Randomised controlled trial comparing problem solving treatment with amitriptyline and placebo for major depression in primary care

BMJ

Volumn 310, Issue 6977, 1995, Pages 441-

  Mynors Wallis, L M ^a   Gath, D H ^a   Lloyd Thomas, A R ^a   Tomlinson, D ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMITRIPTYLINE; PLACEBO;

ADULT; AGED; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEPRESSION; FEASIBILITY STUDY; FEMALE; HAMILTON SCALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; ORAL DRUG ADMINISTRATION; PATIENT CARE; PATIENT SATISFACTION; PRIMARY MEDICAL CARE; PRIORITY JOURNAL; PROBLEM SOLVING; PSYCHOTHERAPY; RANDOMIZED CONTROLLED TRIAL; SELF REPORT; SIDE EFFECT; SYMPTOM; UNITED KINGDOM;

ADOLESCENT; ADULT; AGED; AMITRIPTYLINE; DEPRESSIVE DISORDER; FEMALE; HUMANS; MALE; MIDDLE AGED; PATIENT DROPOUTS; PATIENT SATISFACTION; PATIENT SELECTION; PRIMARY HEALTH CARE; PROBLEM SOLVING; PSYCHIATRIC STATUS RATING SCALES; TREATMENT OUTCOME;

EID: 0028967280     PISSN: 09598138     EISSN: 14685833     Source Type: Journal    
DOI: 10.1136/bmj.310.6977.441     Document Type: Article

References (26)

1. Blacker CVR Clare AW. The prevalence and treatment of depression in general practice. Psychopharmacology 1988; 95: S14–7.
2. Wells KB Stewart A Hays RD Burnam MA Rogers W Daniels M, et al. The functioning and well-being of depressed patients: results from the Medical Outcomes Study. JAMA 1989; 262: 914–9.
3. Johnson DAW Mellor M. The severity of depression in patients treated in general practice. Journal of the Royal College of General Practitioners 1977; 27: 419–22.
4. Porter AMW. Depressive illness in a general practice. A demographic study and a controlled trial of imipramine. BMJ 1970; i: 773–8.
5. Dunn G Skuse D. The natural history of depression in general practice: stochastic models. Psychol Med 1981; 11: 755–64.
6. Stress, distress and drug treatment [editorial]. Lancet 1978; ii: 1347–8.
7. Thomson J Rankin H. Ashcroft GW, Yates CM, McQueen JK, Cummings SJ. The treatment of depression in general practice: a comparison of L-tryptophan, amitriptyline, and a combination of L-tryptophan and amitriptyline with placebo. Psychol Med 1982; 12: 741–51.
8. Richels K Gordon PE Jenkins BW Perloff M Sachs T Stepansky W. Drug treatment in depressive illness. Diseases of the Nervous System 1970; 31: 30–42.
9. Blashki TG Mowbray R Davies B. Controlled trial of amitriptyline in general practice. BMJ 1971; i: 133–8.
10. Paykel ES Hollyman JA Freeling P Sedgewick P. Predictors of therapeutic benefit from amitriptyline in mild depression: a general practice placebo controlled trial. J Affect Disord 1988; 14: 83–95.
11. Johnson DAW. Depression: treatment compliance in general practice. Acta Psychiatr Scand 1981; suppl: 447–63.
12. Blackburn IM Bishop S Glen AIM Walley LJ Christie JE. The efficacy of cognitive therapy in depression. Br J Psychiatry 1981; 139: 181–9.
13. Teasdale JD Fennell MJV Hibbert GA Amies PL. Cognitive therapy for major depression in primary care. Br J Psychiatry 1984; 144: 400–6.
14. Ross M Scott M. An evaluation of the effectiveness of individual and group cognitive therapy in the treatment of depressed patients in an inner city health centre. Journal of the Royal College of General Practitioners 1985; 35: 239–42.
15. Scott AIF Freeman CPL. Edinburgh primary care depression study: treatment outcome, patient satisfaction, and cost after 16 weeks. BMJ 1992; 304: 883–7.
16. Corney RH. Social work effectiveness in the management of depressed women: a clinical trial. Psychol Med 1981; 11: 417–23.
17. Hawton K Kirk J. Problem-solving. In: HawtonKSalkovskisPKirkJClarkDed. Cognitive behaviour therapy for psychiatric problems. Oxford: Oxford University Press, 1989: 406–26.
18. Catalan J Gath DH Bond A Day A Hall L. Evaluation of a brief psychological treatment for emotional disorders in primary care. Psychol Med 1991; 21: 1013–8.
19. Spitzer RL Endicott V Robins E. Research diagnostic criteria: rationale and reliability. Arch Gen Psychiatry 1978; 36: 773–82.
20. Hamilton M. Development of a rating scale for primary depressive illness. British Journal of Social and Clinical Psychology 1967; 6: 278–96.
21. Fawcett J Epstein P Fiester SJ Ellan I Autry J. Clinical management–imipramine/placebo administration manual. Psychopharmacol Bull 1987; 23: 309–24.
22. Wing JK Hooper JE Sartorius N. The measurement and classification of psychiatric symptoms. Cambridge: Cambridge University Press, 1974.
23. Beck AT Ward CH Mendelson M. An inventory for measuring depression. Arch Gen Psychiatry 1961; 4: 561–71.
24. Cooper P Osborn M Gath D Feggetter G. Evaluation of a modified self-report measure of social adjustment. Br J Psychiatry 1982; 141: 68–75.
25. Frank E Prien RF Jarrett RB Keller MB Kupfer DJ Lavori PW, et al. Conceptualization and rationale for consensus definitions of terms in major depressive disorder: remission, recovery, relapse, and recurrence. Arch Gen Psychiatry 1991; 48: 851–5.
26. Depression Guideline Panel. Depression in primary care.Vol 2. Treatment of major depression. Rockville, MD: US Department of Health and Human Services, 1993. (Clinical practice guideline No 5.)