Interferon-γ inhibits apoptosis induced by wild-type p53, cytotoxic anti-cancer agents and viability factor deprivation in myeloid cells

Leukemia

Volumn 9, Issue 4, 1995, Pages 685-692

  Lotem, J ^a   Sachs, L ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Anti cancer agents; Apoptosis; bcl 2; Interferon ; WAF 1; Wild type p53

Indexed keywords

ANTINEOPLASTIC AGENT; COLONY STIMULATING FACTOR; CYCLIN DEPENDENT KINASE; CYTOKINE; CYTOTOXIC AGENT; GAMMA INTERFERON; INTERLEUKIN 3; INTERLEUKIN DERIVATIVE; PROTEIN P53;

APOPTOSIS; ARTICLE; BONE MARROW CELL; CELL DEATH; CELL DIVISION; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; MYELOID LEUKEMIA; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

EID: 0028987730     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (43)

1. Sachs L. Normal developmental programmes in myeloid leukemia. Regulatory proteins in the control of growth and differentiation. Cancer Surv 1982; 1: 321-342.
2. Sachs L. The molecular control of blood cell development. Science 1987; 238: 1374-1379.
3. Sachs L. The control of growth and differentiation in normal and leukemic blood cells. The 1989 Alfred P. Sloan Prize of the General Motors Cancer Research Foundation. Cancer 1990; 65; 2196-2206.
4. Sachs L, Lotem J. Control of programmed cell death in normal and leukemic cells. New implications for therapy. Blood 1993; 82: 15-21.
5. Sachs L, Lotem J. Apoptosis in the haemopoietic system. In: Gregory CD (ed). Apoptosis and the Immune System. John Wiley and Sons: New York, 1995, pp 371-403.
6. Williams GT et al. Haemopoietic colony-stimulating factors promote cell survival by suppressing apoptosis. Nature 1990; 343: 76-79.
7. Ihle J, Askew D. Origin and properties of hematopoietic growth-factor dependent cell lines, Int J Cell Cloning 1989; 7: 68-91.
8. Fibach E, Sachs L. Control of normal differentiation of myeloid leukemic cells. Xl. Induction of a specific requirement for cell viability and growth during differentiation of myeloid leukemic cells. J Cell Physiol 1976; 89: 259-266.
9. Lotem J, Sachs L. Mechanisms that uncouple growth and differentiation in myeloid leukemia cells. Restoration of requirement for normal growth inducing protein without restoring induction of differentiation inducing protein. Proc Natl Acad Sci USA 1982; 79: 4347-4351.
10. Lotem J, Cragoe EJ Jr, Sachs L. Rescue from programmed cell death in leukemic and normal myeloid cells. Blood 1991; 78: 953-960.
11. Lotem J, Sachs L. Hematopoietic cytokines inhibit apoptosis induced by transforming growth factor β1 and cancer chemotherapy compounds in myeloid leukemic cells. Blood 1992; 80: 1750-1757.
12. Yonish-Rouach E et al. Wild-type p53 induces apoptosis of myeloid leukemic cells that is inhibited by interleukin 6. Nature 1991; 352: 345-347.
13. Lotem J, Sachs L. Hematopoietic cells from mice deficient in wild-type p53 are more resistant to induction of apoptosis by some agents. Blood 1993; 82: 1092-1096.
14. Lotem J, Sachs L. Regulation by bcl-2, c-myc and p53 of susceptibility to induction of apoptosis by heat shock and cancer chemotherapy compounds in differentiation-competent and detective myeloid leukemic cells. Cell Growth Differ 1993; 4: 41-47.
15. Yonish-Rouach E et al. p53 mediated cell death: relationship to cell cycle control. Mol Cell Biol 1993; 13: 1415-1423.
16. Lotem J, Sachs L. Selective regulation of the activity of different hematopoietic regulatory proteins by transforming growth factor β1 in normal and leukemic myeloid cells. Blood 1990; 76: 1315-1322.
17. Sen GC, Lengyel P. The Interferon system. J Biol Chem 1992; 267: 5017-5020.
18. Trinchieri C, Perussia B. Immune interferon: a pleiotropic lymphokine with multiple effects, Immunol Today 1985; 6: 131-136.
