Seronegative chronic relapsing neuroborreliosis

European Neurology

Volumn 35, Issue 2, 1995, Pages 113-117

  Lawrence, Christine ^a   Lipton, Richard B ^a   Lowy, Franklin D ^a   Coyle, P K ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

Herxheimer; Immune complex; Lyme disease, Seronegative

Indexed keywords

ANTIBIOTIC AGENT; ANTIBODY; BACTERIAL ANTIGEN; CEFOTAXIME; CEFTRIAXONE; CLARITHROMYCIN; DOXYCYCLINE; IBUPROFEN; METHYLPREDNISOLONE SODIUM SUCCINATE; NUCLEIC ACID; PREDNISONE;

ADULT; AGRANULOCYTOSIS; ANTIBODY DETECTION; ANTIGEN ANTIBODY COMPLEX; ARTHRALGIA; ARTICLE; BORRELIA INFECTION; CASE REPORT; CEREBROSPINAL FLUID ANALYSIS; CHILL; FEMALE; FEVER; HERXHEIMER REACTION; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; LYME DISEASE; NEUROLOGIC DISEASE; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RECURRENT DISEASE;

ANTIBIOTICS; ANTIBODIES, BACTERIAL; ANTIGEN-ANTIBODY REACTIONS; CASE REPORT; CHRONIC DISEASE; FEMALE; HUMAN; LYME DISEASE; MIDDLE AGE; NERVOUS SYSTEM DISEASES; RECURRENCE;

EID: 0028968975     PISSN: 00143022     EISSN: 14219913     Source Type: Journal    
DOI: 10.1159/000117104     Document Type: Article

References (22)

1. Dattwyler RJ., Volkman DJ, Luft BJ, Halperin JJ, Thomas J, Golightlv MG: Seronegative Lyme disease: Dissociation of the specific T- and B-lymphocyte responses to Borrelia burg- dorferi. N Engl j Med 1988;319:1441-1446.
2. Halperin JJ, Volkman DJ., Wu P: Central nervous system abnormalities in Lyme neurobor- reliosis. Neurology 1991:41:1571-1582.
3. Keller TL., Halperin JJ, Whitman M: PCR detection of Borrelia burgdorferi DNA in cerebrospinal fluid of Lyme neuroborreliosis patients. Neurology 1992;42:32-42.
4. Luft BJ., Steinman CR., Neimark HC., Muralid- har B., Rush T, Finkel MF., Kunkel M., Dattwyler RJ: Invasion of the central nervous system by Borrelia burgdorferi in acute disseminated infection. JAMA 1992;267:1364-1367.
5. Marconi RT, Lubke L, Hauglum W, Garon CF: Species-specific identification and distinction between Borrelia burgdorferi genomic groups by using 16S rRNA-directed oligonucleotide probes. J Clin Microbiol 1992;30:628-632.
6. Coyle PK., Schützer SE., Belman AL, Krupp LB, Golightly MG: Cerebrospinal fluid immune complexes in patients exposed to Borrelia burg-dorferi: Detection of Borrelia-specific and -nonspecific complexes. Ann Neurol 1990;28: 6:739-744.
7. Coyle PK, Deng Z, Schützer SE, Belman AL, Benach J, Krupp LB, Luft B: Detection of Borrelia burgdorferi antigens in cerebrospinal fluid. Neurology 1993;43:1093-1097.
8. Steere AC, Dwyer E, Winchester R: Association of chronic lyme arthritis with HLA-DR4 and HLA-DR2 alleles. N Engl J Med 1990;323: 212-223.
9. Bryceson AD: Clinical pathology of the Jarish Hcrkheimer reaction. J Infect Dis 1976,133: 696-705.
10. Dressier F, Yoshinari NH, Steere AC: The T- ccll proliferation assay in the diagnosis of Lyme disease. Ann Intern Med 1991;115:533-539.
11. Hardin JA., Steere AC, Malawista SE: Immune complexes and the evolution of lyme arthritis: Dissemination and localization of abnormal C1 q binding activity. N Engl J Med 1979:301: 1358-1363.
12. Hassler D., Riedel K, Zorn J, Preac-Mursic V: Pulsed high-dose cefotaxime therapy in refractory Lyme borreliosis (letter). Lancet 1991;338: 193.
13. Logigian EL, Kaplan RF, Steere AC: Chronic neurologic manifestations of Lyme disease. N Engl J Med 1990;323:1438-1444.
14. Benach JL, Fleit HB, Habicht GS., Coleman JL, Bosler EM, Lane BP: Interactions of phagocytes with the Lyme disease spirochete: Role of the Fc receptor. J Infect Dis 1984; 150:497-507.
15. Hansen K, Lebech A-M: The clinical and epi-demiological profile of Lyme neuroborreliosis in Denmark 1985-1990. Brain 1992:115:399-423.
16. Ackermann R, Rehse-Kiipper B, Gollmer E., Schmidt R: Chronic neurologic manifestations of erythema migrans borreliosis. Ann NY Acad Sei 1988:539:16-23.
17. Stanek G, Pletschette M., Flamm H, Hirschl AM., Aberer E, Kristoferitsch W, Schmutzhard E: European Lyme borreliosis. Ann NY Acad Sei 1988:539:274-282.
18. Ishiguro M, Koga H, Kohno S, Hayashi T, Yamaguchi K, Hiroka M: Penetration of mac- rolides into human polymorphonuclear leucocytes. J Antimicrob Chemother 1989:24:719-729.
19. Montgomery RR, Nathanson MH, Malawista SE: The fate of Borrelia burgdorferi in mouse macrophages: Destruction, survival, recovery (abstr. 143), 5th Int Conf Lyme Borreliosis, Arlington, Va., 1992. p A25.
20. Mahmoud AAF: The challenge of intracellular pathogens (editorial). N Engl J Med 1992:326: 761-762.
21. Pachner AR., Itano AB., burgdorferi infection of the brain. Neurology 1990;40:1535-1540.
22. Licgner KB., Rosenkilde GE., Campbell GL, Quan TJ, Dennis DT: Culture-confirmed treatment failure of cefotaxine and minocycline in a case of Lyme meningoencephalomyelitis in the United States (abstr. 63) 5th Int Conf Lyme Borreliosis, Arlington, Va., 1992, p 11.