Preoperative infusional chemoradiation and surgery with or without and electron beam intraoperative boost for advanced primary rectal cancer

International Journal of Radiation Oncology, Biology, Physics

Volumn 32, Issue 1, 1995, Pages 197-204

  Weinstein, Geoffrey D ^a   Rich, Tyvin A ^a   Shumate, Charles R ^a   Skibber, John M ^a   Cleary, Karen R ^a   Ajani, Jaffer A ^a   Ota, David M ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

IORT; Preoperative chemoradiotherapy; Rectal cancer

Indexed keywords

CISPLATIN; FLUOROURACIL;

ARTICLE; BEAM THERAPY; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER SURVIVAL; CLINICAL TRIAL; GASTROINTESTINAL TOXICITY; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; LEUKOPENIA; MAJOR CLINICAL STUDY; PEROPERATIVE CARE; PHASE 1 CLINICAL TRIAL; PREOPERATIVE TREATMENT; PRIORITY JOURNAL; RADIATION DOSE; RECTUM CANCER; RECTUM RESECTION; STOMATITIS; SURVIVAL TIME; TREATMENT PLANNING;

ADULT; AGED; AGED, 80 AND OVER; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CHEMOTHERAPY, ADJUVANT; COMPARATIVE STUDY; FEMALE; FOLLOW-UP STUDIES; HUMAN; MALE; MIDDLE AGE; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; PILOT PROJECTS; POSTOPERATIVE COMPLICATIONS; RADIOTHERAPY DOSAGE; RADIOTHERAPY, ADJUVANT; RECTAL NEOPLASMS; SUPPORT, U.S. GOV'T, P.H.S.; SURVIVAL RATE;

EID: 0028966398     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/0360-3016(94)00481-Y     Document Type: Article

References (32)

1. Postoperative radiation therapy for incompletely resected colorectal carcinoma
2. Pharmacologic requirements for obtaining sensitization of human tumor cells in vitro to combined 5-fluorouracil or ftorafur and x-rays
3. Useful interactions between 5-fluorouracil and radiation in man: 5-fluorouracil as a radiosensitizer
4. Recurrence rates after curative surgery for rectal careinoma, with special reference to their accuracy
5. Patterns of recurrence following surgery alone for adenocarcinoma of the colon and rectum
6. Preoperative concurrent 5-Fluorouracil infusion, mitomycin C and pelvic radiation therapy in tethered and fixed rectal carcinoma
7. Preoperative irradiation for unresectable rectal and rectosigmoid carcinomas
8. Low-dose continous infusion cisplatin combined with external beam irradiation for advanced colorectal adenocarcinoma and unresectable nonsmall cell lung cancer
9. Effect of preoperative irradiation on resectability of colorectal carcinomas
10. Preoperative radiation therapy for rectal cancer: An effective therapy in need of a clinical trial
11. Areas of failure found at reoperation (second or symptomatic look) following “curative surgery” for adenocarcinoma of the rectum: Clinicopathologic correlation and implications for adjuvant therapy
12. Intraoperative irradiation for locally advanced colorectal carcinomas
13. Combined modality preoperative therapy in poor prognostic rectal adenocarcinoma
14. A phase III trial of bolus 5-FU versus protracted infusion 5-FU ± cisplatin in metastatic colorectal cancer: An Eastern Cooperative Oncology Group study
15. A prospective randomized comparison of continuous infusion fluorouracil with a conventional bolus schedule in metastatic colorectal carcinoma: A Mid-Atlantic Oncology Program study
16. Local recurrence after potentially curative resection for rectal cancer in a series of 1008 patients
17. Initially unresectable rectal adenocarcinoma treated with preoperative irradiation and surgery
18. Enhancement of radiation-induced downstaging of rectal cancer by fluorouracil and high-dose leucoverin chemotherapy
19. Resectable adenocarcinoma of the rectosigmoid and rectum I. Patterns of failure and survival
20. Preoperative combined 5-FU, low dose leucovorin, and sequential radiation therapy for unresectable rectal cancer
21. High dose preoperative irradiation for cancer of the rectum, 1976–1988
22. Local tumor recurrence after curative resection for rectal cancer: A ten-hospital review
23. Protracted venous infusion (PVI) 5-Fluorouracil (5FU) as a component of effective combined modality postopertative surgical adjuvant therapy for high-risk rectal cancer
24. Chemoradiation for gastrointestinal cancer
25. Chemoradiation therapy for anal cancer: Radiation plus continuous infusion of 5-fluorouracil with or without cisplatin
26. Patterns of recurrence of rectal cancer after potentially curative surgery
27. End results of a multicentric randomized trial comparing 5-FU in continuous systemic infusion (CI) to bolus administration (B) in measurable metastatic colorectal cancer (MCC)
28. Long-term survival and patterns of failure after post-operative radiation therapy for subtotally resected rectal adenocarcinoma
29. Preoperative chemotherapy and radiation therapy for locally advanced primary and recurrent rectal carcinoma: A report of surgical morbidity
30. Comparison of continuously infused 5-fluorouracil with bolus injection in treatment of patients with colorectal adenocarcinoma
31. A randomized trial of continuous systemic infusion (SI) vs. bolus therapy (B) with 5-fluorouracil (5-FU) in metastatic measurable colorectal cancer (MCC)
32. Intraoperative electron beam radiation therapy for primary locally advanced rectal and rectosigmoid carcinoma