Stimulation of the human cytomegalovirus IE enhancer/promoter in HL-60 cells by TNFα is mediated via induction of NF-κB

Virology

Volumn 208, Issue 1, 1995, Pages 197-206

  Prösch, Susanna ^a   Staak, Kerstin ^a   Stein, Joachim ^a   Liebenthal, Christa ^a   Stamminger, Thomas ^b   Volk, Hans Dieter ^a   Krüger, Detlev H ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0028968138     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1995.1143     Document Type: Article

References (64)

1. Abken, H., and Reifenrath, B. (1992). A procedure to standardize CAT reporter gene assay. Nucleic Acids Res. 20, 3527.
2. Baeuerle, P. A. (1991). The inducible transcription factor NF-kB: Régulation by distinct protein subunits, Biochim. Biophys. Acta 1072, 63-80.
3. Baeuerle, P. A., and Baltimore, D. (1988a). Activation of DNA binding in an apparently cytoplasmic precursor of the NF-kB transcription factor. Cell 53, 211-217.
4. Baeuerle, P. A., and Baltimore, D. (1988b), IkB: A specific inhibitor of the NF-kB transcription factor. Science 242, 540-546.
5. Beg, A. A., Finco, T. S., Nantermet, P. V., and Baldwin, A. S. (1993). Tumor necrosis factor and interleukin-lead to phosphorylation and loss of IkBa; A mechanism for NF-kB activation. Mol. Cell. Biol. 13, 3301-3310.
6. Bitsch, A., Kirchner, H., Dupke, R., and Bein, G. (1993). Cytomegalovirus transcripts in peripheral blood leukocytes of actively infected transplant patients detected by reverse transcription-polymerase chain reaction. J. Infect. Dis. 167, 740-743.
7. Boshart, M., Weber, F., Jahn, G., Dorsch-Hasler, K., Fleckenstein, B., and Schaffner, W. (1985). Avery strong enhancer is located upstream of an immediate early gene of human cytomegalovirus. Cell 41, 521-530.
8. Bradford, M. M. (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding. Anaiyt. Biochem. 72, 248-254.
9. Dbaibo, G. S., Obeid, L M., and Hannun, Y. A. (1993). Tumor necrosis factor;A (TNF-a) signal transduction through ceramide. J. Biol. Chem. 268, 17762-17766.
10. Döcke, W. D., Prösch, S., Fietze, E., Kimel, V., Zuckermann, H., Kluge, C., Syrbe, U., Kruger, D. H., von Baehr, R., and Volk, H. D. (1994). Cytomegalovirus reactivation and tumour necrosis factor. Lancet 343, 268-269.
11. Dressier, K. A., Mathias, S., and Kolesnick, R. N. (1992). Tumor necrosis factor-a activates the sphingomyelin signal transduction pathway in a cell-free system. Science 255, 1715-1718.
12. Duh, E. J., Mavry, W. J., Folks, T. M., Fauci, A. S., and Rabson, A. B. (1993). Tumor necrosis factor alpha activates human immunodeficiency virus type 1 through induction of nuclear factor binding to the NF-kB sites in the long terminal repeat. Proc. Natl. Acad. Sci. USA 86, 5974-5978.
13. Fickenscher, H., Stamminger, T, Rüger, R., and Fleckenstein, B. (1989). The role of a repetitive palindromic sequence element in the human cytomegalovirus major immediate early enhancer. J. Gen. Virol. 70, 107-123.
14. Fietze, E., Prösch, S., Reinke, P., Stein, J., Döcke, W. D., Staffa, G., Loening, S., Emmrich, F., von Baehr, R., Krüger, D. H., anti Volk, H. D. (1994). Cytomegalovirus infection in transplant recipients: Role of tumor necrosis factor. Transplantation 58, 675-680.
15. Ghosh, S., and Baltimore, D. (1990). Activation in vitro of NF-kB by phosphorylation of its inhibitor IkB. Nature (London) 334, 678-682.
16. Griffin, G. E., Leung, K., Folks, T. M., Kunkel, S., and Nabel, G. J. (1991). Induction of NF-kB during monocyte differentiation is associated with activation of HIV-gene expression. Res. Virol. 142, 233-238.
