메뉴 건너뛰기




Volumn 9, Issue 2, 1995, Pages 475-506

Physiologic mechanisms of therapeutic resistance: Blood flow and hypoxia

Author keywords

[No Author keywords available]

Indexed keywords

2,3 DIPHOSPHOGLYCERIC ACID; ANGIOTENSIN; BLEOMYCIN; CALCIUM CHANNEL BLOCKING AGENT; CARBOGEN; CARMUSTINE; CISPLATIN; CYCLOPHOSPHAMIDE; FLUNARIZINE; FLUOSOL; HEMOGLOBIN; HYDRALAZINE; MELPHALAN; NICOTINAMIDE; NITRIC OXIDE; NITROPRUSSIDE SODIUM; NITROSOUREA DERIVATIVE; OXYGEN; PENTOXIFYLLINE; PERFLUORO COMPOUND; PERFLUOROOCTYL BROMIDE; VERAPAMIL;

EID: 0028964971     PISSN: 08898588     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0889-8588(18)30105-9     Document Type: Review
Times cited : (82)

References (170)
  • 1
    • 0024352361 scopus 로고
    • Enhancement of the anti-tumor effect of melphalan in experimental mice by some vaso-active agents
    • G.E. Adams I.J. Stratfore J. Godden Enhancement of the anti-tumor effect of melphalan in experimental mice by some vaso-active agents Int J Radiat Oncol Biol Plays 16 1989 1137 1139
    • (1989) Int J Radiat Oncol Biol Plays , vol.16 , pp. 1137-1139
    • Adams, G.E.1    Stratfore, I.J.2    Godden, J.3
  • 2
    • 0014572592 scopus 로고
    • Experimental radiotherapy of a rat rhabdomyosarcoma with 15 MeV neutrons and 300 kV x-rays. I. Effects of single exposures
    • G.W. Barendsen J.J. Broerse Experimental radiotherapy of a rat rhabdomyosarcoma with 15 MeV neutrons and 300 kV x-rays. I. Effects of single exposures Eur J Cancer 5 1969 373 391
    • (1969) Eur J Cancer , vol.5 , pp. 373-391
    • Barendsen, G.W.1    Broerse, J.J.2
  • 3
    • 0016231188 scopus 로고
    • Survival responses of dividing and nondividing mammalian cells after treatment with hydroxyurea, arabinosylcytosine, or Adriamycin
    • S.C. Barranco J.K. Novak Survival responses of dividing and nondividing mammalian cells after treatment with hydroxyurea, arabinosylcytosine, or Adriamycin Cancer Res 34 1974 1616 1618
    • (1974) Cancer Res , vol.34 , pp. 1616-1618
    • Barranco, S.C.1    Novak, J.K.2
  • 4
    • 0015611690 scopus 로고
    • Response of mammalian cells following treatment with bleomycin and 1, 3-bis(2-chloroethyl)-1-nitrosourea during plateau phase
    • S.C. Barranco J.K. Novak R.M. Humphrey Response of mammalian cells following treatment with bleomycin and 1, 3-bis(2-chloroethyl)-1-nitrosourea during plateau phase Cancer Res 33 1973 691 694
    • (1973) Cancer Res , vol.33 , pp. 691-694
    • Barranco, S.C.1    Novak, J.K.2    Humphrey, R.M.3
  • 5
    • 0026553517 scopus 로고
    • Determination of changes in tumor blood perfusion after hydralazine treatment by dynamic paramagnetic-enhanced magnetic resonsance imaging
    • C.A. Belfi L.-L. Ting S.J. Hassenbusch Determination of changes in tumor blood perfusion after hydralazine treatment by dynamic paramagnetic-enhanced magnetic resonsance imaging Int J Radiat Oncol Biol Phys 22 1992 477 482
    • (1992) Int J Radiat Oncol Biol Phys , vol.22 , pp. 477-482
    • Belfi, C.A.1    Ting, L.-L.2    Hassenbusch, S.J.3
  • 6
    • 0017597307 scopus 로고
    • Cell proliferation kinetics and drug sensitivity of exponential and stationary populations of cultured L1210 cells
    • B.K. Bhuyan T.J. Fraser K.J. Day Cell proliferation kinetics and drug sensitivity of exponential and stationary populations of cultured L1210 cells Cancer Res 37 1977 1057 1063
    • (1977) Cancer Res , vol.37 , pp. 1057-1063
    • Bhuyan, B.K.1    Fraser, T.J.2    Day, K.J.3
  • 7
    • 0017200280 scopus 로고
    • The effect of prolonged hypoxia on growth and viability of Chinese hamster ovary cells
    • R. Born O. Hug K.R. Trott The effect of prolonged hypoxia on growth and viability of Chinese hamster ovary cells Int J Radiat Oncol Biol Phys 1 1976 687 697
    • (1976) Int J Radiat Oncol Biol Phys , vol.1 , pp. 687-697
    • Born, R.1    Hug, O.2    Trott, K.R.3
  • 8
    • 0019426022 scopus 로고
    • Interactions of organic phosphates with bovine hemoglob Oxylabile F I. phosphate-labile proton binding
    • P.M. Breepel F. Kreuzer M. Hazevoet Interactions of organic phosphates with bovine hemoglob Oxylabile F I. phosphate-labile proton binding Pflugers Arch 389 1981 219
    • (1981) Pflugers Arch , vol.389 , pp. 219
    • Breepel, P.M.1    Kreuzer, F.2    Hazevoet, M.3
  • 9
    • 0015210116 scopus 로고
    • Differences in the interaction of 2,3-diphosphoglycerate with certain mammalian hemoglobins
    • H.F. Bunn Differences in the interaction of 2,3-diphosphoglycerate with certain mammalian hemoglobins Science 172 1971 1049 1050
    • (1971) Science , vol.172 , pp. 1049-1050
    • Bunn, H.F.1
  • 10
    • 0017977265 scopus 로고
    • Definitive evidence for hypoxic cells influencing cure in chemotherapy
    • R.S. Bush R.D.T. Jenkin W.E.C. Alit Definitive evidence for hypoxic cells influencing cure in chemotherapy Br J Cancer 37 Suppl III 1978 302 306
    • (1978) Br J Cancer , vol.37 , Issue.Suppl III , pp. 302-306
    • Bush, R.S.1    Jenkin, R.D.T.2    Alit, W.E.C.3
  • 11
    • 72849184461 scopus 로고
    • Quantitative measurements of oxygen tension in normal tissues and in the tumours of patients before and after radiotherapy
    • D.B. Cater I.A. Silver Quantitative measurements of oxygen tension in normal tissues and in the tumours of patients before and after radiotherapy Acta Radiol 53 1960 23 256
    • (1960) Acta Radiol , vol.53 , pp. 23-256
    • Cater, D.B.1    Silver, I.A.2
  • 12
    • 0023775078 scopus 로고
    • Attempts to find a method to prepare artificial hemoglobin corpuscles
    • T.M.S. Chang Attempts to find a method to prepare artificial hemoglobin corpuscles Biomater Artif Cells Artif Organs 16 1988 1 11
    • (1988) Biomater Artif Cells Artif Organs , vol.16 , pp. 1-11
    • Chang, T.M.S.1
  • 13
    • 0026709522 scopus 로고
    • Blood substitutes based on modified hemoglobin prepared by encapsulation or crosslinking: An overview
    • T.M.S. Chang Blood substitutes based on modified hemoglobin prepared by encapsulation or crosslinking: An overview Biomaterial Artificial Cells Immobilization Biotechnology 20 2–4 1992 159 179
    • (1992) Biomaterial Artificial Cells Immobilization Biotechnology , vol.20 , Issue.2–4 , pp. 159-179
    • Chang, T.M.S.1
  • 14
    • 0023804160 scopus 로고
    • Red blood cell substitutes: Microencapsulated hemoglobin and cross- linked hemoglobin including pyridoxylated polyhemoglobin and conjugated hemoglobin
    • T.M.S. Chang Red blood cell substitutes: Microencapsulated hemoglobin and cross- linked hemoglobin including pyridoxylated polyhemoglobin and conjugated hemoglobin Biomat Art Cells Immobiol Biotech 16 1988 11 29
    • (1988) Biomat Art Cells Immobiol Biotech , vol.16 , pp. 11-29
    • Chang, T.M.S.1
  • 15
    • 0024500292 scopus 로고
    • Hydralazine-induced tumor hypoxia: A potential target for cancer chemotherapy
    • D.J. Chaplin Hydralazine-induced tumor hypoxia: A potential target for cancer chemotherapy J Natl Cancer Inst 81 1989 618 622
    • (1989) J Natl Cancer Inst , vol.81 , pp. 618-622
    • Chaplin, D.J.1
  • 16
    • 0024333795 scopus 로고
    • Potentiation of the tumor cytotoxicity of melphalan by vasodilating drugs
    • D.J. Chaplin B. Acker P.L. Olive Potentiation of the tumor cytotoxicity of melphalan by vasodilating drugs Int J Radiat Oncol Biol Phys 16 1989 1131 1135
    • (1989) Int J Radiat Oncol Biol Phys , vol.16 , pp. 1131-1135
    • Chaplin, D.J.1    Acker, B.2    Olive, P.L.3
  • 17
    • 0026534777 scopus 로고
    • Tumor blood flow changes induced by chemical modifiers of radiation response
    • D.J. Chaplin M.R. Horsman Tumor blood flow changes induced by chemical modifiers of radiation response Int J Radiat Oncol Biol Phys 22 1992 459 462
    • (1992) Int J Radiat Oncol Biol Phys , vol.22 , pp. 459-462
    • Chaplin, D.J.1    Horsman, M.R.2
  • 18
    • 0025264546 scopus 로고
    • The effect of nicotinamide on microregional heterogeneity of oxygen delivery within a murine tumor
    • D.J. Chaplin M.R. Horsman M.J. Trotter The effect of nicotinamide on microregional heterogeneity of oxygen delivery within a murine tumor J Natl Cancer Inst 82 1990 672 676
    • (1990) J Natl Cancer Inst , vol.82 , pp. 672-676
