Identification of a new family of tissue-specific basic helix-loop-helix proteins with a two-hybrid system

Molecular and Cellular Biology

Volumn 15, Issue 7, 1995, Pages 3813-3822

  Hollenberg, Stanley M ^a,c   Sternglanz, Rolf ^b   Cheng, Pei Feng ^a   Weintraub, Harold ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b STONY BROOK UNIVERSITY   (United States)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HELIX LOOP HELIX PROTEIN; HYBRID PROTEIN; TRANSCRIPTION FACTOR;

ARTICLE; BINDING AFFINITY; DNA TRANSFECTION; DROSOPHILA; GENE REPRESSION; IN SITU HYBRIDIZATION; NEURAL CREST; PRIORITY JOURNAL; PROTEIN ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE SPECIFICITY;

EID: 0029018708     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.15.7.3813     Document Type: Article

References (69)

1. Altschul, S. F., W. Gish, W. Miller, E. W. Myers, and D. J. Lipman. 1990. Basic local alignment search tool. J. Mol. Biol. 215:403-410.
2. Baer, R. 1993. TAL1, TAL2, and LYL1: a family of basic helix-loop-helix proteins implicated in T cell acute leukaemia. Semin. Cancer Biol. 4:341-347.
3. Bartel, P., C. T. Chien, R. Sternglanz, and S. Fields. 1993. Elimination of false positives that arise in using the two-hybrid system. BioTechniques 14:920-924.
4. Bartel, P. L., C. Chien, R. Sternglanz, and S. Fields. 1993. Using the two-hybrid system to detect protein-protein interactions, p. 153-179. In D. A. Hartley (ed.), Cellular interactions in development: a practical approach. IRL Press, Oxford.
5. Begley, C. G., J. Visvader, A. R. Green, P. D. Aplan, D. Metcalf, I. R. Kirsch, and N. M. Gough. 1991. Molecular cloning and chromosomal localization of the murine homolog of the human helix-loop-helix gene SCL. Proc. Natl. Acad. Sci. USA 88:869-873.
6. Benezra, R., R. L. Davis, D. Lockshon, D. L. Turner, and H. Weintraub. 1990. The protein Id: a negative regulator of helix-loop-helix DNA binding proteins. Cell 61:49-59.
7. Blackwell, T. K., J. Huang, A. Ma, L. Kretzner, F. W. Alt, R. N. Eisenman, and H. Weintraub. 1993. Binding of Myc proteins to canonical and noncanonical DNA sequences. Mol. Cell. Biol. 13:5216-5224.
8. Blackwell, T. K., and H. Weintraub. 1990. Differences and similarities in DNA-binding preferences of MyoD and E2A protein complexes revealed by binding site selection. Science 250:1104-1110.
9. Braun, T., B. Winter, E. Bober, and H. H. Arnold. 1990. Transcriptional activation domain of the muscle-specific gene-regulatory protein myf5. Nature (London) 346:663-665.
10. Brown, L., and R. Baer. 1994. HEN1 encodes a 20-kilodalton phosphoprotein that binds an extended E-box motif as a homodimer. Mol. Cell. Biol. 14:1245-1255.
11. Brown, L., R. Espinosa, M. M. Le Beau, M. Siciliano, and R. J. Baer. 1992. HEN1 and HEN2: a subgroup of basic helix-loop-helix genes that are coexpressed in a human neuroblastoma. Proc. Natl. Acad. Sci. USA 89:8492-8496.
12. Campos-Ortega, J. A. 1993. Mechanisms of early neurogenesis in Drosophila melanogaster. J. Neurobiol. 24:1305-1327.
13. Campuzano, S., and J. Modolell. 1992. Patterning of the Drosophila nervous system: the achaete-scute gene complex. Trends Genet. 8:202-208.
