Lysosomal Proteases Cathepsins D, B, H, L and Their Inhibitors Stefins A and B in Head and Neck Cancer

Biological Chemistry Hoppe-Seyler

Volumn 376, Issue 7, 1995, Pages 401-406

  Kos, Janko ^a   Krasovec, Marta ^a   Svetic, Branka ^a   Lenarcic, Brigita ^a   Turk, Vito ^a   Smid, Alojz ^b   Vrhovec, Ivan ^c   Skrk, Janez ^c  

^a JO EF STEFAN INSTITUTE   (Slovenia)

^b University Department of Otorhinolaryngology and Cervicofacial Suraerv ^*  (Slovenia)

^c Institute of Oncoloav ^*  (Slovenia)

Author keywords

Cathepsins B; D Head and neck tumours Stefins; H; L

Indexed keywords

CATHEPSIN; CYSTATIN; PROTEINASE INHIBITOR; STEFIN; STEFIN A;

ADENOCARCINOMA; ARTICLE; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYMOLOGY; HEAD AND NECK TUMOR; HUMAN; LYSOSOME; METABOLISM; SQUAMOUS CELL CARCINOMA;

ADENOCARCINOMA; CARCINOMA, SQUAMOUS CELL; CATHEPSINS; CYSTATINS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HEAD AND NECK NEOPLASMS; HUMAN; LYSOSOMES; PROTEASE INHIBITORS; SUPPORT, NON-U.S. GOV'T;

EID: 0028982065     PISSN: 01773593     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/bchm3.1995.376.7.401     Document Type: Article

References (25)

