G1 cyclin turnover and nutrient uptake are controlled by a common pathway in yeast

Genes and Development

Volumn 9, Issue 4, 1995, Pages 399-409

  Barral, Yves ^a,b   Jentsch, Stefan ^b,c   Mann, Carl ^a  

^a CENTRE D ETUDES DE SACLAY   (France)

^b FRIEDRICH MIESCHER LABORATORY OF THE MAX PLANCK SOCIETY   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

G1 cyclins; nutrient uptake; proteolysis

Indexed keywords

BETA GALACTOSIDASE; CYCLINE; HYBRID PROTEIN; PROTEIN KINASE; CARRIER PROTEIN; CLN1 PROTEIN, YEAST; CLN2 PROTEIN, YEAST; CLN3 PROTEIN, S CEREVISIAE; FUNGAL PROTEIN; GLUCOSE; GRR1 PROTEIN;

ARTICLE; CELL CYCLE G1 PHASE; CELL DIVISION; CELL GROWTH; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GENE ISOLATION; NONHUMAN; NUTRIENT; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN STABILITY; SACCHAROMYCES CEREVISIAE; CYTOLOGY; FLOW CYTOMETRY; FUNGAL GENE; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MORPHOGENESIS; NORTHERN BLOTTING; PHYSIOLOGY; SERODIAGNOSIS; TRANSPORT AT THE CELLULAR LEVEL;

SACCHAROMYCES CEREVISIAE;

BIOLOGICAL TRANSPORT; BLOTTING, NORTHERN; CARRIER PROTEINS; CYCLINS; FLOW CYTOMETRY; FUNGAL PROTEINS; G1 PHASE; GENES, FUNGAL; GLUCOSE; MORPHOGENESIS; PRECIPITIN TESTS; RECOMBINANT FUSION PROTEINS; SACCHAROMYCES CEREVISIAE; SUPPORT, NON-U.S. GOV'T;

EID: 0028986667     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.9.4.399     Document Type: Article

References (44)

