The heterogeneous distribution of brain transferrin

Journal of Neuropathology and Experimental Neurology

Volumn 54, Issue 3, 1995, Pages 395-403

  Koeppen, Arnulf H ^a,b   Dickson, Andrew C ^a   McEvoy, Jennifer A ^a  

^a Neurology Service (127)   (United States)

^b ALBANY MEDICAL COLLEGE   (United States)

Author keywords

Bergmann glia; Brain transferring; Carbohydrates; Immunocytochemistry; Lectin affinity; Oligodendroglia; Rabbit; Rat

Indexed keywords

TRANSFERRIN;

ANIMAL TISSUE; ARTICLE; IMMUNOCYTOCHEMISTRY; IRON TRANSPORT; LIGAND BINDING; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; RABBIT; RAT; SPECIES DIFFERENCE; TISSUE DISTRIBUTION;

ANIMAL; BRAIN; BRAIN CHEMISTRY; IMMUNOHISTOCHEMISTRY; IRON; LECTINS; RABBITS; RATS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; TRANSFERRIN;

EID: 0028998326     PISSN: 00223069     EISSN: 15546578     Source Type: Journal    
DOI: 10.1097/00005072-199505000-00012     Document Type: Article

References (58)

1. Bloch B, Popovici T, Levin MJ, Tuil D, Kahn A. Transferrin gene expression visualized in oligodendrocytes of the rat brain by in situ hybridization and immunohistochemistry. Proc Natl Acad Sci USA 1985;82:6706-10
2. Connor JR. Fine RE. The distribution of transferrin immunoreac-tivity in the rat central nervous system. Brain Res 1986;368:319-28
3. Aldred AR, Dickson PW, Marley PD, Schreiber G. Distribution of transferrin synthesis in brain and other tissues in the rat. J Biol Chem 1987;262:5293-7
4. Tsutsumi M, Skinner MK, Sanders-Bush E. Transferrin gene expression and synthesis by cultured choroid plexus epithelial cells. J Biol Chem 1989;264:9626-31
5. Mollgard K, Jacobsen M, Jacobsen GK, Clausen PP, Saunders NR. Immunohistochemical evidence for an intracellular localization of plasma proteins in human foetal choroid plexus and brain. Neurosci Lett 1979;14:85-90
6. Toran-Allerand CD. Coexistence of a-fetoprotein, albumin, and transferrin immunoreactivity in neurones of the developing mouse brain. Nature 1980;286:733-5
7. Cavanagh ME, Mollgard K. An immunocytochemical study of the distribution of some plasma proteins within the developing fore-brain of the pig with special reference to the neocortex. Dev Brain Res 1985;17:193-4
8. Oh TH, Markelonis GJ, Royal GM, Bregnan BS. Immunocytochemical distribution of transferrin and its receptor in the developing chicken nervous system. Dev Brain Res 1986;30:207-20
9. M0llgard K, Dziegielewska KM, Saunders NR, Zakut H, Soreq H. Synthesis and localization of plasma proteins in the developing human brain. Dev Biol 1988;128:207-21
10. Espinosa de los Montcros A, Chiapelli F, Fisher RS, de Vcllis J. Transferrin.: An early marker of oligodendrocytes in cultures. Int J Dev Neurosci 1988;6:167-75
11. Connor JR, Phillips TM, Laksman MR, Barron KD, Fine RE, Csiza CK. Regional variation in the levels of transferrin in the CNS of normal and myelin-deficient rats. J Neurochem 1987;49:1523-9
12. Koeppen AH, Barron KD, Csiza CK, Greenfield EA. Comparative immunoc'ytochemistry of Pelizaeus-Merzbacher disease, the jimpy mouse, and the myelin-deficient rat. J Neurol Sci 1988;84:315-27
13. Bartlett WP, Li X-S, Connor JR. Expression of transferrin mRNA in the CNS of normal and jimpy mice. J Neurochem 1993;57: 318-23
14. Connor JR, Roskams AJ, Menzies SL, Williams ME. Transferrin in the central nervous system of the shiverer mouse myelin mutant. J Neurosci Res 1993;36:501-7
15. Angelova-Gateva P. Iron transferrin receptors and human cerebrum. Agressologie 1980;21:27-30