1. Azzopardi, J.G., Chepizk, O.F., and Hartman, W.H. (1981). International Histological Classification of Tumours No.2: Histological typing of breast tumours. 2nd ed. (Geneva: World Health Organisation).
2. Barrett, A.J., Rawlings, N.D., Davies, M.E., Machleidt, W., Salve-sen, G., and Turk, V. (1986). Cysteine proteinase inhibitors of cystatin superfamily. In: Protease Inhibitors, A.J. Barrett and G. Salvesen, eds. (Amsterdam, The Netherlands: Elsevier), pp. 514–549.
3. Bradford, M. (1976). A rapid sensitive method for the quantification of μg quantities of protein utilising the principle of protein-dye binding. Anal. Biochem. 72, 248–254.
4. Buck, M.R., Karustis, D.G., Day, N.A., Honn, K.V., and Sloane, B.F. (1992). Degradation of extracellular matrix proteins by human cathepsin B from normal and tumour tissues. Biochem J. 282, 273–279.
5. EORTC Breast Cancer Cooperative Group (1980). Revision of the standards for the assessments of hormon receptors in human breast cancer. Eur. J. Cancer 16,1513-1515.
6. Gabrijelcic, D., Svetic, B., Spaic, D., Skrk, J., Budihna, M., Dolenc, I., Popovic, T., Cotic, V., and Turk, V. (1992). Cathepsins B, H and L in human breast carcinoma. Eur. J. Clin. Chem. Clin. Biochem. 30,69-74.
7. Hermanek, P., and Sobin, L. (1987). TNM Classification of Malignant Tumours. International Union Against Cancer (UICC), 4th ed., (Berlin, Germany: Springer Verlag)
8. Jerala, R., Zerovnik, E., Lohner, K., and Turk, V. (1994). Structural basis for the difference in thermodynamic properties between the two cysteine proteinase inhibitors human stefins A and B. Protein Engineering £977-984.
9. Koga, H., Mori, N., Yamada, H., Nishimura, Y., Tokuda, K., Kato, K., and Imoto.T. (1992). Endo- and aminopeptidase activites of rat cathepsin H. Chem. Pharm. Bull. 40,965-970.
10. Kopitar-Jerala, N., Curin-Serbec, V., Jerala, R., Krizaj, I., Guben-sek, F., and Turk, V. (1993). Monoclonal antibodies to human stefin B and determination of their epitopes. Biochem Biophys. Acta 64,75-80.
11. Lah, T.T., Buck, M.R., Honn, K.V., Crissman, J.D., Rao, N.C., Liotta, L.A., and Sloane, B.F. (1989a). Degradation of laminin by human tumour cathepsin B. Clin. Exp. Metastases 7,461 -468.
12. Lah, T.T., Clifford, J.L., Helmer, K.M., Day, N.A., Moin, K., Honn, K.V., Crissman, J.D., and Sloane, B.F. (1989b). Inhibitory properties of low-molecular-mass cysteine proteinase inhibitors from human sarcoma. Biochem. Biophys. Acta 993,63-73.
13. Muller, D., Breathnach, R., Engelmann, A., Millon, R., Bronner, G., Flesch, H., Dumont, P., Eber, M., and Abecassis, J. (1991). Expression of collagenase-related metalloproteinase genes in human lung or head and neck tumours Int. J. Cancer 48, 550–556.
14. Pollete, M., Clavael, C., Muller, D., Abecassis, J., Binninger, I., and Birembaut, P. (1991). Detection of mRNAs encoding collagenase I and stromelysin 2 in carcinomas of head and neck by in situ hybridisation. Invasion Metastasis 11,76-83.
15. Popovic, T., Brzin, J., Kos, J., Lenarcic, B., Machleidt, W., Ritonja, A., Hanada, K., and Turk, V. (1988). A new purification procedure of human kidney cathepsin H, its properties and kinetic data. Biol. Chem. Hoppe-Seyler 371,575-580.
16. Rubin-Grandis, J., and Tweardy, D.J. (1993). Elevated levels of transforming growth factor a and epidermal growth factor receptor messenger RNA are early markers of carcinogenesis in head and neck cancer. Cancer Res. 53,3579-3584.
17. Sivaparvathi, M., Sawaya, R., Wang, S.W., Rayford, A., Yamamoto, M., Liotta, L.A., Nicolson, G.L., and Rao, J.S. (1995). Overexpression and localisation of cathepsin B during the progression of human gliomas. Clin. Exp. Metastasis 13, 49–56.
18. Spyratos, F., Maudelonde.T., Brouillet, J.P., Brunet, M., Defrenne, A., Andrieu, C., Hacene, K., Desplaces, A., Rouesse, J., and Rochefort, H. (1989). Cathepsin D: An independent prognostic factor for metastasis of breast cancer. The Lancet 8672,1115—1118.
19. Schmitt, M., Janicke, F., and Graeff, F. (1992). Tumor-associated proteases. Fibrynolysis 6, Suppl. 4,3-26.
20. Sloane, B.F., Moin, K., and Lah, T.T. (1994). Regulation of lysosomal endopeptidases in malignant neoplasia. In: Biochemical and Molecular Aspects of Selected Cancers, T.G. Pretlow and T.P. Pretlow, eds., (New York, USA: Academic Press), pp. 411 -472.
21. Thomssen, C., Schmitt, M., Goretzki, L., Oppelt, P., Janicke, F., Pache, L., and Graeff, H. (1995). Prognostic value of the cysteine proteases cathepsin B and L in human breast cancer. Clin. Cancer Res., in press.
22. Turk, B., Dolenc, I., Turk, V., and Bieth, G.J. (1993). Kinetics of pH-induced inactivation of human cathepsin L. Biochemistry 32, 375–380.
23. Turk, V., and Bode, W. (1993). Human cysteine proteinases and their inhibitors, stefins and cystatins. In: Innovations in Pro-teases and Their Inhibitors, F.X. Aviles, ed. (Berlin, New York: W. de Gruyter), pp. 47–59.
24. Werle, B., Ebert, W., Klein, W., and Spiess, E. (1994). Cathepsin B in tumors, normal tissue and isolated cells from the human lung. Anticancer Research 14,1169-1176.
25. Zeillinger, R., Swoboda, H., Machacek, E., Nekahm, D., Sliutz, G., Knogler, W., Speiser, P., Swoboda, E., and Kubista, E. (1992). Expression of cathepsin D in head and neck cancer. Eur. J. Cancer 28A, 1413–1415.