Role of clostridium difficile in childhood diarrhea

Pediatric Infectious Disease Journal

Volumn 14, Issue 7, 1995, Pages 598-603

  Cerquetti, Marina ^a   Luzzi, Ida ^a   Caprioli, Alfredo ^a   Sebastianelli, Annalisa ^a   Mastrantonio, Paola ^a  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

Author keywords

Childhood diarrhea; Clostridium difficile; Electrophoretic typing

Indexed keywords

CLOSTRIDIUM DIFFICILE TOXIN B;

ACUTE DIARRHEA; ARTICLE; BACTERIUM ISOLATION; CHILD; CHILDHOOD DISEASE; CLOSTRIDIUM DIFFICILE; CONTROLLED STUDY; FECES ANALYSIS; FECES CULTURE; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PSEUDOMEMBRANOUS COLITIS;

BACTERIAL TOXINS; CHILD; CHILD, PRESCHOOL; CLOSTRIDIUM DIFFICILE; DIARRHEA; ELECTROPHORESIS, AGAR GEL; ENTEROCOLITIS, PSEUDOMEMBRANOUS; FECES; FEMALE; HUMAN; IMMUNOBLOTTING; INFANT; MALE; SUPPORT, NON-U.S. GOV'T;

EID: 0028998235     PISSN: 08913668     EISSN: 15320987     Source Type: Journal    
DOI: 10.1097/00006454-199507000-00009     Document Type: Article

References (38)

