Polycystic kidney disease: The complete structure of the PKD1 gene and its protein

Cell

Volumn 81, Issue 2, 1995, Pages 289-298

  The International Polycystic Kidney Disease Consortium, ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

LECTIN;

AMINO ACID SEQUENCE; ARTICLE; AUTOSOMAL DOMINANT DISORDER; CHROMOSOME 16; DNA FLANKING REGION; EXON; GENE LOCUS; GENE MUTATION; HUMAN; HUMAN CELL; KIDNEY POLYCYSTIC DISEASE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE;

EID: 0029002967     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/0092-8674(95)90339-9     Document Type: Article

References (68)

1. Protein database searches for multiple alignments
2. Issues in searching molecular sequence databases
3. Number of CpG islands and genes in human and mouse
4. Evolutionary conservation of intron position in a subfamily of genes encoding carbohydrate-recognition domains
5. Extracellular modules
6. From genome sequences to protein function
7. Analysis and nucleotide sequences of the genes encoding the surface-layer glycoproteins of the hyperthermophilic methanogen Methanothermus tervidus and Methanothermus sociabilis
8. Tubular basement membrane changes in 2-amino-4,5-diphenylthiazol induced polycystic kidney disease
9. Polycystic kidney: primary extracellular matrix abnormality or effective cellular differentiation?
10. Injury and development in polycystic kidney disease
11. Tubular basement membrane change occurs pari passu with the development of cyst formation
12. Cell polarity in human renal cystic disease
13. Biology of polycystic kidney disease
14. Evidence for a third genetic locus for autosomal dominant polycystic kidney disease
15. A sequence assembly and editing program for efficient management of large projects
16. Evolutionary mobile modules in proteins
17. Two distinct classes of carbohydrate-recognition domains in animal lectins
18. Expression of clustering in human renal diseases
19. Identification and characterization of the tuberous sclerosis gene on chromosome 16
20. The polycystic kidney disease 1 gene encodes a 14 kb transcript and lies within a duplicated region on chromosome 16
21. Polypoid and papillary hyperplasia: a potential cause of ductal obstruction in adult polycystic kidney disease
22. Icelandic families with autosomal dominant polycystic kidney disease: families unlinked to chromosome 16p13.3 revealed by linkage analysis
23. Autosomal dominant polycystic kidney disease: more than a renal disease
24. The gene for autosomal dominant polycystic kidney disease lies in a 750 kb CpG-rich region
25. Polycystic kidney disease: neoplasia in disguise
26. Profile analysis: detection of distantly related proteins
27. The Toll gene of Drosophila, required for dorsal-ventral embryonic polarity, appears to encode a transmembrane protein
28. Basement membrane gene expression in polycystic kidney disease
29. Performance evaluation of amino acid substitution matrices
30. Saturating the region of the polycystic kidney disease gene with Notl linking clones
31. Erratum
32. Integrins: versatility, modulation, and signals in cell adhesion
33. Autosomal polycystic kidney disease: localization of the second gene to chromosome 4813-q23
34. Co-expression of extracellular matrix glycoproteins undulin and tenascin in human autosomal dominant polycystic kidney disease
35. The leucine-rich repeat a versatile binding motif
36. A structural basis of the interactions between leucine-rich repeats and protein ligands
37. A mutation in the gene for type III procollagen (COL3A1) in a family with aortic aneurysms
38. Yeast chromosome III: new gene functions
39. Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs
40. Structures and functions of multiligand lipoprotein receptors
41. Pigmentation genes the tyrosinase gene family and the pmel 17 gene family
42. Complete sequence and expression of a cDNA encoding a chicken 115 kD melanosomal matrix protein
43. Isolation of a cDNA encoding 5T4 oncofetal trophoblast glycoprotein
44. Chromosome 4 localization of a second gene for autosomal-dominant polycystic kidney disease
45. Multilocus polycystic disease
46. A highly polymorphic DNA marker linked to adult polycystic kidney disease on chromosome 16
47. Morphogenesis of the polarized epithelial cell phenotype
48. A fast, sensitive pattern-matching approach for protein sequences
49. Combining evolutionary information and neural networks to predict protein secondary structure
50. Developing relationships: arterial platelet adhesion, glycoprotein lb, and leucine-rich glycoproteins
51. Slit: an extracellular protein necessary for development of midline glia and commissural axon pathways contains both EGF and LRR domains
52. New perspectives in cell adhesion: RGD and integrins
53. A novel modular mosaic of cell adhesion motifs in the extracellular domains of the neurogeneic trk and trk B tyrosine kinase receptors
54. Linkage disequilibrium in the PKD1 region
55. Fine genetic localization of the gene for autosomal dominant polycystic kidney disease (PKD1) with respect to physically mapped markers
56. The LDL receptor gene: a mosaic of exons shared with different proteins
57. Detection of conserved segments in proteins: iterative scanning of sequence databases with alignment blocks
58. CLUSTALW: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
59. Linkage analysis demonstrates that Marfan syndrome, dominant ectopia lentis and congenital contractural arachnodactyly are linked to the fibrillin genes on chromosomes 15 and 5. N
60. A new method for predicting signal sequence cleavage sites
61. Molecular mechanisms of complex carbohydrate recognition at the cell surface
62. Physical properties of isolated perfused renal tubules and tubular basement membranes
63. nmb, a novel gene, is expressed in low-metastatic human melanoma cell lines and xenografts
64. A new method for studying human polycystic kidney disease epithelia in culture
65. +-ATPase: mislocation to apical plasma membranes in polycystic kidney disease epithelia
66. 2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans
67. An archaeal S-layer gene homolog with repetitive subunits
68. Cloning and nucleotide sequence analysis of the colH gene from Clostridium histolyticum encoding a collagenase and a gelati nase