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Volumn 273, Issue 3, 1995, Pages 273-279

The selective 5-HT2A receptor antagonist, MDL 100,907, increases dopamine efflux in the prefrontal cortex of the rat

Author keywords

5 HT2 receptor; Antipsychotic; Clozapine; Microdialysis; Prefrontal cortex

Indexed keywords

3,4 DIHYDROXYPHENYLACETIC ACID; ALPHA (2,3 DIMETHOXYPHENYL) 1 [2 (4 FLUOROPHENYL)ETHYL] 4 PIPERIDINEMETHANOL; DOPAMINE; FLUOROBENZENE; HOMOVANILLIC ACID; PIPERIDINE DERIVATIVE; RITANSERIN; SEROTONIN ANTAGONIST; CLOZAPINE; NEUROLEPTIC AGENT; SEROTONIN 2A ANTAGONIST; SEROTONIN 2A RECEPTOR;

EID: 0028978933     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(94)00698-7     Document Type: Article
Times cited : (118)

References (44)
  • 4
    • 0026611392 scopus 로고
    • The regulation of subcortical dopamine systems by the prefrontal cortex: interaction of central dopamine systems and the pathogenesis of schizophrenia
    • (1992) J. Neural Transm. , vol.36 , pp. 61
    • Deutch1
  • 5
    • 0025286232 scopus 로고
    • Prefrontal cortical dopamine depletion enhances the responsiveness of mesolimbic dopamine neurons to stress
    • (1990) Brain Res. , vol.521 , pp. 311
    • Deutch1    Clark2    Roth3
  • 8
    • 0023753615 scopus 로고
    • Burst firing induced in mid-brain dopamine neurons by stimulation of the median prefrontal and anterior cingulate cortices
    • (1988) Brain Res. , vol.462 , pp. 194
    • Gariano1    Groves2
  • 13
    • 0025782434 scopus 로고
    • Microinjection of apomorphine into the prefrontal cortex of the rat reduces dopamine metabolite concentrations in microdialysate from the caudate nucleus
    • (1991) Biol. Psychiatry , vol.29 , pp. 703
    • Jaskiw1    Weinberger2    Crawley3
  • 16
    • 0023616461 scopus 로고
    • Lesions of the dopamine neurons in the median prefrontal cortex: effects on self-administration of amphetamine and dopamine synthesis in the brain of the rat
    • (1987) Neuropharmacology , vol.26 , pp. 1303
    • Leccese1    Lyness2
  • 21
    • 0024468417 scopus 로고
    • Clinical studies on the mechanism of action of clozapine: the dopamine-serotonin hypothesis of schizophrenia
    • (1989) Psychopharmacology , vol.99 , pp. S18
    • Meltzer1
  • 22
    • 0026602565 scopus 로고
    • The importance of serotonin-dopamine interactions in the action of clozapine
    • (1992) Br. J. Psychiatry , vol.160 , pp. 22
    • Meltzer1
  • 24
    • 0025239750 scopus 로고
    • Acute effects of typical and atypical antipsychotic drugs on the release of dopamine from prefrontal cortex, nucleus accumbens and straitum of the rat: an in vivo microdialysis study
    • (1990) J. Neurochem. , vol.54 , pp. 1755
    • Moghaddam1    Bunney2
  • 32
    • 0019190758 scopus 로고
    • Effect of lesion of cortical dopamine terminals on subcortical dopamine receptors in rats
    • (1980) Nature , vol.286 , pp. 74
    • Pycock1    Kerwin2    Carter3
  • 34
    • 0026763542 scopus 로고
    • Effects of 6-hydroxydopamine lesions of the prefrontal cortex on tyrosine hydroxylase activity in mesolimbic and nigrostriatal dopamine systems
    • (1992) Neuroscience , vol.48 , pp. 831
    • Rosin1    Clark2    Goldstein3    Roth4    Deutch5
  • 36
    • 0027233386 scopus 로고
    • In vivo release of dopamine from rat stratum, substantia nigra and prefrontal cortex: differential modulation by baclofen
    • (1993) Br. J. Pharmacol. , vol.109 , pp. 814
    • Santiago1    Machado2    Cano3
  • 37
    • 0026613672 scopus 로고
    • 2 receptors exert a state-dependent regulation of dopaminergic function: studies with MDL 100,907 and the amphetamine analogue, 3,4-methylenedioxy-methamphetamine
    • (1992) Eur. J. Pharmacol. , vol.223 , pp. 65
    • Schmidt1    Fadayel2    Sullivan3    Taylor4
  • 39
    • 0026638085 scopus 로고
    • Prefrontal cortical efferents in the rat synapse on unlabeled neuronal targets of catecholaminergic terminals in the nucleus accumbens septi and on dopamine neurons in the ventral tegmental area
    • (1992) J. Comp. Neurol. , vol.320 , pp. 145
    • Sesack1    Pickel2
  • 42
    • 0025010158 scopus 로고
    • A review of clozapine: an antipsychotic for treatment-resistant schizophrenia
    • (1990) Compr. Psychiatry , vol.31 , pp. 315
    • Stephens1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.