Detection of hypoxia by measurement of DNA damage in individual cells from spheroids and murine tumours exposed to bioreductive drugs. I. Tirapazamine

British Journal of Cancer

Volumn 71, Issue 3, 1995, Pages 529-536

  Olive, P L ^a  

^a BRITISH COLUMBIA CANCER RESEARCH CENTRE   (Canada)

Author keywords

Bioreductive drugs; DNA damage; Spheroids; Sr 4233; Tumour hypoxia

Indexed keywords

AGAROSE; DOUBLE STRANDED DNA; RADIOSENSITIZING AGENT; SINGLE STRANDED DNA; TIRAPAZAMINE;

ANIMAL CELL; ARTICLE; BLOOD VESSEL; CHINESE HAMSTER; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; ELECTRIC FIELD; FLUORESCENCE MICROSCOPY; HYPOXIC CELL; IMAGE ANALYSIS; LUNG FIBROBLAST; MULTICELLULAR SPHEROID; NONHUMAN; OXYGENATION; PRIORITY JOURNAL; TUMOR CELL;

ANIMAL; ANTINEOPLASTIC AGENTS; BENZIMIDAZOLES; CARCINOMA, SQUAMOUS CELL; CELL HYPOXIA; CELLS, CULTURED; CRICETULUS; DNA; DNA DAMAGE; DNA REPAIR; DNA, NEOPLASM; FIBROBLASTS; FLOW CYTOMETRY; FLUORESCENT DYES; HAMSTERS; KINETICS; MALE; MICE; MICE, INBRED C3H; NEOPLASM TRANSPLANTATION; SUPPORT, U.S. GOV'T, P.H.S.; TRIAZINES;

EID: 0028986423     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.1995.105     Document Type: Article

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