17. Haagmans, B. L, Stals, F. S., van der Meide, P. H., Bruggeman, C. A., Horzinek, M. C., and Schijns, V. E. C. J. (1994). Tumor necrosis factor alpha promotes replication and pathogenicity of rat cytomegalovirus. J. Virol. 68, 2297-2304.
18. Hamanaka, R., Kohno, K., Seguchi, T., Okamura, K., Morimoto, A., Ono, M., Ogata, J., and Kuwano, M. (1992). Induction of low density lipoprotein receptor and a transcription factor SP-1 by tumor necrosis factor in human microvascular endothelial cells. J. Biol. Chem. 267, 13160-13165.
19. Henkel, T, Machleidt, T., Alkalay, I., Krönke, M., Ben-Nerah, Y., and Baeuerle, P. A, (1993). Rapid proteolysis of IkB-a is necessary for activation of transcription factor NF-kB. Nature (London) 365, 182-185.
20. Hersh, E. M., Brewton, G., Abrams, D., Bartlett, J., Galpin, J., Parkash, G., Gorter, R., Gottlieb, M., Jonikas, J. J., Landesman, S., Levine, A., Marcel, A, Petersen, E. A., Whiteside, M., Zahradnik, J., Negron, C., Boutitie, F., Caraux, J., Dupuy J. M., and Salmi, L. F. (1991). Dithiocarb sodium (diethylcarbamate) therapy in patients with symptomatic HIV infection and AIDS. JAMA 265, 1538-1544.
21. Hidaka, H., Inagaki, M., Kawamoto, S., and Sasaki, Y. (1984). Isoquinol-inesulfonamides, novel an potent inhibitors of cyclic nucleotide dependent protein kinase and protein kinase C. Biochemistry 23, 5036-5041.
22. Hunninghake, G. W., Monick, M. M., Lin, B., and Slinski, M. (1989). The promoter-regulatory region of the major immediate-early gene of human cytomegalovirus responds to T-lymphocyte stimulation and contains functional cyclic AMP-response elements. J. Virol. 63, 3026-3033.
23. Kim, M. J., Linardic, C., Obeid, L, and Hannun, Y. (1991). Identification of sphingomyelin turnover as an effector mechanism for the action of tumor necrosis factor a and g-interferon. J. Biol. Chem. 266, 484-489.
24. Kothari, S., Baillie, J., Sissons, J. G. P., and Sinclair, J. H. (1991). The 21 bp repeat element of the human cytomegalovirus major immediate early enhancer is a negative regulator of gene expression in undifferentiated ceils. Nucleic Acids Res. 19, 1767-1771.
25. Lang, D., and Stamminger, T. (1991). Binding of transcription factor SP1 to the IE-1 promoter region of human cytomegalovirus. (M. P. Landini, Ed.). Exerpta Med. 1991.
26. Lenardo, M. J., and Baltimore, D. (1989), NF-kB: A pleiotropic mediator of inducible and tissue-specific gene control. Cell 58, 227-229.
27. Lowenthal, J. W., Ballard, D. W., Bogerd, H., Böhnlein, E., and Greene, W. C. (1989). Tumor necrosis factor a activation of the IL-2 receptor-alpha gene involves the induction of kappa B-specific DNA binding proteins. J. Immunol. 142, 3121-3128.
28. Maciejewski, J. P., Bruening, E. E., Donahue, R. E., Mocarskt, E., Young, N. S., and St Yeor, S. (1992). Infection of hematopoitic progenitor cells by human cytomegalovirus. Blood 80, 170-178.
29. Mellors, J. W., Griffith, B. P., Oritz, M. A., Landry, M. L, and Ryan, J. L. (1991). Tumor necrosis factor a/cachectin enhances human immunodeficiency virus type 1 replication in primary macrophages. J. infect. Dis. 163, 78-82.
30. Meichle, A., Schütze, S., Hensel, G., Brunsig, D., and Krönke, M. (1990). Protein kinase C -Independent activation of nuclear factor kB by tumor necrosis factor. J. Biol. Chem. 265, 8339-8343.
31. Moch, H., Lang, D., and Stamminger, T. (1992). Strong trans activation of the human cytomegalovirus major immediate-early enhancer by p40ta* of human T-cell leukemia virus type i via two repetitive tax-responsive sequence elements. J. Virol. 66, 7346-7354.
