The function of a highly-conserved arginine residue in activation of the muscarinic M1 receptor

European Journal of Pharmacology: Molecular Pharmacology

Volumn 288, Issue 3, 1995, Pages 251-257

  Jones, Philip G ^a   Curtis, Carol A M ^a   Hulme, Edward C ^a  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

Arginine; G protein; Muscarinic receptor; Mutation

Indexed keywords

3 (3 AMINO 1,2,4 OXADIAZOL 5 YL)QUINUCLIDINE; 3 (3 METHYL 1,2,4 OXADIAZOL 5 YL)QUINUCLIDINE; ACETYLCHOLINE; ALANINE; ARGININE; CARBACHOL; DIVALENT CATION; GLUTAMIC ACID; GLUTAMINE; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); LEUCINE; LYSINE; METHYLFURTRETHONIUM; METHYLSCOPOLAMINE; MUSCARINIC AGENT; MUSCARINIC M1 RECEPTOR; MUSCARINIC RECEPTOR BLOCKING AGENT; MUTANT PROTEIN; OXOTREMORINE M; PHOSPHATIDYLINOSITIDE; PILOCARPINE; RADIOISOTOPE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; GENE EXPRESSION; LIGAND BINDING; NONHUMAN; PHOSPHOINOSITIDE METABOLISM; PRIORITY JOURNAL; PROTEIN STRUCTURE; RECEPTOR AFFINITY; SITE DIRECTED MUTAGENESIS;

ACETYLCHOLINE; AMINO ACID SEQUENCE; ANIMAL; ARGININE; CARBACHOL; CATIONS, DIVALENT; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; GTP-BINDING PROTEINS; HYDROLYSIS; MOLECULAR SEQUENCE DATA; MUSCARINIC AGONISTS; MUTATION; N-METHYLSCOPOLAMINE; PHOSPHATIDYLINOSITOLS; RATS; RECEPTORS, MUSCARINIC; SCOPOLAMINE DERIVATIVES; SUPPORT, NON-U.S. GOV'T;

EID: 0028981397     PISSN: 09224106     EISSN: None     Source Type: Journal    
DOI: 10.1016/0922-4106(95)90036-5     Document Type: Article

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