메뉴 건너뛰기




Volumn 5, Issue 3, 1995, Pages 342-349

Get receptive to metabotropic glutamate receptors

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMATE RECEPTOR; GLUTAMIC ACID; GUANINE NUCLEOTIDE BINDING PROTEIN; LIGAND; METABOTROPIC RECEPTOR;

EID: 0029012608     PISSN: 09594388     EISSN: None     Source Type: Journal    
DOI: 10.1016/0959-4388(95)80047-6     Document Type: Article
Times cited : (128)

References (60)
  • 1
    • 0027476024 scopus 로고
    • A synaptic model of memory: long-term potentiation in the hippocampus
    • (1993) Nature , vol.361 , pp. 31-39
    • Bliss1    Collingridge2
  • 2
    • 0027938848 scopus 로고
    • Metabotropic glutamate receptors: synaptic transmission, modulation, and plasticity
    • of special interest, General review on recently discovered physiological roles of mGluRs, with a special emphasis on the role of mGluR6 in the retina, the role of mGluR2 in the accessory olfactory bulb and olfactory memory, and the role of mGluR1 in cerebellar LTD.
    • (1994) Neuron , vol.13 , pp. 1031-1037
    • Nakanishi1
  • 3
    • 0028912822 scopus 로고
    • The metabotropic glutamate receptors: structure and functions
    • of special interest, Exhaustive review on the discovery, structure, transduction mechanisms and physiological roles of mGluRs.
    • (1995) Neuropharmacology , vol.34 , pp. 1-26
    • Pin1    Duvoisin2
  • 6
    • 0027955170 scopus 로고
    • Molecular characterization of a new metabotropic glutamate receptor mGluR7 coupled to inhibitory cyclic AMP signal transduction.
    • of special interest, Cloning of mGluR7, a receptor negatively coupled to adenylyl cyclase with a surprisingly low apparent affinity for l-AP4, l-SOP and glutamate. This receptor is widely distributed in the brain, with higher expression in the cerebral cortex, thalamus, hippocampus, olfactory bulb and colliculi.
    • (1994) J Biol Chem , vol.269 , pp. 1231-1236
    • Okamoto1    Hori2    Akazawa3    Hayashi4    Shigemoto5    Mizuno6    Nakanishi7
  • 7
    • 0028968702 scopus 로고
    • A novel metabotropic glutamate receptor expressed in the retina and olfactory bulb
    • of special interest, Cloning of the mouse mGluR8, an mGluR negatively coupled to adenylyl cyclase and activated by l-AP4 that is widely distributed in the brain.
    • (1995) J Neurosci , vol.15 , pp. 3075-3083
    • Duvoisin1    Zhang2    Ramonell3
  • 8
    • 0028207306 scopus 로고
    • Cloning an expression of a new member of the l-2-amino-4-phosphonobutyric acid-class of metabotropic glutamate receptors
    • of special interest, Cloning of mGluR7. Same results as those reported by Okamoto et al. [6]. No antagonistic effects of MCPG was observed.
    • (1994) Mol Pharmacol , vol.45 , pp. 367-372
    • Saugstad1    Kinzie2    Mulvihill3    Segerson4    Westbrook5
  • 9
    • 0027992583 scopus 로고
    • Phenylglycine derivatives as antagonists of metabotropic glutamate receptors
    • of special interest, A comprehensive review on the different effects of phenylglycine derivatives, which are competitive antagonists for mGluRs.
    • (1994) Trends Neurosci , vol.15 , pp. 333-342
    • Watkins1    Collingridge2
  • 10
    • 0028350739 scopus 로고
    • Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor subtypes
    • of special interest, A complete analysis of the effect of various phenylglycine derivatives on cloned mGluR subtypes.
