Catalytic domain of human immunodeficiency virus type 1 integrase: Identification of a soluble mutant by systematic replacement of hydrophobic residues

Proceedings of the National Academy of Sciences of the United States of America

Volumn 92, Issue 13, 1995, Pages 6057-6061

  Jenkins, Timothy M ^a   Hickman, Alison B ^a   Dyda, Fred ^a   Ghirlando, Rodolfo ^a   Davies, David R ^a   Craigie, Robert ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS DNA;

ARTICLE; CATALYSIS; DNA STRAND; DNA TRANSFER; ENZYME ACTIVITY; GENOME; HUMAN IMMUNODEFICIENCY VIRUS 1; HYDROPHOBICITY; PRIORITY JOURNAL; SOLUBILITY; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; BINDING SITES; CATALYSIS; CHROMATOGRAPHY, GEL; COMPARATIVE STUDY; DNA NUCLEOTIDYLTRANSFERASES; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME STABILITY; HISTIDINE; HIV-1; INTEGRASE; MACROMOLECULAR SYSTEMS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; POINT MUTATION; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; SEQUENCE TAGGED SITES; SOLUBILITY; SUPPORT, U.S. GOV'T, P.H.S.; VIRUS INTEGRATION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0029017919     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.92.13.6057     Document Type: Article

References (32)