32. Montminy, M. R., Sevarino, K. A., Wagner, J. A., Mandel, G., and Goodman, R. H. (1986). Identification of a cyclic AMP-responsive element within the rat somatostatin gene. Proc. Natl. Acad. Sci. USA 83, 6682-6686.
33. Niller, H. H., and Hennighausen, L (1991). Formation of several specific nucleoprotein complexes on the human cytomegalovirus immediate early enhancer. Nucleic Acids Res. 19, 3715-3721.
34. Osborn, L, Kunkel, S., and Nabel, G. J. (1989). Tumor necrosis factor a and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor kB. Proc. Natl. Acad. Sci. USA 86, 2336-2340.
35. Paya, C. V., Virelizier, I. L, and Michelson, S. (1991). Modulation of T-cell activation through protein kinase-C or A-dependent signalling pathways synergisticaSly increases human immunodeficiency virus long terminal repeat induction by cytomegalovirus immediate-early proteins. J. Virol. 65, 5477-5484.
36. Poli, G., Kinter, A., Justement, J. S., Kehrl, J. H., Bressler, P., Stanley, S., and Fauci, A. S. (1990). Tumor necrosis factor alpha functions in anautocrine manner in the induction of human immunodeficiency virus expression. Proc. Natl. Acad. Sci. USA 87, 782-785.
37. Quick, J., Ware, J. A., and Driedger, P. E. (1992). The structure and biological activities of the widely used protein kinase inhibitor, H7, differ depending on the commercial source. Biochem. Biophys. Res. Commun. 187, 657-663.
38. Reisinger, E. C., Kern, P., Ernst, M., Bock, P., Flad, H. D., Dietrich, M., and German DTC Study Group. (1990). inhibition of HIV progression by dithiocarb. Lancet 335, 679-682.
39. Ruben, S. M., Dillon, P. J., Schreck, R., Henkel, T., Chen, C. H., Maher, M., Baeuerle, P. A., and Rosen, C. A. (1991). Cellular transcription factors and regulation of IL-2 receptor gene expression by HTLV-I Tax gene product. Science 241, 89-92.
40. Rubin, R. H. (1990). Impact of cytomegalovirus infection on organ transplant recipients. Rev. Infect. Dis. 12, S754-S766.
41. Sambucetti, L. C., Cherrington, J. M., Wilkinson, G. W. G., and Mocarski, E. S. (1989). NF-kB activation of the cytomegalovirus enhancer is mediated by a viral transactivator and by T cell stimulation. EMBO J. 8, 4251-4258.
42. Schächtele, C., Seifert, R., and Osswald, H. (1988). Stimulus dependent inhibition of platelat aggregation by the protein kinase C inhibitors polymyxin B, H7 and Stauroporine. Biochem. Biophys. Res. Commun. 151, 542-547.
43. Scheurich, P., Körbich, G., and Pfizenmaier, K. (1989). Antagonistic control of tumor necrosis factor receptors by protein kinases A and C. Enhancement of TNF receptor synthesis by protein kinase A and transmodulation of receptors by protein kinase C. J. Exp. Med. 170, 947-957.
44. Schreck, R., and Baeuerle, P. A. (1991). A rote of oxygen radicals as second messengers. Trends Cell. Biol. 1, 39-42.
45. Schreck, R., Grassmann, R., Fleckenstein, B., and Baeuerle, P. A. (1992a). Antioxidants selectively suppress activation of NF-kB by human T-cell leukemia virus type I tax protein. J. Virol. 66, 6288-6293.
46. Schreck, R., Meier, B., Männel, D. N., Dröge, W., and Baeuerle, P. A. (1992b). Dithiocarbamatcs as potent inhibitors of nuclear factor k8 activation in intact cells. J. Exp. Med. 175, 1181-1194.
47. Schrier, R. D., Nelson, J. A., and Oldstone, M. B. (1985). Detection of human cytomegalovirus in peripheral blood lymphocytes in a natural infection. Science 230, 1048-1051.
48. Schütze, S., Potthoff, K., Machleidt, T., Berkovic, D., Wiegmann, K., and Krönke, M. (1992). TNF activates NF-kB by phosphatidylcholine-specific phospholipase C-induced "acidic’' sphingomyelin breakdown. Ceil 71, 765-776.