    • (1994) J Neurosci , vol.14 , pp. 3370-3377
    • Hayashi1    Sekiyama2    Nakanishi3    Jane4    Sunter5    Birse6    Udvarhelyi7    Watkins8
  • 11
    • 0028177284 scopus 로고
    • Action of phenylglycine analogs at subtypes of the metabotropic glutamate receptor family
    • (1994) Eur J Pharmacol , vol.267 , pp. 77-84
    • Thomsen1    Boel2    Suzdak3
  • 12
    • 0029043591 scopus 로고
    • Molecular, functional and pharmacological characterization of the metabotropic glutamate receptor type 5 splice variants: comparison with mGluR1
    • (1995) J Neurosci , vol.15 , pp. 3970-3981
    • Joly1    Gomeza2    Brabet3    Curry4    Bockaert5    Pin6
  • 13
    • 0028245013 scopus 로고
    • Actions of two new antagonists showing selectivity for different subtypes of metabotropic glutamate receptor in the neonatal rat spinal cord
    • (1994) Br J Pharmacol , vol.112 , pp. 809-816
    • Jane1    Jones2    Pook3    Tse4    Watkins5
  • 14
    • 0027295942 scopus 로고
    • The ligand-binding domain in metabotropic glutamate receptors is related to bacterial periplasmic binding proteins
    • of outstanding interest, The amino-terminal extracellular domain of mGluR1 is shown to share sequence homology with the bacterial periplasmic protein family. A model for the glutamate-binding site of mGluR1 was proposed, and used to identify two residues that play a critical role in the binding of glutamate. This paper also suggested that similar structural domains may be responsible for agonist binding in ionotropic glutamate receptor subunits.
    • (1993) Neuron , vol.11 , pp. 41-52
    • O'Hara1    Sheppard2    Thøgersen3    Venezia4    Haldeman5    McGrane6    Houamed7    Thomsen8    Gilbert9    Mulvihill10
  • 17
    • 0027787680 scopus 로고
    • 2+-sensing receptor gene cause familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism
    • 2+-sensing receptor gene are characterized in patients with familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism. One of these mutations is found in the third intracellular loop of the receptor and generates an apparently inactive receptor.
    • (1993) Cell , vol.75 , pp. 1297-1303
    • Pollak1    Brown2    Chou3    Hebert4    Marx5    Steinmann6    Levi7    Seidman8    Seidman9
  • 18
    • 0028596211 scopus 로고
    • N-Glycosylation site tagging suggests a three transmembrane domain topology for the glutamate receptor GluR1
    • (1994) Neuron , vol.13 , pp. 1331-1343
    • Hollmann1    Maron2    Heinemann3
  • 19
    • 0028819612 scopus 로고
    • Topology profile for a glutamate receptor: three transmembrane domains and a channel-lining reentrant membrane loop
    • (1995) Neuron , vol.14 , pp. 373-383
    • Bennett1    Dingledine2
  • 20
    • 0028559605 scopus 로고
    • Agonist selectivity of glutamate receptors is specified by two domains structurally related to bacterial amino acid-binding proteins
    • of outstanding interest, By constructing chimeric receptors from the AMPA receptor subunit GluR3 and the kainate receptor subunit GluR6, these authors show that the agonist selectivity of these subunits is determined by two domains separated by what was initially proposed as three transmembrane domains. A new model for the topology of the subunit with only three transmembrane domains is proposed. A model for the tertiary structure of the glutamate-binding site based on its homology with bacterial periplasmic proteins is presented.
    • (1994) Neuron , vol.13 , pp. 1345-1357
    • Stern-Bach1    Bettler2    Hartley3    Sheppard4    O'Hara5    Heinemann6
  • 21
    • 0028284469 scopus 로고
    • Mutational analysis of the glycine-binding site of the NMDA receptor: structural similarity with bacterial amino acid-binding proteins
    • of special interest, Based on the characterization of the residues involved in the glycine-binding site of the glycine receptor subunits, point mutations affecting the glycine binding to the NMDA-R1 subunit are described. This is the first study to support the proposal of O'Hara et al. [14] that the agonist-binding sites in glutamate receptor subunits may be homologous to the bacterial periplasmic proteins. A model for the glycine-binding site in the NMDA-R1 subunit is proposed.
    • (1994) Neuron , vol.12 , pp. 1291-1300
    • Kuryatov1    Laube2    Betz3    Kuhse4
  • 22
    • 0028012253 scopus 로고
    • Domains involved in the specificity of G protein activation in phospholipase C coupled metabotropic glutamate receptor
    • of special interest, By constructing chimeric receptors from the adenylyl cyclase coupled mGluR3 and the PLC-coupled mGluR1, the regions involved in the specific coupling to PLC in mGluR1 were identified.
