SCOPUS 정보 검색 플랫폼

Volumn 36, Issue 20, 1995, Pages 3489-3490

Simple one-step synthesis of 3-bromo- and 3,8-dibromo-1,10-phenanthroline: Fundamental building blocks in the design of metal chelates

Author keywords

[No Author keywords available]

Indexed keywords

3 BROMO 1,10 PHENANTHROLINE; 3,8 DIBROMO 1,10 PHENANTHROLINE; ORGANOBROMINE DERIVATIVE; PHENANTHROLINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG SYNTHESIS; REACTION ANALYSIS;

EID: 0029014808 PISSN: 00404039 EISSN: None Source Type: Journal
DOI: 10.1016/0040-4039(95)00572-T Document Type: Article

Times cited : (86)

References (8)

1
- 11644265062
- For a recent review that summarizes recent applications of phenanthroline ligands in bioorganic chemistry, molecular recognition and supramoleuclar chemistry, see:
- (1994) Chem. Soc. Rev. , vol.23 , pp. 327-334
- Sammes¹ Yahioglu²

2
- 0000800237
- For the multi-step syntheses of bromo derivatives of 1,10-phenanthroline using the Skraup reaction, see:
- (1951) J. Org. Chem. , vol.16 , pp. 941-945
- Case¹

3
- 0010632916
- For a monograph, see:, (Vol. 47 of Adv. Heterocycl. Chem.), Academic Press, San Diego
- (1990) Electrophilic Substitution of Heterocycles: Quantitative Aspects
- Katritzky¹ Taylor²

4
- 84914017954
- For an early review, see:, C.F.H. Allen, Interscience Publishing, Inc, New York
- (1958) The Chemistry of Heterocyclic Compounds , pp. 386-456
- Graham¹

5
- 0001683346
- Polyhalogenation of nitrogen containing heterocyclic compounds. III. Polybromo-1, 10-phenanthrolines
- A direct bromination reaction that gives low yields of di-, tri- and tetrabrominated phenanthrolines and traces of the 3- and 5-bromo derivatives has been reported:
- (1978) Journal f�r Praktische Chemie , vol.320 , pp. 172-175
- Denes¹ Chira²

6
- 0015831499
- (1973) J. Heterocyclic Chem. , vol.10 , pp. 409-410
- Kress¹ Costantino²

7
- 84914010391
- 3) δ 9.20 (d, J=2.2 Hz, 2H, H2,9), 8.44, d, J=2.2 Hz, [[Truncated]]

8
- 84914010390
- Variations of the amount of bromine, reaction time, or temperature influence the outcome of the reaction. Attempts to push the reaction to completion or to higher conversions usually result in higher yields of 3 but at the same time lead to the generation of various other brominated derivatives. Under the present conditions, ca. 90 % of crude phenanthroline containing products can be accounted for as unsubstituted phenanthroline, 2 and 3. The remaining 10% contains several other brominated by-products (5-bromo-, 3,5,8-tribromo- and 3,5,6,8-tetrabromo-1,10-phenanthroline) that can be removed by column chromatography.

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.