Cigarette smoke inhibits lung fibroblast proliferation and chemotaxis

American Journal of Respiratory and Critical Care Medicine

Volumn 151, Issue 5, 1995, Pages 1497-1503

  Nakamura, Yoichi ^b   Romberger, Debra J ^b   Tate, Leroy ^b   Ertl, Ronald F ^b   Kawamoto, Masashi ^b   Adachi, Yuichi ^b   Mio, Tadashi ^b   Sisson, Joseph H ^b   Spurzem, John R ^b   Rennard, Stephen I ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ACETALDEHYDE; ACROLEIN; CIGARETTE SMOKE;

ARTICLE; CELL PROLIFERATION; CHEMOTAXIS; CIGARETTE SMOKING; CYTOTOXICITY; FETUS; HUMAN; HUMAN CELL; LUNG EMPHYSEMA; LUNG FIBROBLAST; PRIORITY JOURNAL;

EID: 0029002911     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.151.5.7735606     Document Type: Article

References (29)

1. Higgins, M. W., J. B. Keller, M. Becker, W. Howatt, J. R. Landis, H. Rotman, J. G. Weg, and I. Higgins. 1982. An index of risk for obstructive airways disease. Am. Rev. Respir. Dis. 116:403-410.
2. Higgins, M. 1986. Epidemiology of COPD: state of the art. Chest 85:3-8S.
3. U.S. Department of Health and Human Services. 1984. The Health Consequences of Smoking. A report of the Surgeon General. U.S. Government Printing Office, Washington, DC. Publication No. 84-5025.
4. Smoking and Health: Report of the Advisory Committee to the Surgeon General of the Public Health Service. U.S. Department of Health Education and Welfare, Washington, DC. 14-57.
5. Buist, A. S. 1988. Smoking and other risk factors. In J. F. Murray and J. A. Nadel, editors. Textbook of Respiratory Therapy. WB Saunders, Philadelphia. 1001-1029.
6. Ogushi, F., R. C. Hubbard, C. Vogelmeier, G. A. Fells, and R. G. Crystal. 1991. Risk factors for emphysema. Cigarette smoking is associated with a reduction in the association rate constant of lung alpha-1 antitrypsin for neutrophil elastase. J. Clin. Invest. 87:1060-1065.
7. Auerbach, O., E. C. Hammond, L. Garfinkel, and C. Benante. 1972. Relation of smoking and age to emphysema. Whole-lung section study. N. Engl. J. Med. 286:853-857.
8. Thurlbeck, W. M., J. A. Henderson, R. G. Fraser, and D. V. Bates. 1970. Chronic obstructive lung disease. A comparison between clinical, roentgenologic, functional and morphologic criteria in chronic bronchitis, emphysema, asthma, and bronchiectasis. Medicine. 49:81-145.
9. Janoff, A. 1985. Elastases and emphysema. Current assessment of the protease-antiprotease hypothesis. Am. Rev. Respir. Dis. 132:417-433.
10. Snider, G. L., J. Kleinerman, W. M. Thurlbeck, and Z. H. Bengali. 1985. The definition of emphysema. Report of a National Heart, Lung, and Blood Institute, Division of Lung Diseases Workshop. Am. Rev. Respir. Dis. 132:182-185.
11. Carp, H., and A. Janoff. 1978. Possible mechanisms of emphysema in smokers. In vitro suppression of serum elastase-inhibitory capacity by fresh cigarette smoke and its prevention by antioxidants. Am. Rev. Respir. Dis. 118:617-621.
12. Boyden, S. 1962. The chemotactic effect of mixtures of antibody and antigen on polymorphonuclear leukocytes. J. Exp. Med. 115:453-466.
13. Postlethwaite, A. E., R. Snyderman, and A. H. Kang. 1976. The chemotactic attraction of human fibroblasts to a lymphocyte-derived factor. J. Exp. Med. 144:1188-1203.
14. Falk, W., R. H. Goodwin, and E. J. Leonard. 1980. A 48-well micro chemotaxis assembly for rapid and accurate measurement of leukocyte migration. J. Immunol. Methods 33:239-247.
15. Engvall, E., and E. Ruoslahti. 1977. Binding of soluble form of fibroblast surface protein, fibronectin, to collagen. Int. J. Cancer 20:1-5.
16. Newsome, J. R., V. Norman, and C. H. Keith. 1965. Vapor phase analysis of tobacco smoke. Tobacco Sci. 9:102-110.
17. Gadek, J. E., G. A. Fells, R. L. Zimmerman, S. I. Rennard, and R. G. Crystal. 1981. Antielastases of the human alveolar structures-implications for the protease-antiprotease theory of emphysema. J. Clin. Invest. 68:889-898.
18. Stone, P. J. 1983. The elastase-antielastase hypothesis of the pathogenesis of emphysema. Clin. Chest Med. 4:405-412.
19. Fujita, J., N. L. Nelson, D. M. Daughton, C. A. Dobry, J. R. Spurzem, S. Irino, and S. I. Rennard. 1990. Evaluation of elastase and antielastase balance in patients with bronchitis and pulmonary emphysema. Am. Rev. Respir. Dis. 142:57-62.
20. Snider, G. L., D. E. Ciccolella, S. M. Morris, P. J. Stone, and E. C. Lucey. 1991. Putative role of neutrophil elastase in the pathogenesis of emphysema. Ann. N.Y. Acad. Sci. 624:45-59.
21. Huber, G. L., M. W. First, O. Grubner. 1991. Marijuana and tobacco smoke gas-phase cytotoxins. Pharmacol. Biochem. Behav. 40:629-636.
22. Sisson, J. H., D. J. Tuma, and S. I. Rennard. 1991. Acetaldehyde-mediated cilia dysfunction in bovine bronchial epithelial cells. Am. J. Physiol. 260:L29-L36.
23. Sisson, J. H., and K. L. Leise. 1993. Vapor phase exposure to acetaldehyde generated from ethanol oxidation induces bovine bronchial epithelial cell ciliary slowing. Clin. Res. 41:675A.
24. 2. Am. Rev. Respir. Dis. 145:A827.
25. Dalhamn, T., and A. Rosengren. 1971. Effects of different aldehydes on tracheal mucosa. Arch. Otolaryngol. 93:496-500.
26. Ertl, R. F., V. Valenti, J. R. Spurzem, M. Kawamoto, Y. Nakamua, T. Veys, L. Allegra, D. J. Romberger, and S. I. Rennard. 1992. Prostaglandin E inhibits fibroblast recruitment. Am. Rev. Respir. Dis. 145:A19.
27. 2: a potential regulator of fibroblast replication in the normal alveolar structures. Am. Rev. Respir. Dis. 127:A271.
28. Krokan, H., R. C. Grafstrom, K. Sundqvist, H. Esterbauer, and C. C. Harris. 1985. Cytotoxicity, thiol depletion and inhibition of O-6-methylguanine-DNA methyltransferase by various aldehydes in cultured human bronchial fibroblasts. Carcinogenesis 6:1755-1759.
29. Brock, N. 1976. Comparative pharmacological study in vitro and in vivo with cyclophosphamide (NSC-26271), cyclophosphamide metabolites and plain nitrogen mustard compounds. Cancer Treat. Rep. 60:301-307.