Human lung carcinogen-dna adduct levels mediated by genetic polymorphisms in vivo

Journal of the National Cancer Institute

Volumn 87, Issue 12, 1995, Pages 902-907

  Kato, Shunji ^a   Bowman, Elise D ^a   Harrington, Anita M ^a   Blomeke, Brunhilde ^a   Shields, Peter G ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOGEN; COTININE; CYTOCHROME P450; GLUTATHIONE TRANSFERASE; GUANOSINE PHOSPHATE; NITROSAMINE; POLYCYCLIC AROMATIC HYDROCARBON;

ADOLESCENT; ADULT; AGED; ARTICLE; CANCER RISK; CIGARETTE SMOKING; DISEASE ASSOCIATION; DNA ADDUCT; ENVIRONMENTAL EXPOSURE; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; HUMAN TISSUE; LUNG CANCER; LUNG CARCINOGENESIS; MAJOR CLINICAL STUDY; MALE; TOBACCO;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BASE SEQUENCE; COTININE; CYTOCHROME P-450 ENZYME SYSTEM; DEOXYGUANINE NUCLEOTIDES; FEMALE; GLUTATHIONE TRANSFERASE; HUMAN; LUNG; MALE; MIDDLE AGE; MOLECULAR SEQUENCE DATA; POLYCYCLIC HYDROCARBONS; POLYMORPHISM (GENETICS); SMOKING;

EID: 0029009951     PISSN: 00278874     EISSN: None     Source Type: Journal    
DOI: 10.1093/jnci/87.12.902     Document Type: Article

References (42)