49. Sen, R., and Baltimore, D. (1986). Inducibility of kappa immunoglobulin enhancer-binding protein NF-kB by a posttranslational mechanism. Cell 47, 921-928.
50. Shelborn, S. L, Kothari, S. K., Sissons, J. G. P., and Sinclair, J. H. (1989). Repression of human cytomegalovirus gene expression associated with a novel immediate early regulatory region binding factor. Nucleic Acids Res. 17, 9165-9171.
51. Siddiqui, A., Gaynor, R., Srinivasan, A., Mapoles, J., and Farr, R. W. (1989). Trans-activation of viral enhancers including long terminal repeat of the human immunodeficiency virus by the hepatitis B virus X protein. Virology 169, 479-484.
52. Sinclair, J. H., Baiilie, J., Bryant, L. A., Taylor-Wiedeman, J. A., and Sissons, J. G, P. (1992). Repression of human cytomegalovirus major immediate early gene expression in a monocytic cell line. J. Gen. Virot. 73, 433-435.
53. Söderberg, C., Larssor, S., Bergstedt-Lindqvist, S., and Möller, E. (1993). Definition of a subset of human peripheral blood mononuclear cells that are permissive to human cytomegalovirus infection. J. Virol. 67, 3166-3175.
54. Stamminger, T., and Fleckenstein, B. (1990). Immediate-early transcription regulation of human cytomegalovirus. Curr. Top. Microbiol. Immunol. 154, 3-19.
55. Stamminger, T., Fickenscher, H., and Fleckenstein, B. (1990). The cell type-specific induction of the major immediate early enhancer of human cytomegalovirus by cyclic AMP. J. Gen. Virol. 71, 105-113.
56. Stein, J., Volk, H. D., Liebenthal, Ch., Kruger, D. H., and Prösch, S. (1993). Tumor necrosis factor alpha stimulates the activity of the human cytomegalovirus major immediate early enhancer/promoter in immature monocytic cells. J. Gen. Virol. 74, 2333-2338.
57. Stinski, M. F., and Roehr, T. S, (1985). Activation of the major immediate early gene of human cytomegalovirus by cis-acting elements in the promoter-regulatory sequence and by virus specific trans-acting components. J. Virol 55, 431-441.
58. Tadmori, W., Mondai, D., Tadmori, I., and Prakash, O. M. (1991). Trans-activation of human immunodeficiency virus type 1 long terminal repeats by cell surface tumor necrosis factor a. J. Virot. 65, 6425-6429.
59. Thomsen, D. R., Stenberg, R. M., Goins, W. F., and Stinski, M. F. (1984). Promoter-regulatory region of the major immediate early gene of human cytomegalovirus. Proc. Natl. Acad. Sci. USA 81, 659-663.
60. Taylor-Wiedeman, J., Sissons, J. G. P., Borysiewicz, L. K., and Sinclair, J. H. (1991). Monocytes are a major site of persistence of human cytomegalovirus in peripheral blood mononuclear cells. J. Gen. Virol. 72, 2059-2064.
61. Vlach, J., and Pitha, P. M. (1992). Herpes simplex virus type 1-mediated induction of human immunodeficiency virus type 1 provirus correlates with binding of nuclear proteins to the NF-kB enhancer and leader sequence. J. Virol. 66, 3616-3623.
62. Weinshenker, B. G., Wilton, S., and Rice, G. P. (1988). Phorbol ester-induced differentiation permits productive human cytomegalovirus infection in a monocytic cell line. J. Immunol. 140, 1625-1631.
63. Wong, G. H. W., Kamb, A., and Goeddel, D. V. (1992), Antiviral properties of TNF. in ‘Tumor Necrosis Factor: The Molecules and Their Emerging Role in Medicine” (B. Beutler, Ed.), pp. 371-381. Raven Press, New York
64. Yang, Z., Costanzo, M., Golde, D. W., and Kolesnick, R. N. (1993). Tumor necrosis factor activation of the shingomyelin pathway signals nuclear factor kB translocation in intact HL-60 cells. J. Biol. Chem. 268, 20520-20523.