Of ITAMs and ITIMs: Turning on and off the B cell antigen receptor

Journal of Experimental Medicine

Volumn 181, Issue 6, 1995, Pages 1953-1956

  Thomas, Matthew L ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD22 ANTIGEN; CD5 ANTIGEN; LYMPHOCYTE ANTIGEN RECEPTOR; PROTEIN TYROSINE KINASE;

ANIMAL CELL; ANTIGEN PRESENTATION; ANTIGEN RECOGNITION; ANTIGEN SPECIFICITY; B LYMPHOCYTE ACTIVATION; DEPHOSPHORYLATION; ENZYME ACTIVATION; MOUSE; NONHUMAN; NOTE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMAL; B-LYMPHOCYTES; BINDING SITES; CONSENSUS SEQUENCE; HOMEOSTASIS; HUMAN; MICE; MICE, MUTANT STRAINS; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PHOSPHOTYROSINE; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; TYROSINE;

EID: 0028997875     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.181.6.1953     Document Type: Article

References (34)

1. Weiss, A., and D.R. Littman. 1994. Signal transduction by lymphocyte antigen receptors. Cell 76: 263-274.
2. Cambier, J.C., C.M. Pleiman, and M.R. Clark. 1994. Signal transduction by the B cell antigen receptor and its coreceptors. Amu. Rev. Immunol 12: 457-486.
3. Gold, M.R., and A.L. DeFranco. 1994. Biochemistry of B lymphocyte activation. Adv. Immunol. 55: 221-295.
4. Doody, G.M., L.B. Justement, C.C. Delibrias, R.J. Matthews, J. Lin, M.L. Thomas, and D.T. Fearon. 1995. Restriction of B lymphocyte activation by CD22 and the protein tyrosine phosphatase SHP. Science (Wash. DC). In press.
5. Cyster, J.G., and C.C. Goodnow. 1995. Protein tyrosine phosphatase 1C negatively regulates antigen receptor signaling in B lymphocytes and determines thresholds for negative selection. Immunity. 2: 13-24.
6. D’Ambrosio, D., K.H. Hippen, S.A. Minskoff, I. Mellman, K. A. Siminovitch, G. Pani, and J.C. Cambier. 1995. PTP1C recruitment and activation by FcγRIIBl: a molecular basis for negative signal cooperativity with the B cell antigen receptor. Science (Wish. DC). In press.
7. Pani, G., M. Kozlowski, J.C. Cambier, G.B. Mills, and K.A. Siminovitch. 1995. Identification of the tyrosine phosphatase PTP1C as a B cell antigen receptor-associated protein involved in the regulation of B cell signalling. J. Exp. Med. 181:XXX-XXX.
8. Shultz, L.D., P.A. Schweitzer, T.V. Rajan, T. Yi, J.N. Ihle, R.J. Matthews, M.L. Thomas, and D.R. Beier. 1993. Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene. Cell 73: 1445-1454.
9. Tsui, H.W., K.A. Siminovitch, L. de Souza, and F.W.L. Tsui. 1993. Motheaten and viable motheaten mice have mutations in the haematopoietic cell phosphatase gene. Nature Genet. 4: 124-129.
10. Feng, G.-S., C.-C. Hui, andT. Pawson. 1993. SH2-containing phosphotyrosine phosphatase as a target of protein-tyrosine kinases. Science (Wash. DC). 259: 1607-1611.
11. Vogel, W., R. Lammers, J. Juang, and A. Ullrich. 1993. Activation of a phosphotyrosine phosphatase by tyrosine phosphorylation. Science (Wash. DC). 259: 1611-1614.
12. Zhao, Z., P, Bouchard, C.D. Diltz, S.-H. Shen, and E.H. Fischer. 1993. Purification and characterization of a protein tyrosine phosphatase containing SH2 domains. J. Biol. Chem. 268: 2816-2820.
13. Adachi, M., M. Sekiya, T. Miyachi, K. Matsuno, Y. Hinoda, K. Imai, and A. Yachi. 1992. Molecular cloning of a novel protein-tyrosine phosphatase SH-PTP3 with sequence similarity to the src-homology region 2. FEBS (Fed. Eur. Biochem. Soc.) Lett. 314: 335-339.
14. Freeman, Jr., R.M., J. Plutzky, and B.G. Neel. 1992. Identification of a human src homology 2-containing protein-tyrosine-phosphatase: a putative homolog of Drosophila corkscrew. Proc. Natl. Acad. Sci. USA. 89: 11239-11243.
15. Matthews, R.J., D.B. Bowne, E. Flores, and M.L. Thomas. 1992. Characterization of hematopoietic intracellular protein tyrosine phosphatases: description of a phosphatase containing an SH2 domain and another enriched in proline-, glutamic acid-, serine-, and threonine-rich sequences. Mol Cell Biol. 12: 2396-2405.
