Herbimycin A induces the 20 S proteasome- and ubiquitin-dependent degradation of receptor tyrosine kinases

Journal of Biological Chemistry

Volumn 270, Issue 28, 1995, Pages 16580-16587

  Sepp Lorenzino, L ^a   Ma, Z ^a   Lebwohl, D E ^a   Vinitsky, A ^a   Rosen, N ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL RECEPTOR; CYSTEINE PROTEINASE INHIBITOR; DITHIOTHREITOL; ENZYME INHIBITOR; EPIDERMAL GROWTH FACTOR RECEPTOR; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; HERBIMYCIN A; INSULIN RECEPTOR; PROTEASOME; PROTEIN TYROSINE KINASE; SERINE PROTEINASE INHIBITOR; SOMATOMEDIN RECEPTOR; UBIQUITIN;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; ENZYME DEGRADATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; TEMPERATURE SENSITIVE MUTANT;

AMINO ACID SEQUENCE; CYSTEINE ENDOPEPTIDASES; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMAN; MOLECULAR SEQUENCE DATA; MULTIENZYME COMPLEXES; PROTEIN-TYROSINE KINASE; QUINONES; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, IGF TYPE 1; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TUMOR CELLS, CULTURED; UBIQUITINS;

EID: 0029008487     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.270.28.16580     Document Type: Article

References (0)