A physiological role for GABAB receptors and the effects of baclofen in the mammalian central nervous system

Progress in Neurobiology

Volumn 46, Issue 4, 1995, Pages 423-462

  Misgeld, Ulrich ^a   Bijak, Maria ^b   Jarolimek, Wolfgang ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b INSTITUTE OF PHARMACOLOGY   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

3 AMINOPROPYL(DIETHOXYMETHYL)PHOSPHINIC ACID; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID B RECEPTOR; 4 AMINOPYRIDINE; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; BACLOFEN; BARIUM; BENZYL[3 [[(3,4 DICHLOROPHENYL)ETHYL]AMINO] 2 HYDROXYPROPYL]PHOSPHINIC ACID; BENZYL[3 [[1 (3,4 DICHLOROPHENYL)ETHYL]AMINO] 2 HYDROXYPROPYL]PHOSPHINIC ACID; BICUCULLINE; CADMIUM; CARBACHOL; CESIUM; CGP 54062; MUSCIMOL; PHACLOFEN; PHENYLEPHRINE; POTASSIUM; SACLOFEN; TETRODOTOXIN; UNCLASSIFIED DRUG; AUTORECEPTOR; RECEPTORS, GABA B;

ANIMAL TISSUE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; MAMMAL; NONHUMAN; PRIORITY JOURNAL; REVIEW; ANIMAL; DRUG EFFECT; PHYSIOLOGY; POTASSIUM CHANNEL;

ANIMAL; AUTORECEPTORS; BACLOFEN; CENTRAL NERVOUS SYSTEM; POTASSIUM CHANNELS; RECEPTORS, GABA-B; SUPPORT, NON-U.S. GOV'T;

EID: 0028983775     PISSN: 03010082     EISSN: None     Source Type: Journal    
DOI: 10.1016/0301-0082(95)00012-K     Document Type: Review

