALLINE CELLULOSE;

ARTICLE; DISPERSION; KINETICS; MOISTURE; PARTICLE SIZE; PLASTICITY; POWDER; PRIORITY JOURNAL; TABLET MANUFACTURE;

EID: 0029019149     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-5173(95)00007-6     Document Type: Article

References (12)

1. Studies on direct compression of tablets
2. Evaluation of heat-conduction microcalorimetry in pharmaceutical stability studies: IV. The influence of microcrystalline cellulose on the hydration rate of anhydrous lactose
3. A simplified air permeability fineness apparatus
4. The extrusion mechanics of pastes-the influence of paste formulation on extrusion parameters
5. Flow defects in wet powder mass extrusion
6. The characterisation of wet powder masses suitable for extrusion/spheronization
7. Studies on direct compression of of tablets: XXI. Investigation of bonding mechanisms of some directly compressed materials by strength characterisation in media with different dielectric constants (relative permittivity)
8. The effect of moisture on the density, compaction and tensile strength of microcrystalline cellulose
9. Mechanical properties of moist agglomerates in relation to granulation mechanisms: I Deformability of moist, densified agglomerates
10. Mechanical properties of moist agglomerates in relation to granulation mechanisms: II. Effects of particle size distribution
11. Effects of die geometry on the extrusion of clay-like material
12. Spheronization: a novel pill-making process?