    • Chaplin, D.J.1    Horsman, M.R.2    Trotter, M.J.3
  • 19
    • 84935621249 scopus 로고
    • Immunologic properties of stroma vs. stroma-free hemoglobin solution
    • A. Cochen T.K. Das Gupta R. DeWoskin Immunologic properties of stroma vs. stroma-free hemoglobin solution J Surg Oncol 4 1974 19
    • (1974) J Surg Oncol , vol.4 , pp. 19
    • Cochen, A.1    Das Gupta, T.K.2    DeWoskin, R.3
  • 20
    • 0019352051 scopus 로고
    • Oxygen-binding and immunological properties of complexes between dextran and animal hemoglobins
    • P.G. Cunnington S.N. Jenkins S.C. Tam Oxygen-binding and immunological properties of complexes between dextran and animal hemoglobins Biochem J 193 1981 261 266
    • (1981) Biochem J , vol.193 , pp. 261-266
    • Cunnington, P.G.1    Jenkins, S.N.2    Tam, S.C.3
  • 21
    • 0002240218 scopus 로고
    • Angiogenesis and blood flow
    • M.W. Dewhirst Angiogenesis and blood flow BA Teicher Drug Resistance in Oncology 1993 Marcel Dekker New York 3 24
    • (1993) , pp. 3-24
    • Dewhirst, M.W.1
  • 22
    • 0026482591 scopus 로고
    • Effects of the calcium channel blocker flunarizine on tumor microvascular hemodynamics and oxygenation
    • M.W. Dewhirst E.T. Ong D. Jadwed Effects of the calcium channel blocker flunarizine on tumor microvascular hemodynamics and oxygenation Radiat Res 132 1992 61 68
    • (1992) Radiat Res , vol.132 , pp. 61-68
    • Dewhirst, M.W.1    Ong, E.T.2    Jadwed, D.3
  • 23
    • 0025130936 scopus 로고
    • The use of hydralazine to manipulate tumour temperatures during hyperthermia
    • M.W. Dewhirst D.M. Prescott S. Clegg The use of hydralazine to manipulate tumour temperatures during hyperthermia Int J Hyperthermia 6 1990 971 983
    • (1990) Int J Hyperthermia , vol.6 , pp. 971-983
    • Dewhirst, M.W.1    Prescott, D.M.2    Clegg, S.3
  • 24
    • 0015568184 scopus 로고
    • Exploitation of the oxygen enhancement ratio in clinical practice
    • W. Duncan Exploitation of the oxygen enhancement ratio in clinical practice Br Med Bull 29 1973 33
    • (1973) Br Med Bull , vol.29 , pp. 33
    • Duncan, W.1
  • 25
    • 0027240060 scopus 로고
    • Lack of complications in long-term survivors after treatment with Fluosol® and oxygen as an adjuvant to radiation therapy for high-grade brain tumors
    • R.G. Evans B.F. Kinder R.A. Morantz Lack of complications in long-term survivors after treatment with Fluosol® and oxygen as an adjuvant to radiation therapy for high-grade brain tumors Int J Radiat Oncol Biol Phys 26 1993 649 652
    • (1993) Int J Radiat Oncol Biol Phys , vol.26 , pp. 649-652
    • Evans, R.G.1    Kinder, B.F.2    Morantz, R.A.3
  • 26
    • 0025182414 scopus 로고
    • A Phase I/II study of the use of Fluosol®-DA 20% as an adjuvant to radiation therapy in the treatment of primary high-grade brain tumors
    • R.G. Evans B.F. Kimler R.A. Morantz A Phase I/II study of the use of Fluosol®-DA 20% as an adjuvant to radiation therapy in the treatment of primary high-grade brain tumors Int J Radiat Oncol Biol Phys 19 1990 415 420
    • (1990) Int J Radiat Oncol Biol Phys , vol.19 , pp. 415-420
    • Evans, R.G.1    Kimler, B.F.2    Morantz, R.A.3
  • 27
    • 0026508607 scopus 로고
    • Effect of flunarizine on micro-regional distributions of intravascular HbO2 saturations in RIF-1 and KHT sarcomas
    • B.M. Fenton R.M. Sutherland Effect of flunarizine on micro-regional distributions of intravascular HbO2 saturations in RIF-1 and KHT sarcomas Int J Radiat Oncol Biol Phys 22 1992 447 450
    • (1992) Int J Radiat Oncol Biol Phys , vol.22 , pp. 447-450
    • Fenton, B.M.1    Sutherland, R.M.2
  • 28
    • 0004796379 scopus 로고
    • Distribution of oxygen pressure in the periphery and centre of malignant head and neck tumours
    • W. Fleckenstein Distribution of oxygen pressure in the periphery and centre of malignant head and neck tumours 1990 Blackwell Ueberreuter Wissenchaft Berlin k81 k90
    • (1990) , pp. k81-k90
    • Fleckenstein, W.1
  • 29
    • 0014933855 scopus 로고
    • Carbon monoxide and the partial pressure of oxygen in tissue
    • R.E. Forster Carbon monoxide and the partial pressure of oxygen in tissue Ann NJ Acad Sci 174 1970 233 241
    • (1970) Ann NJ Acad Sci , vol.174 , pp. 233-241
    • Forster, R.E.1
  • 30
    • 0002730614 scopus 로고
    • Pre-therapeutic experiments with the fast neutron beam from the medical research council cyclotron
    • J.F. Fowler R.L. Morgan C.A.P. Wood Pre-therapeutic experiments with the fast neutron beam from the medical research council cyclotron Brit J Radiol 36 1963 77 80
    • (1963) Brit J Radiol , vol.36 , pp. 77-80
    • Fowler, J.F.1    Morgan, R.L.2    Wood, C.A.P.3
  • 32
    • 0018597250 scopus 로고
    • Optimal hematocrit for canine skeletal muscle during rhythmic isotomic exercise
    • P. Gaehtgens P. Kreutz K.H. Albrecht Optimal hematocrit for canine skeletal muscle during rhythmic isotomic exercise Eur J Appl Physiol 41 1979 27 39
    • (1979) Eur J Appl Physiol , vol.41 , pp. 27-39
    • Gaehtgens, P.1    Kreutz, P.2    Albrecht, K.H.3
  • 33
    • 0021846311 scopus 로고
    • Oxygen tension in human tumours: In vivo mapping using CT-guided probes
    • R.A. Gatenby L.R. Coia M.P. Richter Oxygen tension in human tumours: In vivo mapping using CT-guided probes Radiology 156 1985 211 214
    • (1985) Radiology , vol.156 , pp. 211-214
    • Gatenby, R.A.1    Coia, L.R.2    Richter, M.P.3
  • 34
    • 0023932431 scopus 로고
    • Oxygen distribution in squamous cell carcinoma metastases and its relationship to outcome of therapy
    • R.A. Gatenby H.B. Kessler J.S. Rosenblum Oxygen distribution in squamous cell carcinoma metastases and its relationship to outcome of therapy Int J Radiat Oncol Biol Phys 14 1988 831 838
    • (1988) Int J Radiat Oncol Biol Phys , vol.14 , pp. 831-838
    • Gatenby, R.A.1    Kessler, H.B.2    Rosenblum, J.S.3
  • 35
    • 0003680152 scopus 로고
    • The Pharmacological Basis of Therapeutics
    • A.G. Gilman T.W. Rail A.S. Nies The Pharmacological Basis of Therapeutics ed 8 1990 Pergamon Press New York
    • (1990)
    • Gilman, A.G.1    Rail, T.W.2    Nies, A.S.3
  • 36
    • 0017247945 scopus 로고
    • In vivo utilization of oxygen and glucose by neoplastic tissue
    • P.M. Gullino In vivo utilization of oxygen and glucose by neoplastic tissue Adv Exp Med Biol 75 1975 521 536
    • (1975) Adv Exp Med Biol , vol.75 , pp. 521-536
    • Gullino, P.M.1
  • 37
    • 0023028474 scopus 로고
    • Adaptation to low pH modifies thermal and thermochemical responses of mammalian cells
    • G.M. Hahn E.C. Shiu Adaptation to low pH modifies thermal and thermochemical responses of mammalian cells Int J Hyperthermia 2 1986 379 387
    • (1986) Int J Hyperthermia , vol.2 , pp. 379-387
    • Hahn, G.M.1    Shiu, E.C.2
  • 38
    • 0003605672 scopus 로고
    • Radiobiology for the Radiobiologist
    • E.J. Hall Radiobiology for the Radiobiologist ed 2 1978 Harper & Row Philadelphia 235 243
    • (1978) , pp. 235-243
    • Hall, E.J.1
  • 39
    • 0016356833 scopus 로고
    • Vascular resistance and oxygen transport as functions of haematocrit
    • D.F.J. Halmagyi A.H. Goodman Vascular resistance and oxygen transport as functions of haematocrit Resuscitation 3 1974 165 170
    • (1974) Resuscitation , vol.3 , pp. 165-170
    • Halmagyi, D.F.J.1    Goodman, A.H.2
  • 41
    • 0017379628 scopus 로고
    • Radiotherapy and hyperbaric oxygen in head and neck cancer. Final report of first controlled clinical trial
    • J.M. Henk P.B. Kinkier C.W. Smith Radiotherapy and hyperbaric oxygen in head and neck cancer. Final report of first controlled clinical trial Lancet 2 1977 101 103
    • (1977) Lancet , vol.2 , pp. 101-103
    • Henk, J.M.1    Kinkier, P.B.2    Smith, C.W.3
  • 42
    • 0023915062 scopus 로고
    • Effect of hypoxia and acidosis on the cytotoxicity of four platinum complexes at normal and hyperthermic temperatures
    • T.S. Herman B.A. Teicher L.S. Collins Effect of hypoxia and acidosis on the cytotoxicity of four platinum complexes at normal and hyperthermic temperatures Cancer Res 48 1988 2342 2347
    • (1988) Cancer Res , vol.48 , pp. 2342-2347
    • Herman, T.S.1    Teicher, B.A.2    Collins, L.S.3