14. Chen, Q., J. T. Cheng, L. H. Tsai, N. Schneider, G. Buchanan, A. Carroll, W. Crist, B. Ozanne, M. J. Siciliano, and R. Baer. 1990. The tal gene undergoes chromosome translocation in T cell leukemia and potentially encodes a helix-loop-helix protein. EMBO J. 9:415-424.
15. Chien, C. T., P. L. Bartel, R. Sternglanz, and S. Fields. 1991. The two-hybrid system: a method to identify and clone genes for proteins that interact with a protein of interest. Proc. Natl. Acad. Sci. USA 88:9578-9582.
16. Christy, B. A., L. K. Sanders, L. F. Lau, N. G. Copeland, N. A. Jenkins, and D. Nathans. 1991. An Id-related helix-loop-helix protein encoded by a growth factor-inducible gene. Proc. Natl. Acad. Sci. USA 88:1815-1819.
17. Cowell, I. G. 1994. Repression versus activation in the control of gene transcription. Trends Biochem. Sci. 19:38-42.
18. Dang, C. V., C. Dolde, M. L. Gillison, and G. J. Kato. 1992. Discrimination between related DNA sites by a single amino acid residue of Myc-related basic-helix-loop-helix proteins. Proc. Natl. Acad. Sci. USA 89:599-602.
19. Edmondson, D. G., and E. N. Olson. 1990. A gene with homology to the myc similarity region of MyoD1 is expressed during myogenesis and is sufficient to activate the muscle differentiation program. Genes Dev. 3:628-640.
20. Ellenberger, T., D. Fass, M. Arnaud, and S. C. Harrison. 1994. Crystal structure of transcription factor E47: E-box recognition by a basic region helix-loop-helix dimer. Genes Dev. 8:970-980.
21. Ferré-D'Amaré, A. R., G. C. Prendergast, E. B. Ziff, and S. K. Burley. 1993. Recognition by Max of its cognate DNA through a dimeric b/HLH/Z domain. Nature (London) 363:38-45.
22. Fields, S., and O. Song. 1989. A novel genetic system to detect protein-protein interactions. Nature (London) 340:245-246.
23. Fields, S., and R. Sternglanz. 1994. The two-hybrid system: an assay for protein-protein interactions. Trends Genet. 10:286-292.
24. Frohman, M. A., M. K. Dush, and G. R. Martin. 1988. Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer. Proc. Natl. Acad. Sci. USA 85:8998-9002.
25. Gobel, V., S. Lipkowitz, C. A. Kozak, and I. R. Kirsch. 1992. NSCL-2: a basic domain helix-loop-helix gene expressed in early neurogenesis. Cell Growth Differ. 3:143-148.
26. Golemis, E. A., and R. Brent. 1992. Fused protein domains inhibit DNA binding by LexA. Mol. Cell. Biol. 12:3006-3014.
27. Green, A. R., T. Lints, J. Visvader, R. Harvey, and C. G. Begley. 1992. SCL is coexpressed with GATA-1 in hemopoietic cells but is also expressed in developing brain. Oncogene 7:653-660.
28. Grueneberg, D. A., S. Natesan, C. Alexandre, and M. Z. Gilman. 1992. Human and Drosophila homeodomain proteins that enhance the DNA-binding activity of serum response factor. Science 257:1089-1095.
29. Hill, J., K. A. Donald, and D. E. Griffiths. 1991. DMSO-enhanced whole cell yeast transformation. Nucleic Acids Res. 19:5791.
30. Hollenberg, S. M., P. F. Cheng, and H. Weintraub. 1993. Use of a conditional MyoD transcription factor in studies of MyoD trans-activation and muscle determination. Proc. Natl. Acad. Sci. USA 90:8028-8032.
31. Hollenberg, S. M., and H. Weintraub. Unpublished data.
32. Hopwood, N. D., A. Pluck, and J. B. Gurdon. 1989. A Xenopus mRNA related to Drosophila twist is expressed in response to induction in the mesoderm and the neural crest. Cell 59:893-903.