16. Jefferies WA, Brandon MR, Hunt SV, Williams AF, Gatter KC, Mason DY. Transferrin receptors on endothelium of brain capillaries. Nature 1984;312:162-3
17. Hill JM, Ruff MR, Weber RJ, Pert CB. Transferrin receptors in rat brain: Neuropeptide-like pattern and relationship to iron distribution. Proc Natl Acad Sci USA 1985;82:4553-7
18. Lin HH, Connor JR. The development of the transferrin receptor system in relation to astrocytes, MBP, and galactocerebrosides in normal and myelin-deficient rat optic nerves. Dev Brain Res 1989;49:281-93
19. Koeppen AH, Dickson AC, Chu RC, Thach RE. The pathogenesis of superficial siderosis of the central nervous system. Ann Neurol 1993;34:646-53
20. Giometto B, Bozza F, Argentiero V, Gallo P, Pagni S, Picinno MG, Tavalato B. Transferrin receptor in rat central nervous system. An immunocytochemical study. J Neurol Sci 1990;98:81-90
21. Fishman JB, Rubin JB, Handrahan JV, Connor JR, Fine RE. Receptor mediated transcytosis of transferrin across the blood-brain barrier. J Neurosci Res 1987;18:299-304
22. Banks WA, Kastin AJ, Fasold MB, Barrera CM, Angereau G. Studies of the slow, bidirectional transport of iron and transferrin across the blood-brain barrier. Brain Res 1988;21:881-5
23. Taylor EM, Crowe A, Morgan EH. Transferrin and iron uptake by the brain: Effects of altered iron status. J Neurochem 1991;57: 1584-92
24. Ueda F, Raja KB, Simpson RJ, Trowbridge IS, Bradbury MWB. Rate of 59Fe uptake into brain and cerebrospinal fluid and the influence thereon of antibodies against the transferrin receptor. J Neurochem 1993;60:106-13
25. Dallman PR, Siimes MA, Manies EC. Brain iron: Persistent deficiency following short-term iron deprivation in the young rat. Br J Haematol 1975;31:209-15
26. Hill JM. The distribution of iron in the brain. In: Youdim MBH, ed. Brain iron: Neurochemical and behavioral aspects. New York: Taylor and Francis, 1988:1-24
27. Dwork AJ, Schon EA, Herbert J. Nonidentical distribution of transferrin and ferric iron in human brain. Neuroscience 1988;27:333-45
28. Espinosa de los Monteros A, Pena LA, de Vellis J. Does transferrin have a special role in the nervous system? J Neurosci Res 1989;24: 125-36
29. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding. Anal Biochem 1976;72:248-54
30. Tarentino AL, Gomez CM, Plummer TH. Deglycosylation of as-paragine-linked glycans by peptide: N-glycosidase F. Biochemistry 1985;24:4665-71
31. Laemmli UK. Cleavage of structural proteins during the assembly of bacteriophage T4. Nature 1970;227:680-5
32. Towbin H, Staehelin T, Gordon J. Electophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications. Proc Natl Acad Sci USA 1979;76:4350-4
33. Hsu S-M, Raine L, Fanger H. Use of avidin-biotin peroxidase complex (ABC) in immunoperoxidase techniques: A comparison between ABC and unlabeled antibody (PAP) procedures. J Histochem Cytochem 1981;29:577-80
34. Livingston DM. Immunoafrinity chromatography of proteins. In: Jakoby WB, Wilchek M, eds. Methods in enzymology. Vol 134. New York: Academic Press, 1974:723-31
35. Koeppen AH, Borke RC. Experimental superficial siderosis of the central nervous system. I. Morphological observations. J Neuro-pathol Exp Neurol 1991;50:579-94
36. Hill JM, Switzer RC. The regional distribution and cellular localization of iron in the rat brain. Neuroscience 1984; 11:595-603
37. Koeppen AH, Mitzen EJ, Hans MB, Barron KD. Olivopontocerebellar atrophy. Immunocytochemical and Golgi observations. Neurology 1986;36:1478-88
