Characterization of benzo[a]pyrene quinone-induced toxicity to primary cultured bone marrow stromal cells from DBA/2 mice: Potential role of mitochondrial dysfunction

Toxicology and Applied Pharmacology

Volumn 130, Issue 1, 1995, Pages 108-120

  Zhu, Hong ^a   Li, Yunbo ^a   Trush, Michael A ^a  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,2 DITHIOLE 3 THIONE DERIVATIVE; ADENOSINE TRIPHOSPHATE; BENZO[A]PYRENE DERIVATIVE; BUTHIONINE SULFOXIMINE; GLUTATHIONE; QUINONE DERIVATIVE;

ANIMAL CELL; ARTICLE; BLOOD TOXICITY; BONE MARROW CELL; CELL CULTURE; CELL SURVIVAL; CONTROLLED STUDY; CYTOTOXICITY; MALE; METABOLITE; MITOCHONDRION; MOUSE; NONHUMAN; STROMA CELL;

ADENOSINE TRIPHOSPHATE; ANEMIA, APLASTIC; ANIMAL; ANTIMETABOLITES, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS; BENZO(A)PYRENE; BENZOPYRENES; BONE MARROW; BONE MARROW CELLS; BUTHIONINE SULFOXIMINE; CELL SURVIVAL; CELLS, CULTURED; DICUMAROL; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUTATHIONE; LEUKEMIA, EXPERIMENTAL; MALE; METHIONINE SULFOXIMINE; MICE; MICE, INBRED DBA; MITOCHONDRIA; NAD(P)H DEHYDROGENASE (QUINONE); QUINONES; STROMAL CELLS; SUPEROXIDE DISMUTASE; SUPPORT, U.S. GOV'T, P.H.S.; THIONES; THIOPHENES;

EID: 0028985277     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1006/taap.1995.1015     Document Type: Article

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