1. Bailey, R.B. and A. Woodward. 1984. Isolation and characterization of a pleiotropic glucose repression resistant mutant of Saccharomyces cerevisiae. Mol. & Gen. Genet. 193: 507-512.
2. Baroni, M.D., P. Monti, and L. Alberghina. 1994. Repression of growth-regulated G1 cyclin expression by cyclic AMP in budding yeast. Nature 371: 339-342.
3. Boeke, J.D., F. Lacroute, and G.R. Fink. 1984. A positive selection for mutants lacking orotidine-5′-phosphate decarboxylase activity in yeast: 5-Fluoro-orotic acid resistance. Mol. & Gen. Genet. 197: 345-346.
4. Church, G.M. and W. Gilbert. 1984. Genomic sequencing. Proc. Natl. Acad. Sci. 81: 1991-1995.
5. Conklin, D.S., C. Kung, and M.R. Culbertson. 1993. The COT2 gene is required for glucose-dependent divalent cation transport in Saccharomyces cerevisiae. Mol. Cell. Biol. 13: 2041-2049.
6. Cross, F. 1988. DAF1, a mutant gene affecting size control, pheromone arrest, and cell cycle kinetics of Saccharomyces cerevisiae. Mol. Cell. Biol. 8: 4675-4684.
7. Cross, F. and C.M. Blake. 1993. The yeast Cln3 protein is an unstable activator of Cdc28. Mol. Cell. Biol. 13: 3266-3271.
8. Cross, F. and A. Tinkelenberg. 1991. A potential positive feedback loop controlling CIN1 and CLN2 gene expression at the start of the yeast cell cycle. Cell 65: 875-883.
9. Cross, F.R., M. Hoek, J.D. McKinney, and A.H. Tinkelenberg. 1994. Role of Swi4 in cell cycle regulation of CLN2 expression. Mol. Cell. Biol. 14: 4779-4787.
10. Dirick, L. and K. Nasmyth. 1991. Positive feedback in the activation of G1 cyclins in yeast. Nature 351: 754-757.
11. Erickson, J.R. and M. Johnston. 1994. Suppressors reveal two classes of glucose repression genes in the yeast Saccharomyces cerevisiae. Genetics 136: 1271-1278.
12. Field, J., J.-I. Nikawa, D. Broek, B. MacDonald, L. Rodgers, I.A. Wilson, R.A. Lerner, and M. Wigler. 1988. Purification of a RAS-reponsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method. Mol. Cell. Biol. 8: 2159-2165.
13. Flick, J.S. and M. Johnston. 1991. GRR1 of Saccharomyces cerevisiae is required for glucose repression and encodes a protein with leucine-rich repeats. Mol. Cell. Biol. 11: 5101-5112.
14. Gancedo, J.M. 1992. Carbon catabolite repression in yeast. Eur. J. Biochem. 206: 297-313.
15. Gietz, D., A. St. Jean, R.A. Woods, and R.H. Schiestl. 1992. Improved method for high efficiency transformation of intact yeast cells. Nucleic Acids Res. 20: 1425.
16. Gimeno, C.J., P.O. Ljungdahl, C.A. Styles, and G.R. Fink. 1992. Unipolar cell divisions in the yeast S. cerevisiae lead to filamentous growth: Regulation by starvation and RAS. Cell 68: 1077-1090.
17. Glotzer, M., A.W. Murray, and M.W. Kirschner. 1991. Cyclin is degraded by the ubiquitin pathway. Nature 349: 132-138.
18. Hadwiger, J.A., C. Wittenberg, H.E. Richardson, M. De Barros Lopes, and S.I. Reed. 1989. A family of cyclin homologs that control the G1 phase in yeast. Proc. Natl. Acad. Sci. 86: 6255-6259.
19. Hovland, P., J. Flick, M. Johnston, and R.A. Sclafani. 1989. Galactose as a gratuitous inducer of GAL gene expression in yeasts growing on galactose. Gene 83: 57-64.
20. Johnson, S.J. 1991. "Structure and function analysis of the yeast CDC4 gene product." Ph.D. thesis, University of Washington, Seattle, WA.
21. Johnston, L. 1992. Cell cycle control of gene expression in yeast. Trends Cell Biol. 2: 353-357.
22. Lawrence, C.W. 1991. Classical mutagenesis techniques. Methods Enzymol. 194: 273-281.
23. Lew, D.J. and S.I. Reed. 1993. Morphogenesis in the yeast cell cycle: Regulation by Cdc28 and cyclins. J. Cell biol. 120: 1305-1320.
24. Mann, C., J.-Y. Micouin, N. Chiannilkulchai, I. Treich, J.-M. Buhler, and A. Sentenac. 1992. RPC53 encodes a subunit of Saccharomyces cerevisiae RNA polymerase C (III) whose inactivation leads to a predominantly G1 arrest. Mol. Cell. Biol. 125: 4314-4326.
25. Marshall-Carlson, L., L. Neigeborn, D. Coons, L. Bisson, and M. Carlson. 1991. Dominant and recessive suppressors that restore glucose transport in a yeast snf3 mutant. Genetics 1991: 505-512.
26. Nash, R., G. Tokiwa, S. Anand, K. Erickson, and A.B. Futcher. 1988. The WHI1+ gene of Saccharomyces cerevisiae tethers cell division to cell size and is a cyclin homolog. EMBO J. 13: 4335-4346.
27. Nasmyth, K. and L. Dirick. 1991. The role of SW14 and SW16 in the activity of G1 cyclins in yeast. Cell 66: 995-1013.
28. Ogas, I., B.J. Andrews, and I. Herskowitz. 1991. Transcriptional activation of CLN1, CLN2 and a putative new G1 cyclin (HCS26) by SW14, a positive regulator of G1-specific transcription. Cell 66: 1015-1026.
29. Ozcan, S., F. Schulte, K. Freidel, A. Weber, and M. Ciriacy. 1994. Glucose uptake and metabolism in grr1/cat80 mutants of Saccharomyces cerevisiae. Eur. J. Biochem. 224: 605-611.
30. Pringle, J.R., A.E.M. Adams, D.G. Drubin, and B.K. Haarer. 1991. Immunofluorescence methods for yeast. Methods Enzymol. 194: 565-602.
31. Pringle, J.R. and L.H. Hartwell. 1981. The Saccharomyces cerevisiae cell cycle. In The molecular biology of the yeast Saccharomyces (ed. J.N. Strathern, E.W. Jones, and J.R. Broach), Vol. 1. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.
32. Reed, S.I. 1992. The role of p34 kinases in the G1 to S-phase transition. Annu. Rev. Cell Biol. 8: 529-561.
33. Rogers, S., R. Wells, and M. Rechsteiner. 1986. Amino acid sequences common to rapidly degraded proteins: The PEST hypothesis. Science 234: 364-368.
34. Rose, A.B. and J.R. Broach. 1990. Propagation and expression of cloned genes in yeast: 2-μm circle-based vectors. Methods Enzymol. 185: 234-279.
35. Schmitt, M.E., T.A. Brown, and B.L. Trumpower. 1990. A rapid and simple method for preparation of RNA from Saccharomyces cerevisiae. Nucleic Acids Res. 18: 3091.
36. Sherman, F. 1991. Getting started with yeast. Methods Enzymol. 194: 3-21.
37. Stuart, D. and C. Wittenberg. 1994. Cell cycle-dependent transcription of CLN2 is conferred by multiple distinct cis-acting regulatory elements. Mol Cell. Biol. 14: 4788-4801.
38. Sudbery, P.E., A.R. Goodey, and B.L.A. Carter. 1980. Genes which control cell proliferation in the yeast Saccharomyces cerevisiae. Nature 288: 401-404.
39. Surana, U., A. Amon, C. Dowzer, J. McGrew, B. Byers, and K. Nasmyth. 1993. Destruction of the CDC28/CLB mitotic kinase is not required for the metaphase to anaphase transition in budding yeast. EMBO J. 12: 1969-1978.
40. Tokiwa, G., M. Tyers, T. Volpe, and B. Futcher. 1994. Inhibition of G1 cyclin activity by the Ras/cAMP pathway in yeast. Nature 371: 342-345.
41. Tyers, M., G. Tokiwa, and B. Futcher. 1993. Comparison of the Saccharomyces cerevisiae G1 cyclins: Cln3 may be an upstream activator of Cln1, Cln2 and other cyclins. EMBO J. 12: 1955-1968.
42. Tyers, M., G. Tokiwa, R. Nash, and B. Futcher. 1992. The Cln3-Cdc28 kinase complex of S. cerevisiae is regulated by proteolysis and phosphorylation. EMBO J. 11: 1773-1784.
43. Vallier, L. G., D. Coons, L.F. Bisson, and M. Carlson. 1994. Altered regulatory responses to glucose are associated with a glucose transport defect in grr1 mutants of Saccharomyces cerevisiae. Genetics 136: 1279-1285.
44. Wittenberg, C., K. Sugimoto, and S.I. Reed. 1990. G1-specific cyclins of S. cerevisiae: Cell cycle periodicity, regulation by mating pheromone, and association with the p34-CDC28 protein kinase. Cell 62: 225-237.