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Volumn 268, Issue 5211, 1995, Pages 731-734

Translational suppression by trinucleotide repeat expansion at FMR1

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; MESSENGER RNA; REPETITIVE DNA; TRINUCLEOTIDE;

EID: 0028989063     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.7732383     Document Type: Article
Times cited : (265)

References (44)
  • 39
    • 0027480960 scopus 로고
    • (1993) Cell , vol.72 , pp. 971
  • 43
    • 0028169728 scopus 로고
    • Cytoplasmic extract was prepared and fractionated on 17.1 to 51 % linear sucrose gradient as described by except that a 2 M sucrose cushion was included at the bottom of the gradient. A total of 21 fractions containing 0.5 to 0.6 ml of the linear gradient were collected from bottom to top starting at the interface. Each fraction was subject to proteinase K digestion followed byphenol-chloroform extraction in order to isolate the total RNA. The ethanol-precipitated RNA in each fraction was subjected to RNase protection analysis (16)
    • (1994) J. Biol. Chem. , vol.269 , pp. 4367
    • Jefferies, H.B.J.1    Thomas, G.2    Thomas, G.3
  • 44
    • 0020652713 scopus 로고
    • 32P-uridine 5′-triphosphate. This riboprobe was used together with the antisense FMR1 riboprobe in each hybridization, and the protected 358-bp HPRT fragment served as an internal control to represent the distribution of actively translated mRNA on the sucrose gradient
    • (1983) Proc. Natl. Acad. Sci. , vol.80 , pp. 477
    • Jolly, D.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.