    • (1994) EMBO J , vol.13 , pp. 342-348
    • Pin1    Joly2    Heinemann3    Bockaert4
  • 23
    • 0026168057 scopus 로고
    • G proteins and G-protein-coupled receptors: structure, function and interactions
    • (1991) Curr Opin Neurobiol , vol.1 , pp. 32-42
    • Bockaert1
  • 24
  • 27
    • 0027475709 scopus 로고
    • Differential localization of phosphoinositide-linked metabotropic glutamate receptor (mGluR1) and the inositol 1,4,5-triphosphate receptor in rat brain
    • of special interest, Using Western blots and an antibody against the amino-terminal domain of mGluR1 (which reacts with all mGluR1 splice variants), the authors show that the major mGluR1 form in the striatum is a short form, either mGluR1b or mGluR1c. Electron microscopy detection of the protein in the striatum revealed labeling of nerve terminals, in contrast to what has been described with an antibody specific for the long-form mGluR1 splice variant, mGluR1a (see Baude et al. [44]).
    • (1993) J Neurosci , vol.13 , pp. 2001-2012
    • Fotuhi1    Sharp2    Glatt3    Hwang4    Von Krosigk5    Snyder6    Dawson7
  • 29
    • 0026659344 scopus 로고
    • l-AP4 inhibits calcium currents and synaptic transmission via a G-protein-coupled glutamate receptor
    • (1992) J Neurosci , vol.12 , pp. 2043-2050
    • Trombley1    Westbrook2
  • 30
    • 0028218968 scopus 로고
    • Developmentally regulated postsynaptic localization of a metabotropic glutamate receptor in rat rod bipolar cells
    • of special interest, An immunocytochemical and immunoelectron microscopy study showing the restricted localization of mGluR6 at the postsynaptic site of the rat rod bipolar cell. This specialization is developmentally regulated; mGluR6 is initially distributed in both the soma and dendrites, and is finally concentrated on the postsynaptic site.
    • (1994) Cell , vol.77 , pp. 361-369
    • Nomura1    Shigemoto2    Nakamura3    Okamoto4    Mizuno5    Nakanishi6
  • 31
    • 0027232329 scopus 로고
    • Molecular characterization of a novel retinal metabotropic glutamate receptor mGluR6 with a high agonist selectivity for l-2-amino-4-phosphonobutyrate
    • of special interest, Cloning of a retina-specific mGluR, mGluR6, that is activated by l-AP4 and l-SOP and that inhibits cAMP formation.
    • (1993) J Biol Chem , vol.268 , pp. 11868-11873
    • Nakajima1    Iwakabe2    Akazawa3    Nawa4    Shigemoto5    Mizuno6    Nakanishi7
  • 32
    • 0028036657 scopus 로고
    • The metabotropic glutamate receptor types 2/3 inhibit L-type calcium channels via a pertussis toxin-sensitive G-protein in cultured cerebellar granule cells
    • (1994) J Neurosci , vol.14 , pp. 7067-7076
    • Chavis1    Shinozaki2    Bockaert3    Fagni4
  • 33
    • 0027732539 scopus 로고
    • Role of a metabotropic glutamate receptor in synaptic modulation in the accessory olfactory bulb
    • of outstanding interest, Electron microscopy localization of mGluR2 revealed a localization of this receptor at dendrodendritic synapses between granule cells and mitral cells in the accessory olfactory bulb. Using DCG-IV, which is shown to be a high-affinity agonist at mGluR2, the authors revealed that mGluR2 depressed the GABA-mediated inhibitory postsynaptic current on mitral cells.
    • (1993) Nature , vol.366 , pp. 687-690
    • Hayashi1    Momiyama2    Takahashi3    Ohishi4    Ogawa-Meguro5    Shigemoto6    Mizuno7    Nakanishi8
  • 34
    • 0028088017 scopus 로고
    • Immunohistochemical localization of metabotropic glutamate receptors, mGluR2 and mGluR3, in rat cerebellar cortex
    • of special interest, Immunoreactivity to mGluR2 and mGluR3 is shown to be present in cell bodies, dendrites and axon terminals of Golgi cells, as well as in presumed glial processes. Golgi axon terminals with mGluR2/3 immunoreactivity were often encountered in the vicinity of glutamatergic mossy fiber terminals. It is proposed that glutamate released from mossy fibers during strong synaptic activity may diffuse into the intercellular space and reach the Golgi axon terminals, probably depressing the synaptic transmission at these synapses.
    • (1994) Neuron , vol.13 , pp. 55-66
    • Ohishi1    Ogawa-Meguro2    Shigemoto3    Kaneko4    Nakanishi5    Mizuno6
  • 35
    • 0028850892 scopus 로고
    • Metabotropic glutamate receptor (mGluR)-mediated potentiation of cyclic AMP responses does not require phosphoinositide hydrolysis: mediation by a group II-like mGluR
    • (1995) J Neurochem , vol.64 , pp. 592-599
    • Winder1    Conn2
  • 36
    • 0028362318 scopus 로고
    • Potentiation of cAMP responses by metabotropic glutamate receptors depresses excitatory synaptic transmission by a kinase-independent mechanism
    • (1994) Neuron , vol.12 , pp. 1121-1129
    • Gereau1    Conn2
  • 37
    • 0028222023 scopus 로고
    • A cyclic AMP-dependent form of associative synaptic plasticity induced by coactivation of beta-adrenergic receptors and metabotropic glutamate receptors in rat hippocampus.