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293. B agonist and serotonin in cultured hippocampal neurons
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295. The effect of baclofen and somatostatin on neuronal activity in the rat ventromedial hypothalamic nucleus in vitro
296. Novel GABA responses from rod-driven retinal horizontal cells
297. Inhibitory transmission in the basolateral amygdala
298. B, receptor regulating the release of central neurotransmitters
299. B receptor subtypes modulate neurotransmitter release in the rat brain cortex
300. Involvement of a pertussis toxin-sensitive G-protein in the pharmacological properties of septo-hippocampal neurones
301. B receptor biochemistry
302. B receptors in isolated substantia nigra neurones
303. + conductance by kainate and quisqualate in rat CA3 hippocampal neurones
304. Properties of excitatory post-synaptic currents recorded in vitro from rat hippocampal interneurones
305. B agonists modulate a transient potassium current in cultured mammalian hippocampal neurones
306. + channels mediate an IPSP in dorsal horn neurones elicited by sensory stimulation
307. Two types of post-synaptic inhibition in pyriform cortex of the rabbit: Fast and slow inhibitory post-synaptic potentials
308. d-Baclofen: Is it an antagonist at baclofen receptors?
309. d-Baclofen is an antagonist at baclofen receptors mediating antinociception in the spinal cord
310. B receptors in partially disinhibited rat hippocampal slice cultures
311. Pre-synaptic inhibition of miniature excitatory synaptic currents by baclofen and adenosine in the hippocampus
312. Pre-synaptic inhibition of excitatory synaptic transmission mediated by α adrenergic receptors in area CA3 of the rat hippocampus in vitro
313. Consequences of prolonged afferent stimulation of the rat fascia dentata: Epileptiform activity in area CA3 of hippocampus
314. Responses of cells of the rat fascia dentata to prolonged stimulation of the perforant path: Sensitivity of hilar cells and changes in granule cell excitability
315. Synaptic connections of dentate granule cells and hilar neurons: Results of paired intracellular recordings and intracellular horseradish peroxidase injections
316. B receptors
317. B receptor-mediated inhibition of serotonin release in the rat brain
318. A receptor: Molecular biology reveals a complex picture
319. A receptor shows a ligand-gated receptor super-family
320. Baclofen blocks post-synaptic inhibition but not the effect of muscimol in the olfactory cortex
321. 2+ currents and synaptic transmission in cultured rat hippocampal neurones
322. GABA-induced responses in purkinje cell dendrites of the rabbit cerebellar slice
323. Reverse intrinsic activity of antagonists on G protein-coupled receptors
324. Physiological and morphological identification of a nonpyramidal hippocampal cell type
325. Aspects of vertebrate neuronal voltage-activated calcium currents and their regulation
326. B receptors on neurones in rat brain slices
327. B receptors
328. Properties of rat medial septal neurones recorded in vitro
329. Repetitive inhibitory post-synaptic potentials evoked by 4-aminopyridine in hippocampal neurons in vitro
330. Serotonin attenuates a slow inhibitory post-synaptic potential in rat hippocampal neurons
331. A subset of local interneurons generate slow inhibitory post-synaptic potentials in hippocampal neurons
332. Potassium currents activated in hippocampal neurons by serotonin are mediated by a change in intracellular calcium concentrations
333. Epileptiform activity in microcultures containing small numbers of hippocampal neurons
334. B receptors and the ionic mechanisms mediating their effects on locus coeruleus neurons
335. Arachidonic acid cascade and signal transduction
336. Submicromolar concentrations of zinc irreversibly reduce a calcium-dependent potassium current in rat hippocampal neurons in vitro
337. GABA receptor mechanisms in the central nervous system
338. Uncultured lobster muscle, cultured neurons and brain slices: The neurophysoilogy of zinc
339. Bpmediated responses in the CA1 region of the rat hippocampal slice
340. Post-synaptic action of endogenous GABA released by nipecotic acid in the hippocampus
341. B receptors in the hippocampus: A reevaluation
342. B receptor-mediated responses in the lateral geniculate nucleus
343. +-dependent IPSP in cat and rat thalamic and hippocampal neurones
344. B IPSPs in the rat ventral lateral geniculate-nucleus
345. B inhibitory postsynaptic potential recorded in morphologically identified projection cells of the cat dorsal lateral geniculate-nucleus
346. Perforated patch-clamp analysis of the passive membrane properties of three classes of hippocampal neurons
347. Modulation of neurotransmitter release by pre-synaptic autoreceptors
348. Long-term potentiation of excitatory and slow inhibitory synaptic potentials in the hippocampal-septal projection of the rat
349. Further studies on the action of baclofen on neurons of the dorsolateral septal nucleus of the rat, in vitro
350. In vitro studies of the role of γ-aminobutyric acid in inhibition in the lateral septum of the rat
351. Distinct muscarinic receptors inhibit release of γ-aminobutyric acid and excitatory amino acids in mammalian brain
352. B receptors originate from discrete afferent neurons
353. Effects of glycine and GABA on isolated bipolar cells of the mouse retina
354. Baclofen suppresses hippocampal epileptiform activity at low concentrations without suppressing synaptic transmission
355. + channel critical for activation by G protein βγ subunits
356. Sensitivities of Achatina giant neurones to putative amino acid neurotransmitters
357. Effect of baclofen enantiomorphs on the spinal trigeminal nucleus and steric similarities of carbamazepine
358. Reversal properties of an EGTA-resistant late hyperpolarization that follows synaptic stimulation of hippocampal neurons
359. 3 neurons
360. Evidence that guanosine triphosphate (GTP)-binding proteins control a synaptic response in brain: Effect of pertussis toxin and GTPγS on the late inhibitory post-synaptic potential of hippocampal CA3 neurons
361. A late increase in potassium conductance follows synaptic stimulation of granule neurons of the dentate gyrus
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363. Cl− in hippocampal CA3 neurons
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366. Pre-synaptic inhibition in the hippocampus
367. Characterization of synaptically mediated fast and slow inhibitory processes in piriform cortex in an in vitro slice preparation
368. B binding in rat brain
369. Somatostatin induced hyperpolarization of septal neurons is not blocked by pertussis toxin
370. baclofen and adenosine inhibit synaptic potentials mediated by γ-aminobutyric acid and glutamate release in rat nucleus accumbens
371. Membrane properties and synaptic responses of the guinea pig nucleus accumbens neurons in vitro
372. o
373. Gamma-hydroxybutyrate a possible neurotransmitter
374. B receptors are coupled to a barium-insensitive outward rectifying potassium conductance in premotor respiratory neurons
375. Pre-synaptic GABA receptors
376. GABA release in rat cortical slices is unable to cope with demand if the autoreceptor is blocked
377. B autoreceptors: Some intriguing findings and their possible implications
378. B receptor antagonist with similar potency: no evidence for pharmacologically different presynaptic receptors
379. B antagonists
380. Phaclofen-insensitive presynaptic inhibitory action of (+/−)-baclofen in neonatal rat motoneurones in vitro
381. Inhibitory responses of rat basolateral amygdaloid neurons recorded in vitro
382. B autoreceptor activation
383. Bicuculline- and phaclofen-resistant hyperpolarizations evoked by glutamate applications to stratum lacunosum-moleculare in CA1 pyramidal cells of the rat hippocampus in vitro
384. B receptor-mediated inhibitory post-synaptic potentials evoked by electrical stimulation and by glutamate stimulation of interneurons in stratum lacunosum-moleculare in hippocampal CA1 pyramidal cells in vitro
385. Voltage- and ligand-activated inwardly rectifying currents in dorsal raphe neurons in vitro
386. Inward rectification of resting and receptor-linked potassium currents in rat locus coeruleus neurons
387. A dopaminergic inhibitory post-synaptic potential mediated by an increased potassium conductance
388. B receptors in physiology and pathology
389. Islet-activation protein inhibits the β-adrenergic receptor facilitation elicited by γ-aminobutyric acid B receptors
390. Baclofen inhibits with high affinity anl-type-like voltage-dependent calcium channel in cerebellar granule cell cultures
391. Cholinergic phosphatidylinositol modulation of inhibitory, G protein-linked, neurotransmitter actions: Electrophysiological studies in rat hippocampus
392. A physiological role for endogenous zinc in rat hippocampal synaptic neurotransmission
393. B receptors
394. B receptor
395. Properties of GABA-activated whole-cell currents in bipolar cells of the rat retina
396. The modulation of rat hippocampal synaptic conductances by baclofen and γ-aminobutyric acid
397. 5-Hydroxytryptamine mediates inhibitory post-synaptic potential in rat dorsal raphe neurons