  • 43
    • 0024335213 scopus 로고
    • Interaction of hyperthermia and radiation: Hypoxia and acidosis in vitro, tumor subpopulations in vivo
    • T.S. Herman B.A. Teicher S.A. Holden Interaction of hyperthermia and radiation: Hypoxia and acidosis in vitro , tumor subpopulations in vivo Cancer Res 49 1989 3338 3343
    • (1989) Cancer Res , vol.49 , pp. 3338-3343
    • Herman, T.S.1    Teicher, B.A.2    Holden, S.A.3
  • 44
    • 0023852013 scopus 로고
    • Rationale for use of local hyperthermia with radiation therapy and selected anticancer drugs in locally advanced human malignancies
    • T.S. Herman B.A. Teicher M. Jochelson Rationale for use of local hyperthermia with radiation therapy and selected anticancer drugs in locally advanced human malignancies Int J Hyperthermia 4 1988 143 158
    • (1988) Int J Hyperthermia , vol.4 , pp. 143-158
    • Herman, T.S.1    Teicher, B.A.2    Jochelson, M.3
  • 45
    • 0015069234 scopus 로고
    • Effect of induced host anemia on the viability and radiosensitivity of murine malignant cells in vivo
    • H.B. Hewitt E. Blake Effect of induced host anemia on the viability and radiosensitivity of murine malignant cells in vivo Br J Cancer 25 1971 323 336
    • (1971) Br J Cancer , vol.25 , pp. 323-336
    • Hewitt, H.B.1    Blake, E.2
  • 46
    • 85113068254 scopus 로고
    • Oxygen delivery and tumour response
    • R.P. Hill D. Stirling Oxygen delivery and tumour response M Fielden JF Fowler JH Hendry Scott The 8th International Congress of Radiation Research 1987 Taylor and Francis London
    • (1987)
    • Hill, R.P.1    Stirling, D.2
  • 47
    • 0015043548 scopus 로고
    • The effect of anemia on the fraction of hypoxic cells in an experimental tumour
    • R.P. Hill R.S. Bush P. Yeung The effect of anemia on the fraction of hypoxic cells in an experimental tumour Br J Radiol 44 1971 299 304
    • (1971) Br J Radiol , vol.44 , pp. 299-304
    • Hill, R.P.1    Bush, R.S.2    Yeung, P.3
  • 49
    • 0023241026 scopus 로고
    • The influence of haemoglobin affinity for oxygen on tumour radiosensitivity
    • D.G. Hirst P.J. Wood The influence of haemoglobin affinity for oxygen on tumour radiosensitivity Br J Cancer 55 1987 487 491
    • (1987) Br J Cancer , vol.55 , pp. 487-491
    • Hirst, D.G.1    Wood, P.J.2
  • 50
    • 0021674166 scopus 로고
    • The effect of hematocrit on tumour sensitivity to X-rays
    • D.G. Hirst J.L. Hazlehurst J.M. Brown The effect of hematocrit on tumour sensitivity to X-rays Int J Radiat Biol 46 1984 345 354
    • (1984) Int J Radiat Biol , vol.46 , pp. 345-354
    • Hirst, D.G.1    Hazlehurst, J.L.2    Brown, J.M.3
  • 51
    • 0023639591 scopus 로고
    • The modification of tumor radiosensitivity by antilipidemic drags
    • D.G. Hirst P.J. Wood H.C. Schwartz The modification of tumor radiosensitivity by antilipidemic drags Radiat Res 112 1987 164 172
    • (1987) Radiat Res , vol.112 , pp. 164-172
    • Hirst, D.G.1    Wood, P.J.2    Schwartz, H.C.3
  • 52
    • 0026356726 scopus 로고
    • Oxygenation of carcinomas of the uterine cervix: evaluation by computerized 02 tension measurements
    • M. Höckel K. Schienger C. Knoop Oxygenation of carcinomas of the uterine cervix: evaluation by computerized 02 tension measurements Cancer Res 51 1991 6098 6102
    • (1991) Cancer Res , vol.51 , pp. 6098-6102
    • Höckel, M.1    Schienger, K.2    Knoop, C.3
  • 53
    • 0025323548 scopus 로고
    • Addition of a hypoxic cell selective cytotoxic agent (mitomycin C or porfiromycin) to Fluosol-DA®/carbogen/radiation
    • S.A. Holden T.S. Herman B.A. Teicher Addition of a hypoxic cell selective cytotoxic agent (mitomycin C or porfiromycin) to Fluosol-DA®/carbogen/radiation Radiother Oncol 18 1990 59 70
    • (1990) Radiother Oncol , vol.18 , pp. 59-70
    • Holden, S.A.1    Herman, T.S.2    Teicher, B.A.3
  • 54
    • 0022642462 scopus 로고
    • Changes in the response of the RIF-1 tumor to melphalan in vivo induced by inhibitors of nuclear ADP-ribosyl transferase
    • M.R. Horsman D.M. Brown D.G. Hirst Changes in the response of the RIF-1 tumor to melphalan in vivo induced by inhibitors of nuclear ADP-ribosyl transferase Br J Cancer 53 1986 247 254
    • (1986) Br J Cancer , vol.53 , pp. 247-254
    • Horsman, M.R.1    Brown, D.M.2    Hirst, D.G.3
  • 55
    • 0024563098 scopus 로고
    • Tumor radiosensitization by nicotinamide: A result of improved perfusion and oxygenation
    • M.R. Horsman D.J. Chaplin J.M. Brown Tumor radiosensitization by nicotinamide: A result of improved perfusion and oxygenation Radiat Res 118 1989 139 150
    • (1989) Radiat Res , vol.118 , pp. 139-150
    • Horsman, M.R.1    Chaplin, D.J.2    Brown, J.M.3
  • 56
    • 0026600356 scopus 로고
    • Relationship between the hydralazine- induced changes in murine tumor blood supply and mouse blood pressure
    • M.R. Horsman K.L. Christensen J. Overgaard Relationship between the hydralazine- induced changes in murine tumor blood supply and mouse blood pressure Int J Radiat Oncol Biol Phys 22 1992 455 458
    • (1992) Int J Radiat Oncol Biol Phys , vol.22 , pp. 455-458
    • Horsman, M.R.1    Christensen, K.L.2    Overgaard, J.3
  • 57
    • 0014526118 scopus 로고
    • An estimation of changes in the proportions and absolute numbers of hypoxic cells after irradiation of transplanted C3H mouse mammary tumours
    • A.E. Howes An estimation of changes in the proportions and absolute numbers of hypoxic cells after irradiation of transplanted C3H mouse mammary tumours Br J Radiol 42 1969 441 447
    • (1969) Br J Radiol , vol.42 , pp. 441-447
    • Howes, A.E.1
  • 59
    • 0023909330 scopus 로고
    • Determinants of tumor blood flow: A review
    • R.K. Jain Determinants of tumor blood flow: A review Cancer Res 48 1988 2641 2658
    • (1988) Cancer Res , vol.48 , pp. 2641-2658
    • Jain, R.K.1
  • 60
    • 0021700770 scopus 로고
    • Tumor blood flow and 02 availability during hemodilution
    • C. Jung W. Muller-Klieser P. Vaupel Tumor blood flow and 02 availability during hemodilution Adv Exp Med Biol 180 1984 281 291
    • (1984) Adv Exp Med Biol , vol.180 , pp. 281-291
    • Jung, C.1    Muller-Klieser, W.2    Vaupel, P.3
  • 61
    • 0021363164 scopus 로고
    • Blood flow to primary tumors and lymph node metastases in SMT-2A tumor-bearing rats following intravenous flunarizine
    • W.G.J. Kaelin S. Shrivastav R.L. Jirtle Blood flow to primary tumors and lymph node metastases in SMT-2A tumor-bearing rats following intravenous flunarizine Cancer Res 44 1984 896 899
    • (1984) Cancer Res , vol.44 , pp. 896-899
    • Kaelin, W.G.J.1    Shrivastav, S.2    Jirtle, R.L.3
  • 62
    • 0020445088 scopus 로고
    • Effect of verapamil on malignant tissue blood flow in SMT-2A tumor-bearing rats
    • W.G.J. Kaelin S. Shrivastav D.G. Shand Effect of verapamil on malignant tissue blood flow in SMT-2A tumor-bearing rats Cancer Res 42 1982 3944 3949
    • (1982) Cancer Res , vol.42 , pp. 3944-3949
    • Kaelin, W.G.J.1    Shrivastav, S.2    Shand, D.G.3
  • 63
    • 0023792610 scopus 로고
    • pH distributions in spontaneous and isotransplanted rat tumours
    • F. Kallinowski P. Vaupel pH distributions in spontaneous and isotransplanted rat tumours Br J Cancer 58 1988 134 321
    • (1988) Br J Cancer , vol.58 , pp. 134-321
    • Kallinowski, F.1    Vaupel, P.2
  • 64
    • 0025043374 scopus 로고
    • Tumor tissue oxygenation as evaluated by computerized-pO2-histography
    • F. Kallinowski R. Zander M. Höckel Tumor tissue oxygenation as evaluated by computerized-pO2-histography Int J Radiat Oncol Biol Phys 19 1990 953 961
    • (1990) Int J Radiat Oncol Biol Phys , vol.19 , pp. 953-961
    • Kallinowski, F.1    Zander, R.2    Höckel, M.3
  • 65
    • 0015412531 scopus 로고
    • The phenomenon of reoxygenation and its implications for fractionated radiotherapy
    • R.F. Kallman The phenomenon of reoxygenation and its implications for fractionated radiotherapy Radiology 105 1972 135 142
    • (1972) Radiology , vol.105 , pp. 135-142
    • Kallman, R.F.1
  • 67
    • 0025165266 scopus 로고
    • Dose-dependent effects of hydralazine on microcircu- latory function and hyperthermic response of murine FSall tumors
