A UV-responsive G2 checkpoint in rodent cells

Molecular and Cellular Biology

Volumn 15, Issue 7, 1995, Pages 3722-3730

  Orren, David K ^a   Petersen, Lone N ^a,b   Bohr, Vilhelm A ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b Mental Health Services CPH   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CHO CELL; DNA METABOLISM; GROWTH REGULATION; NONHUMAN; PRIORITY JOURNAL; ULTRAVIOLET IRRADIATION; ANIMAL; APOPTOSIS; CELL CYCLE G1 PHASE; DNA DAMAGE; DNA REPAIR; DRUG EFFECT; HAMSTER; METABOLISM; PHYSIOLOGY; RADIATION EXPOSURE; RADIATION RESPONSE; ULTRAVIOLET RADIATION;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS; MAMMALIA; RODENTIA;

MIMOSINE; PYRIMIDINE DIMER;

ANIMAL; APOPTOSIS; CHO CELLS; DNA DAMAGE; DNA REPAIR; DOSE-RESPONSE RELATIONSHIP, RADIATION; G1 PHASE; G2 PHASE; HAMSTERS; MIMOSINE; PYRIMIDINE DIMERS; S PHASE; SUPPORT, NON-U.S. GOV'T; ULTRAVIOLET RAYS;

EID: 0028979708     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.15.7.3722     Document Type: Article

References (58)