38. Koeppen AH, Hurwitz CG, Dearborn RE, Dickson AC, Borke RC, Chu RC. Experimental superficial siderosis of the central nervous system. Biochemical correlates. J Neurol Sci 1992;112:38-45
39. Kornfeld K, Reitman ML, Kornfeld R. The carbohydrate-binding specificity of pea and lentil lectins. J Biol Chem 1981;256:6633-40
40. Shibuya N, Goldstein IJ, van Damme EJM, Peumans WJ. Binding properties of a mannose-specific lectin from snow drop (Galanthus nivalis) bulb. J Biol Chem 1988;263:728-34
41. Shibuya N, Goldstein IJ, Broekaert WF, Nsimba-Lubaki M, Peeters B, Peumans WJ. The elderberry (Sambucus nigra L) bark lectin recognizes the Neu5Ac(a2-6)gal/galNAc sequence. J Biol Chem 1987;262:1596-1601
42. Wang W-C, Cummings RD. The immobilized leukoagglutinin from the seeds of Maackia amurensis binds with high affinity to complex-type Asn-linked oligosaccharides containing terminal sialic acid linked α-2,3 to penultimate galactose residues. J Biol Chem 1988;263:4576-85
43. Yamashita K, Totani K, Ohkura T, Takasaki S, Goldstein IJ, Kobata A. Carbohydrate binding properties of complex-type oligosaccharides on immobilized Datura stramonium lectin. J Biol Chem 1987;262:1602-7
44. Lotan R, Skutelsky E, Danon D, Sharon N. The purification, composition, and specificity of the anti-T lectin from peanut (Arachis hypogea). J Biol Chem 1975;250:8518-23
45. Benkovic SA, Connor JR. Ferritin, transferrin, and iron in selected regions of the adult and aged rat brain. J Comp Neurol 1993;338: 97-113
46. Spik G, Coddeville B, Strecker G, Montreuil J, Regoeczi E, Chin-demi PA, Rudolph JR. Carbohydrate microheterogeneity of rat sero-transferrin. Eur J Biochem 1991;195:397-405
47. Regoeczi E, Chindemi PA, Rudolph JR, Spik G, Montreuil J. The chromatographic heterogeneity of rat transferrin on immobilized concanavalin A and lentil lectin. Biochem Cell Biol 1987;65: 948-54
48. Supler ML, Semple-Rowland SL, Streit W. Oligodendrocytes produce low molecular weight glycoproteins containing N-acetyl-D-glucosamine in their Golgi apparatus. Glia 1994;10:193-201
49. Hayashi A, Wada Y, Suzuki T, Shimizu A. Studies on familial hy-potransferrinemia: Unique clinical course and molecular pathology. Am J Hum Genet 1993;53:201-13
50. Heilmeyer L, Keller W, Vivell O, Keiderling W, Betke K, Wöhler F, Schultze HE. Kongenitale Atransferrin'amie bei einem sieben Jah-re alien Kind. Deutsch Med Wchnschr 1961;86:1745-51
51. Walbaum R. Deficit congenital en transferrine. Lille Mecl 1971; 16: 1172-4
52. Dickinson TK, Connor JR. Histological analysis of selected brain regions of hypotransferrinemic mice. Brain Res 1994;635:169-78
53. Mason AB, Miller MK, Funk WD, et al. Expression of glycosylated and nonglycosylated proteins with comparison to three commercially available transferrins. Biochemistry 1993;32:5472-9
54. Kristiansson B, Andersson M, Tonnby B, Hagberg B. Disialotrans-ferrin developmental deficiency syndrome. Arch Dis Child 1989;64: 71-6
55. Stibler H, Jaeken J. Carbohydrate deficient serum transferrin in a new systemic hereditary syndrome. Arch Dis Child 1990;65: 107-11
56. Horslen SP, Clayton PT, Harding BN, Hall NA, Keir G, Winchester B. Olivopontocerebellar atrophy of neonatal onset and disialotrans-ferrin developmental deficiency syndrome. Arch Dis Child 1991;66: 1027-32
57. Blennow G, Jaeken J, Wiklund LM. Neurological findings in the carbohydrate-deficient glycoprotein syndrome. Acta Paediat Scand 1991;Suppl 375:14-20
58. Stibler H. Carbohydrate-deficient transferrin in serum: A new marker of potentially harmful alcohol consumption reviewed. Clin Chem 1991;37:2029-37