    • J. Kalmus P. Okunieff P. Vaupel Dose-dependent effects of hydralazine on microcircu- latory function and hyperthermic response of murine FSall tumors Cancer Res 50 1990 15 19
    • (1990) Cancer Res , vol.50 , pp. 15-19
    • Kalmus, J.1    Okunieff, P.2    Vaupel, P.3
  • 68
    • 0018914018 scopus 로고
    • The hypoxic tumor cell: A target for selective cancer chemotherapy
    • K.A. Kennedy B.A. Teicher S.A. Rockwell The hypoxic tumor cell: A target for selective cancer chemotherapy Biochem Pharmacol 29 1980 18
    • (1980) Biochem Pharmacol , vol.29 , pp. 18
    • Kennedy, K.A.1    Teicher, B.A.2    Rockwell, S.A.3
  • 69
    • 0021971997 scopus 로고
    • Porfiromycin as a bioreductive alkylating agent with selective toxicity to hypoxic EMT6 tumor cells in vivo and in vitro
    • S.R. Keyes S. Rockwell A.C. Sartorelli Porfiromycin as a bioreductive alkylating agent with selective toxicity to hypoxic EMT6 tumor cells in vivo and in vitro Cancer Res 45 1985 3642 3645
    • (1985) Cancer Res , vol.45 , pp. 3642-3645
    • Keyes, S.R.1    Rockwell, S.2    Sartorelli, A.C.3
  • 70
    • 0024351631 scopus 로고
    • The influence of Fluosol-DA and carbogen breathing on the antitumor effects of cyclophosphamide in vivo
    • G.E. Kim C.W. Song The influence of Fluosol-DA and carbogen breathing on the antitumor effects of cyclophosphamide in vivo Cancer Chemother Pharmacol 25 1989 99 102
    • (1989) Cancer Chemother Pharmacol , vol.25 , pp. 99-102
    • Kim, G.E.1    Song, C.W.2
  • 71
    • 0019911617 scopus 로고
    • Effect of perfluorochemicals on BCNU chemotherapy: Preliminary study in a rat brain tumor model
    • T. Kokunai K. Kuwamura Effect of perfluorochemicals on BCNU chemotherapy: Preliminary study in a rat brain tumor model Surg Neurol 18 1982 258 261
    • (1982) Surg Neurol , vol.18 , pp. 258-261
    • Kokunai, T.1    Kuwamura, K.2
  • 72
    • 0014389382 scopus 로고
    • Intercapillary distance, oxygen tension and local recurrence in cervix cancer
    • P. Kolstad Intercapillary distance, oxygen tension and local recurrence in cervix cancer Scand J Clin Lab Invest 106 1968 145 157 (Suppl)
    • (1968) Scand J Clin Lab Invest , vol.106 , pp. 145-157
    • Kolstad, P.1
  • 73
    • 0023194627 scopus 로고
    • Efficacy of two route chemotherapy using cis- diamrninedichloroplatinum(II) and its antidote, sodium thiosulfate, in combination with angiotensin II in a rat limb tumor
    • T. Kuroiwa K. Aoki S. Toniguchi Efficacy of two route chemotherapy using cis- diamrninedichloroplatinum(II) and its antidote, sodium thiosulfate, in combination with angiotensin II in a rat limb tumor Cancer Res 47 1987 3618 3623
    • (1987) Cancer Res , vol.47 , pp. 3618-3623
    • Kuroiwa, T.1    Aoki, K.2    Toniguchi, S.3
  • 74
    • 0019968372 scopus 로고
    • Synergistic effect of perfluorochemicals on BCNU chemotherapy: Experimental study in a 9L rat brain-tumor model
    • K. Kuwamura T. Kokunai N. Tamaki Synergistic effect of perfluorochemicals on BCNU chemotherapy: Experimental study in a 9L rat brain-tumor model J Neurosurg 57 1982 467 471
    • (1982) J Neurosurg , vol.57 , pp. 467-471
    • Kuwamura, K.1    Kokunai, T.2    Tamaki, N.3
  • 75
    • 0027477360 scopus 로고
    • Oxygenation of head and neck tumors
    • E. Lartigau A.-M. Le Ridant P. Lambin Oxygenation of head and neck tumors Cancer 71 1993 2319 2325
    • (1993) Cancer , vol.71 , pp. 2319-2325
    • Lartigau, E.1    Le Ridant, A.-M.2    Lambin, P.3
  • 76
    • 0017622522 scopus 로고
    • Hemoglobin-02 affinity regulation: DPF, monovalent ions, and hemoglobin concentration
    • M.D. Laver E. Jackson M. Scherperel Hemoglobin-02 affinity regulation: DPF, monovalent ions, and hemoglobin concentration J Appl Physiol 43 1977 632
    • (1977) J Appl Physiol , vol.43 , pp. 632
    • Laver, M.D.1    Jackson, E.2    Scherperel, M.3
  • 77
    • 0026511236 scopus 로고
    • Increases in tumor response by pentoxifylline alone or in combination with nicotinamide
    • I. Lee J.H. Kim S.H. Levitt Increases in tumor response by pentoxifylline alone or in combination with nicotinamide Int J Radiat Oncol Biol Phys 22 1992 425 429
    • (1992) Int J Radiat Oncol Biol Phys , vol.22 , pp. 425-429
    • Lee, I.1    Kim, J.H.2    Levitt, S.H.3
  • 78
    • 0023616893 scopus 로고
    • Effects of Fluosol-DA 20% and carbogen on the radioresponse of SCK tumors and skin of A/J mice
    • I. Lee S.H. Levitt C.W. Song Effects of Fluosol-DA 20% and carbogen on the radioresponse of SCK tumors and skin of A/J mice Radiat Res 112 1987 173 182
    • (1987) Radiat Res , vol.112 , pp. 173-182
    • Lee, I.1    Levitt, S.H.2    Song, C.W.3
  • 79
    • 0025322392 scopus 로고
    • Radiosensitization of murine tumors by Fluosol-DA 20%
    • I. Lee S.H. Levitt C.W. Song Radiosensitization of murine tumors by Fluosol-DA 20% Radiat Res 122 1990 275 279
    • (1990) Radiat Res , vol.122 , pp. 275-279
    • Lee, I.1    Levitt, S.H.2    Song, C.W.3
  • 80
    • 0025194034 scopus 로고
    • Fluosol and oxygen breathing as an adjuvant to radiation therapy in the treatment of locally advanced non-small cell carcinoma of the lung: Results of a phase I/II study
    • R. Lustig N. Lowe L. Prosnitz Fluosol and oxygen breathing as an adjuvant to radiation therapy in the treatment of locally advanced non-small cell carcinoma of the lung: Results of a phase I/II study Int J Radiat Oncol Biol Phys 19 1990 97 102
    • (1990) Int J Radiat Oncol Biol Phys , vol.19 , pp. 97-102
    • Lustig, R.1    Lowe, N.2    Prosnitz, L.3
  • 81
    • 0024380933 scopus 로고
    • Phase I/II study of Fluosol-DA and 100% oxygen breathing as an adjuvant to radiation in the treatment of advanced squamous cell tumors of the head and neck
    • R. Lustig N.L. Mclntosh-Lowe C. Rose Phase I/II study of Fluosol-DA and 100% oxygen breathing as an adjuvant to radiation in the treatment of advanced squamous cell tumors of the head and neck Int J Radiat Oncol Biol Phys 16 1989 1587 1594
    • (1989) Int J Radiat Oncol Biol Phys , vol.16 , pp. 1587-1594
    • Lustig, R.1    Mclntosh-Lowe, N.L.2    Rose, C.3
  • 82
    • 0023831233 scopus 로고
    • Potentiation of rat brain tumor therapy by Fluosol and carbogen
    • D.F. Martin B.F. Kinder R.G. Evans Potentiation of rat brain tumor therapy by Fluosol and carbogen NCI Monographs 6 1988 119 122
    • (1988) NCI Monographs , vol.6 , pp. 119-122
    • Martin, D.F.1    Kinder, B.F.2    Evans, R.G.3
  • 83
    • 0023634812 scopus 로고
    • Effect of a perfluorochemical emulsion on the radiation response of BA-1112 rhabdomyosarcomas
    • D.F. Martin E.A. Porter J.J. Fischer Effect of a perfluorochemical emulsion on the radiation response of BA-1112 rhabdomyosarcomas Radiat Res 112 1987 45 53
    • (1987) Radiat Res , vol.112 , pp. 45-53
    • Martin, D.F.1    Porter, E.A.2    Fischer, J.J.3
  • 84
    • 0027265108 scopus 로고
    • Changes in the oxygenation of head and neck tumors during carbogen breathing
    • L. Martin E. Lartigau P. Weeger Changes in the oxygenation of head and neck tumors during carbogen breathing Radiat Ther Oncol 27 1993 123 130
    • (1993) Radiat Ther Oncol , vol.27 , pp. 123-130
    • Martin, L.1    Lartigau, E.2    Weeger, P.3
  • 85
    • 0018823419 scopus 로고
    • In vitro systems for evaluation of combination chemotherapy
    • R.L. Momparler In vitro systems for evaluation of combination chemotherapy Pharmacol Ther 8(A) 1980 21 35
    • (1980) Pharmacol Ther , vol.8(A) , pp. 21-35
    • Momparler, R.L.1
  • 86
    • 0002715879 scopus 로고
    • On the effect of anaemia on the reactions of skin and of tumors to radium exposure
    • J.C. Mottram A. Eidinow On the effect of anaemia on the reactions of skin and of tumors to radium exposure Br J Surg 19 1932 481 487
    • (1932) Br J Surg , vol.19 , pp. 481-487
    • Mottram, J.C.1    Eidinow, A.2
  • 87
    • 0023796743 scopus 로고
    • Intermittent use of a perfluorochemical emulsion (Fluosol-DA 20%) and carbogen breathing with fractionated irradiation
    • J.E. Moulder B.L. Fish Intermittent use of a perfluorochemical emulsion (Fluosol-DA 20%) and carbogen breathing with fractionated irradiation Int J Radiat Oncol Biol Phys 15 1988 1193 1196
