Chlorzoxazone is metabolized by human CYP1A2 as well as by human CYP2E1

Pharmacogenetics

Volumn 5, Issue 3, 1995, Pages 143-150

  Ono, Satoshi ^a,b   Hatanaka, Toshihiko ^a   Hotta, Hiroshi ^a   Tsutsui, Michio ^a   Satoh, Tetsuo ^b   Gonzalez, Frank J ^c  

^a Central Laboratory   (Japan)

^b CHIBA UNIVERSITY   (Japan)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Aniline; Chlorzoxazone; Cytochrome P450; Metabolism

Indexed keywords

6 HYDROXYCHLORZOXAZONE; ALPHA NAPHTHOFLAVONE; ANILINE; BENZYLOXYRESORUFIN; BUFURALOL; CHLORZOXAZONE; COMPLEMENTARY DNA; COUMARIN; CYTOCHROME P450 ISOENZYME; DIETHYLDITHIOCARBAMIC ACID; DRUG METABOLITE; ENZYME INHIBITOR; ETHOXYRESORUFIN; MUSCLE RELAXANT AGENT; TESTOSTERONE; TOLBUTAMIDE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG HYDROXYLATION; DRUG METABOLISM; ENZYME KINETICS; ENZYME SPECIFICITY; GENE EXPRESSION; HEP 2 CELL; HUMAN; HUMAN CELL; LIVER MICROSOME METABOLISM; PRIORITY JOURNAL; VACCINIA VIRUS;

BENZOFLAVONES; CHLORZOXAZONE; CYTOCHROME P-450 CYP1A2; CYTOCHROME P-450 CYP2E1; CYTOCHROME P-450 ENZYME SYSTEM; DITIOCARB; HUMAN; HYDROXYLATION; MICROSOMES, LIVER; OXIDOREDUCTASES; OXIDOREDUCTASES, N-DEMETHYLATING; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY;

VACCINIA; VACCINIA VIRUS;

EID: 0028997743     PISSN: 0960314X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008571-199506000-00002     Document Type: Article

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