Structure of the nf-κb p50 homodimer bound to dna

Nature

Volumn 373, Issue 6512, 1995, Pages 311-317

  Müller, Christoph W ^a,b   Van Duyne, Félix A ^b   Sodeoka, Mikiko ^b   Verdine, Gregory L ^b   Harrison, Stephen C ^a,b,c  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b HARVARD UNIVERSITY   (United States)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DIMER; IMMUNOGLOBULIN; TRANSCRIPTION FACTOR;

ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; DIMERIZATION; DNA HELIX; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; BASE SEQUENCE; COMPUTER GRAPHICS; CRYSTALLOGRAPHY, X-RAY; DNA; HUMAN; MOLECULAR SEQUENCE DATA; NF-KAPPA B; NUCLEIC ACID CONFORMATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-REL; RECOMBINANT PROTEINS; SUPPORT, NON-U.S. GOV'T;

EID: 0028979476     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/373311a0     Document Type: Article

References (48)

1. Sen, R. & Baltimore, D. Cell 48, 705-716 (1986).
2. Grilli, M., Chiu, J. J.-S. & Lenardo, J. J. Int. Rev. exp. Cytol. 143, 1-62 (1993).
3. Baeuerle, P. A. Biochim. biophys. Acta 1072, 63-80 (1991).
4. Ghosh, S. et al Cell 62, 1019-1029 (1990).
5. Kîeran, J. et al. Cell 82, 1007-1018 (1990).
6. Ruben, S. M. et al. Science 251, 1490-1493 (1991).
7. Nolan, G. P., Ghosh, S., Liou, H. C., Tempst, P. & Baltimore, D. Cell 84, 961-969 (1991).
8. Steward, R. Science 238, 692-694 (1987).
9. Urban, M. B., Schreck, R. & Baeuerle, P. A. EMBO J. 10, 1817-1825 (1991).
10. Perkins, N. D. et al. Proc. natn. Acad. Sei. U.S.A. 89, 1529-1533 (1992).
11. Burke, P. A. et al. J. Exp. Med. 189, 1309-1321 (1989).
12. Israël, A. et al. EMBO J. 8, 3793-3800 (1989).
13. Baeuerle, P. A. & Baltimore, D. Science 242, 540-546 (1988).
14. Blank, V., Kourîlsky, P. & Israel, A. EMBO J. 10, 4159-167 (1991).
15. Beg, A. A. et al. Genes Dev. 8, 1899-1913 (1992).
16. Kidd, S. Cell 1, 623-635 (1992).
17. Fan, C.-M. & Maniatis, T. Nature 354, 395-398 (1991).
18. Kunsch, C., Ruben, S. M. & Rosen, C. A. Molec. cell. Biol. 12, 4412-1421 (1992).
19. Sodeoka, M., Larson, C. J., Chen, L, Lane, W. S. & Verdine, G. L. Biomed. Chem. Lett. 3, 1095-1100 (1993).
20. Baldwin, A. S. & Sharp, P. A. Molec. cell. Biol. 7, 305-313 (1987).
21. Ghosh, G., Van Duyne, G., Ghosh, S. & Sigler, P. B. Nature, 373, 303-310 (1995).
22. Cho, Y., Gorina, S., Jeffrey, P. D. & Pavletich, N. P. Science 235, 346-355 (1994).
23. Bork, P., Holm, L. & Sander, C. J. molec. Biol. 242, 309-320 (1994).
24. Juy, M. et al. Nature 357, 89-91 (1992).
25. Nekludova, L. & Pabo, C. O. Proc. natn. Acad. Sei. U.S.A. 91, 6948-6952 (1994).
26. Kumar, S., Rabson, A. B. & Gélinas, C. Molec. cell. Biol. 12, 3094-3106 (1992).
27. Seeman, N. C., Rosenberg, J. M. & Rich, A. Proc. natn. Acad. Sei. U.S.A. 73, 804-808 (1976).
28. Pavletich, N. P. & Pabo, C. O. Science 252, 809-817 (1991).
29. Ellenberger, T. E., Brandi, C. J., Struhi, K. & Harrison, S. C. Cell 71, 1223-1237 (1992).
30. Liu, J., Sodeoka, M., Lane, W. S. & Verdine, G. L. Proc. natn. Acad. Sei. U.S.A. 91, 908-912 (1994).
31. Glover, J. N. M. & Harrison, S. C. Nature 373, 257-261 (1995).
32. Liu, J., Fan, Q. R., Sodeoka, M., Lane, W. S. & Verdine, G. L. Chem. Biol. 1, 47-55 (1994).
33. Thanos, D. & Maniatis, T. Cell 71, 777-789 (1992).
34. Logeât, F. et al. EMBO J. 10, 1827-1832 (1991).
35. Lehming, N., McGuire, S., Brickman, J. M. & Ptashne, M. EMBO J. (submitted).
36. Carson, M. J. appl. Crystallogr. 24, 958-961 (1991).
37. Epp, O., Lattman, E. E., Schiffer, M., Huber, R. & Palm, W. Biochemistry 14, 4943-4952 (1975).
38. Leahy, D. M., Hendrickson, W. A., Aukhei, I. & Erickson, H. P. Science 258, 987-991 (1992).
39. Lavery, R. & Sklenar, H. J. Biomolec. Struct. Dynam. 8, 63-91 (1988).
40. Kraulis, P. J. J. appl. Crystallogr. 24, 946-950 (1991).
41. Hendrickson, W. A., Horton, J. R. & LeMaster, D. M. EMBO J. 9, 1665-1672 (1990).
42. Kabsch, W. J. appl. Crystallogr. 21, 916-924 (1988).
43. Hendrickson, W. A., Smith, J. L., Phizackeriey, R. P. & Merritt, E. A. Proteins: Structure, Function and Genetics 4, 77-88 (1988).
44. Ramakrishnan, V., Finch, J. T., Graziano, V., Lee, P. L. & Sweet, R. M. Nature 382, 219-223 (1993).
45. Bricogne, G. Acta crystallogr. A32, 832-847 (1976).
46. Jones, T. A., Zhou, J.-Y., Cowan, S. W. & Kjeldgaard, M. Acta crystallogr. A47, 110-119 (1991).
47. Brünger, A. T. X-PLOR Version 3.1.A System for X-ray Crystallography and NMR (Yale University Press, New Haven, CT, 1992).
48. Brünger, A. T. Nature 355, 472-75 (1992).