    • (1988) Int J Radiat Oncol Biol Phys , vol.15 , pp. 1193-1196
    • Moulder, J.E.1    Fish, B.L.2
  • 89
    • 0017122960 scopus 로고
    • Time-dose relationships for the cure of an experimental rat tumor with fractionated radiation
    • J.E. Moulder J.J. Fischer R. Milardo Time-dose relationships for the cure of an experimental rat tumor with fractionated radiation Int J Radiat Oncol Biol Phys 1 1976 431 438
    • (1976) Int J Radiat Oncol Biol Phys , vol.1 , pp. 431-438
    • Moulder, J.E.1    Fischer, J.J.2    Milardo, R.3
  • 90
    • 0027261178 scopus 로고
    • Oxygen tension distributions are sufficient to explain the local response of human breast tumors treated with radiation alone
    • P. Okunieff M. Hoeckel E.P. Dunphy Oxygen tension distributions are sufficient to explain the local response of human breast tumors treated with radiation alone Int J Radiat Oncol Biol Phys 26 1993 631 636
    • (1993) Int J Radiat Oncol Biol Phys , vol.26 , pp. 631-636
    • Okunieff, P.1    Hoeckel, M.2    Dunphy, E.P.3
  • 91
    • 0023694816 scopus 로고
    • Effects of hydralazine-induced vasodilation on the energy metabolism of murine tumors studied by in vivo 31 P-nuclear magnetic resonance spectroscopy
    • P. Okunieff F. Kallinowski P. Vaupel Effects of hydralazine-induced vasodilation on the energy metabolism of murine tumors studied by in vivo 31 P-nuclear magnetic resonance spectroscopy J Natl Cancer Inst 80 1988 745 750
    • (1988) J Natl Cancer Inst , vol.80 , pp. 745-750
    • Okunieff, P.1    Kallinowski, F.2    Vaupel, P.3
  • 92
    • 0024348111 scopus 로고
    • Effects of hydralazine on in vivo tumor energy metabolism, hematopoietic radiation sensitivity, and cardiovascular parameters
    • P. Okunieff C.S. Walsh P. Vaupel Effects of hydralazine on in vivo tumor energy metabolism, hematopoietic radiation sensitivity, and cardiovascular parameters Int J Radiat Oncol Biol Phys 16 1989 1145 1148
    • (1989) Int J Radiat Oncol Biol Phys , vol.16 , pp. 1145-1148
    • Okunieff, P.1    Walsh, C.S.2    Vaupel, P.3
  • 93
    • 0026581420 scopus 로고
    • Blood flow modification in the SCCVII tumor: Effects of 5-hydroxytryptamine, hydralazine, and propranolol
    • C.E. Peters D.J. Chaplin Blood flow modification in the SCCVII tumor: Effects of 5-hydroxytryptamine, hydralazine, and propranolol Int J Radiat Oncol Biol Phys 22 1992 463 465
    • (1992) Int J Radiat Oncol Biol Phys , vol.22 , pp. 463-465
    • Peters, C.E.1    Chaplin, D.J.2
  • 94
    • 0000168995 scopus 로고
    • A multicomponent x-ray survival curve for mouse lymphosarcoma cells irradiated in vivo
    • W.E. Powers L.J. Tolmach A multicomponent x-ray survival curve for mouse lymphosarcoma cells irradiated in vivo Nature 197 1963 710 711
    • (1963) Nature , vol.197 , pp. 710-711
    • Powers, W.E.1    Tolmach, L.J.2
  • 95
    • 0026666932 scopus 로고
    • Use of nitroprusside to increase tissue temperature during local hyperthermia in normal and tumor-bearing dogs
    • D.M. Prescott T.V. Samulski M.W. Dewhirst Use of nitroprusside to increase tissue temperature during local hyperthermia in normal and tumor-bearing dogs Int J Radiat Oncol Biol Phys 23 1992 377 385
    • (1992) Int J Radiat Oncol Biol Phys , vol.23 , pp. 377-385
    • Prescott, D.M.1    Samulski, T.V.2    Dewhirst, M.W.3
  • 96
    • 0001502640 scopus 로고
    • Distribution of acid-soluble phosphorous in the blood cells of various vertebrates
    • S. Rapoport G.M. Guest Distribution of acid-soluble phosphorous in the blood cells of various vertebrates J Biol Chem 138 1941 269 280
    • (1941) J Biol Chem , vol.138 , pp. 269-280
    • Rapoport, S.1    Guest, G.M.2
  • 97
    • 0014314829 scopus 로고
    • Tumour cure rate and cell survival of a transplantable rat rhabdomyosarcoma following x-irradiation
    • H.S. Reinhold C. De Bree Tumour cure rate and cell survival of a transplantable rat rhabdomyosarcoma following x-irradiation Eur J Cancer 4 1968 367 374
    • (1968) Eur J Cancer , vol.4 , pp. 367-374
    • Reinhold, H.S.1    De Bree, C.2
  • 98
    • 0015583407 scopus 로고
    • Cellular radiosensitivity and tumor radiation response in the EMT-6 tumor cell system
    • S. Rockwell R.F. Kallman Cellular radiosensitivity and tumor radiation response in the EMT-6 tumor cell system Radiat Res 53 1973 281 294
    • (1973) Radiat Res , vol.53 , pp. 281-294
    • Rockwell, S.1    Kallman, R.F.2
  • 99
    • 0022457633 scopus 로고
    • Reactions of tumors and normal tissues in mice to irradiation in the presence and absence of a perfluorochemical emulsion
    • S. Rockwell T.P. Mato C.G. Irvin Reactions of tumors and normal tissues in mice to irradiation in the presence and absence of a perfluorochemical emulsion Int J Radiat Oncol Biol Phys 12 1986 1315 1318
    • (1986) Int J Radiat Oncol Biol Phys , vol.12 , pp. 1315-1318
    • Rockwell, S.1    Mato, T.P.2    Irvin, C.G.3
  • 100
    • 0022521907 scopus 로고
    • A clinical trial of Fluosol-DA 20% in advanced squamous cell carcinoma of the head and neck
    • C.M. Rose R. Lustig N. McIntosh A clinical trial of Fluosol-DA 20% in advanced squamous cell carcinoma of the head and neck Int J Radiat Oncol Biol Phys 12 1986 1325 1327
    • (1986) Int J Radiat Oncol Biol Phys , vol.12 , pp. 1325-1327
    • Rose, C.M.1    Lustig, R.2    McIntosh, N.3
  • 101
    • 0023902264 scopus 로고
    • Therapeutic attack of hypoxic cells of solid tumors: Presidential address
    • A.C. Sartorelli Therapeutic attack of hypoxic cells of solid tumors: Presidential address Cancer Res 48 1988 775
    • (1988) Cancer Res , vol.48 , pp. 775
    • Sartorelli, A.C.1
  • 102
    • 85113069702 scopus 로고
    • Detection of radiobiological hypoxia in cancers of the cervix and the breast: Evaluation by computerized O, tension measurements in patients
    • K.H. Schienger M. Hoeckel P. Vaupel Detection of radiobiological hypoxia in cancers of the cervix and the breast: Evaluation by computerized O, tension measurements in patients 1991 Geneva Park Canada
    • (1991)
    • Schienger, K.H.1    Hoeckel, M.2    Vaupel, P.3
  • 103
    • 0002017562 scopus 로고
    • Morphological assessment of skeletal muscular injury caused by p02 measurements with hypodemic needle probes
    • U. Schramm W. Fleckenstein C. Weber Morphological assessment of skeletal muscular injury caused by p02 measurements with hypodemic needle probes A.M. Ehrly W. Fleckenstein J. Hauss R. Huch Clinial Oxygen Pressure Measurement 1990 Blackwell Ueberreuter Wissenschaft Berlin 38 50
    • (1990) , pp. 38-50
    • Schramm, U.1    Fleckenstein, W.2    Weber, C.3
  • 104
    • 0024411217 scopus 로고
    • Geometric resistance to blood flow in solid tumors perfused ex vivo: Effects of tumor size and perfusion pressure
    • E.M. Sevick R.K. Jain Geometric resistance to blood flow in solid tumors perfused ex vivo: Effects of tumor size and perfusion pressure Cancer Res 49 1989 3513 3519
    • (1989) Cancer Res , vol.49 , pp. 3513-3519
    • Sevick, E.M.1    Jain, R.K.2
  • 105
    • 0023688667 scopus 로고
    • Characterization of radiation resistant hypoxic cell subpopulations in KHT sarcomas. (ii) Cell sorting
    • D.W. Siemann P.C. Keng Characterization of radiation resistant hypoxic cell subpopulations in KHT sarcomas. (ii) Cell sorting Br J Cancer 58 1988 296 300
    • (1988) Br J Cancer , vol.58 , pp. 296-300
    • Siemann, D.W.1    Keng, P.C.2
  • 106
    • 0022457629 scopus 로고
    • Tumor radiosensitization through reductions in hemoglobin affinity
    • D.W. Siemann L.M. Macier Tumor radiosensitization through reductions in hemoglobin affinity Int J Radiat Oncol Biol Phys 12 1986 1295 1297
    • (1986) Int J Radiat Oncol Biol Phys , vol.12 , pp. 1295-1297
    • Siemann, D.W.1    Macier, L.M.2
  • 107
    • 0016687912 scopus 로고
    • The relationship between mouse arterial partial pressure of oxygen (Pao2) and the effectiveness of localized tumour irradiation
    • D.W. Siemann M.J. Bronskill R.P. Hill The relationship between mouse arterial partial pressure of oxygen (Pao2) and the effectiveness of localized tumour irradiation Br J Radiol 48 1975 662 667
    • (1975) Br J Radiol , vol.48 , pp. 662-667
