The catalytic mechanism of Fpg protein: Evidence for a Schiff base intermediate and amino terminus localization of the catalytic site

Journal of Biological Chemistry

Volumn 270, Issue 19, 1995, Pages 11671-11677

  Tchou, Julia ^a   Grollman, Arthur P ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACRONICTA LEPORINA; ESCHERICHIA COLI;

POLYDEOXYRIBONUCLEOTIDE SYNTHASE; SCHIFF BASE;

AMINO TERMINAL SEQUENCE; ARTICLE; CATALYSIS; DNA BINDING; DNA PROTEIN COMPLEX; ENZYME MECHANISM; ENZYME SUBSTRATE; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTON TRANSPORT; STRUCTURE ACTIVITY RELATION;

BASE SEQUENCE; BINDING SITES; CARRIER PROTEINS; COMPARATIVE STUDY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ESCHERICHIA COLI; FACTOR XA; GENES, BACTERIAL; GENOTYPE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; N-GLYCOSYL HYDROLASES; OLIGODEOXYRIBONUCLEOTIDES; PEPTIDE FRAGMENTS; PHENOTYPE; RECOMBINANT FUSION PROTEINS; SCHIFF BASES; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0029013243     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.270.19.11671     Document Type: Article

References (31)

1. Bailly, V., Verly, W. G., O'Connor, T. R., and Laval, J. (1989) Biochem. J. 262, 581-589
2. Bodepudi, V., Shibutani, S., and Johnson, F. (1992) Chem. Res. Toxicol. 5, 608-617
3. Boiteux, S., O'Connor, T. R., and Laval, J. (1987) EMBO J. 6, 3177-3183
4. Boiteux, S., O'Connor, T. R., Lederer, F., Gouyette, A., and Laval, J. (1990) J. Biol. Chem. 265, 3916-3922
5. Boiteux, S., Gajewski, E., Laval, J., and Dizdaroglu, M. (1992) Biochemistry 31, 106-110
6. Borch, R. F., Bernstein, M. D., and Durst, H. D. (1971) J. Am. Chem. Soc. 93, 2897-2904
7. Breimer, L. H. (1984) Nucleic Acids Res. 12, 6359-6367
8. Chetsanga, C. J., and Frenette, G. P. (1983) Carcinogenesis 4, 997-1000
9. Chetsanga, C. J., and Lindahl, T. (1979) Nucleic Acids Res. 6, 3673-3684
10. Dodson, M. L., Schrock, R. D., III, Lloyd, R. S. (1993) Biochemistry 32, 8284-8290
11. Fersht, A. (ed) (1985)Enzyme Structure and Mechanism, 2nd Ed., pp. 69-75, W. H. Freeman, New York
12. Graves, R. J., Felzenszwalb, I., Laval, J., and O'Connor, T. R. (1992) J. Biol. Chem. 267, 14429-14435
13. Hanahan, D. (1983) J. Mol. Biol. 166, 557-580
14. Hatahet, Z., Kow, Y. W., Purmal, A. A., Cunningham, R. P., and Wallace, S. S. (1994) J. Biol. Chem. 269, 18814-18820
15. Kow, Y. W., and Wallace, S. S. (1987) Biochemistry 26, 8200-8206
16. Laemmli, U. K. (1970) Nature 227, 680-685
17. Laval, J., Boiteux, S., and O'Connor, T. R. (1990) Mutat. Res. 233, 73-79
18. Nagai, K., and Thogersen, H. C. (1987) Methods Enzymol. 153, 461-481
19. O'Connor, T. R., and Laval, J. (1989) Proc. Natl. Acad. Sci. U. S. A. 86, 5222-5226
20. O'Connor, T. R., Graves, R. J., de Murcia, G., Castaing, B., and Laval, J. (1993) J. Biol. Chem. 268, 9063-9070
21. Oleykowski, C. A., Mayernik, J. A., Lim, S. E., Groopman, J. D., Grossman, L., Wogan, G. N., and Yeung, A. T. (1993) J. Biol. Chem. 268, 7990-8002
22. Sancar, A., and Sancar, G. B. (1988) Annu. Rev. Biochem. 57, 29-67
23. Sanger, F., Miklen, S., and Coulson, A. R. (1977) Proc. Natl. Acad. Sci. U. S. A. 74, 5463-5467
24. Schrock, R. D., III, and Lloyd, R. S. (1991) J. Biol. Chem. 266, 17631-17639
25. Schrock, R. D., III, and Lloyd, R. S. (1993) J. Biol. Chem. 268, 880-886
26. Takeshita, M., Chang, C.-N., Johnson, F., Will, S., and Grollman, A. P. (1987) J. Biol. Chem. 262, 10171-10179
27. Tchou, J., and A. P. Grollman (1993) Mutat. Res. 299, 277-287
28. Tchou, J., Kasai, H., Shibutani, S. Chung, M.-H., Laval, J., Grollman, A. P., and Nishimura, S. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 4690-4694
29. Tchou, J., Michaels, M. L., Miller, J. H., and Grollman, A. P. (1993) J. Biol. Chem. 268, 26738-26744
30. Tchou, J., Bodepudi, V., Shibutani, S., Antoshechkin, I., Miller, J., Grollman, A. P., and Johnson, F. (1994) J. Biol. Chem. 269, 15318-15324
31. Weiss, B., and Grossman, L. (1987) Adv. Enzymol. 60, 1-34