    • (1994) J Neurosci , vol.14 , pp. 3310-3318
    • Gereau1    Conn2
  • 38
    • 0028108923 scopus 로고
    • CREB: a mediator of long-term memory from mollusks to mammals
    • (1994) Cell , vol.79 , pp. 5-8
    • Frank1    Greenberg2
  • 39
    • 0026564333 scopus 로고
    • Inhibition of calcium channels in rat CA3 pyramidal neurons by a metabotropic glutamate receptor
    • (1992) J Neurosci , vol.12 , pp. 4358-4371
    • Swartz1    Bean2
  • 40
    • 0028878058 scopus 로고
    • Facilitatory coupling between a glutamate metabotropic receptor and dihydropyridine-sensitive calcium channels in cultured cerebellar granule cells
    • 2+.
    • (1995) J Neurosci , vol.15 , pp. 135-143
    • Chavis1    Nooney2    Bockaert3    Fagni4    Feltz5    Bossu6
  • 43
    • 0029002053 scopus 로고
    • Distribution of metabotropic glutamate receptor mGluR5 immunoreactivity in rat brain
    • of special interest, Immunolocalization of mGluR5. Electron microscopy studies revealed the presence of mGluR5 at the postsynaptic site. Some axon terminals were also labeled, indicating that mGluR5 may also be presynaptically localized.
    • (1995) J Comp Neurol
    • Romano1    Sesma2    MacDonald3    O'Malley4    Van den Pol5    Olney6
  • 44
    • 0027520283 scopus 로고
    • The metabotropic glutamate receptor (mGluR1α) is concentrated at perisynaptic membrane of neuronal subpopulations as detected by immunogold reaction
    • of outstanding interest, Using a specific antibody and electron microscopic immunometal detection, mGluR1α is shown to be localized at the periphery of postsynaptic densities of type I synapses in both the cerebellum and the hippocampus. No immunoreactivity is observed in axon terminals.
    • (1993) Neuron , vol.11 , pp. 771-787
    • Baude1    Nusser2    Roberts3    Mulvihill4    McIlhinney5    Somogyi6
  • 46
    • 0028310856 scopus 로고
    • Activation of metabotropic glutamate receptors differentially affects two classes of hippocampal interneurons and potentiates excitatory synaptic transmission
    • of special interest, First electrophysiological evidence for a presynaptic potentiation induced by mGluR agonists.
    • (1994) J Neurosci , vol.14 , pp. 4433-4445
    • McBain1    Dichiara2    Kauer3
  • 48
    • 0027967167 scopus 로고
    • Induction of an olfactory memory by the activation of a metabotropic glutamate receptor
    • of outstanding interest, Female mice memorize the male pheromone at mating, and exposure of the pregnant mice to a different male pheromone evokes pregnancy block. This olfactory memory, known as the ‘Bruce effect’, results from a sustained enhancement of norepinephrine release after mating, which inhibits GABA release from granule cells in the accessory olfactory bulb (AOB). Because activation of mGluR2 also leads to a depression of the GABA inhibitory postsynaptic current at these synapses (see Hayashi et al. [33]), the effect of specific mGluR2 agonists directly applied in the AOB on the ‘Bruce effect’ was examined. This was shown to favour the memorization of male pheromones without mating.
    • (1994) Science , vol.265 , pp. 262-264
    • Kaba1    Hayashi2    Higuchi3    Nakanishi4
  • 49
    • 0028208421 scopus 로고
    • Long-term synaptic depression in the mammalian brain
    • of special interest, Comprehensive review on LTP.
    • (1994) Neuron , vol.12 , pp. 457-472
    • Linden1
  • 50
    • 0028284466 scopus 로고
    • Antibodies inactivating mGluR1 metabotropic glutamate receptor block long-term depression in cultured Purkinje cells
    • of special interest, A polyclonal antibody directed against the amino-terminal domain of mGluR1 was shown to inhibit the activity of this receptor. This antibody is shown to inhibit the LTD of the AMPA current induced by application of glutamate in conjunction with Purkinje cell depolarization.