33. Hsu, H. L., L. Huang, J. T. Tsan, W. Funk, W. E. Wright, J. S. Hu, R. E. Kingston, and R. Baer. 1994. Preferred sequences for DNA recognition by the TAL1 helix-loop-helix proteins. Mol. Cell. Biol. 14:1256-1265.
34. Hwang, L. Y., M. Siegelman, L. Davis, N. Oppenheimer-Marks, and R. Baer. 1993. Expression of the TAL1 proto-oncogene in cultured endothelial cells and blood vessels of the spleen. Oncogene 8:3043-3046.
35. Ish-Horowicz, D., and S. M. Pinchin. 1987. Pattern abnormalities induced by ectopic expression of the Drosophila gene hairy are associated with repression of ftz transcription. Cell 51:405-415.
36. Ishibashi, M., Y. Sasai, S. Nakanishi, and R. Kageyama. 1993. Molecular characterization of HES-2, a mammalian helix-loop-helix factor structurally related to Drosophila hairy and Enhancer of split. Eur. J. Biochem. 215: 645-652.
37. Kallianpur, A. R., J. E. Jordan, and S. J. Brandt. 1994. The SCL/TAL-1 gene is expressed in progenitors of both the hematopoietic and vascular systems during embryogenesis. Blood 83:1200-1208.
38. Knust, E., K. A. Bremer, H. Vassin, A. Ziemer, U. Tepass, and J. A. Campos-Ortega. 1987. The enhancer of split locus and neurogenesis in Drosophila melanogaster. Dev. Biol. 122:262-273.
39. Lee, J., S. M. Hollenberg, L. Snider, D. Turner, N. Lipnick, and H. Weintraub. NeuroD, a new basic helix-loop-helix protein, can convert Xenopus ectoderm into neurons. Science, in press.
40. Lillie, J. W., and M. R. Green. 1989. Transcription activation by the adenovirus E1a protein. Nature (London) 338:39-44.
41. Ma, P. C., M. A. Rould, H. Weintraub, and C. O. Pabo. 1994. Crystal structure of MyoD bHLH domain-DNA complex: perspectives on DNA recognition and implications for transcriptional activation. Cell 77:451-459.
42. Murre, C., P. S. McCaw, and D. Baltimore. 1989. A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins. Cell 56:777-783.
43. Olson, E. N., and W. H. Klein. 1994. bHLH factors in muscle development: dead lines and commitments, what to leave in and what to leave out. Genes Dev. 8:1-8.
44. Patanjali, S. R., S. Parimoo, and S. M. Weissman. 1991. Construction of a uniform-abundance (normalized) cDNA library. Proc. Natl. Acad. Sci. USA 88:1943-1947.
45. Quertermous, E. E., H. Hidai, M. A. Blanar, and T. Quertermous. 1994. Cloning and characterization of a basic helix-loop-helix protein expressed in early mesoderm and the developing somites. Proc. Natl. Acad. Sci. USA 91:7066-7070.
46. Quong, M. W., M. E. Massari, R. Zwart, and C. Murre. 1993. A new transcriptional-activation motif restricted to a class of helix-loop-helix proteins is functionally conserved in both yeast and mammalian cells. Mol. Cell. Biol. 13:792-800.
47. Roberts, V. J., R. Steenbergen, and C. Murre. 1993. Localization of E2A mRNA expression in developing and adult rat tissues. Proc. Natl. Acad. Sci. USA 90:7583-7587.
48. Rupp, R. A., and H. Weintraub. 1991. Ubiquitous MyoD transcription at the midblastula transition precedes induction-dependent MyoD expression in presumptive mesoderm of X. laevis. Cell 65:927-937.
49. Sadowski, I., and M. Ptashne. 1989. A vector for expressing GAL4(1-147) fusions in mammalian cells. Nucleic Acids Res. 17:7539.