    • Siemann, D.W.1    Bronskill, M.J.2    Hill, R.P.3
  • 108
    • 0018179096 scopus 로고
    • Smoking: The influence of carboxyhemoglobin (HbCO) on tumor oxygenation and response to radiation
    • D.W. Siemann R.P. Hill R.S. Bush Smoking: The influence of carboxyhemoglobin (HbCO) on tumor oxygenation and response to radiation Int J Radiat Oncol Biol Phys 4 1978 657 662
    • (1978) Int J Radiat Oncol Biol Phys , vol.4 , pp. 657-662
    • Siemann, D.W.1    Hill, R.P.2    Bush, R.S.3
  • 109
    • 0018379496 scopus 로고
    • The in vivo radiation response of an experimental tumor: The effect of exposing tumor-bearing mice to reduced oxygen environment prior to but not during irradiation
    • D.W. Siemann R.P. Hill R.S. Bush The in vivo radiation response of an experimental tumor: The effect of exposing tumor-bearing mice to reduced oxygen environment prior to but not during irradiation Int J Radiat Oncol Biol Phys 5 1979 61 68
    • (1979) Int J Radiat Oncol Biol Phys , vol.5 , pp. 61-68
    • Siemann, D.W.1    Hill, R.P.2    Bush, R.S.3
  • 110
    • 0343872397 scopus 로고
    • Investigation on the reproducibility of intramuscular pO2 measurement in patients by means of the tissue pO2-Histograph Kimoc/Sigma
    • G. Singbartl G. Metzger G. Beister Investigation on the reproducibility of intramuscular pO2 measurement in patients by means of the tissue pO2-Histograph Kimoc/Sigma A.M. Ehrly W. Fleckenstein J. Hauss R. Huch Clinical Oxygen Pressure Measurement 1990 Blackwell Ueberreuter Wissenschaft Berlin 25 29
    • (1990) , pp. 25-29
    • Singbartl, G.1    Metzger, G.2    Beister, G.3
  • 111
    • 0016653915 scopus 로고
    • Nitroprusside produces cyanide poisoning via a reaction with hemoglobin
    • R.P. Smith H. Kruszyna Nitroprusside produces cyanide poisoning via a reaction with hemoglobin J Pharmacol Exp Ther 191 1974 557 563
    • (1974) J Pharmacol Exp Ther , vol.191 , pp. 557-563
    • Smith, R.P.1    Kruszyna, H.2
  • 112
    • 0023164712 scopus 로고
    • Increase in pO2 and radiosensitivity of tumors by Fluosol-DA (20%) and carbogen
    • C.W. Song I. Lee T. Hasegawa Increase in pO2 and radiosensitivity of tumors by Fluosol-DA (20%) and carbogen Cancer Res 47 1987 442 446
    • (1987) Cancer Res , vol.47 , pp. 442-446
    • Song, C.W.1    Lee, I.2    Hasegawa, T.3
  • 113
    • 0023813259 scopus 로고
    • Potentiation of the anti-tumour effect of melphalan by the vasoactive agent, hydralazine
    • I.J. Stratford G.E. Adams J. Godden Potentiation of the anti-tumour effect of melphalan by the vasoactive agent, hydralazine Br J Cancer 58 1988 122 127
    • (1988) Br J Cancer , vol.58 , pp. 122-127
    • Stratford, I.J.1    Adams, G.E.2    Godden, J.3
  • 114
    • 0011276151 scopus 로고
    • Hyperbaric oxygen and radiobiology of the C3H mouse mammary carcinoma
    • H.D. Suit M. Maeda Hyperbaric oxygen and radiobiology of the C3H mouse mammary carcinoma J Natl Cancer Inst 39 1967 639 652
    • (1967) J Natl Cancer Inst , vol.39 , pp. 639-652
    • Suit, H.D.1    Maeda, M.2
  • 115
    • 0142206525 scopus 로고
    • Response of anoxic C3H mouse mammary carcinoma isotransplants (1-25 mm3) to x irradiation
    • H.D. Suit R.J. Shalek Response of anoxic C3H mouse mammary carcinoma isotransplants (1-25 mm3) to x irradiation J Natl Cancer Inst 31 1963 479 493
    • (1963) J Natl Cancer Inst , vol.31 , pp. 479-493
    • Suit, H.D.1    Shalek, R.J.2
  • 116
    • 0014138581 scopus 로고
    • Hyperbaric oxygen and radiotherapy of a fibrosarcoma and of squamous-cell carcinoma of C3H mice
    • H.D. Suit C. Suchato Hyperbaric oxygen and radiotherapy of a fibrosarcoma and of squamous-cell carcinoma of C3H mice Radiology 89 1967 713 719
    • (1967) Radiology , vol.89 , pp. 713-719
    • Suit, H.D.1    Suchato, C.2
  • 117
    • 0022402049 scopus 로고
    • Pentobarbital anesthesia and the response of tumor and normal tissue in the C3Hf/sed mouse to radiation
    • H.D. Suit R.S. Sedlacek G. Silver Pentobarbital anesthesia and the response of tumor and normal tissue in the C3Hf/sed mouse to radiation Radiat Res 104 1985 47 65
    • (1985) Radiat Res , vol.104 , pp. 47-65
    • Suit, H.D.1    Sedlacek, R.S.2    Silver, G.3
  • 118
    • 0019478990 scopus 로고
    • A new approach to cancer chemotherapy: Selective enhancement of tumor blood flow with angiotensin II
    • M. Suzuki K. Hori I. Abe A new approach to cancer chemotherapy: Selective enhancement of tumor blood flow with angiotensin II J Natl Cancer Inst 67 1981 663 669
    • (1981) J Natl Cancer Inst , vol.67 , pp. 663-669
    • Suzuki, M.1    Hori, K.2    Abe, I.3
  • 119
    • 9544221887 scopus 로고
    • Use of fluosol-DA/oxygen breathing with radiation therapy and chemotherapy/radiation combinations
    • B.A. Teicher T.S. Herman Use of fluosol-DA/oxygen breathing with radiation therapy and chemotherapy/radiation combinations M.J. John M.S. Flam S.S. Legha T.L. Phillips Chemoradiation: An Integrated Approach to Cancer Treatment 1993 Lea & Febiger Philadelphia 140 158
    • (1993) , pp. 140-158
    • Teicher, B.A.1    Herman, T.S.2
  • 120
    • 0023101232 scopus 로고
    • Survey of the effect of adding Fluosol-DA 20%/O2 to treatment with various chemotherapeutic agents
    • B.A. Teicher S.A. Holden Survey of the effect of adding Fluosol-DA 20%/O2 to treatment with various chemotherapeutic agents Cancer Treatment Reports 71 1987 173 177
    • (1987) Cancer Treatment Reports , vol.71 , pp. 173-177
    • Teicher, B.A.1    Holden, S.A.2
  • 121
    • 0022516178 scopus 로고
    • Effect of dose and scheduling on growth delay of the Lewis lung carcinoma produced by the perfluorochemical emulsion
    • B.A. Teicher C.M. Rose Effect of dose and scheduling on growth delay of the Lewis lung carcinoma produced by the perfluorochemical emulsion Fluosol-DA. Int J Radiat Oncol Biol Phys 12 1986 1311 1313
    • (1986) Fluosol-DA. Int J Radiat Oncol Biol Phys , vol.12 , pp. 1311-1313
    • Teicher, B.A.1    Rose, C.M.2
  • 122
    • 0021192849 scopus 로고
    • Oxygen-carrying perfluorochemical emulsion as an adjuvant to radiation therapy in mice
    • B.A. Teicher C.M. Rose Oxygen-carrying perfluorochemical emulsion as an adjuvant to radiation therapy in mice Cancer Res 44 1984 4285 4288
    • (1984) Cancer Res , vol.44 , pp. 4285-4288
    • Teicher, B.A.1    Rose, C.M.2
  • 123
    • 0021324649 scopus 로고
    • Perfluorochemical emulsion can increase tumor radiosensitivity
    • B.A. Teicher C.M. Rose Perfluorochemical emulsion can increase tumor radiosensitivity Science 223 1984 934 936
    • (1984) Science , vol.223 , pp. 934-936
    • Teicher, B.A.1    Rose, C.M.2
  • 124
    • 0023922849 scopus 로고
    • Effect of Fluosol-DA/carbogen on etopo- side/alkylating agent antitumor activity
    • B.A. Teicher S.D. Bernal S.A. Holden Effect of Fluosol-DA/carbogen on etopo- side/alkylating agent antitumor activity Cancer Chemother Pharmacol 21 1988 281 285
    • (1988) Cancer Chemother Pharmacol , vol.21 , pp. 281-285
    • Teicher, B.A.1    Bernal, S.D.2    Holden, S.A.3
  • 125
    • 0023205450 scopus 로고
    • Effects of various oxygenation conditions on the enhancement by Fluosol-DA of melphalan antitumor activity
    • B.A. Teicher J.M. Crawford S.A. Holden Effects of various oxygenation conditions on the enhancement by Fluosol-DA of melphalan antitumor activity Cancer Res 47 1987 5036 5041
    • (1987) Cancer Res , vol.47 , pp. 5036-5041
    • Teicher, B.A.1    Crawford, J.M.2    Holden, S.A.3
  • 126
    • 0028132666 scopus 로고
    • Reduced oxygenation in a rat mammary carcinoma post-radiation and reoxygenation with a perflubron emulsion/carbogen breathing
    • B.A. Teicher N.P. Dupuis M.F. Robinson Reduced oxygenation in a rat mammary carcinoma post-radiation and reoxygenation with a perflubron emulsion/carbogen breathing J Cancer Res Clin Oncol 120 1994 593 598
    • (1994) J Cancer Res Clin Oncol , vol.120 , pp. 593-598
    • Teicher, B.A.1    Dupuis, N.P.2    Robinson, M.F.3
  • 127
    • 0026444831 scopus 로고
    • Perfluorochemical emulsions: Oxygen breathing in radiation sensitization and chemotherapy modulation