1. Adams, R. L. P. 1990. Cell synchronization, p. 211-238. In R. H. Burdon and P. H. van Knippenberg (ed.), Laboratory techniques in biochemistry and molecular biology, vol. 8. Cell culture for biochemists. Elsevier Press, New York.
2. 2 checkpoint pathways in Schizosaccharomyces pombe. EMBO J. 11:1343-1350.
3. Berger, C. A., and H. J. Edenberg. 1986. Pyrimidine dimers block simian virus 40 replication forks. Mol. Cell. Biol. 6:3443-3450.
4. Bohr, V. A., C. A. Smith, D. S. Okumoto, and P. C. Hanawalt. 1985. DNA repair in an active gene: removal of pyrimidine dimers from the DHFR gene of CHO cells is much more efficient than in the genome overall. Cell 40: 359-369.
5. Christians, F. C., and P. C. Hanawalt. 1992. Inhibition of transcription and strand-specific DNA repair by α-amanitin in Chinese hamster ovary cells. Mutat. Res. 274:93-101.
6. Clarke, A. R., C. A. Purdie, D. J. Harrison, R. G. Morris, C. C. Bird, M. L. Hooper, and A. H. Wylie. 1993. Thymocyte apoptosis induced by p53-dependent and independent pathways. Nature (London) 362:849-852.
7. Devary, Y., R. A. Gottlieb, T. Smeal, and M. Karin. 1992. The mammalian ultraviolet response is triggered by activation of scr tyrosine kinases. Cell 71:1081-1091.
8. Friedberg, E. C., G. C. Walker, and W. Siede. 1995. DNA repair and mutagenesis. ASM Press, Washington, D.C.
9. 1 phase of the cell cycle. Cell 67:293-303.
10. Griffiths, T. D., and S. Y. Ling. 1985. Effect of ultraviolet light on thymidine incorporation, DNA chain elongation and replicon initiation in wild-type and excision-deficient Chinese hamster ovary cells. Biochim. Biophys. Acta 826:121-128.
11. Griffiths, T. D., and S. Y. Ling. 1989. Effects of UV light on DNA chain growth and replicon initiation in human cells. Mutat. Res. 218:87-94.
12. Hartwell, L. 1992. Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells. Cell 71:543-546.
13. 3+ gene of Schizosaccharomyces pombe is involved in multiple checkpoint functions and in DNA repair. Proc. Natl. Acad. Sci. USA 89:4952-4956.
14. Kantor, G. J., and D. R. Hull. 1979. An effect of ultraviolet light on RNA and protein synthesis in nondividing human diploid fibroblasts. Biophys. J. 27: 359-370.
15. Kastan, M. B., O. Onyekwere, D. Sidransky, B. Vogelstein, and R. Craig. 1991. Participation of p53 protein in the cellular response to DNA damage. Cancer Res. 51:6304-6311.
16. Kastan, M. B., Q. Zhan, W. S. El-Deiry, F. Carrier, T. Jacks, W. V. Walsh, B. S. Plunkett, B. Vogelstein, and A. J. Fornace. 1992. A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-teleangiectasia. Cell 71:587-597.
17. Kauffman, M. G., S. J. Noga, T. J. Kelly, and A. D. Donnenberg. 1990. Isolation of cell cycle fractions by counterflow centrifugal elutriation. Anal. Biochem. 191:41-46.
18. Kaufman, R. J., and R. T. Schimke. 1981. Amplification and loss of dihydrofolate reductase genes in a Chinese hamster ovary cell line. Mol. Cell. Biol. 1:1069-1076.
19. Kaufmann, W. K., and J. E. Cleaver. 1981. Mechanisms of inhibition of DNA replication by ultraviolet light in normal human and xeroderma pigmentosum fibroblasts. J. Mol. Biol. 149:171-187.
20. 1 arrest and cell-cycle-dependent clastogenesis in UV-irradiated human fibroblasts. Mutat. Res. 314:67-76.
21. Konig, K., and H. Baisch. 1980. DNA synthesis and cell cycle progression of synchronized L-cells after irradiation in various phases of the cell cycle. Radiat. Environ. Biophys. 18:257-266.
22. 1 phase of the mammalian cell cycle. Exp. Cell Res. 186:332-339.
23. Lee, J. M., and A. Bernstein. 1993. p53 mutations increase resistance to ionizing radiation. Proc. Natl. Acad. Sci. USA 90:5742-5746.
24. Lehmann, A. R. 1972. Postreplication repair of DNA in ultraviolet-irradiated mammalian cells. J. Mol. Biol. 66:319-337.
25. Levinson, V., and J. L. Hamlin. Personal communication.
26. 2 arrest in Chinese hamster ovary cells. Cancer Res. 50:3761-3766.
27. Lowe, S. W., E. M. Schmitt, S. W. Smith, B. A. Osborne, and T. Jacks. 1993. p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature (London) 362:847-849.
28. Lu, X., and D. P. Lane. 1993. Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes? Cell 75:765-778.
29. Maltzman, W., and L. Czyzyk. 1984. UV irradiation stimulates levels of p53 cellular tumor antigen in nontransformed mouse cells. Mol. Cell. Biol. 4:1689-1694.