1. Bartlett JG. Clostridium difficile', clinical considerations. Rev Infect Dis 1990;12(Suppl 2):43-51.
2. George RH. The carrier state: Clostridium difficile. J Antimi- crob Chemother 1986;18(Suppl A):47-58.
3. Cerquetti M, Pantosti A, Grieco L, Mastrantonio P. Clostridium difficile in healthy adults: evaluation of carriage using an enrichment medium. Microbiol Ecol Health Dis 1989;2: 215-8.
4. Tullus K, Aronsson B, Marcus S, Mollby R. Intestinal colonization with Clostridium difficile in infants up to 18 months of age. Eur J Clin Microbiol Infect Dis 1989;8:390-3.
5. Lyerly DM, Saum KE, MacDonald DK, Wilkins TD. Effects of Clostridium difficile toxins given intragastrically to animals. Infect Immun 1985;47:349-52.
6. Emeruwa AC, Oguike JU. Incidence of cytotoxin producing isolates of Clostridium difficile in faeces of neonates and children in Nigeria. Microbiologica 1990;13:323-8.
7. Yamamoto-Osaki TY, Kamiya S, Sawamura S, Kai M, Osawa A. Growth inhibition of Clostridium difficile by intestinal flora of infant faeces in continuous flow culture. J Med Microbiol 1994;40:179-87.
8. Viscidi R, Willey S, Bartlett JG. Isolation rates and toxigenic potential of Clostridium difficile isolates from various patient populations. Gastroenterology 1981;81:5-9.
9. Rietra PJGM, Slaterus KW, Zanen HC, Meuwissen SGM. Clostridia] toxin in faeces of healthy infants. Lancet 1978;2: 319.
10. Collignon A, Ticchi L, Depitre C, Gaudelus J, Delmèe M., Corthier G. Heterogeneity of Clostridium difficile isolates from infants. Eur J Pediatr 1993;152:319-22.
11. Delmèe M, Bulliard G, Simon G. Application of a technique for serogrouping Clostridium difficile in an outbreak of anti- biotic-associated diarrhoea. J Infect 1986;13:5-9.
12. McFarland LV, Mulligan ME, Kwok RYY, Stamm WE. Nosocomial acquisition of Clostridium difficile infection. N Engl J Med 1989;320:204-10.
13. McKay I, Coia JE, Poxton IR. Typing of Clostridium difficile causing diarrhoea in an orthopaedic ward. J Clin Pathol 1989;42:511-5.
14. Kristjànsson M, Samore MH, Gerding DN, et al. Comparison of restriction endonuclease analysis, ribotyping.and pulsed- field gel electrophoresis for molecular differentiation of Clostridium difficile strains. J Clin Microbiol 1994;32:1963-9.
15. Pantosti A, Cerquetti M, Mastrantonio Gianfrilli P. Electrophoretic characterization of Clostridium difficile strains isolated from antibiotic-associated colitis and other conditions. J Clin Microbiol 1988;26:540-3.
16. Ewing WH. Identification of enterobacteriaceae. New York: Elsevier, 1986.
17. Garcia LS, Bruckener DA, Brewer TC, Shimizu RY. Techniques for the recovery and identification of Cryptosporidium oocyst from stool specimens. J Clin Microbiol 1983;18:185-90.
18. Carroll SM, Bowman RA, Riley TV. A selective broth for Clostridium difficile. Pathology 1983;15:165-7.
19. George WL, Sutter VL, Citron D, Finegold SM. Selective and differential medium for isolation of Clostridium difficile. Clin Microbiol 1979;9:214-9.
20. De Girolami PC, Hanff PA, Eichelberger K, et al. Multicenter evaluation of a new enzyme immunoassay for detection of Clostridium difficile enterotoxin A. J Clin Microbiol 1992;30:1085-8.
21. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem 1951;193:265-75.
22. Laemmli UK Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970;227:680-5.
23. Cerquetti M, Pantosti A, Stefanelli P, Mastrantonio P. Purification and characterization of an immunodominant 36 kDa antigen present on the cell surface of Clostridium difficile. Microb Pathog 1992;13:271-9.
24. Cardines R, Luzzi I, Menichella G, Virgili A, Mastrantonio P. Clostridium difficile in preterm neonates. Microbiologica 1988;11:259-61.
25. el-Mohandes AE, Keiser JF, Refat M, Jackson BJ. Prevalence and toxigenicity of Clostridium difficile isolates in fecal microflora of preterm infants in the intensive care nursery. Biol Neonate 1993;63:225-9.
26. Bacon AE, Fekety R, Schaberg DR, Faix RG. Epidemiology of Clostridium difficile colonization in newborns: results using a bacteriophage and bacteriocin typing system. J Infect Dis 1988;158:349-54.
27. Holton AF, Hall MA, Lowes JA. Antibiotic exposure delays intestinal colonization by Clostridium difficile in the newborn. J Antimicrob Chemother 1989;24:811-7.
28. Camorlinga M, Munoz O, Guiscafre H, Torres J. Colonization by Clostridium difficile in hospitalized children: risk factors and typification of the isolated strains. Arch Invest Med 1991;22:19-26.
29. Kato H, Kato N, Watenabe K, et al. Application of typing by pulse-field gel electrophoresis to the study of Clostridium difficile in a neonatal intensive care unit. J Clin Microbiol 1994;32:2067-70.
30. Kiru K, DuPont HL, Pickering LK. Outbreaks of diarrhea associated with Clostridium difficile and its toxin in day-care centers: evidence of person-to-person spread. J Pediatr 1983;102:376-82.
31. Ellis ME, Mondai BK, Dunbar EM, Bundeil KR. Clostridium difficile and its cytotoxin in infants admitted to hospital with infectious gastroenteritis. Br Med J 1984;288:524-6.
32. Luzzi I, Caprioli A, Falbo V, et al. Detection of clostridial toxins in stools from children with diarrhea. J Med Microbiol 1986;22:29-31.
33. Karsch W, Strelan E, Grahlow WD, Fischer E, Schulz R. Occurrence and significance of Clostridium difficile in fecal specimens of hospitalized children. Zentralbl Bakterial Mik- robiol Hyg 1989;270:441-8.
34. Niyogi SK, Dutta P, Dutta D, Mitra V, Sikdar S. Clostridium difficile and its cytotoxin in hospitalized children with acute diarrhea. Indian Pediatr 1991;28:1129-32.
35. Kelly CP, Pothoulakis C, LaMont JT. Clostridium difficile colitis. N Engl J Med 1994;380:256-61.
36. Knudsen JD, Tvede M. Demonstration of toxin A and B by polymerase chain reaction and McCoy cell assay in clinical isolates of Clostridium difficile from Denmark. APMIS 1993; 101:18-22.
37. Depitre C, Delmee M, Avesani V, et al. Serogroup F strains of Clostridium difficile produce toxin B but not toxin A. J Med Microbiol 1993;38:434-41.
38. Costas M, Holmes B, On SLW, Ganner M, Kelly MC, Nath SK. Investigation of an outbreak of Clostridium difficile infection in a general hospital by numerical analysis of protein patterns by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. J Clin Microbiol 1994;32:759-65.