    • B.A. Teicher T.S. Herman E. Frei III Perfluorochemical emulsions: Oxygen breathing in radiation sensitization and chemotherapy modulation V.T.J. DeVita S. Heilman S.A. Rosenberg Important Advances in Oncology 1992 JB Lippincott Philadelphia 39 59
    • (1992) , pp. 39-59
    • Teicher, B.A.1    Herman, T.S.2    Frei, E.3
  • 128
    • 0023922850 scopus 로고
    • The effect of Fluosol-DA and oxygenation status on the activity of cyclophosphamide in vivo
    • B.A. Teicher T.S. Herman S.A. Holden The effect of Fluosol-DA and oxygenation status on the activity of cyclophosphamide in vivo Cancer Chemother Pharmacol 21 1988 286 291
    • (1988) Cancer Chemother Pharmacol , vol.21 , pp. 286-291
    • Teicher, B.A.1    Herman, T.S.2    Holden, S.A.3
  • 129
    • 0026570069 scopus 로고
    • Effect of a bovine hemoglobin preparation on the response of the FSallC fibrosarcoma to chemotherapeutic alkylating agents
    • B.A. Teicher T.S. Herman R.E. Hopkins Effect of a bovine hemoglobin preparation on the response of the FSallC fibrosarcoma to chemotherapeutic alkylating agents J Cancer Res Clin Oncol 118 1992 123 128
    • (1992) J Cancer Res Clin Oncol , vol.118 , pp. 123-128
    • Teicher, B.A.1    Herman, T.S.2    Hopkins, R.E.3
  • 130
    • 0025162889 scopus 로고
    • Influence of scheduling, dose, and volume of administration of perfluorochemical emulsion on tumor response to radiation therapy
    • B.A. Teicher T.S. Herman S.M. Jones Influence of scheduling, dose, and volume of administration of perfluorochemical emulsion on tumor response to radiation therapy Int J Radiat Oncol Biol Phys 19 1991 945 951
    • (1991) Int J Radiat Oncol Biol Phys , vol.19 , pp. 945-951
    • Teicher, B.A.1    Herman, T.S.2    Jones, S.M.3
  • 131
    • 0024349643 scopus 로고
    • Optimization of perfluorochemical levels with radiation therapy in mice
    • B.A. Teicher T.S. Herman S.M. Jones Optimization of perfluorochemical levels with radiation therapy in mice Cancer Res 49 1989 2693 2697
    • (1989) Cancer Res , vol.49 , pp. 2693-2697
    • Teicher, B.A.1    Herman, T.S.2    Jones, S.M.3
  • 132
    • 0023757153 scopus 로고
    • Effect of Fluosol-DA® on the response of intracranial 9L tumors to x-rays and BCNU
    • B.A. Teicher T.S. Herman C.M. Rose Effect of Fluosol-DA® on the response of intracranial 9L tumors to x-rays and BCNU Int J Radiat Oncol Biol Phys 15 1988 1187 1192
    • (1988) Int J Radiat Oncol Biol Phys , vol.15 , pp. 1187-1192
    • Teicher, B.A.1    Herman, T.S.2    Rose, C.M.3
  • 133
    • 0025354292 scopus 로고
    • Classification of antineoplastic treatments by their differential toxicity toward putative oxygenated and hypoxic tumor subpopulations in vivo in FSallC murine fibrosarcoma
    • B.A. Teicher S.A. Holden A. Al-Achi Classification of antineoplastic treatments by their differential toxicity toward putative oxygenated and hypoxic tumor subpopulations in vivo in FSallC murine fibrosarcoma Cancer Res 50 1990 3339 3344
    • (1990) Cancer Res , vol.50 , pp. 3339-3344
    • Teicher, B.A.1    Holden, S.A.2    Al-Achi, A.3
  • 134
    • 0026673272 scopus 로고
    • Effect of a bovine hemoglobin preparation (SBHS) on the response of two murine solid tumors to radiation therapy or chemotherapeutic alkylating agents
    • B.A. Teicher S.A. Holden G. Ara Effect of a bovine hemoglobin preparation (SBHS) on the response of two murine solid tumors to radiation therapy or chemotherapeutic alkylating agents Biomat Art Cells Immobiol Biotech 20 1992 657 660 (2–4)
    • (1992) Biomat Art Cells Immobiol Biotech , vol.20 , pp. 657-660
    • Teicher, B.A.1    Holden, S.A.2    Ara, G.3
  • 135
    • 0023882522 scopus 로고
    • Effects of Fluosol®-DA and oxygen breathing on Adriamycin antitumor activity and cardiac toxicity in mice
    • B.A. Teicher S.A. Holden J.M. Crawford Effects of Fluosol®-DA and oxygen breathing on Adriamycin antitumor activity and cardiac toxicity in mice Cancer 61 1988 2196 2201
    • (1988) Cancer , vol.61 , pp. 2196-2201
    • Teicher, B.A.1    Holden, S.A.2    Crawford, J.M.3
  • 136
    • 85113073884 scopus 로고    scopus 로고
    • Teicher BA, Holden SA, Dupuis NP, et al: Oxygenation of the rat 9L gliosarcoma and the rat 13672 mammary carcinoma with various doses of a hemoglobin solution. Biomat Art Cells Immobiol Biotech, in press.
  • 137
    • 0023092376 scopus 로고
    • Approaches to defining the mechanism of enhancement by Fluosol-DA 20% with carbogen of melphalan antitumor activity
    • B.A. Teicher S.A. Holden J.L. Jacobs Approaches to defining the mechanism of enhancement by Fluosol-DA 20% with carbogen of melphalan antitumor activity Cancer Res 47 1987 513 518
    • (1987) Cancer Res , vol.47 , pp. 513-518
    • Teicher, B.A.1    Holden, S.A.2    Jacobs, J.L.3
  • 138
    • 85113039775 scopus 로고    scopus 로고
    • Teicher BA, Holden SA, Menon K, et al: Effect of a hemoglobin solution on the response of intracranial and subcutaneous 9L tumors to antitumor alkylating agents. Cancer Chemother Pharmacol, in press.
  • 139
    • 0027310237 scopus 로고
    • Therapeutic effect of infused Fluosol-DA/carbogen with ephedrine, flunarizine, or nitroprusside
    • B.A. Teicher S.A. Holden D. Northey Therapeutic effect of infused Fluosol-DA/carbogen with ephedrine, flunarizine, or nitroprusside Int J Radiat Oncol Biol Phys 26 1993 103 109
    • (1993) Int J Radiat Oncol Biol Phys , vol.26 , pp. 103-109
    • Teicher, B.A.1    Holden, S.A.2    Northey, D.3
  • 140
    • 0022410074 scopus 로고
    • Differential enhancement of melphalan cytotoxicity in tumor and normal tissue by Fluosol-DA and oxygen breathing
    • B.A. Teicher S.A. Holden C.M. Rose Differential enhancement of melphalan cytotoxicity in tumor and normal tissue by Fluosol-DA and oxygen breathing Int J Cancer 36 1985 585 589
    • (1985) Int J Cancer , vol.36 , pp. 585-589
    • Teicher, B.A.1    Holden, S.A.2    Rose, C.M.3
  • 141
    • 0022497349 scopus 로고
    • Effect of Fluosol-DA/O2 on tumor cell and bone marrow cytotoxicity of nitrosoureas in mice bearing FSall fibrosarcoma
    • B.A. Teicher S.A. Holden C.M. Rose Effect of Fluosol-DA/O2 on tumor cell and bone marrow cytotoxicity of nitrosoureas in mice bearing FSall fibrosarcoma Int J Cancer 38 1986 285 288
    • (1986) Int J Cancer , vol.38 , pp. 285-288
    • Teicher, B.A.1    Holden, S.A.2    Rose, C.M.3
  • 142
    • 0022401539 scopus 로고
    • Effect of oxygen on the cytotoxicity and antitumor activity of etoposide
    • B.A. Teicher S.A. Holden C.M. Rose Effect of oxygen on the cytotoxicity and antitumor activity of etoposide J Natl Cancer Inst 75 1985 1129 1133
    • (1985) J Natl Cancer Inst , vol.75 , pp. 1129-1133
    • Teicher, B.A.1    Holden, S.A.2    Rose, C.M.3
  • 143
    • 0022898424 scopus 로고
    • Effect of Fluosol-DA/02 on the antitumor activity and pulmonary toxicity of bleomycin
    • B.A. Teicher J.S. Lazo W.W. Merrill Effect of Fluosol-DA/02 on the antitumor activity and pulmonary toxicity of bleomycin Cancer Chemother Pharmacol 18 1986 213 218
    • (1986) Cancer Chemother Pharmacol , vol.18 , pp. 213-218
    • Teicher, B.A.1    Lazo, J.S.2    Merrill, W.W.3
  • 144
    • 0019349297 scopus 로고
    • Classification of antineoplastic agents by their selective toxicities toward oxygenated and hypoxic tumor cells
    • B.A. Teicher J.S. Lazo A.C. Sartorelli Classification of antineoplastic agents by their selective toxicities toward oxygenated and hypoxic tumor cells Cancer Res 41 1981 73 81
    • (1981) Cancer Res , vol.41 , pp. 73-81
    • Teicher, B.A.1    Lazo, J.S.2    Sartorelli, A.C.3
  • 145
    • 0023775083 scopus 로고
    • Effect of various oxygenation conditions and Fluosol-DA on cancer chemotherapeutic agents
    • B.A. Teicher N.L. Mclntosh-Lowe C.M. Rose Effect of various oxygenation conditions and Fluosol-DA on cancer chemotherapeutic agents Biomat Art Cells Immobiol Biotech 16 1988 533 546
    • (1988) Biomat Art Cells Immobiol Biotech , vol.16 , pp. 533-546
    • Teicher, B.A.1    Mclntosh-Lowe, N.L.2    Rose, C.M.3
  • 147
    • 85113059696 scopus 로고    scopus 로고
    • Teicher BA, Schwartz GN, Dupuis NP, et al: Oxygenation of human tumor xenografts in nude mice by a perfluorochemical emulsion and carbogen breathing. Biomat Art Cells Immobiol Biotech, in press.
