Protein kinases in human breast cancer

Breast Cancer Research and Treatment

Volumn 35, Issue 1, 1995, Pages 105-114

  Cance, William G ^a   Liu, Edison T ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

breast cancer; focal adhesion kinase; HER 2; novel genes; protein kinases; tyrosine kinases

Indexed keywords

CELL ADHESION MOLECULE; GROWTH FACTOR RECEPTOR; PROTEIN KINASE; PROTEIN TYROSINE KINASE;

ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CELL ADHESION; HUMAN; MALIGNANT TRANSFORMATION; ONCOGENE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN FAMILY; TUMOR GROWTH;

BREAST NEOPLASMS; CELL ADHESION MOLECULES; CELL CYCLE; FEMALE; HUMAN; PROTEIN KINASES; PROTEIN-TYROSINE KINASE; RECEPTOR, ERBB-2; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0029003828     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/BF00694751     Document Type: Article

References (55)

1. Structural organization of the bcr gene and its role in the Ph1 translocation
2. PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas
3. Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer
4. Activated oncogenes and putative tumor suppressor genes involved in human breast cancers
5. Neu protein overexpression in breast cancer. Association with comedotype ductal carcinoma in situ and limited prognostic value in stage II breast cancer
6. High frequency of HER-2/neu amplification in in situ carcinoma of the breast: Analysis using differential polymerase chain reaction
7. c-erbB2 expression in different histologic types of invasive carcinoma
8. Her-2/neu and INT2 proto-oncogene amplification in malignant breast tumors in relation to reproductive factors and exposure to exogenous hormones
9. Insulin-like growth factor receptor expression and function in human breast cancer
10. Prognostic significance of insulin like growth factor I receptors in human breast cancer
11. Towards a molecular basis for tamoxifen resistance in breast cancer
12. The clinical significance of epidermal growth factor receptor in human breast cancer. A review of 5232 patients
13. Overexpression of TGFα in transgenic mice: induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast
14. c-erbB-2 expression and S-phase activity predict response to adjuvant therapy in women with node positive early breast cancer
15. Antitumor effects of doxorubicin in combination with anti-epidermal growth factor receptor monoclonal antibodies
16. p185c-erbB-2 signaling enhances cisplatin-induced cytotoxicity in human breast carcinoma cells: association between an oncogenic receptor tyrosine kinase and drug-induced DNA repair
17. Novel protein kinases expressed in human breast cancer
18. The nucleotide sequence and the tissue-specific expression of Drosophila c- src
19. Novel protein-tyrosine kinase cDNAs related to fps/fes and eph cloned using anti-phosphotyrosine antibody
20. Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction
21. Identification of sequences required for the efficient localization of the focal adhesion kinase, pp125FAK, to cellular focal adhesions
22. Complementation used to clone a human homologue of the fission yeast cell cycle control gene cdc2
23. Mitotic induction and maintenance by overexpression of a G2-specific gene that encodes a potential protein kinase
24. Protein kinase activity associated with the product of the yeast cell division cycle gene CDC28
25. The cell cycle control gene cdc2+ of fission yeast encodes a protein kinase potentially regulated by phosphorylation
26. A yeast gene that is essential for release from glucose repression encodes a protein kinase
27. Mutations of the ras protooncogenes in chronic myelogenous leukemia: a high incidence of ras mutations in bcr/abl rearrangement negative chronic myelogenous leukemia
28. BCR-ABL-induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein
29. Activation of the pp60 src protein kinase is an early event in colonic carcinogenesis
30. c- src activation in human colon carcinoma
31. Tyrosine kinase activity in breast cancer, benign breast, and normal breast tissue
32. Characterization of protein tyrosine kinases from human breast cancer: involvement of the src oncogene product
33. The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and-gamma signal transduction
34. Cytokine signal transduction
35. Involvement of the JAK-3 Janus kinase in signaling by interleukins 2 and 4 in lymphoid and myeloid cells
36. Receptors for interleukin 2 on human squamous cell carcinoma cell lines and tumor in situ
37. Cancer metastasis and angiogenesis: an imbalance of positive and negative regulation
38. Focal adhesion kinase (p125FAK): a point of convergence in the action of neuropeptides, integrins, and oncogenes
39. Adhesion molecules in cancer: the role of integrins
40. Cell adhesion or integrin clustering increases phosphorylation of a focal adhesion-associated tyrosine kinase
41. Expression of Focal Adhesion Kinase gene and invasive cancer
42. Amplification of the int-2 gene in primary human breast tumors
43. Correlation between long-term survival in breast cancer patients and amplification of two putative oncogene-coamplification units: hst-1/int-2 and c-erbB-2/ear-1
44. Amplification of human int-2 in breast cancers and squamous carcinomas
45. D11S287, a putative oncogene on chromosome 11q13, is amplified and expressed in squamous cell and mammary carcinomas and linked to BCL-1
46. Human Dtype cyclin
47. The ins and outs of RB: Coupling gene expression to the cell cycle clock
48. p34cdc2: the S and M kinase?
49. G1 control in yeast and animal cells
50. Cyclin-dependent regulation of G1 in mammalian fibroblasts
51. WAF1, a potential mediator of p53 tumor suppression
52. Two novel human serine/threonine kinases with homologies to the cell cycle regulating Xenopus M015, and NIMA kinases: cloning and characterization of their expression pattern
53. Antisense inhibition of wnt-1 expression in mouse embryos results in hindbrain, cardiac, and facial abnormalities