Diminished [3H]inositol(1,4,5)P3 but not [3H]inositol(1,3,4,5)P4 binding in Alzheimer's disease brain

Brain Research

Volumn 681, Issue 1-2, 1995, Pages 160-166

  Garlind, Anita ^a   Cowburn, Richard F ^a   Forsell, Charlotte ^a   Ravid, Rivka ^c   Winblad, Bengt ^a   Fowler, Christopher J ^a,b  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b ASTRAZENECA R AND D   (Sweden)

^c NETHERLANDS INSTITUTE FOR NEUROSCIENCE   (Netherlands)

Author keywords

Alzheimer's disease; Calcium; Inositol(1,3,4,5)P4; Inositol(1,4,5)P3; Phosphatidylinositol hydrolysis; Receptor; Signal transduction

Indexed keywords

INOSITOL 1,3,4,5 TETRATRIPHOSPHATE; INOSITOL 1,4,5 TRISPHOSPHATE; UNCLASSIFIED DRUG; CALCIUM CHANNEL; CELL RECEPTOR; INOSITOL 1,3,4,5 TETRAKISPHOSPHATE; INOSITOL 1,3,4,5 TETRAKISPHOSPHATE RECEPTOR; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; INOSITOL PHOSPHATE; INOSITOL-1,3,4,5-TETRAKISPHOSPHATE; INOSITOL-1,3,4,5-TETRAKISPHOSPHATE RECEPTOR; ITPR1 PROTEIN, HUMAN; LIGAND; NERVE PROTEIN;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; BINDING SITE; BRAIN TISSUE; CALCIUM TRANSPORT; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; MALE; PRIORITY JOURNAL; BRAIN LEVEL; COMPARATIVE STUDY; IN VITRO STUDY; KINETICS; METABOLISM; MIDDLE AGED; PHYSIOLOGY;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; BRAIN CHEMISTRY; CALCIUM CHANNELS; FEMALE; HUMANS; INOSITOL 1,4,5-TRISPHOSPHATE; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; INOSITOL PHOSPHATES; KINETICS; LIGANDS; MALE; MIDDLE AGED; NERVE TISSUE PROTEINS; RECEPTORS, CYTOPLASMIC AND NUCLEAR;

EID: 0028978364     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(95)00311-D     Document Type: Article

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