Adenomatous Polyposis Coli Gene Mutations in Ulcerative Colitis-associated Dysplasias and Cancers versus Sporadic Colon Neoplasms

Cancer Research

Volumn 55, Issue 10, 1995, Pages 2035-2038

  Tannin, Lila ^a   Yin, Jing ^a   Kozam, Marc ^a   Noordzij, Jeroen ^a   Jiang, Hai Yan ^a   Meltzer, Stephen J ^a   Harpaz, Noam ^b   Antonio, Lilian B ^b   Chan, Olivia ^b   Cymes, Karína ^b  

^a UNIVERSITY OF MARYLAND   (United States)

^b MOUNT SINAI MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CANCER GENETICS; COLON CARCINOGENESIS; COLON POLYPOSIS; COLORECTAL CANCER; DYSPLASIA; GENE MUTATION; GENETIC ANALYSIS; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; ULCERATIVE COLITIS;

BASE SEQUENCE; CHROMOSOME DELETION; COLITIS, ULCERATIVE; COLONIC NEOPLASMS; GENES, APC; HUMAN; MOLECULAR SEQUENCE DATA; POINT MUTATION; PRECANCEROUS CONDITIONS; SEQUENCE ANALYSIS, DNA; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0028979727     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Lashner, B. A., Silverstein, M. D., and Hanauer, S. B. Hazard rates for dysplasia and cancer in ulcerative colitis: results from a surveillance program. Dig. Dis. Sci., 34: 1536-1541, 1989.
2. Meltzer, S. J., Mane, S. M., Wood, P. K., Resau, J. H., Newkirk, C., Terzakis, J. A., Korelitz, B. I., Weinstein, W. M., and Needleman, S. W. Activation of c-Ki-ras in gastrointestinal dysplasias determined by direct sequencing of polymerase chain reaction products. Cancer Res., 50: 3627-3630, 1990.
3. Greenwald, B. D., Harpaz, N., Yin, J., Huang, Y., Tong, Y., Brown, V. L., McDaniel, T., Newkirk, C., Resau, J. H., and Meltzer, S. J. Loss of heterozygosity affecting the p53, Rb, and MCC/APC tumor suppressor gene loci in dysplastic and cancerous ulcerative colitis. Cancer Res., 52: 741-745, 1992.
4. Suzuki, H., Harpaz, N., Tannin, L., Yin, J., Jiang, H.-Y., Bell, J. D., Hontanosas, M., Groisman, G. M., Abraham, J. M., and Meltzer, S. J. Microsatellite instability in ulcerative colitis-associated colorectal dysplasias and cancers. Cancer Res., 54: 4841-4844, 1994.
5. Kern, S. E., Redston, M., Seymour, A. B., Caldas, C., Powell, S. M., and Kornacki, S. Molecular genetic profiles of colitis associated neoplasms. Gastroenterology, 107: 420-428, 1994.
6. Fearon, E. R., and Volgelstein, B. A genetic model for colorectal tumorigenesis. Cell, 61: 759-767, 1990.
7. Vogelstein, B., Fearon, E. R., Hamilton, S. R., Kern, S. E., Preisinger, A. C., Leppert, M., Nakamura, Y., White, R., Smits, A. M. M., and Bos, J. L. Genetic alterations during colorectal tumor development. N. Engl. J. Med., 319: 525-532, 1988.
8. Harpaz, N., Peck, A. L. Yin, J., Fiel, I., Hontanosas, M., Tong, T. R., Laurin, J. N., Abraham, J. M., Greenwald, B. D., and Meltzer, S. J. p53 protein expression in ulcerative colitis-associated colorectal dysplasia and carcinoma. Hum. Pathol., 25: 1069-1074, 1994.
9. Baker, S. J., Preisinger, A. C., Jessup, J. M., Paraskeva, C., Markowitz, S., Wilson, J. K. V., Hamilton, S., and Volgelstein, B. p53 gene mutations occur in combination with 17p deletions as late events in colorectal tumorigenesis. Cancer Res., 50: 7717-7722, 1990.
10. Nishisho, I., Nakamura, Y., Miyoshi, Y., et al Mutations of chromosome 5q21 genes in FAP and colorectal cancer. Science (Washington DC), 253: 665-669, 1991.
11. Groden, J., Thliveris, A., Samowitz, W., et al. Identification and characterization of the familial adenomatous polyposis coli gene. Cell, 66: 589-600, 1991.
12. Joslyn, G., Carlson, M., Thliveris, A., et al Identification of deletion mutations and three new genes at the familial polyposis locus. Cell, 66: 601-613, 1991.
13. Miyoshi, Y., Nagase, H., Ando, H., Horii, A., Ichii, S., Nakatsuru, S., Aoki, T., Miki, Y., Mori, T., and Nakamura, Y. Somatic mutations of the APC gene in colorectal tumors: mutation cluster region in the APC gene. Hum. Mol. Genet., 1: 229-233, 1992.
14. Smith, K. J., Johnson, K. A., Bryan, T. M., et al. The APC gene product in normal and tumor cells. Proc. Natl. Acad. Sci. USA, 90: 2846-2850, 1993.
15. Miyoshi, Y., Ando, H., Nagase, H., et al. Germ-line mutations of the APC gene in 53 familial adenomatous polyposis patients. Proc. Natl. Acad. Sci. USA, 89:4452-4456, 1992.
16. Horii, A., Nakatsuru, S., Miyoshi, Y., Ichii, S., Nagase, H., Kato, Y., Yanagisawa, A., and Nakamura, Y. The APC gene, responsible for familial adenomatous polyposis, is mutated in human gastric cancer. Cancer Res., 52: 3231-3233, 1992.