16. Perkins, L.A., I. Larsen, and N. Perrimon. 1992. corkscrew encodes a putative protein tyrosine phosphatase that functions to transduce the terminal signal from the receptor tyrosine kinase torso. Cell. 70: 225-236.
17. Plutzky, J., B.G. Neel, and R.D. Rosenberg. 1992. Isolation of a src homology 2-containing tyrosine phosphatase. Proc Natl. Acad. Sci. USA. 89: 1123-1127.
18. Yi, T., J.L. Cleveland, and J.N. Ihle. 1992. Protein tyrosine phosphatase containing SH2 domains: characterization, preferential expression in hematopoietic cells, and localization to human chromosome 12pl2-pl3. Mol Cell Biol. 12: 836-846.
19. Shen, S.-H., L. Bastien, B.I. Posner, and P. Chrétien. 1991. A protein-tyrosine phosphatase with sequence similarity to the SH2 domain of the protein-tyrosine kinases. Nature (Lond.). 352: 736-739.
20. Shultz, L.D. 1991. Hematopoiesis and models of immunodeficiency. Semin. Immunol. 3: 397-408.
21. Amigorena, S., C. Bonnerot, J.R. Drake, D. Choquet, W. Hunziker, J.-G. Guillet, P. Webster, C. Sautes, I. Mellman, and W.H. Fridman. 1992. Cytoplasmic domain heterogeneity and functions of IgG Fc receptors in B lymphocytes. Science (Wash. DC). 256: 1808-1812.
22. Muta, T., T. Kurosaki, Z. Misulovin, M. Sanchez, M.C. Nussenzweig, and J.V. Ravetch. 1994. A 13-amino-acid motif in the cytoplasmic domain of FcγRllB modulates B-cell receptor signalling. Nature (Land.). 368: 70-73.
23. Leprince, C., K.E. Draves, R.L. Geahlen, J.A. Ledbetter, and E.A. Clark. 1993. CD22 asssociates with the human surface IgM-B-cell antigen receptor complex. Proc Natl. Acad. Sci. USA. 90: 3236-3240.
24. Peaker, C.J.G., and M.S. Neuberger. 1993. Association of CD22 with the B cell antigen receptor. Eur. J. Immunol. 23: 1358-1363.
25. Munro, S., B.J.E.G. Bast, K.J. Colley, and T.F. Tedder. 1992. The B lymphocyte surface antigen CD75 is not an a-2,6-sialytransferase but is a carbohydrate antigen, the production of which requires the enzyme. Cell. 68:1003.
26. Pezzutto, A., B. Dorken, G. Moldenhauer, and E.A. Clark. 1987. Amplification of human B cell activation by a monoclonal antibody to the B cell-specific antigen CD22, Bp 130/ 140. J. Immunol. 138: 98-103.
27. Pezzutto, A., P.S. Rabinovitch, B. Dorken, G. Moldenhauer, and E.A. Clark. 1988. Role of the CD22 human B cell antigen in B cell triggering by anti-immunoglobulin. J. Immunol. 140: 1791-1795.
28. Pei, D., B.G. Neel, and C.T. Walsh. 1993. Overexpression, purification, and characterization of SHPTP1, Src homology 2-containing protein-tyrosine-phosphatase. Proc Natl. Acad. Sci. USA. 90: 1092-1096.
29. Townley, R., S.-H. Shen, D. Banville, and C. Ramachandran. 1993. Inhibition of the activity of protein tyrosine phosphatase 1C by its SH2 domains. Biochemistry. 32: 13414-13418.
30. Pei, D., U. Lorenz, U. Klingmuller, EG. Neel, and C.T. Walsh. 1994. Intramolecular regulation of protein tyrosine SH-PTP1: a new function for Src homology domains. Biochemistry. 33: 15483-15493.
31. Sugimoto, S., T.J. Wandless, S.E. Shoelson, B.G. Neel, and C.T. Walsh. 1994. Activation of the SH2-containing protein tyrosine phosphatase, SH-PTP2, by phosphotyrosine-containing peptides derived from insulin receptor substrate-1. J. Biol. Chem. 269: 13614-13622.
32. Yi, T., and J.N. Ihle. 1993. Association of hematopoietic cell phosphatase with c-Kit after stimulation with c-Kit ligand. Mol. Cell. Biol. 13: 3350-3358.
33. Yi, T., A.L.-F. Mui, G. Krystal, and J.N. Ihle. 1993. Hematopoietic cell phosphatase associates with the interleukin-3 (IL3) receptor (3 chain and down-regulates IL-3 induced tyrosine phosphorylation and mitogenesis. Mol. Cell. Biol. 13: 7577-7586.
34. Yi, T., J. Zhang, O. Miura, and J. Ihle. 1995. Hematopoietic cell phosphatase associates with erythropoietin (Epo) receptor after epo-induced receptor tyrosine phosphorylation: identification of potential binding sites. Blood. 85: 87-95.