19. Yamamoto-Yamaguchi Y, Tomida M, Hozumi M. Contrasting effect of IFN-γ and IFN-α/β on differentiation of some clones of mouse myeloid leukemic cells. Leuk Res 1989; 13: 253-257.
20. Ichikawa Y. Differentiation of a cell line of myeloid leukemia. J Cell Physiol 1969; 74: 223-234.
21. Fibach E, Hayashi M, Sachs L. Control of normal differentiation of myeloid leukemic cells to macrophages and granulocytes. Proc Natl Acad Sci USA 1973; 70: 343-346.
22. Michalovitz D, Halevy O, Oren M. Conditional inhibition of transformation and cell proliferation by a temperature-sensitive mutant of p53. Cell 1990; 62: 671-680.
23. Lotem J, Sachs L. Genetic dissection of the control of normal differentiation in myeloid leukemic cells. Proc Natl Acad Sci USA 1977; 74: 5554-5558.
24. + myeloid leukemic cells. J Cell Physiol 1977; 92: 97-108.
25. Lotem J, Sachs L. Control of sensitivity to induction of apoptosis in myeloid leukemic cells by differentiation and bcl-2 dependent and independent pathways. Cell Growth Differ 1994; 5: 321-327.
26. Nunez C et al. Deregulated Bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines. J Immunol 1990; 144: 3602-3610.
27. El-Deiry WS et al. WAF-1, a potential mediator of p53 tumor suppression. Cell 1993; 75: 817-825.
28. Nudel U et al. The nucleotide sequence of the rat cytoplasmic β-actin gene. Nucleic Acid Res 1983; 11: 1759-1771.
29. Rigby PWJ, Diekmann M, Rhodes C, Berg P. Labelling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase. J Mol Biol 1977; 113: 237-251.
30. Lowe SW et al. p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 1993; 362: 847-849.
31. Clarke AR et al. Thymocyte apoptosis induced by p53-dependent or -independent pathways. Nature 1993; 362: 849-852.
32. Zhu Y-M, Bradbury DA, Russell NH. Wild-type p53 is required for apoptosis induced by growth factor deprivation in factor-dependent leukaemic cells. Br J Cancer 1994; 69: 468-472.
33. Cottlieb E et al. Down-regulation of wild-type p53 activity interferes with apoptosis in IL-3-dependent hematopoietic cells following IL-3 withdrawal. EMBO J 1994; 13: 1368-1374.
34. Ihle JN. The Janus kinase family and signalling through members of the cytokine receptor superfamily. Proc Soc Exp Biol Med 1994; 206: 268-272.
35. Darnell JE, Kerr IM, Stark GR. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signalling proteins. Science 1994; 264: 1415-1421.
36. Ruhl S, Pluznik DH. Dissociation of early and late markers of murine myeloid differentiation by interferon-gamma and interleukin-6. J Cell Physiol 1993; 155: 130-138.
37. Buschle M et al. Interferon γ inhibits apoptotic cell death in B cell chronic lymphocytic leukemia. J Exp Med 1993; 177: 213-218.
38. Panayiotidis P, Ganeshaguru K, Jabbar SAB, Hoffbrand AV. Alpha-interferon (α-IFN) protects B-chronic lymphocytic leukaemia cells from apoptotic cell death in vitro. Br J Haematol 1994; 86: 169-173.
39. Vairo G, Argiriou S, Knight KR, Hamilton JA. Inhibition of colony stimulating factor-stimulated macrophage proliferation by tumor necrosis factor-α, IFN-γ, and lipopolysaccharide is not due to a general loss of responsiveness to growth factor. J Immunol 1991; 146: 3469-3477.
40. Mangan DF, Wahl SM. Differential regulation of human monocyte programmed cell death (apoptosis) by chemotactic factors and pro-inflammatory cytokines. J Immunol 1991; 147: 3408-3412.
41. Groux H et al. CD3 mediated apoptosis of human medullary thymocytes and activated peripheral T cells: respective roles of interleukin-1, interleukin-2, interferon-γ and accessory cells. Eur J Immunol 1993; 23: 1623-1629.
42. Novick D et al. Monoclonal antibodies to human interferon-γ: production, affinity, purification and radioimmunoassay. EMBO J 1983; 2: 1527-1530.
43. Novick D, Engelmann H, Wallach D, Rubinstein M. Soluble cytokine receptors are present in normal human urine. J Exp Med 1989; 170: 1409-1414.