Postsynaptic injection of Ca2+/CaM induces synaptic potentiation requiring CaMKII and PKC activity

Neuron

Volumn 15, Issue 2, 1995, Pages 443-452

  Wang, Jin Hui ^a   Kelly, Paul T ^a  

^a UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BICUCULLINE; CALCIUM; CALMODULIN; CALMODULIN BINDING PROTEIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DERIVATIVE; PHACLOFEN; PICROTOXIN; PROTEIN KINASE (CALCIUM,CALMODULIN) II; PROTEIN KINASE C; PROTEIN KINASE INHIBITOR; CA(2+) CALMODULIN DEPENDENT PROTEIN KINASE; CALMODULIN BINDING PROTEINS; CALMODULIN DEPENDENT PROTEIN KINASE II; CALMODULIN-DEPENDENT PROTEIN KINASE II; CYCLIC AMP DEPENDENT PROTEIN KINASES; NERVE PROTEIN; NEUROGRANIN; PEPTIDE FRAGMENT; PROTEIN KINASE (CALCIUM,CALMODULIN);

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SUBSTRATE; EXCITATORY POSTSYNAPTIC POTENTIAL; HIPPOCAMPUS; LONG TERM POTENTIATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; AMINO ACID SEQUENCE; ANIMAL; CELL MEMBRANE POTENTIAL; DRUG EFFECT; ELECTROSTIMULATION; MOLECULAR GENETICS; PATCH CLAMP; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN PROCESSING; RAT STRAIN; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMAL; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CALCIUM; CALMODULIN; CALMODULIN-BINDING PROTEINS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ELECTRIC STIMULATION; LONG-TERM POTENTIATION; MALE; MEMBRANE POTENTIALS; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; PATCH-CLAMP TECHNIQUES; PEPTIDE FRAGMENTS; PHOSPHORYLATION; PROTEIN KINASE C; PROTEIN PROCESSING, POST-TRANSLATIONAL; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0028978444     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/0896-6273(95)90048-9     Document Type: Article

References (72)