    • (1994) Neuron , vol.12 , pp. 1245-1255
    • Shigemoto1    Abe2    Nomura3    Nakanishi4    Hirano5
  • 51
    • 0027997686 scopus 로고
    • Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1
    • of outstanding interest, It is shown that mGluR1 knock-out mice are ataxic, and are impaired in spatial learning capacity, as revealed using the Morris water maze test. Electrophysiological studies revealed no modification in the LTP at the Schaffer collateral—CA1 synapses, but a decrease in the LTP at the mossy fiber—CA3 synapses in the mutant mice. In the cerebellum, a decrease in the LTD at parallel fiber-Purkinje cell synapses is observed.
    • (1994) Nature , vol.372 , pp. 237-243
    • Conquet1    Bashir2    Davies3    Daniel4    Ferraguti5    Bordi6    Franz-Bacon7    Reggiani8    Matarese9    Condé10
  • 52
    • 0028149789 scopus 로고
    • Deficient cerebellar long-term depression and impaired motor learning in mGluR1 mutant mice
    • 2+ currents are normal, no LTD can be induced in the cerebellum of mGluR1 knock-out mice. These mutant mice are ataxic and are impaired in motor coordination and associative learning of eyeblink responses.
    • (1994) Cell , vol.79 , pp. 377-388
    • Aiba1    Kano2    Chen3    Stanton4    Fox5    Herrup6    Zwingman7    Tonegawa8
  • 53
    • 0026637694 scopus 로고
    • Quisqualate metabotropic receptors modulate NMDA currents and facilitate induction of long-term potentiation through protein kinase C
    • (1992) Eur J Neurosci , vol.4 , pp. 500-505
    • Aniksztejn1    Otani2    Ben-Ari3
  • 55
    • 0027765543 scopus 로고
    • (RS)-α-Methyl-4-carboxyphenylglycine neither prevents induction of LTP nor antagonizes metabotropic glutamate receptors in CA1 hippocampal neurons
    • (1993) J Neurophysiol , vol.70 , pp. 2684-2689
    • Chinestra1    Aniksztejn2    Diabira3    Ben-Ari4
  • 56
    • 0028337693 scopus 로고
    • MCPG antagonizes metabotropic glutamate receptors but not long-term potentiation in the hippocampus
    • (1994) Eur J Neurosci , vol.6 , pp. 1050-1054
    • Manzoni1    Weisskop2    Nicoll3
  • 57
    • 0028287907 scopus 로고
    • A molecular switch activated by metabotropic glutamate receptors regulates induction of long-term potentiation
    • of outstanding interest, MCPG is shown to no longer inhibit LTP induction after a first LTP has been induced. It is proposed that MCPG turns on a molecular ‘switch’ that no longer needs to be activated for a second LTP. This mGluR-activated switch is input specific and can be turned off by a train of low frequency stimulation.
    • (1994) Nature , vol.368 , pp. 740-743
    • Bortolotto1    Bashir2    Davies3    Collingridge4
  • 58
    • 0028082151 scopus 로고
    • Long-lasting enhancement of NMDA receptor-mediated synaptic transmission by metabotropic glutamate receptor activation
    • of outstanding interest, It is shown that tetanic stimulation of the Schaffer collaterals induced a long-lasting potentiation of the NMDA component of the excitatory postsynaptic currents in the CA1 region of the hippocampus. This effect is probably mediated by mGluRs as it is reproduced by ACPD and greatly reduced in the presence of MCPG.
    • (1994) Nature , vol.367 , pp. 557-559
    • O'Connor1    Rowan2    Anwyl3
  • 59
    • 0028139045 scopus 로고
    • Reduced hippocampal long-term potentiation and context-specific deficit in associative learning in mGluR1 mutant mice
    • 2+ current induced by ACPD are not modified in the mutant mice indicating that these effects are mediated by other mGluR subtypes. The mutant mice show a moderate deficit in context-specific associative learning, while performing an associative fear conditioning test.
    • (1994) Cell , vol.79 , pp. 365-375
    • Aiba1    Chen2    Herrup3    Rosenmund4    Stevens5    Tonegawa6
  • 60
    • 0028181168 scopus 로고
    • (R,S)-α-Methyl-4-carboxyphenylglycine (MCPG) blocks spatial learning in rats and long-term potentiation in the dentate gyrus in vivo
    • (1994) Neurosci Lett , vol.167 , pp. 141-144
    • Riedel1    Wetzel2    Reymann3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.