Bradykinin-induced vasodilation is changed to a vasoconstrictor response in vessels of aged normotensive and hypertensive rats

Inflammation Research

Volumn 44, Issue 2, 1995, Pages 70-73

  Mantelli, Laura ^a   Amerini, Sandra ^a   Ledda, Fabrizio ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Aging; Bradykinin; Mesenteric vascular bed; Spontaneously hypertensive rats (SHR)

Indexed keywords

BRADYKININ; BRADYKININ ANTAGONIST; BRADYKININ B1 RECEPTOR; BRADYKININ B2 RECEPTOR; INDOMETACIN; METHOXAMINE; PROSTANOID;

AGING; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; HYPERTENSION; MESENTERY BLOOD FLOW; NONHUMAN; RAT; VASCULAR ENDOTHELIUM; VASOCONSTRICTION; VASODILATATION;

AGING; ANIMAL; BRADYKININ; COMPARATIVE STUDY; DISEASE MODELS, ANIMAL; ENDOTHELIUM, VASCULAR; HYPERTENSION; MESENTERIC ARTERIES; METHOXAMINE; MUSCLE CONTRACTION; MUSCLE RELAXATION; MUSCLE, SMOOTH, VASCULAR; RATS; RATS, INBRED SHR; RATS, INBRED WKY; SUPPORT, NON-U.S. GOV'T; VASOCONSTRICTION; VASODILATION;

EID: 0028969839     PISSN: 10233830     EISSN: 1420908X     Source Type: Journal    
DOI: 10.1007/BF01793215     Document Type: Article

References (20)

1. The effects of kinins on the cardiovascular system
2. Pharmacology of bradykinin and related kinins
3. Actions of bradykinin on isolated cerebral and peripheral arteries
4. The role of endothelial and non-endothelial prostaglandins in the relaxation of isolated blood vessels of the rabbit induced by acetylcholine and bradykinin
5. Bradykinin suppresses endothelininduced contraction of coronary, renal and femoral arteries through its B2-receptor on the endothelium
6. Characterization of endotheliumdependent relaxations resistant to nitro-L-arginine in the porcine coronary artery
7. Mechanism of contractile responses to bradykinin in canine basilar arteries
8. Vascular mode of action of kinin-B1 receptors and development of a cellular model for the investigation of these receptors
9. Bradykinininduced vasoconstriction of rat mesenteric arteries precontracted with noradrenaline
10. Endothelial cell loss enhances the pressor response in resistance vessels
11. Bradykinin-induced mesenteric vasodilation is mediated by B2-subtype receptors and nitric oxide
12. Inhibitory effects of Hoe 140 on vasodilator responses to bradykinin in the mesenteric vascular bed of the cat
13. Effects of bradykinin in the rat isolated perfused heart: role of kinin receptors and endothelium-derived relaxing factor
14. Studies on the induction of pharmacological responses to des-Arg9-bradykinin in vitro and in vivo
15. De novo formation of vascular receptor for bradykinin
16. Induction of the B1-receptors for kinins in the rabbit by bacterial lipopolysaccharide
17. B1 and B2 kinin receptors on cultured rabbit superior mesenteric artery smooth muscle cells: receptor-specific stimulation of inositol phosphate formation and arachidonic acid release by Des-Arg9-bradykinin and bradykinin
18. Bradykinin: potential for vascular constriction in the presence of endothelial injury