  • 148
    • 0027531409 scopus 로고
    • Tumor oxygenation and radiosensitization by pentoxifylline and a perflubron emulsion/carbogen breathing
    • B.A. Teicher E.A. Sotomayor M.F. Robinson Tumor oxygenation and radiosensitization by pentoxifylline and a perflubron emulsion/carbogen breathing Int J Oncol 2 1993 13 21
    • (1993) Int J Oncol , vol.2 , pp. 13-21
    • Teicher, B.A.1    Sotomayor, E.A.2    Robinson, M.F.3
  • 149
    • 0024459584 scopus 로고
    • Evidence for enzymatic activation and oxygen involvement in cytotoxicity and antitumor activity of N, N′ N″- triethylenethi- ophosphoramide
    • B.A. Teicher D.J. Waxman S.A. Holden Evidence for enzymatic activation and oxygen involvement in cytotoxicity and antitumor activity of N, N′ N″- triethylenethi- ophosphoramide Cancer Res 49 1989 4996 5001
    • (1989) Cancer Res , vol.49 , pp. 4996-5001
    • Teicher, B.A.1    Waxman, D.J.2    Holden, S.A.3
  • 150
    • 0026531273 scopus 로고
    • Use of fluorine-19 nuclear magnetic resonsance spectroscopy and hydralazine for measuring dynamic changes in blood perfusion volume in tumors in mice
    • C. Thomas C. Counsell P. Wood Use of fluorine-19 nuclear magnetic resonsance spectroscopy and hydralazine for measuring dynamic changes in blood perfusion volume in tumors in mice J Natl Cancer Inst 84 1992 174 180
    • (1992) J Natl Cancer Inst , vol.84 , pp. 174-180
    • Thomas, C.1    Counsell, C.2    Wood, P.3
  • 151
    • 0343623888 scopus 로고
    • Conference on time and dose relationships in radiation biology as applied to radiotherapy
    • R.H. Thomlinson Conference on time and dose relationships in radiation biology as applied to radiotherapy 1970 Brookhaven Natl Lab Rep Springfield, VA 242 247
    • (1970) , pp. 242-247
    • Thomlinson, R.H.1
  • 152
    • 0014067312 scopus 로고
    • The gross response of an experimental tumour to single doses of x-ray
    • R.H. Thomlinson E.A. Craddock The gross response of an experimental tumour to single doses of x-ray Br J Cancer 21 1967 108 123
    • (1967) Br J Cancer , vol.21 , pp. 108-123
    • Thomlinson, R.H.1    Craddock, E.A.2
  • 153
    • 0025737554 scopus 로고
    • The effect of angiotensin II on intermittent tumour blood flow and acute hypoxia in the murine SCVH carcinoma
    • M.J. Trotter D.J. Chaplin P.L. Olive The effect of angiotensin II on intermittent tumour blood flow and acute hypoxia in the murine SCVH carcinoma Eur J Cancer 27 1991 887 893
    • (1991) Eur J Cancer , vol.27 , pp. 887-893
    • Trotter, M.J.1    Chaplin, D.J.2    Olive, P.L.3
  • 154
    • 0017210392 scopus 로고
    • Comparative chemosensitivity of exponential versus plateau-phase cells in both in vitro and in vivo model systems
    • P.R. Twentyman Comparative chemosensitivity of exponential versus plateau-phase cells in both in vitro and in vivo model systems Cancer Treatment Reports 60 1976 1719 1722
    • (1976) Cancer Treatment Reports , vol.60 , pp. 1719-1722
    • Twentyman, P.R.1
  • 155
    • 0014278615 scopus 로고
    • Tumor reoxygenation during fractionated radiotherapy: Studies with a transplantable mouse osteosarcoma
    • L.M. Van Putten Tumor reoxygenation during fractionated radiotherapy: Studies with a transplantable mouse osteosarcoma Eur J Cancer 4 1968 173 182
    • (1968) Eur J Cancer , vol.4 , pp. 173-182
    • Van Putten, L.M.1
  • 156
    • 0014266140 scopus 로고
    • Oxygenation status of a transplantable tumor during fractionated radiation therapy
    • L.M. Van Putten R.F. Kallman Oxygenation status of a transplantable tumor during fractionated radiation therapy J Natl Cancer Inst 40 1968 441 451
    • (1968) J Natl Cancer Inst , vol.40 , pp. 441-451
    • Van Putten, L.M.1    Kallman, R.F.2
  • 157
    • 0017645626 scopus 로고
    • Hypoxia and neoplastic tissue
    • P. Vaupel Hypoxia and neoplastic tissue Microvasc Res 13 1977 399 408
    • (1977) Microvasc Res , vol.13 , pp. 399-408
    • Vaupel, P.1
  • 158
    • 0025329088 scopus 로고
    • Oxygenation of human tumors
    • P. Vaupel Oxygenation of human tumors Strahlenther Onkol 166 1990 377 386
    • (1990) Strahlenther Onkol , vol.166 , pp. 377-386
    • Vaupel, P.1
  • 159
    • 0002972851 scopus 로고
    • Oxygenation of solid tumors
    • P. Vaupel Oxygenation of solid tumors B.A. Teicher Drug Resistance in Oncology 1993 Marcel-Dekker New York 53 85
    • (1993) , pp. 53-85
    • Vaupel, P.1
  • 160
    • 0023077455 scopus 로고
    • Blood flow, vascular resistance and oxygen availability in malignant tumours upon intravenous flunarizine
    • P. Vaupel H. Menke Blood flow, vascular resistance and oxygen availability in malignant tumours upon intravenous flunarizine Adv Exp Med Biol 215 1987 393 398
    • (1987) Adv Exp Med Biol , vol.215 , pp. 393-398
    • Vaupel, P.1    Menke, H.2
  • 161
    • 0012257052 scopus 로고
    • Effect of various calcium antagonists on blood flow and red blood cell flux in malignant tumors
    • P. Vaupel H. Menke Effect of various calcium antagonists on blood flow and red blood cell flux in malignant tumors Progress in Applied Microcirculation 14 1989 88 103
    • (1989) Progress in Applied Microcirculation , vol.14 , pp. 88-103
    • Vaupel, P.1    Menke, H.2
  • 162
    • 0023227393 scopus 로고
    • Blood flow, oxygen consumption and tissue oxygenation of human breast cancer xenografts in nude rats
    • P. Vaupel H.P. Fortmeyer S. Runkel Blood flow, oxygen consumption and tissue oxygenation of human breast cancer xenografts in nude rats Cancer Res 47 1987 3496 3503
    • (1987) Cancer Res , vol.47 , pp. 3496-3503
    • Vaupel, P.1    Fortmeyer, H.P.2    Runkel, S.3
  • 163
    • 0019461848 scopus 로고
    • Heterogeneous oxygen partial pressure and pH distribution C3H mouse mammary adenocarcinoma
    • P. Vaupel S. Frinak H.I. Bicher Heterogeneous oxygen partial pressure and pH distribution C3H mouse mammary adenocarcinoma Cancer Res 41 1981 2008 2013
    • (1981) Cancer Res , vol.41 , pp. 2008-2013
    • Vaupel, P.1    Frinak, S.2    Bicher, H.I.3
  • 164
    • 0024408986 scopus 로고
    • Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: A review
    • P. Vaupel F. Kallinowski P. Okunieff Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: A review Cancer Res 49 1989 6449 6465
    • (1989) Cancer Res , vol.49 , pp. 6449-6465
    • Vaupel, P.1    Kallinowski, F.2    Okunieff, P.3
  • 165
    • 0024854226 scopus 로고
    • Correlations between 31p-NMR spectroscopy and tissue O2 tension measurements in a murine fibrosarcoma
    • P. Vaupel P. Okunieff F. Kallinowski Correlations between 31p-NMR spectroscopy and tissue O2 tension measurements in a murine fibrosarcoma Radiat Res 120 1989 477 493
    • (1989) Radiat Res , vol.120 , pp. 477-493
    • Vaupel, P.1    Okunieff, P.2    Kallinowski, F.3
  • 166
    • 0027056686 scopus 로고
    • Blood flow and tissue oxygenation of human tumors: An update
    • P. Vaupel K. Schienger M. Hoeckel Blood flow and tissue oxygenation of human tumors: An update Adv Exp Med Biol 316 1992 361 371
    • (1992) Adv Exp Med Biol , vol.316 , pp. 361-371
    • Vaupel, P.1    Schienger, K.2    Hoeckel, M.3
  • 167
    • 0025807618 scopus 로고
    • Oxygenation of human tumors: Evaluation of tissue oxygen distribution in breast cancer by computerized O2 tension measurements
    • P. Vaupel K. Schienger C. Knoop Oxygenation of human tumors: Evaluation of tissue oxygen distribution in breast cancer by computerized O2 tension measurements Cancer Res 51 1991 3316 3322
    • (1991) Cancer Res , vol.51 , pp. 3316-3322
    • Vaupel, P.1    Schienger, K.2    Knoop, C.3
  • 168
    • 0027258630 scopus 로고
    • Radiosensitivity, blood perfusion and tumour oxygenation after perflubron emulsion injection
    • L. Vitu-Loas C. Thomas N. Chavaudra Radiosensitivity, blood perfusion and tumour oxygenation after perflubron emulsion injection Radiother Oncol 27 1993 149 155
    • (1993) Radiother Oncol , vol.27 , pp. 149-155
    • Vitu-Loas, L.1    Thomas, C.2    Chavaudra, N.3
  • 169
    • 0024352362 scopus 로고
    • Calcium antagonists as radiation modifiers: Site specificity in relation to tumor response
    • P.J. Wood D.G. Hirst Calcium antagonists as radiation modifiers: Site specificity in relation to tumor response Int J Radiat Oncol Biol Phys 16 1989 1141 1144
    • (1989) Int J Radiat Oncol Biol Phys , vol.16 , pp. 1141-1144
    • Wood, P.J.1    Hirst, D.G.2
  • 170
    • 0024263005 scopus 로고
    • Cinnarizine and flunarizine as radiation sensitizers in two murine tumours
    • P.J. Wood D.G. Hirst Cinnarizine and flunarizine as radiation sensitizers in two murine tumours Br J Cancer 58 1989 742 745
    • (1989) Br J Cancer , vol.58 , pp. 742-745
    • Wood, P.J.1    Hirst, D.G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.