1. Shields PG, Harris CC: Molecular epidemiology and the genetics of environmental cancer. JAMA 266:681-687, 1991
2. Ayesh R, Idle JR, Ritchie JC, et al: Metabolic oxidation phenotypes as markers for susceptibility to lung cancer. Nature 312:169-170, 1984
3. Caporaso NE, Tucker MA, Hoover RN, et al: Lung cancer and the debriso- quine metabolic phenotype [see comment citations in Medline]. J Natl Cancer Inst 82:1264-1272, 1990
4. Amos Cl, Caporaso NE, Weston A: Host factors in lung cancer risk: a review of interdisciplinary studies. CEBP 1:505-513, 1992
5. Crespi CL, Penman BW, Gelboin HV, et al: A tobacco smoke-derived nitrosamine, 4-(methylnitrosamino)-l-(3-pyridyl)-l-butanone, is activated by multiple human cytochrome P450s including the polymorphic human:ytochrome P4502D6. Carcinogenesis 12:1197-1201, 1991
6. lohansson I, Lundqvist E, Bertilsson L, et al: Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine. Proc Natl Acad Sci U S A 90:11825-11829, 1993
7. Nebert DW: The Ah locus: genetic differences in toxicity, cancer, mutation and birth defects. Crit Rev Toxicol 20:153-174, 1989
8. Uematsu F, Kikuchi H, Motomiya M, et al: Association between restriction fragment length polymorphism of the human cytochrome P450IIE1 gene and susceptibility to lung cancer. Jpn J Cancer Res 82:254-256, 1991
9. Hirvonen A, Husgafvel-Pursiainen K, Anttila S, et al: The human CYP2E1 gene and lung cancer: Dral and Rsal restriction fragment length polymorphisms in a Finnish study population. Carcinogenesis 14:85-88, 1993
10. Kato S, Shields PG, Caporaso NE, et al: Analysis of cytochrome P450 2E1 genetic polymorphisms in relation to human lung cancer. Cancer Epidemiol Biomarkers Prev 3:515-518, 1994
11. Persson I, Johansson I, Bergling H, et al: Genetic polymorphism of cytochrome P4502E1 in a Swedish population. Relationship to incidence of lung cancer. FEBS Lett 319:207-211, 1993
12. Kawajiri K, Nakachi K, Imai K, et al: Identification of genetically high risk individuals to lung cancer by DNA polymorphisms of the cytochrome P450IA1 gene. FEBS Lett 263:131-133, 1990
13. Hayashi S, Watanabe J, Nakachi K, et al: Genetic linkage of lung cancer- associated MspI polymorphisms with amino acid replacement in the heme binding region of the human cytochrome P450IA1 gene. J Biochem (Tokyo) 110:407-411, 1991
14. Hirvonen A, Husgafvel-Pursiainen K, Karjalainen A, et al: Point-mutational Mspl and Ile-Val polymorphisms closely linked in the CYP1A1 gene: lack of association with susceptibility to lung cancer in a Finnish study population. CEBP 1:485-489, 1992
15. Tefre T, Ryberg D, Haugen A, et al: Human CYP1A1 (cytochrome P(1)450) gene: lack of association between the Msp I restriction fragment length polymorphism and incidence of lung cancer in a Norwegian population. Pharmacogenetics 1:20-25, 1991
16. Kawajiri K, Nakachi K, Imai K, et al: The CYP1A1 gene and cancer susceptibility. Crit Rev Oncol Hematol 14:77-87, 1993
17. Seidegard J, Vorachek WR, Pero RW, et al: Hereditary differences in the expression of the human glutathione transferase active on /ram-stilbene oxide are due to a gene deletion. Proc Natl Acad Sci U S A 85:7293-7297, 1988
18. Seidegard J, Pero RW, Markowitz MM, et al: Isoenzyme(s) of glutathione transferase (class Mu) as a marker for the susceptibility to lung cancer: a follow up study. Carcinogenesis 11:33-36, 1990
19. Heckberi SR, Weiss NS, Homung SK, et al: Glutathione 5-transferase and epoxide hydrolase activity in human leukocytes in relation to risk of lung cancer and other smoking-related cancers. J Natl Cancer Inst 84:414-422, 1992
20. Brockmoller J, Kerb R, Drakouiis N, et al: Genotype and phenotype of glutathione S-transferase class mu isoenzymes mu and psi in lung cancer patients and controls. Cancer Res 53:1004-1011, 1993
21. Nazar-Stewart V, Motulsky AG, Eaton DL, et al: The glutathione 5-transferase mu polymorphism as a marker for susceptibility to lung carcinoma. Cancer Res 53:2313-2318, 1993
22. Hirvonen A, Husgafvel-Pursiainen K, Anttila S, et al: The GSTM1 null genotype as a potential risk modifier for squamous cell carcinoma of the lung. Carcinogenesis 14:1479-1481, 1993
23. Zhong S, Howie AF, Ketterer B, et al: Glutathione 5-transferase mu locus: use of genotypirtg and phenotyping assays to assess association with lung cancer susceptibility. Carcinogenesis 12:1533-1537, 1991
24. Nakachi K, Imai K, Hayashi S, et al: Polymorphisms of the CYP1A1 and glutathione S-transferase genes associated with susceptibility to lung cancer in relation to cigarette dose in a Japanese population. Cancer Res 53:2994-2999, 1993
25. Hayashi S, Watanabe J, Kawajiri K: High susceptibility to lung cancer in terms of combined genotypes of P450IA1 and Mu-class glutathione S- transferase genes. Jpn J Cancer Res 83:866-870, 1992
26. van Poppel G, de Vogel N, van Balderen PJ, et al: Increased cytogenetic damage in smokers deficient in glutathione S-transferase isozyme mu. Carcinogenesis 13:303-305, 1992
27. Bartsch H, Petruzzelli S, De Flora S, et al: Carcinogen metabolism and DNA adducts in human lung tissues as affected by tobacco smoking or metabolic phenotype: a case-control study on lung cancer patients. Mutat Res 250:103-114, 1991
28. Shields PG, Bowman ED, Harrington AM, et al: Polycyclic aromatic hydrocarbon-DNA adducts in human lung and cancer susceptibility genes. Cancer Res 53:3486-3492, 1993
29. 32P-postlabeling assay. Carcinogenesis 14:545-550, 1993
30. Langone JJ, Gjika HB, Van Vunakis H: Nicotine and its metabolites. Radioimmunoassays for nicotine and cotinine. Biochemistry 12:50255030, 1973
31. Haley NJ, Axelrad CM, Tilton KA: Validation of self-reported smoking behavior: biochemical analyses of cotinine and thiocyanate. Am J Public Health 73:1204-1207, 1983
32. Heim M, Meyer UA: Genotyping of poor metabolizers of debrisoquine by allele-specific PCR amplification [see comment citation in Medline]. Lancet 336:529-532, 1990
33. Gough AC, Miles JS, Spurr NK, et al: Identification of the primary gene defect at the cytochrome P450 CYP2D locus. Nature 347:773-776, 1990
34. Kato S, Shields PG, Caporaso NE, et al: Cytochrome P450I1E1 genetic polymorphisms, racial variation, and lung cancer risk. Cancer Res 52:6712-6715, 1992
35. Breslow NE, Day NE: Statistical Methods in Cancer Research Volume The Analysis of Case-Control Studies. Lyon: IARC, 1980
36. Phillips DH, Hewer A, Martin CN, et al: Correlation of DNA adduct levels in human lung with cigarette smoking. Nature 336:790-792, 1988
37. Dunn BP, Vedal S, San RH, et al: DNA adducts in bronchial biopsies, Int J Cancer 48:485-492, 1991
38. Cuzick J, Routledge MN, Jenkins D, et al: DNA adducts in different tissues of smokers and non-smokers. Int J Cancer 45:673-678, 1990
39. Uematsu F, Ikawa S, Kikuchi H, et al: Restriction fragment length polymorphism of the human CYP2E1 (cytochrome P450IIE1) gene and susceptibility to lung cancer: possible relevance to low smoking exposure. Pharmacogenetics 4:58-63, 1994
40. Ryberg D, Kure E p53 mutations in lung tumors: relationship to putative susceptibility markers for cancer. Cancer Res 54:15511555, 1994
41. Nakachi K, Imai K, Hayashi S, et al: Genetic susceptibility to squamous cell carcinoma of the lung in relation to cigarette smoking dose. Cancer Res 51:5177-5180, 1991
42. Vineis P, Bartsch H, Caporaso N, et al: Genetically based /V-acctyl- transferase metabolic polymorphism and low-level environmental exposure to carcinogens. Nature 369:154-156, 1994