1. Modified hippocampal long-term potentiation in PKCy-mutant mice
2. Translocation of protein kinase C activity may mediate hippocampal long-term potentiation
3. Regulation of calmodulin binding to P-57
4. Calcium waves
5. Calcium and calmodulin function in the cell nucleus
6. A synaptic model of memory: LTP in the hippocampus
7. Long-term potentiation of synaptic transmission in the hippocampus: properties and mechanisms
8. Long-term potentiation in hippocampal CA3 neurons: tetanized input regulates heterosynaptic efficacy
9. Activators or PKC increase the phosphorylation of the synapsins on sites phosphorylated by PKA and CaM-kinase II in rat hippocampal slice
10. Diverse sources of hippocampal unitary inhibitory postsynaptic potentials and the number of synaptic release sites
11. Intracellular calcium homeostasis
12. Studies with synthetic peptide substrates derived from the neuronal protein neurogranin reveal structural determinants of potency and selectivity for protein kinase C
13. The regulatory diversity of the mammalian adenylyl cyclases
14. NMDA receptors: their role in long-term potentiation
15. Probing the cyclic nucleotide binding sites of CAMP-dependent protein kinases I and II with analogs of adenosine 3′5′-cyclic phosphorothioates
16. PKC(19–31) and CaMKII(273–302) given together intracellularly to the postsynaptic neuron synergistically block LTP in hippocampal CA1 region
17. Autophosphorylation of protein kinase C at three separate regions of its primary sequence
18. Effects of cAMP stimulate a late stage of LTP in hippocampal CA1 neurons
19. 2+/cal-modulin-dependent protein kinase II
20. Primary structural determinants essential for potent inhibition of cAMP-dependent protein kinase by inhibitory peptides corresponding to the active portion of the heat-stable inhibitor protein
21. Impaired LTP, spatial learning and hippocampal development in fyn mutant mice
22. Phorbol esterinduced synaptic potentiation differs from long-term potentiation in the guinea pig hippocampus in vitro
23. Physiological mechanisms underlying long-term potentiation
24. Mapping of calmodulin-binding domain of Cal`/calmodulin-dependent protein kinase II from rat brain
25. Dual role of calmodulin in autophosphorylation of multifunctional CaM kinase may underlie decoding of calcium signals
26. Protein kinase C contains a pseudosubstrate prototype in its regulatory domain
27. PKC injected into hippocampal pyramidal cells elicits features of long term potentiation
28. Specificity of protein kinase inhibitor peptides and induction of long-term potentiation
29. A persistent postsynaptic modification mediates long-term potentiation in the hippocampus
30. Functional Analysis of the calmodulin (CaM)binding domain of CaMKinase If (CK-II) using synthetic peptides and site-directed mutagenesis
31. Mechanism of protein kinase C activation during the induction and maintenance of long-term potentiation probed using selective peptide substrate
32. Concerted regulation of protein phosphorylation and dephosphorylation by calmodulin
33. The CaM kinase II hypothesis for the storage of synaptic memory
34. 2+/calmodulin-dependent protein kinase molecules of the postsynaptic density
35. Calciumcalmodulin modulation of olfactory cyclic nucleotide-gated cation channel
36. Stimulusinduced coordinate changes in mRNA abundance in single postsynaptic hippocampal CA1 neurons
37. 2+/calmodulin-dependent protein kinase
38. Mechanisms underlying long-term potentiation of synaptic transmission
39. NMDA-receptor-dependent synaptic plasticity: multiple forms and mechanisms
40. Phorbol esters mimic some cholinergic actions in hippocampal pyramidal neurons
41. Postsynaptic calcium is sufficient for potentiation of hippocampal synaptic transmission
42. An essential role for postsynaptic calmodulin and protein kinase activity in long-term potentiation
43. Temporal limits on the rise in postsynaptic calcium required for the induction of long-term potentiation
44. Inhibition of postsynaptic PKC or CaMKII blocks induction but not expression of LTP
45. Protein kinase A inhibitors prevent the maintenance of hippocampal long-term potentiation
46. 2+-binding proteins from bovine brain including a potent inhibitor of protein kinase C
47. Phosphorylation and regulation of glutamate receptors by calcium/calmodulin-dependent protein kinase II
48. 2+-triggered molecular switch
49. Phorbol ester-induced synaptic facilitation is different than long-term potentiation
50. 2+ responses
51. 2+/calmodulin-dependent kinase in intact hippocampal slices
52. Long-term potentiation in the hippocampus is blocked by tyrosine kinase inhibitors
53. The role of Cal' entry via synaptically activated NMDA receptors in the induction of long-term potentiation
54. Potentiated transmission and prevention of further LTP by increased CaMKII activity in postsynaptic hippocampal slice neuron
55. Calmodulin, cell growth and gene expression
56. Optical imaging of calcium accumulation in hippocampal pyramidal cells during synaptic activation
57. Postsynaptic NMDA receptormediated calcium accumulation in hippocampal CA1 pyramidal cell dendrites
58. Persistent activation of the isoform of protein kinase C in the maintenance of long-term potentiation
59. Protein kinase C in human brain and its inhibition by calmodulin
60. 2+/calmodulin-dependent protein kinase produces an autonomous enzyme in Aplysia neurons
61. Inhibitory CAI-CA3-hilar region feedback in the hippocampus
62. Deficient hippocampal long-term potentiation in a-calcium-calmodulin kinase 11 mutant mice
63. Phosphorylation of AMPA-type glutamate receptors by calcium/calmodulindependent protein kinase II and protein kinase C in cultured hippocampal neurons
64. Spatial and temporal changes in signal transduction pathways during LTP
65. Electrotonic profiles of interneurons in stratum pyramidale of the CA1 region of rat hippocampus
66. Calcium channels, stores, and oscillation
67. Postsynaptic protein kinase C essential to induction and maintenance of long-term potentiation in the hippocampal CA1 region
68. Modulation of AMPA/kainate receptors in cultured murine hippocampal neurones by protein kinase C
69. 2+/calmodulin-dependent protein kinase II is phosphorylated by protein kinase C in vitro
70. Altered behavior and long-term potentiation in type 1 adenylyl cyclase mutant mice
71. Role of guanylyl cyclase and cGMP-dependent protein kinase in long-term potentiation