(+)-cis-4,5,7a,8,9,10,11,11a-Octahydro-7H-10-methylmdolo[1,7-bc][2,6]- naphthyridine: A 5-HT2C/2B Receptor Antagonist with Low 5-HT2a Receptor Affinity

Journal of Medicinal Chemistry

Volumn 38, Issue 1, 1995, Pages 28-33

  Nozulak, Joachim ^a   Kalkman, Hans O ^a   Floersheim, Philipp ^a   Hoyer, Daniel ^a   Schoeffter, Philipp ^a   Buerki, Hans R ^a  

^a Preclinical Research   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 4 IODO 2,5 DIMETHOXYAMPHETAMINE; 4,5,7A,8,9,10,11,11A OCTAHYDRO 7H 10 METHYLINDOLO[1,7 BC][2,6]NAPHTHYRIDINE; 6 CHLORO 2 (1 PIPERAZINYL)PYRAZINE; 8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; ALUMINUM DERIVATIVE; BEMESETRON; CARBACHOL; CINANSERIN; CLONIDINE; CORTICOTROPIN; CYANOIODOPINDOLOL; INOSITOL PHOSPHATE; KETANSERIN; MESULERGINE; MIANSERIN; NAPHTHYRIDINE DERIVATIVE; PHOSPHATIDYLINOSITOL; PRAZOSIN; RITANSERIN; SEROTONIN; SEROTONIN 1C RECEPTOR; SEROTONIN 2 RECEPTOR; SEROTONIN 2A RECEPTOR; SEROTONIN 2B RECEPTOR; SEROTONIN ANTAGONIST; SPIPERONE; TROPISETRON; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHOROID PLEXUS; CONTROLLED STUDY; CYCLIZATION; DOSE RESPONSE; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; HYPOPHAGIA; MALE; MUSCLE CONTRACTION; NONHUMAN; PHOSPHOINOSITIDE METABOLISM; RAT; RECEPTOR AFFINITY; STOMACH FUNDUS; SUBCUTANEOUS DRUG ADMINISTRATION; SWINE;

ANIMAL; KINETICS; MALE; NAPHTHYRIDINES; RATS; RATS, INBRED WKY; RATS, SPRAGUE-DAWLEY; SEROTONIN ANTAGONISTS;

EID: 0029016056     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00001a007     Document Type: Article

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