30. May, A., R. S. Nairn, D. S. Okumoto, K. Wassermann, T. Stevnsner, J. C. Jones, and V. A. Bohr. 1993. Repair of individual DNA strands in the hamster dihydrofolate reductase gene after treatment with ultraviolet light, alkylating agents, and cisplatin. J. Biol. Chem. 268:1650-1657.
31. Mayne, L. V., and A. R. Lebmann. 1982. Failure of RNA synthesis to recover after UV irradiation: an early defect in cells from individuals with Cockayne's syndrome and xeroderma pigmentosum. Cancer Res. 42:1473-1478.
32. Mellon, I., and P. C. Hanawalt. 1989. Induction of E. coli lactose operon selectively increases repair of its transcribed strand. Nature (London) 342: 95-98.
33. Mellon, I., G. Spivak, and P. C. Hanawalt. 1987. Selective removal of transcription-blocking DNA damage from the transcribed strand of the mammalian DHFR gene. Cell 51:241-249.
34. Miller, S. A., D. D. Dykes, and H. F. Polesky. 1988. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res. 16:1215.
35. Mitchell, D. L. 1988. The relative cytotoxicity of (6-4) photoproducts and cyclobutane dimers in mammalian cells. Photochem. Photobiol. 48:51-57.
36. Moore, P. D., K. K. Bose, S. D. Rabkin, and B. S. Strauss. 1981. Sites of termination of in vitro DNA synthesis on ultraviolet- and N-acetylaminofluorene-treated φX174 templates by prokaryotic and eukaryotic DNA polymerases. Proc. Natl. Acad. Sci. USA 78:110-114.
37. Mosca, P. J., P. A. Dijkwel, and J. L. Hamlin. 1992. The plant amino acid mimosine may inhibit initiation at origins of replication in Chinese hamster cells. Mol. Cell. Biol. 12:4375-4383.
38. Nelson, W. G., and M. B. Kastan. 1994. DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways. Mol. Cell. Biol. 14:1815-1823.
39. Painter, R. B. 1985. Inhibition and recovery of DNA synthesis in human cells after exposure to ultraviolet light. Mutat. Res. 145:63-69.
40. Painter, R. B., and B. R. Young. 1980. Radiosensitivity in ataxia telangiectasia: a new explanation. Proc. Natl. Acad. Sci. USA 77:7315-7317.
41. Petersen, L., and D. Orren. Unpublished data.
42. 2 phases of the cell cycle. Mol. Cell. Biol. 15:3731-3737.
43. Rowley, R., S. Subramani, and P. G. Young. 1992. Checkpoint controls in Schizosaccharomyces pombe: rad1. EMBO J. 11:1335-1342.
44. Sancar, A., and G. B. Sancar. 1988. DNA repair enzymes. Annu. Rev. Biochem. 57:29-67.
45. Selby, C. P., and A. Sancar. 1990. Transcription preferentially inhibits nucleotide excision repair of the template DNA strand in vitro. J. Biol. Chem. 265:21330-21336.
46. Setlow, R. B., and S. M. D'Ambrosio. 1978. Size of putative gaps in post-replication repair. Biophys. J. 21:94a.
47. 1 arrest defines a second checkpoint for damaged DNA in the cell cycle of Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 90:7985-7989.
48. 1 checkpoint does not decrease cell survival following DNA damage. Cancer Res. 53:4164-4168.
49. Spivak, G., and P. C. Hanawalt. 1992. Translesion DNA synthesis in the dihydrofolate reductase domain of UV-irradiated CHO cells. Biochemistry 31:6794-6800.
50. Sweder, K. S., and P. C. Hanawalt. 1992. Preferential repair of cyclobutane pyrimidine dimers in the transcribed strand of a gene in yeast chromosomes and plasmids is dependent on transcription. Proc. Natl. Acad. Sci. USA 89:10696-10700.
51. Terasima, T., and L. J. Tolmach. 1963. Variations in several responses of HeLa cells to X-irradiation during the division cycle. Biophys. J. 3:11-33.
52. 2 arrest upon UV irradiation. Mol. Cell. Biol. 10: 4678-4684.
53. 2. Nature (London) 254:245-247.
54. Weinert, T. A., and L. H. Hartwell. 1988. The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevisiae. Science 241: 317-322.
55. Weinert, T. A., and L. H. Hartwell. 1990. Characterization of RAD9 of Saccharomyces cerevisiae and evidence that its function acts posttranslationally in cell cycle arrest after DNA damage. Mol. Cell. Biol. 10:6554-6564.
56. Wyllie, A. H. 1980. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature (London) 284:555-556.
57. Yamada, M., and T. T. Puck. 1961. Action of radiation on mammalian cells. IV. Reversible mitotic lag in the S3 HeLa cell produced by low doses of X-rays. Proc. Natl. Acad. Sci. USA 47:1181-1191.
58. Zhan, Q., F. Carrier, and A. J. Fornace. 1993. Induction of cellular p53 activity by DNA-damaging agents and growth arrest. Mol. Cell. Biol. 13: 4242-4250.