Two distinct and independent sites on IL-6 trigger gp130 dimer formation and signalling

EMBO Journal

Volumn 14, Issue 9, 1995, Pages 1942-1951

  Paonessa, Giacomo ^a   Graziani, Rita ^a   De Serio, Anna ^a   Savino, Rocco ^a   Ciapponi, Laura ^a   Lahm, Armin ^a   Salvati, Anna Laura ^a   Toniatti, Carlo ^a   Ciliberto, Gennaro ^a  

^a IRBM   (Italy)

Author keywords

gp130 dimer; IL 6 receptor antagonist; IL 6 receptor complex; IL 6R

Indexed keywords

CELL SURFACE PROTEIN; INTERLEUKIN 6; INTERLEUKIN RECEPTOR; MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY; RECEPTOR SUBUNIT;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; CONTROLLED STUDY; DIMERIZATION; IMMUNOPRECIPITATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN QUATERNARY STRUCTURE; PROTEIN VARIANT; RECEPTOR BINDING; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION;

EID: 0029002866     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1995.tb07186.x     Document Type: Article

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