Binding of coumarins to site I of human serum albumin. Effect of the fatty acids

Chemico-Biological Interactions

Volumn 97, Issue 2, 1995, Pages 169-174

  Zaton A M L ^a   Ferrer, J M ^a   de Gordoa, J C Ruiz ^a   Marquinez M A ^a  

^a UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

Author keywords

3 Acetylcoumarin; 4 Hydroxycoumarin; Chromanol; Coumarin; Fatty acids effect; Site I on seroalbumin; Warfarin

Indexed keywords

4 CHROMANOL; 4 HYDROXYCOUMARIN; COUMARIN DERIVATIVE; FATTY ACID; PHENYLBUTAZONE; UNCLASSIFIED DRUG; WARFARIN;

ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; DRUG PROTEIN BINDING; HUMAN;

BIOLOGICAL TRANSPORT; CHROMANS; COMPARATIVE STUDY; COUMARINS; FATTY ACIDS; HUMAN; LIGANDS; PHENYLBUTAZONE; RECEPTORS, ALBUMIN; SERUM ALBUMIN; SUPPORT, NON-U.S. GOV'T; WARFARIN;

EID: 0029008663     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/0009-2797(95)03613-Q     Document Type: Article

References (11)

1. Comparative pharmacokinetics of coumarin anticoagulants XLV. Pharmacokinetic and pharmacodynamic studies of acute interaction between warfarin and phenylbutazone in rats
2. Binding of coumarin anticoagulants to human and bovine serum albumin
3. Further characterization of specific drug binding sites on human serum albumin
4. Binding of drugs to human serum albumins
5. Characterization of an important drug binding area on human serum albumin including the high-affinity binding sites of warfarin and azapropazone
6. Effect of long-chain free fatty acids on the conformation of the human serum albumin-warfarin binding site as studied by circular dichroism
7. The binding of thioureylene compounds to human serum albumin
8. Properties of graphical representations of multiple classes of binding sites
9. The attractions of proteins for small molecules and ions
10. Atomic structure and chemistry of human serum albumin