50. Schiestl, R. H., and R. D. Gietz. 1989. High efficiency transformation of intact yeast cells using single stranded nucleic acids as a carrier. Curr. Genet. 16:339-346.
51. Seuss, D. 1957. The cat in the hat. Houghton Mifflin, Boston.
52. Silver, P. A., R. Brent, and M. Ptashne. 1986. DNA binding is not sufficient for nuclear localization of regulatory proteins in Saccharomyces cerevisiae. Mol. Cell. Biol. 6:4763-4766.
53. Staudinger, J., M. Perry, S. J. Elledge, and E. N. Olson. 1993. Interactions among vertebrate helix-loop-helix proteins in yeast using the two-hybrid system. J. Biol. Chem. 268:4608-4611.
54. Sun, X. H., and D. Baltimore. 1991. An inhibitory domain of E12 transcription factor prevents DNA binding in E12 homodimers but not in E12 heterodimers. Cell 64:459-470.
55. Sun, X. H., N. G. Copeland, N. A. Jenkins, and D. Baltimore. 1991. Id proteins Id1 and Id2 selectively inhibit DNA binding by one class of helix-loop-helix proteins. Mol. Cell. Biol. 11:5603-5611.
56. Thayer, M. J., and H. Weintraub. 1993. A cellular factor stimulates the DNA-binding activity of MyoD and E47. Proc. Natl. Acad. Sci. USA 90: 6483-6487.
57. Turner, D., and R. Rupp. Unpublished data.
58. Van Antwerp, M. E., D. G. Chen, C. Chang, and E. V. Prochownik. 1992. A point mutation in the MyoD basic domain imparts c-Myc-like properties. Proc. Natl. Acad. Sci. USA 89:9010-9014.
59. Visvader, J., and C. B. Begley. 1991. Helix-loop-helix genes translocated in lymphoid leukemia. Trends Biochem. Sci. 16:330-333.
60. Vojtek, A. B., S. M. Hollenberg, and J. A. Cooper. 1993. Mammalian Ras interacts directly with the serine/threonine kinase Raf. Cell 74:205-214.
61. Wang, Z., and D. D. Brown. 1991. A gene expression screen. Proc. Natl. Acad. Sci. USA 88:11505-11509.
62. Weintraub, H., R. Davis, D. Lockshon, and A. Lassar. 1990. MyoD binds cooperatively to two sites in a target enhancer sequence: occupancy of two sites is required for activation. Proc. Natl. Acad. Sci. USA 87:5623-5627.
63. Weintraub, H. 1993. The MyoD family and myogenesis: redundancy, networks, and thresholds. Cell 75:1241-1244.
64. Wolf, C., C. Thisse, C. Stoetzel, B. Thisse, P. Gerlinger, and F. Perrin-Schmitt. 1991. The M-twist gene of Mus is expressed in subsets of mesodermal cells and is closely related to the Xenopus X-twi and the Drosophila twist genes. Dev. Biol. 143:363-373.
65. Wright, W. E., M. Binder, and W. Funk. 1991. Cyclic amplification and selection of targets (CASTing) for the myogenin consensus binding site. Mol. Cell. Biol. 11:4104-4110.
66. Wright, W. E., D. A. Sassoon, and V. K. Lin. 1989. Myogenin, a factor regulating myogenesis, has a domain homologous to MyoD. Cell 56:607-617.
67. Xia, Y., L. Brown, C. Y. Yang, J. T. Tsan, M. J. Siciliano, R. I. Espinosa, M. M. Le-Beau, and R. J. Baer. 1991. TAL2, a helix-loop-helix gene activated by the (7;9)(q34;q32) translocation in human T-cell leukemia. Proc. Natl. Acad. Sci. USA 88:11416-11420.
68. Young, D., M. Riggs, J. Field, A. Vojtek, D. Broek, and M. Wigler. 1989. The adenylyl cyclase gene from Schizosaccharomyces pombe. Proc. Natl. Acad. Sci. USA 86:7989-7993.
69. Zhuang, Y., and H. Weintraub. Unpublished data.