17. Nakatsuru, S., Yanagisawa, A., Ichii, S., Tahara, E., Kato, Y., Nakamura, Y., and Horii, A. Somatic mutation of the APC gene in gastric cancer: frequent mutations in a very well differentiated adenocarcinoma and signet-ring cell carcinoma. Hum. Mol. Genet., 1: 559-563, 1992.
18. Horii, A., Nakatsuru, S., Miyoshi, Y., Ichii, S., Nagase, H., Ando, H., Yanagisawa, A., Tsuchiya, E., Kato, Y., and Nakamura, Y. Frequent somatic mutations of the APC gene in pancreatic cancer. Cancer Res., 52: 6696-6698, 1992.
19. Zeki, K., Spambalg, D., Sharifi, N., Gonsky, R., and Fagin, J. A. Mutations of the adenomatous polyposis coli gene in sporadic thyroid neoplasms. J. Clin. Endocrinol. Metab., 79: 1317-1321, 1994.
20. Weitzel, J. N., Patel, J., Smith, D. M., Goodman, A., Safaii, H., and Ball, H. G. Molecular genetic changes associated with ovarian cancer. Gynecol. Oncol., 55: 245-252, 1994.
21. Powell, S. M., Papadopoulos, N., Kinzler, K. W., Smolinski, K. N., and Meltzer, S. J. APC gene mutations in the mutation cluster region are rare in esophageal cancers. Gastroenterology, 107: 1759-1763, 1994.
22. Powell, S. M., Zilz, N., Beazer-Barclay, Y., Bryan, T. M., Hamilton, S. R., Thibodeau, S. N., Vogelstein, B., and Kinzler, K. W. APC mutations occur early during colorectal tumorigenesis. Nature (Lond.), 359: 237-237, 1992.
23. Powell, S. M., Petersen, G. M., Krush, A. J., Booker, S., Jen, J., Giardello, F. M., Hamilton, S. R., Vogelstein, B., and Kinzler, K. W. Molecular diagnosis of familial adenomatous polyposis. N. Engl. J. Med., 329: 1982-1987, 1993.
24. Vogelstein, B., Fearon, E. R., Kern, S. E., Hamilton, S. R., Preisinger, A. C., Nakamura, Y., and White, R. Allelotype of colorectal carcinomas. Science (Washington DC), 244: 207-211, 1989.
25. Meltzer, S. J., Mane, S. M., Wood, P. K., Resau, J. H., Newkirk, C., Terakis, J. A., Korelitz, B. I., Weinstein, W. M., and Needleman, S. M. Activation of c-Ki-ras in gastrointestinal dysplasias determined by direct sequencing of polymerase chain reaction products. Cancer Res., 50: 3627-3630, 1990.
26. Goelz, S. E., Hamilton, S. R., and Vogelstein, B. Purification of DNA from formaldehyde fixed and paraffin embedded human tissue. Biochem. Biophys. Res. Commun., 130: 118-126, 1985.
27. Meltzer, S. J., Yin, J., Huang, Y., McDaniel, T. K., Newkirk, C., Iseri, O., Vogelstein, B., and Resau, J. H. Reduction to homozygosity involving p53 in esophageal cancers demonstrated by the polymerase chain reaction. Proc. Natl. Acad. Sci. USA, 88: 4976-4980, 1991.
28. Boynton, R. F., Huang, Y., Blount, P. L., et al Frequent loss of heterozygosity at the retinoblastoma locus in human esophageal cancers. Cancer Res., 57: 5766-5769,1991.
29. Tannin, L., Yin, J., Zhou, X., Suzuki, H., Jiang, H.-Y., Abraham, J. M., Krasna, M. J., Cortrell, J., and Meltzer, S. J. Frequent loss of heterozygosity on chromosome 9 in adenocarcinoma and squamous cell carcinoma of the esophagus. Cancer Res., 54: 6094-6096, 1994.
30. Burmer, G. C., Rabinovitch, P. S., Haggitt, R. C., Crispin, D. A., Brentnall, T. A., Kolli, V. R., Stevens, A. C., and Rubin, C. E. Neoplastic progression in ulcerative colitis: histology, DNA content, and loss of a p53 allele. Gastroenterology, 103: 1602-1610, 1992.
31. Brentnall, T. A., Crispin, D. A., Rabinovitch, P. S., Haggitt, R. C., Rubin, C. E., Stevens, A. C., and Burmer, G. C. Mutations in the p53 gene: an early marker of neoplastic progression in ulcerative colitis. Gastroenterology, 707: 369-378, 1994.
32. Kern, S. E., Fearon, E. R., Tersmette, K. W. F., Enterline, J. P., Leppert, M., Nakamura, Y., White, R., Vogelstein, B., and Hamilton, S. R. Allelic loss in colorectal carcinoma. J. Am. Med. Assoc., 261: 3099-3103, 1989.
33. Hamelin, R., Laurent-Puig, P., Olschwang, S., Salmon, R. J., and Thomas, G. Genetic instability of microsatellites in human colon cancer. Gastroenterology, 106: A390, 1994.
34. Aaltonen, L. A., Peltomaki, P., Leach, F. S., et al Clues to the pathogenesis of familial colorectal cancer. Science (Washington DC), 260: 812-816, 1993.
35. Thibodeau, S. N., Bren, G., and Schaid, D. Microsatellite instability in cancer of the proximal colon. Science (Washington DC), 260: 816-819, 1993.
36. Ionov, Y., Peinado, M. A., Malkhosyan, S., Shibata, D., and Perucho, M. Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature (Lond.), 363: 558-561, 1993.
37. Schneider, A., and Stolte, M. Differential diagnosis of adenomas and dysplastic lesions in patients with ulcerative colitis. Gastroenterology, 31: 653-656, 1993.